A PET study of D1-like dopamine receptor ligand binding during altered endogenous dopamine levels in the primate brain

Psychopharmacology

Volumn 146, Issue 2, 1999, Pages 220-227

  Chou, Yuan Hwa ^a   Karlsson, Per ^a   Halldin, Christer ^a   Olsson, Hans ^a   Farde, Lars ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

11C NNC 112; Amphetamine; D1 dopamine receptor; Endogenous dopamine; Positron emission tomography; Reserpine

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; 8 CHLORO 5 (7 BENZOFURANYL) 7 HYDROXY 3 METHYL 2,3,4,5 TETRA HYDRO 1H 3 BENZAZEPINE; CARBON 11; DOPAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; RACLOPRIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DOPAMINERGIC SYSTEM; DRUG RECEPTOR BINDING; ISOTOPE LABELING; LIGAND BINDING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIMATE; PRIORITY JOURNAL; RECEPTOR OCCUPANCY;

(R)-2,3,4,5-TETRAHYDRO-8-CHLORO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL; ALGORITHMS; AMPHETAMINE; ANIMALS; BENZAZEPINES; BENZOFURANS; BRAIN; BRAIN CHEMISTRY; CEREBELLUM; DOPAMINE; DOPAMINE ANTAGONISTS; DOPAMINE UPTAKE INHIBITORS; LIGANDS; MACACA FASCICULARIS; NEOCORTEX; NEOSTRIATUM; RECEPTORS, DOPAMINE D1; RESERPINE; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0032881922     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130051110     Document Type: Article

References (44)

1. 1A dopamine receptor staining. Synapse 27:313-321
2. Berglund M, Risberg J (1980) Regional cerebral blood flow in a case of amphetamine intoxication. Psychopharmacology 70:219-221
3. Breier A, Su TP, Saunders R, Carson RE, Kolachana BS, de Bartolomeis A, Weinberger DR, Weisenfeld N, Malhotra AK, Eckelman WC, Pickar D (1997) Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: evidence from a novel positron emission tomography method. Proc Natl Acad Sci USA 94:2569-2574
4. 1 dopamine receptor immunoreactivity in rat striatonigral neurons and its relation with dopaminergic innervation. Brain Res 730:17-31
5. 1 receptor tracer, in normal subjects. J Nucl Med 39:792-797
6. 3H]spiperone binding: evidence for accumulation in corpus striatum by agonist-mediated receptor internalization. J Cereb Blood Flow Metab 8:291-303
7. De Lean A, Stadel JM, Lefkowitz RJ (1980) A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor. J Biol Chem 255:7108-7117
8. 11C-raclopride is altered by drugs that modify synaptic dopamine levels. Synapse 13:350-356
9. 1 dopamine receptor in striatal neurons in vivo as evidence of activation by dopamine agonists. J Neurosci 18:1650-1661
10. 2 dopamine receptor binding in the living human brain by PET. Science 231:258-261
11. 11C-raclopride. Psychopharmacology 92:278-284
12. 2-dopamine receptors studied by PET - a comparison to the equilibrium analysis. J Cereb Blood Flow Metab 9:696-708
13. 11C]raclopride. Arch Gen Psychiatry 47:213-219
14. 2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine. Relation to extrapyramidal side effects. Arch Gen Psychiatry 49:538-544
15. 11C]raclopride in man. Synapse 20:200-208
16. 2 receptor binding in risperidone-treated schizophrenic patients. J Clin Psychopharmacol 15:19S-23S
17. Gingrich JA, Caron MG (1993) Recent advances in the molecular biology of dopamine receptors. Annu Rev Neurosci 16:299-321
18. 2-dopamine receptors in the monkey brain. Synapse 25:321-325
19. Guix T, Hurd YL, Ungerstedt U (1992) Amphetamine enhances extracellular concentrations of dopamine and acetylcholine in dorsolateral striamm and nucleus accumbens of freely moving rats. Neurosci Lett 138:137-340
20. 11C-labelled SCH 23390 for the in vivo study of dopamine D-1 receptors using positron emission tomography. Int J Rad Appl Instrum [A] 37:1039-1043
21. Halldin C, Foged C, Chou YH, Karlsson P, Swahn CG, Sandell J, Sedvall G, Farde L (1998) Carbon-11-NNC 112: a radioligand for PET examination of striatal and neocortical D-1-dopamine receptors. J Nucl Med 39:2061-2068
22. 2 dopamine receptor proteins in the dorsal striatum and their synaptic relationships with motor corticostriatal afferents. J Neurosci 15:5222-5237
23. Hume SP, Myers R, Bloomfield PM, Opacka-Juffry J, Cremer JE, Ahier RG, Luthra SK, Brooks DJ, Lammertsma AA (1992) Quantitation of carbon-11-labeled raclopride in rat striatum using positron emission tomography. Synapse 12:47-54
24. Ito H, Hietala J, Blomqvist G, Halldin C, Farde L (1998) Comparison of the transient equilibrium and continuous infusion method for quantitative PET analysis of [C-11]raclopride binding. J Cereb Blood Flow Metab 18:941-950
25. Jackson DM, Westlind-Danielsson A (1994) Dopamine receptors: molecular biology, biochemistry and behavioural aspects. Pharmacol Ther 64:291-370
26. 1-dopamine receptor. Psychopharmacology 113:149-56
27. Kuczenski R (1977) Differential effects of reserpine and tetrabenazine on rat striatal synaptosomal dopamine biosynthesis and synaptosomal dopamine pools. J Pharmacol Exp Ther 201:357-367
28. Laruelle M, Abi-Dargham A, van Dyck CH, Gil R, D'Souza CD, Erdos J, McCance E, Rosenblatt W, Fingado C, Zoghbi SS, Baldwin RM, Seibyl JP, Krystal JH, Charney DS, Innis RB (1996) Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects. Proc Natl Acad Sci USA 93:9235-9240
29. 2 dopamine receptors in brain with subtype-specific antibodies. Proc Natl Acad Sci USA 90:8861-8865
30. 18F]N-methylspiroperidol binding in the basal ganglia: comparison of simulations and experimental results from PET studies in baboons. Synapse 9:195-207
31. 1 receptors in schizophrenia. Eur J Pharmacol 233:175-176
32. 2 interactions. Neuropharmacology 34:777-783
33. McCulloch J, Deshmukh VD, Harper AM (1977) Indirect sympathomimetics and cerebral blood flow and metabolism. Acta Neurol Scand Suppl 64:94-95
34. 18F-fallypride in nonhuman primates using positron emission tomography. Synapse 27:1-13
35. Naudon L, Leroux-Nicollet I, Raisman-Vozari R, Botton D, Costentin J (1995) Time-course of modifications elicited by reserpine on the density and mRNA synthesis of the vesicular monoamine transporter, and on the density of the membrane dopamine uptake complex. Synapse 21:29-36
36. 2 receptor occupancy in relation to clozapine serum concentration: a PET study of schizophrenic patients [see comments]. Am J Psychiatry 152:1444-1449
37. 1 receptors in schizophrenia revealed by PET. Nature 385:634-636
38. 2 receptors in the rat central nervous system. Neuroscience 30:767-777
39. 1 dopamine receptors in prefrontal cortex: involvement in working memory. Science 251:947-950
40. 1 dopamine receptor immunoreactivity in human and monkey cerebral cortex: predominant and extrasynaptic localization in dendritic spines. Proc Natl Acad Sci USA 91:5720-5724
41. 11C] raclopride in the human brain. Synapse 16:255-262
42. Waddington JL, Daly SA, Downes RP, Deveney AM, McCauley PG, O'Boyle KM (1995)Behavioural pharmacology of "D-1-like" dopamine receptors: further subtyping, new pharmacological probes and interactions with "D-2-like" receptors. Prog Neuropsychopharmacol Biol Psychiatry 19:811-831
43. Wienhard K, Dahlbom M, Eriksson L, Michel C, Bruckbauer T, Pietrzyk U, Heiss WD (1994) The ECAT EXACT HR: performance of a new high resolution positron scanner. J Comput Assist Tomogr 18:110-118
44. Williams GV, Goldman-Rakic PS (1995) Modulation of memory fields by dopamine D receptors in prefrontal cortex [see comments]. Nature 376:572-575