Characterization of sandwich-cultured hepatocytes as an in vitro model to assess the hepatobiliary disposition of copper

Drug Metabolism and Disposition

Volumn 37, Issue 5, 2009, Pages 969-976

  Ansede, John H ^a   Wright, Matthew R ^b   Claire III, Robert L St ^a   Hart, Robert W ^a   Gefroh, Holly A ^a   Brouwer, Kenneth R ^a  

^a Qualyst Inc   (United States)

^b GILEAD SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 (1,1 DIOXIDO 1,2 THIAZINAN 2 YL) N (4 FLUOROBENZYL) 8 HYDROXY 1,6 NAPHTHYRIDINE 7 CARBOXAMIDE; AMIDE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CARRIER PROTEIN; CERULOPLASMIN; COPPER; COPPER UPTAKE TRANSPORTER 1; L 000870810; UNCLASSIFIED DRUG; WILSON DISEASE PROTEIN;

ANIMAL CELL; ARTICLE; BILIARY EXCRETION; CONTROLLED STUDY; CULTURE TECHNIQUE; DOG; EXPERIMENTAL MODEL; HUMAN; INCUBATION TIME; LIVER CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SANDWICH LIVER CELL CULTURE; SPECIES DIFFERENCE;

ADENOSINE TRIPHOSPHATASES; ANIMALS; ANTI-HIV AGENTS; BILE; BLOTTING, WESTERN; CATION TRANSPORT PROTEINS; CELLS, CULTURED; CERULOPLASMIN; COPPER; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEPATOCYTES; HUMANS; LIVER; MALE; RATS; RATS, WISTAR;

CANIS FAMILIARIS; RATTUS;

EID: 66449111888     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.108.024638     Document Type: Article

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