-
3
-
-
0034668187
-
Signaling angiogenesis via p42/p44 MAP kinase and hypoxia
-
Berra E, Milanini J, Richard DE, Le Gall M, Vinals F, Gothie E, Roux D, Pages G, Pouyssegur J,. Signaling angiogenesis via p42/p44 MAP kinase and hypoxia. Biochem Pharmacol 2000; 60: 1171-8.
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 1171-1178
-
-
Berra, E.1
Milanini, J.2
Richard, D.E.3
Le Gall, M.4
Vinals, F.5
Gothie, E.6
Roux, D.7
Pages, G.8
Pouyssegur, J.9
-
4
-
-
0034098405
-
Signaling angiogenesis via p42/p44 MAP kinase cascade
-
Pages G, Milanini J, Richard DE, Berra E, Gothie E, Vinals F, Pouyssegur J,. Signaling angiogenesis via p42/p44 MAP kinase cascade. Ann N Y Acad Sci 2000; 902: 187-200. (Pubitemid 30389123)
-
(2000)
Annals of the New York Academy of Sciences
, vol.902
, pp. 187-200
-
-
Pages, G.1
Milanini, J.2
Richard, D.E.3
Berra, E.4
Gothie, E.5
Vinals, F.6
Pouyssegur, J.7
-
5
-
-
0034464872
-
Hypoxia, HIF-1, and the pathophysiology of common human diseases
-
Semenza GL, Agani F, Feldser D, Iyer N, Kotch L, Laughner E, Yu A,. Hypoxia, HIF-1, and the pathophysiology of common human diseases. Adv Exp Med Biol 2000; 475: 123-30. (Pubitemid 32197719)
-
(2000)
Advances in Experimental Medicine and Biology
, vol.475
, pp. 123-130
-
-
Semenza, G.L.1
Agani, F.2
Feldser, D.3
Iyer, N.4
Kotch, L.5
Laughner, E.6
Yu, A.7
-
6
-
-
4444324696
-
VEGF, VEGFRs expressions and activated STATs in ovarian epithelial carcinoma
-
DOI 10.1016/j.ygyno.2004.05.056, PII S0090825804003488
-
Chen H, Ye D, Xie X, Chen B, Lu W,. VEGF, VEGFRs expressions and activated STATs in ovarian epithelial carcinoma. Gynecol Oncol 2004; 94: 630-5. (Pubitemid 39194453)
-
(2004)
Gynecologic Oncology
, vol.94
, Issue.3
, pp. 630-635
-
-
Chen, H.1
Ye, D.2
Xie, X.3
Chen, B.4
Lu, W.5
-
8
-
-
0032590011
-
PlK3CA is implicated as an oncogene in ovarian cancer
-
DOI 10.1038/5042
-
Shayesteh L, Lu Y, Kuo WL, Baldocchi R, Godfrey T, Collins C, Pinkel D, Powell B, Mills GB, Gray JW,. PIK3CA is implicated as an oncogene in ovarian cancer. Nat Genet 1999; 21: 99-102. (Pubitemid 29036292)
-
(1999)
Nature Genetics
, vol.21
, Issue.1
, pp. 99-102
-
-
Shayesteh, L.1
Lu, Y.2
Kuo, W.-L.3
Baldocchi, R.4
Godfrey, T.5
Collins, C.6
Pinkel, D.7
Powell, B.8
Mills, G.B.9
Gray, J.W.10
-
9
-
-
33846252336
-
2-M phase transition
-
DOI 10.1158/0008-5472.CAN-06-1968
-
Cristiano BE, Chan JC, Hannan KM, Lundie NA, Marmy-Conus NJ, Campbell IG, Phillips WA, Robbie M, Hannan RD, Pearson RB,. A specific role for AKT3 in the genesis of ovarian cancer through modulation of G(2)-M phase transition. Cancer Res 2006; 66: 11718-25. (Pubitemid 46094184)
-
(2006)
Cancer Research
, vol.66
, Issue.24
, pp. 11718-11725
-
-
Cristiano, B.E.1
Chan, J.C.2
Hannan, K.M.3
Lundie, N.A.4
Marmy-Conus, N.J.5
Campbell, I.G.6
Phillips, W.A.7
Robbie, M.8
Hannan, R.D.9
Pearson, R.B.10
-
10
-
-
0030884103
-
PKB/Akt: Connecting phosphoinositide 3-kinase to cell survival and beyond
-
Marte BM, Downward J,. PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond. Trends Biochem Sci 1997; 22: 355-8.
-
(1997)
Trends Biochem Sci
, vol.22
, pp. 355-358
-
-
Marte, B.M.1
Downward, J.2
-
11
-
-
0028838845
-
A target for phosphoinositide 3-kinase: Akt/PKB
-
Bos JL,. A target for phosphoinositide 3-kinase: Akt/PKB. Trends Biochem Sci 1995; 20: 441-2.
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 441-442
-
-
Bos, J.L.1
-
12
-
-
33846416534
-
Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/Neu and MMTV-polyoma middle T transgenic mice
-
DOI 10.1158/0008-5472.CAN-06-3782
-
Maroulakou IG, Oemler W, Naber SP, Tsichlis PN,. Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice. Cancer Res 2007; 67: 167-77. (Pubitemid 46142772)
-
(2007)
Cancer Research
, vol.67
, Issue.1
, pp. 167-177
-
-
Maroulakou, I.G.1
Oemler, W.2
Naber, S.P.3
Tsichlis, P.N.4
-
13
-
-
1242286948
-
Frequent activation of AKT2 kinase in human pancreatic carcinomas
-
Altomare DA, Tanno S, De Rienzo A, Klein-Szanto AJ, Tanno S, Skele KL, Hoffman JP, Testa JR,. Frequent activation of AKT2 kinase in human pancreatic carcinomas. J Cell Biochem 2002; 87: 470-6.
-
(2002)
J Cell Biochem
, vol.87
, pp. 470-476
-
-
Altomare, D.A.1
Tanno, S.2
De Rienzo, A.3
Klein-Szanto, A.J.4
Tanno, S.5
Skele, K.L.6
Hoffman, J.P.7
Testa, J.R.8
-
14
-
-
0001457668
-
Amplification of AKT2 in human pancreatic cancer cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA
-
DOI 10.1073/pnas.93.8.3636
-
Cheng JQ, Ruggeri B, Klein WM, Sonoda G, Altomare DA, Watson DK, Testa JR,. Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA. Proc Natl Acad Sci U S A 1996; 93: 3636-41. (Pubitemid 26127592)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.8
, pp. 3636-3641
-
-
Cheng, J.Q.1
Ruggeri, B.2
Klein, W.M.3
Sonoda, G.4
Altomare, D.A.5
Watson, D.K.6
Testa, J.R.7
-
15
-
-
58149503692
-
Akt2 overexpression plays a critical role in the establishment of colorectal cancer metastasis
-
Rychahou PG, Kang J, Gulhati P, Doan HQ, Chen LA, Xiao SY, Chung DH, Evers BM,. Akt2 overexpression plays a critical role in the establishment of colorectal cancer metastasis. Proc Natl Acad Sci U S A 2008; 105: 20315-20.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 20315-20320
-
-
Rychahou, P.G.1
Kang, J.2
Gulhati, P.3
Doan, H.Q.4
Chen, L.A.5
Xiao, S.Y.6
Chung, D.H.7
Evers, B.M.8
-
16
-
-
53849132331
-
A novel AKT3 mutation in melanoma tumours and cell lines
-
Davies MA, Stemke-Hale K, Tellez C, Calderone TL, Deng W, Prieto VG, Lazar AJ, Gershenwald JE, Mills GB,. A novel AKT3 mutation in melanoma tumours and cell lines. Br J Cancer 2008; 99: 1265-8.
-
(2008)
Br J Cancer
, vol.99
, pp. 1265-1268
-
-
Davies, M.A.1
Stemke-Hale, K.2
Tellez, C.3
Calderone, T.L.4
Deng, W.5
Prieto, V.G.6
Lazar, A.J.7
Gershenwald, J.E.8
Mills, G.B.9
-
17
-
-
0034638623
-
Induction of hypoxia-inducible-factor 1 by nitric oxide is mediated via the PI 3K pathway
-
Sandau KB, Faus HG, Brune B,. Induction of hypoxia-inducible-factor 1 by nitric oxide is mediated via the PI 3K pathway. Biochem Biophys Res Commun 2000; 278: 263-7.
-
(2000)
Biochem Biophys Res Commun
, vol.278
, pp. 263-267
-
-
Sandau, K.B.1
Faus, H.G.2
Brune, B.3
-
18
-
-
0030869787
-
Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras- transformed cells through a hypoxia inducible factor-1 transcriptional element
-
Mazure NM, Chen EY, Laderoute KR, Giaccia AJ,. Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element. Blood 1997; 90: 3322-31. (Pubitemid 27473400)
-
(1997)
Blood
, vol.90
, Issue.9
, pp. 3322-3331
-
-
Mazure, N.M.1
Chen, E.Y.2
Laderoute, K.R.3
Giaccia, A.J.4
-
19
-
-
0033542476
-
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
-
Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM,. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 1999; 399: 601-5.
-
(1999)
Nature
, vol.399
, pp. 601-605
-
-
Dimmeler, S.1
Fleming, I.2
Fisslthaler, B.3
Hermann, C.4
Busse, R.5
Zeiher, A.M.6
-
20
-
-
2642597076
-
Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells
-
Papapetropoulos A, Garcia-Cardena G, Madri JA, Sessa WC,. Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells. J Clin Invest 1997; 100: 3131-9. (Pubitemid 28022851)
-
(1997)
Journal of Clinical Investigation
, vol.100
, Issue.12
, pp. 3131-3139
-
-
Papapetropoulos, A.1
Garcia-Cardena, G.2
Madri, J.A.3
Sessa, W.C.4
-
21
-
-
20044382806
-
Role for Akt3/protein kinase by in attainment of normal brain size
-
DOI 10.1128/MCB.25.5.1869-1878.2005
-
Easton RM, Cho H, Roovers K, Shineman DW, Mizrahi M, Forman MS, Lee VM, Szabolcs M, de Jong R, Oltersdorf T, Ludwig T, Efstratiadis A, et al. Role for Akt3/protein kinase Bgamma in attainment of normal brain size. Mol Cell Biol 2005; 25: 1869-78. (Pubitemid 40280150)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.5
, pp. 1869-1878
-
-
Easton, R.M.1
Cho, H.2
Roovers, K.3
Shineman, D.W.4
Mizrahi, M.5
Forman, M.S.6
Lee, V.M.-Y.7
Szabolcs, M.8
De Jong, R.9
Oltersdorf, T.10
Ludwig, T.11
Efstratiadis, A.12
Birnbaum, M.J.13
-
22
-
-
23144449547
-
Essential role of protein kinase Bγ (PKBγ/Akt3) in postnatal brain developmental but not in glucose homeostasis
-
DOI 10.1242/dev.01864
-
Tschopp O, Yang ZZ, Brodbeck D, Dummler BA, Hemmings-Mieszczak M, Watanabe T, Michaelis T, Frahm J, Hemmings BA,. Essential role of protein kinase B gamma (PKB gamma/Akt3) in postnatal brain development but not in glucose homeostasis. Development 2005; 132: 2943-54. (Pubitemid 41086730)
-
(2005)
Development
, vol.132
, Issue.13
, pp. 2943-2954
-
-
Tschopp, O.1
Yang, Z.-Z.2
Brodbeck, D.3
Dummler, B.A.4
Hemmings-Mieszczak, M.5
Watanabe, T.6
Michaelis, T.7
Frahm, J.8
Hemmings, B.A.9
-
23
-
-
51349085937
-
VEGF stimulation of mitochondrial biogenesis: Requirement of AKT3 kinase
-
Wright GL, Maroulakou IG, Eldridge J, Liby TL, Sridharan V, Tsichlis PN, Muise-Helmericks RC,. VEGF stimulation of mitochondrial biogenesis: requirement of AKT3 kinase. Faseb J 2008.
-
(2008)
Faseb J
-
-
Wright, G.L.1
Maroulakou, I.G.2
Eldridge, J.3
Liby, T.L.4
Sridharan, V.5
Tsichlis, P.N.6
Muise-Helmericks, R.C.7
-
25
-
-
35648957759
-
Biologic significance of receptor-binding cancer antigen expressed on SiSo cells (RCAS1) as a pivotal regulator of tumor growth through angiogenesis in human uterine cancer
-
DOI 10.1002/cncr.23015
-
Sonoda K, Miyamoto S, Yamazaki A, Kobayashi H, Nakashima M, Mekada E, Wake N,. Biologic significance of receptor-binding cancer antigen expressed on SiSo cells (RCAS1) as a pivotal regulator of tumor growth through angiogenesis in human uterine cancer. Cancer 2007; 110: 1979-90. (Pubitemid 350036857)
-
(2007)
Cancer
, vol.110
, Issue.9
, pp. 1979-1990
-
-
Sonoda, K.1
Miyamoto, S.2
Yamazaki, A.3
Kobayashi, H.4
Nakashima, M.5
Mekada, E.6
Wake, N.7
-
26
-
-
26844565041
-
Reevaluation of the 22-1-1 antibody and its putative antigen, EBAG9/RCAS1, as a tumor marker
-
Reimer TA, Anagnostopoulos I, Erdmann B, Lehmann I, Stein H, Daniel P, Dorken B, Rehm A,. Reevaluation of the 22-1-1 antibody and its putative antigen, EBAG9/RCAS1, as a tumor marker. BMC Cancer 2005; 5: 47.
-
(2005)
BMC Cancer
, vol.5
, pp. 47
-
-
Reimer, T.A.1
Anagnostopoulos, I.2
Erdmann, B.3
Lehmann, I.4
Stein, H.5
Daniel, P.6
Dorken, B.7
Rehm, A.8
-
27
-
-
31544480052
-
Diagnostic markers of ovarian cancer by high-throughput antigen cloning and detection on arrays
-
DOI 10.1158/0008-5472.CAN-04-2962
-
Chatterjee M, Mohapatra S, Ionan A, Bawa G, Ali-Fehmi R, Wang X, Nowak J, Ye B, Nahhas FA, Lu K, Witkin SS, Fishman D, et al. Diagnostic markers of ovarian cancer by high-throughput antigen cloning and detection on arrays. Cancer Res 2006; 66: 1181-90. (Pubitemid 43165989)
-
(2006)
Cancer Research
, vol.66
, Issue.2
, pp. 1181-1190
-
-
Chatterjee, M.1
Mohapatra, S.2
Ionan, A.3
Bawa, G.4
Ali-Fehmi, R.5
Wang, X.6
Nowak, J.7
Ye, B.8
Nahhas, F.A.9
Lu, K.10
Witkin, S.S.11
Fishman, D.12
Munkarah, A.13
Morris, R.14
Levin, N.K.15
Shirley, N.N.16
Tromp, G.17
Abrams, J.18
Draghici, S.19
Tainsky, M.A.20
more..
-
28
-
-
0036073582
-
RCAS1 is associated with ductal breast cancer progression
-
DOI 10.1016/S0006-291X(02)00401-1, PII S0006291X02004011
-
Rousseau J, Tetu B, Caron D, Malenfant P, Cattaruzzi P, Audette M, Doillon C, Tremblay JP, Guerette B,. RCAS1 is associated with ductal breast cancer progression. Biochem Biophys Res Commun 2002; 293: 1544-9. (Pubitemid 34681054)
-
(2002)
Biochemical and Biophysical Research Communications
, vol.293
, Issue.5
, pp. 1544-1549
-
-
Rousseau, J.1
Tetu, B.2
Caron, D.3
Malenfant, P.4
Cattaruzzi, P.5
Audette, M.6
Doillon, C.7
Tremblay, J.P.8
Guerette, B.9
-
29
-
-
0035954822
-
Expression of a tumor-associated antigen RCAS1 in hepatocellular carcinoma
-
DOI 10.1016/S0304-3835(01)00541-9, PII S0304383501005419
-
Noguchi K, Enjoji M, Nakamuta M, Nakashima M, Nishi H, Choi I, Taguchi K, Kotoh K, Shimada M, Sugimachi K, Tsuneyoshi M, Nawata H, et al. Expression of a tumor-associated antigen RCAS1 in hepatocellular carcinoma. Cancer Lett 2001; 168: 197-202. (Pubitemid 32524282)
-
(2001)
Cancer Letters
, vol.168
, Issue.2
, pp. 197-202
-
-
Noguchi, K.-I.1
Enjoji, M.2
Nakamuta, M.3
Nakashima, M.4
Nishi, H.5
Choi, I.6
Taguchi, K.-I.7
Kotoh, K.8
Shimada, M.9
Sugimachi, K.10
Tsuneyoshi, M.11
Nawata, H.12
Watanabe, T.13
-
30
-
-
3042698999
-
Expression of EBAG9/RCASI is associated with advanced disease in human epithelial ovarian cancer
-
DOI 10.1038/sj.bjc.6601832
-
Akahira JI, Aoki M, Suzuki T, Moriya T, Niikura H, Ito K, Inoue S, Okamura K, Sasano H, Yaegashi N,. Expression of EBAG9/RCAS1 is associated with advanced disease in human epithelial ovarian cancer. Br J Cancer 2004; 90: 2197-202. (Pubitemid 38869730)
-
(2004)
British Journal of Cancer
, vol.90
, Issue.11
, pp. 2197-2202
-
-
Akahira, J.-I.1
Aoki, M.2
Suzuki, T.3
Moriya, T.4
Niikura, H.5
Ito, K.6
Inoue, S.7
Okamura, K.8
Sasano, H.9
Yaegashi, M.10
-
31
-
-
0032779988
-
Inhibition of cell growth and induction of apoptotic cell death by the human tumor-associated antigen RCAS1
-
DOI 10.1038/11383
-
Nakashima M, Sonoda K, Watanabe T,. Inhibition of cell growth and induction of apoptotic cell death by the human tumor-associated antigen RCAS1. Nat Med 1999; 5: 938-42. (Pubitemid 29372422)
-
(1999)
Nature Medicine
, vol.5
, Issue.8
, pp. 938-942
-
-
Nakashima, M.1
Sonoda, K.2
Watanabe, T.3
-
32
-
-
0038603867
-
The Golgi protein RCAS1 controls cell surface expression of tumor-associated O-linked glycan antigens
-
DOI 10.1074/jbc.M301361200
-
Engelsberg A, Hermosilla R, Karsten U, Schulein R, Dorken B, Rehm A,. The Golgi protein RCAS1 controls cell surface expression of tumor-associated O-linked glycan antigens. J Biol Chem 2003; 278: 22998-3007. (Pubitemid 36830365)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.25
, pp. 22998-23007
-
-
Engelsberg, A.1
Hermosilla, R.2
Karsten, U.3
Schulein, R.4
Dorken, B.5
Rehm, A.6
-
33
-
-
14844320520
-
EBAG9 adds a new layer of control on large dense-core vesicle exocytosis via interaction with snapin
-
DOI 10.1091/mbc.E04-09-0817
-
Ruder C, Reimer T, Delgado-Martinez I, Hermosilla R, Engelsberg A, Nehring R, Dorken B, Rehm A,. EBAG9 adds a new layer of control on large dense-core vesicle exocytosis via interaction with Snapin. Mol Biol Cell 2005; 16: 1245-57. (Pubitemid 40349561)
-
(2005)
Molecular Biology of the Cell
, vol.16
, Issue.3
, pp. 1245-1257
-
-
Ruder, C.1
Reimer, T.2
Delgado-Martinez, I.3
Hermosilla, R.4
Engelsberg, A.5
Nehring, R.6
Dorken, B.7
Rehm, A.8
-
34
-
-
33645211015
-
Modulation of total Akt kinase by increased expression of a single isoform: Requirement of the sphingosine-1-phosphate receptor, Edg3/S1P3, for the VEGF-dependent expression of Akt3 in primary endothelial cells
-
Fieber CB, Eldridge J, Taha TA, Obeid LM, Muise-Helmericks RC,. Modulation of total Akt kinase by increased expression of a single isoform: Requirement of the sphingosine-1-phosphate receptor, Edg3/S1P3, for the VEGF-dependent expression of Akt3 in primary endothelial cells. Exp Cell Res 2006; 312: 1164-73.
-
(2006)
Exp Cell Res
, vol.312
, pp. 1164-1173
-
-
Fieber, C.B.1
Eldridge, J.2
Taha, T.A.3
Obeid, L.M.4
Muise-Helmericks, R.C.5
-
35
-
-
61449091362
-
Mitochondrial DNA instability and metabolic shift in human cancers
-
Lee HC, Wei YH,. Mitochondrial DNA instability and metabolic shift in human cancers. Int J Mol Sci 2009; 10: 674-701.
-
(2009)
Int J Mol Sci
, vol.10
, pp. 674-701
-
-
Lee, H.C.1
Wei, Y.H.2
-
36
-
-
63849158757
-
Mitochondria: From bioenergetics to the metabolic regulation of carcinogenesis
-
Nadege B, Patrick L, Rodrigue R,. Mitochondria: from bioenergetics to the metabolic regulation of carcinogenesis. Front Biosci 2009; 14: 4015-34.
-
(2009)
Front Biosci
, vol.14
, pp. 4015-4034
-
-
Nadege, B.1
Patrick, L.2
Rodrigue, R.3
-
37
-
-
57849143324
-
Mitochondrial DNA mutations in cancer: A review
-
Santos C, Martinez M, Lima M, Hao YJ, Simoes N, Montiel R,. Mitochondrial DNA mutations in cancer: a review. Curr Top Med Chem 2008; 8: 1351-66.
-
(2008)
Curr Top Med Chem
, vol.8
, pp. 1351-1366
-
-
Santos, C.1
Martinez, M.2
Lima, M.3
Hao, Y.J.4
Simoes, N.5
Montiel, R.6
|