BSEP inhibition – In vitro screens to assess cholestatic potential of drugs

Toxicology in Vitro

Volumn 26, Issue 8, 2012, Pages 1294-1299

  Kis, Emese ^a   Ioja, Enikő ^a   Rajnai, Zsuzsa ^a   Jani, Márton ^a   Méhn, Dóra ^a   Herédi Szabó, Krisztina ^a   Krajcsi, Peter ^a  

^a SOLVO BIOTECHNOLOGY   (Hungary)

Author keywords

Bile salt; BSEP; Cholestasis; Drug induced liver injury; Toxicity; Transporter

Indexed keywords

BILE ACID; BILE SALT; BILE SALT EXPORT PUMP; BOSENTAN; CLOFAZIMINE; CYCLOSPORINE; ERYTHROMYCIN ESTOLATE; GEFITINIB; GLIBENCLAMIDE; GLIMEPIRIDE; IMATINIB; INDINAVIR; ITRACONAZOLE; KETOCONAZOLE; LAPATINIB; LOPINAVIR; NEFAZODONE; NICARDIPINE; PAZOPANIB; PIOGLITAZONE; RESERPINE; RITONAVIR; SAQUINAVIR; SORAFENIB; STAUROSPORINE; TELITHROMYCIN; TROGLITAZONE; UNINDEXED DRUG; VALINOMYCIN; WORTMANNIN; ABC TRANSPORTER; ABCB11 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CHOLESTASIS; CONTROLLED STUDY; DRUG DEVELOPMENT; DRUG SCREENING; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL; LIVER INJURY; LIVER TOXICITY; LIVER TRANSPLANTATION; NONHUMAN; PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS TYPE 2; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SPECIES DIFFERENCE; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG DESIGN; GENETICS; METABOLISM; PATHOPHYSIOLOGY; REVIEW; SEVERITY OF ILLNESS INDEX; TOXIC HEPATITIS;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BILE ACIDS AND SALTS; CHOLESTASIS; CHOLESTASIS, INTRAHEPATIC; DRUG DESIGN; DRUG-INDUCED LIVER INJURY; HUMANS; SEVERITY OF ILLNESS INDEX; SPECIES SPECIFICITY;

EID: 82455203879     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2011.11.002     Document Type: Article

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