-
1
-
-
0030884103
-
PKB/Akt: Connecting phosphoinositide 3-kinase to cell survival and beyond
-
B.M. Marte, and J. Downward PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond Trends Biochem. Sci. 22 1997 355 358
-
(1997)
Trends Biochem. Sci.
, vol.22
, pp. 355-358
-
-
Marte, B.M.1
Downward, J.2
-
2
-
-
0028838845
-
A target for phosphoinositide 3-kinase: Akt/PKB
-
J.L. Bos A target for phosphoinositide 3-kinase: Akt/PKB Trends Biochem. Sci. 20 1995 441 442
-
(1995)
Trends Biochem. Sci.
, vol.20
, pp. 441-442
-
-
Bos, J.L.1
-
3
-
-
0038335334
-
PI3K/PTEN/AKT pathway. a critical mediator of oncogenic signaling
-
J. Paez, and W.R. Sellers PI3K/PTEN/AKT pathway. A critical mediator of oncogenic signaling Cancer Treat. Res. 115 2003 145 167
-
(2003)
Cancer Treat. Res.
, vol.115
, pp. 145-167
-
-
Paez, J.1
Sellers, W.R.2
-
4
-
-
0035499454
-
Ten years of protein kinase B signalling: A hard Akt to follow
-
D.P. Brazil, and B.A. Hemmings Ten years of protein kinase B signalling: a hard Akt to follow Trends Biochem. Sci. 26 2001 657 664
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 657-664
-
-
Brazil, D.P.1
Hemmings, B.A.2
-
5
-
-
0035936653
-
PDK2: A complex tail in one Akt
-
T.O. Chan, and P.N. Tsichlis PDK2: a complex tail in one Akt Sci. STKE 2001 2001 PE1
-
(2001)
Sci. STKE
, vol.2001
, pp. 1
-
-
Chan, T.O.1
Tsichlis, P.N.2
-
6
-
-
0034680008
-
The conserved PI3'K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila
-
S.E. Scanga, L. Ruel, R.C. Binari, B. Snow, V. Stambolic, D. Bouchard, M. Peters, B. Calvieri, T.W. Mak, J.R. Woodgett, and A.S. Manoukian The conserved PI3'K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila Oncogene 19 2000 3971 3977
-
(2000)
Oncogene
, vol.19
, pp. 3971-3977
-
-
Scanga, S.E.1
Ruel, L.2
Binari, R.C.3
Snow, B.4
Stambolic, V.5
Bouchard, D.6
Peters, M.7
Calvieri, B.8
Mak, T.W.9
Woodgett, J.R.10
Manoukian, A.S.11
-
7
-
-
0142195915
-
Signal transduction: Putting translation before transcription
-
G.C. Prendergast Signal transduction: putting translation before transcription Cancer Cell 4 2003 244 245
-
(2003)
Cancer Cell
, vol.4
, pp. 244-245
-
-
Prendergast, G.C.1
-
8
-
-
2342618936
-
Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression
-
J. Liang, and J.M. Slingerland Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression Cell Cycle 2 2003 339 345
-
(2003)
Cell Cycle
, vol.2
, pp. 339-345
-
-
Liang, J.1
Slingerland, J.M.2
-
9
-
-
0037352170
-
Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: A target for cancer chemotherapy
-
F. Chang, J.T. Lee, P.M. Navolanic, L.S. Steelman, J.G. Shelton, W.L. Blalock, R.A. Franklin, and J.A. McCubrey Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy Leukemia 17 2003 590 603
-
(2003)
Leukemia
, vol.17
, pp. 590-603
-
-
Chang, F.1
Lee, J.T.2
Navolanic, P.M.3
Steelman, L.S.4
Shelton, J.G.5
Blalock, W.L.6
Franklin, R.A.7
McCubrey, J.A.8
-
10
-
-
1642471831
-
PI3K/Akt and apoptosis: Size matters
-
T.F. Franke, C.P. Hornik, L. Segev, G.A. Shostak, and C. Sugimoto PI3K/Akt and apoptosis: size matters Oncogene 22 2003 8983 8998
-
(2003)
Oncogene
, vol.22
, pp. 8983-8998
-
-
Franke, T.F.1
Hornik, C.P.2
Segev, L.3
Shostak, G.A.4
Sugimoto, C.5
-
11
-
-
0034653608
-
The PI3K-PDK1 connection: More than just a road to PKB
-
B. Vanhaesebroeck, and D.R. Alessi The PI3K-PDK1 connection: more than just a road to PKB Biochem. J. 346 Pt. 3 2000 561 576
-
(2000)
Biochem. J.
, vol.346
, Issue.3 PART
, pp. 561-576
-
-
Vanhaesebroeck, B.1
Alessi, D.R.2
-
12
-
-
0035913188
-
Oncogenic transformation induced by membrane-targeted Akt2 and Akt3
-
I. Mende, S. Malstrom, P.N. Tsichlis, P.K. Vogt, and M. Aoki Oncogenic transformation induced by membrane-targeted Akt2 and Akt3 Oncogene 20 2001 4419 4423
-
(2001)
Oncogene
, vol.20
, pp. 4419-4423
-
-
Mende, I.1
Malstrom, S.2
Tsichlis, P.N.3
Vogt, P.K.4
Aoki, M.5
-
13
-
-
15444374951
-
Akt2 phosphorylates Synip to regulate docking and fusion of GLUT4-containing vesicles
-
E. Yamada, S. Okada, T. Saito, K. Ohshima, M. Sato, T. Tsuchiya, Y. Uehara, H. Shimizu, and M. Mori Akt2 phosphorylates Synip to regulate docking and fusion of GLUT4-containing vesicles J. Cell Biol. 168 2005 921 928
-
(2005)
J. Cell Biol.
, vol.168
, pp. 921-928
-
-
Yamada, E.1
Okada, S.2
Saito, T.3
Ohshima, K.4
Sato, M.5
Tsuchiya, T.6
Uehara, Y.7
Shimizu, H.8
Mori, M.9
-
14
-
-
20044382806
-
Role for Akt3/protein kinase Bgamma in attainment of normal brain size
-
R.M. Easton, H. Cho, K. Roovers, D.W. Shineman, M. Mizrahi, M.S. Forman, V.M. Lee, M. Szabolcs, R. de Jong, T. Oltersdorf, T. Ludwig, A. Efstratiadis, and M.J. Birnbaum Role for Akt3/protein kinase Bgamma in attainment of normal brain size Mol. Cell. Biol. 25 2005 1869 1878
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 1869-1878
-
-
Easton, R.M.1
Cho, H.2
Roovers, K.3
Shineman, D.W.4
Mizrahi, M.5
Forman, M.S.6
Lee, V.M.7
Szabolcs, M.8
De Jong, R.9
Oltersdorf, T.10
Ludwig, T.11
Efstratiadis, A.12
Birnbaum, M.J.13
-
15
-
-
0026667730
-
AKT2 a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas
-
J.Q. Cheng, A.K. Godwin, A. Bellacosa, T. Taguchi, T.F. Franke, T.C. Hamilton, P.N. Tsichlis, and J.R. Testa AKT2 a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas Proc. Nat.l Acad. Sci. U. S. A. 89 1992 9267 9271
-
(1992)
Proc. Nat.l Acad. Sci. U. S. A.
, vol.89
, pp. 9267-9271
-
-
Cheng, J.Q.1
Godwin, A.K.2
Bellacosa, A.3
Taguchi, T.4
Franke, T.F.5
Hamilton, T.C.6
Tsichlis, P.N.7
Testa, J.R.8
-
16
-
-
0001457668
-
Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA
-
J.Q. Cheng, B. Ruggeri, W.M. Klein, G. Sonoda, D.A. Altomare, D.K. Watson, and J.R. Testa Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA Proc. Nat.l Acad. Sci. U. S. A. 93 1996 3636 3641
-
(1996)
Proc. Nat.l Acad. Sci. U. S. A.
, vol.93
, pp. 3636-3641
-
-
Cheng, J.Q.1
Ruggeri, B.2
Klein, W.M.3
Sonoda, G.4
Altomare, D.A.5
Watson, D.K.6
Testa, J.R.7
-
17
-
-
0033618371
-
Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines
-
K. Nakatani, D.A. Thompson, A. Barthel, H. Sakaue, W. Liu, R.J. Weigel, and R.A. Roth Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines J. Biol. Chem. 274 1999 21528 21532
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 21528-21532
-
-
Nakatani, K.1
Thompson, D.A.2
Barthel, A.3
Sakaue, H.4
Liu, W.5
Weigel, R.J.6
Roth, R.A.7
-
18
-
-
0038624395
-
Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2
-
X.D. Peng, P.Z. Xu, M.L. Chen, A. Hahn-Windgassen, J. Skeen, J. Jacobs, D. Sundararajan, W.S. Chen, S.E. Crawford, K.G. Coleman, and N. Hay Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2 Genes Dev. 17 2003 1352 1365
-
(2003)
Genes Dev.
, vol.17
, pp. 1352-1365
-
-
Peng, X.D.1
Xu, P.Z.2
Chen, M.L.3
Hahn-Windgassen, A.4
Skeen, J.5
Jacobs, J.6
Sundararajan, D.7
Chen, W.S.8
Crawford, S.E.9
Coleman, K.G.10
Hay, N.11
-
19
-
-
0034652392
-
Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells
-
B.H. Jiang, J.Z. Zheng, M. Aoki, and P.K. Vogt Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells Proc. Nat.l Acad. Sci. U. S. A. 97 2000 1749 1753
-
(2000)
Proc. Nat.l Acad. Sci. U. S. A.
, vol.97
, pp. 1749-1753
-
-
Jiang, B.H.1
Zheng, J.Z.2
Aoki, M.3
Vogt, P.K.4
-
20
-
-
0037188941
-
Role of Akt signaling in vascular homeostasis and angiogenesis
-
I. Shiojima, and K. Walsh Role of Akt signaling in vascular homeostasis and angiogenesis Circ. Res. 90 2002 1243 1250
-
(2002)
Circ. Res.
, vol.90
, pp. 1243-1250
-
-
Shiojima, I.1
Walsh, K.2
-
21
-
-
0034638623
-
Induction of hypoxia-inducible-factor 1 by nitric oxide is mediated via the PI 3K pathway
-
K.B. Sandau, H.G. Faus, and B. Brune Induction of hypoxia-inducible- factor 1 by nitric oxide is mediated via the PI 3K pathway Biochem. Biophys. Res. Commun. 278 2000 263 267
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.278
, pp. 263-267
-
-
Sandau, K.B.1
Faus, H.G.2
Brune, B.3
-
22
-
-
0030869787
-
Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element
-
N.M. Mazure, E.Y. Chen, K.R. Laderoute, and A.J. Giaccia Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element Blood 90 1997 3322 3331
-
(1997)
Blood
, vol.90
, pp. 3322-3331
-
-
Mazure, N.M.1
Chen, E.Y.2
Laderoute, K.R.3
Giaccia, A.J.4
-
23
-
-
0033542476
-
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
-
S. Dimmeler, I. Fleming, B. Fisslthaler, C. Hermann, R. Busse, and A.M. Zeiher Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation Nature 399 1999 601 605
-
(1999)
Nature
, vol.399
, pp. 601-605
-
-
Dimmeler, S.1
Fleming, I.2
Fisslthaler, B.3
Hermann, C.4
Busse, R.5
Zeiher, A.M.6
-
24
-
-
2642597076
-
Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells
-
A. Papapetropoulos, G. Garcia-Cardena, J.A. Madri, and W.C. Sessa Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells J. Clin. Invest. 100 1997 3131 3139
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 3131-3139
-
-
Papapetropoulos, A.1
Garcia-Cardena, G.2
Madri, J.A.3
Sessa, W.C.4
-
26
-
-
17944363486
-
Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis
-
M.J. Lee, S. Thangada, J.H. Paik, G.P. Sapkota, N. Ancellin, S.S. Chae, M. Wu, M. Morales-Ruiz, W.C. Sessa, D.R. Alessi, and T. Hla Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis Mol. Cell 8 2001 693 704
-
(2001)
Mol. Cell
, vol.8
, pp. 693-704
-
-
Lee, M.J.1
Thangada, S.2
Paik, J.H.3
Sapkota, G.P.4
Ancellin, N.5
Chae, S.S.6
Wu, M.7
Morales-Ruiz, M.8
Sessa, W.C.9
Alessi, D.R.10
Hla, T.11
-
27
-
-
0141591547
-
VEGF induces S1P1 receptors in endothelial cells: Implications for cross-talk between sphingolipid and growth factor receptors
-
J. Igarashi, P.A. Erwin, A.P. Dantas, H. Chen, and T. Michel VEGF induces S1P1 receptors in endothelial cells: implications for cross-talk between sphingolipid and growth factor receptors Proc. Nat.l Acad. Sci. U. S. A. 100 2003 10664 10669
-
(2003)
Proc. Nat.l Acad. Sci. U. S. A.
, vol.100
, pp. 10664-10669
-
-
Igarashi, J.1
Erwin, P.A.2
Dantas, A.P.3
Chen, H.4
Michel, T.5
-
28
-
-
0032515047
-
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation
-
H.P. Gerber, A. McMurtrey, J. Kowalski, M. Yan, B.A. Keyt, V. Dixit, and N. Ferrara Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation J. Biol. Chem. 273 1998 30336 30343
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 30336-30343
-
-
Gerber, H.P.1
McMurtrey, A.2
Kowalski, J.3
Yan, M.4
Keyt, B.A.5
Dixit, V.6
Ferrara, N.7
-
29
-
-
0028719263
-
Light scatter of isolated cell nuclei as a parameter discriminating the cell-cycle subcompartments
-
W. Giaretti, and M. Nusse Light scatter of isolated cell nuclei as a parameter discriminating the cell-cycle subcompartments Methods Cell Biol. 41 1994 389 400
-
(1994)
Methods Cell Biol.
, vol.41
, pp. 389-400
-
-
Giaretti, W.1
Nusse, M.2
-
30
-
-
0037162037
-
Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors
-
M.J. Kluk, and T. Hla Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors Biochim. Biophys. Acta 1582 2002 72 80
-
(2002)
Biochim. Biophys. Acta
, vol.1582
, pp. 72-80
-
-
Kluk, M.J.1
Hla, T.2
-
31
-
-
0036783025
-
Transcription and expression of CD44 variant exons by oro-pharyngeal squamous cell carcinomas
-
B.K. Bloor, A. Rajarajan, K. Jaafary-Haghighat, and E.W. Odell Transcription and expression of CD44 variant exons by oro-pharyngeal squamous cell carcinomas Int. J. Oncol. 21 2002 907 913
-
(2002)
Int. J. Oncol.
, vol.21
, pp. 907-913
-
-
Bloor, B.K.1
Rajarajan, A.2
Jaafary-Haghighat, K.3
Odell, E.W.4
-
32
-
-
0037162095
-
Pathways of transduction engaged by sphingosine 1-phosphate through G protein-coupled receptors
-
S. Siehler, and D.R. Manning Pathways of transduction engaged by sphingosine 1-phosphate through G protein-coupled receptors Biochim. Biophys. Acta 1582 2002 94 99
-
(2002)
Biochim. Biophys. Acta
, vol.1582
, pp. 94-99
-
-
Siehler, S.1
Manning, D.R.2
-
34
-
-
0034661482
-
Sphingosine 1-phosphate signalling in mammalian cells
-
S. Pyne, and N.J. Pyne Sphingosine 1-phosphate signalling in mammalian cells Biochem. J. 349 2000 385 402
-
(2000)
Biochem. J.
, vol.349
, pp. 385-402
-
-
Pyne, S.1
Pyne, N.J.2
-
35
-
-
0036239322
-
Cell type-specific localization of human cardiac S1P receptors
-
D. Mazurais, P. Robert, B. Gout, I. Berrebi-Bertrand, M.P. Laville, and T. Calmels Cell type-specific localization of human cardiac S1P receptors J. Histochem. Cytochem. 50 2002 661 670
-
(2002)
J. Histochem. Cytochem.
, vol.50
, pp. 661-670
-
-
Mazurais, D.1
Robert, P.2
Gout, B.3
Berrebi-Bertrand, I.4
Laville, M.P.5
Calmels, T.6
-
36
-
-
0034974903
-
Differential regulation of sphingosine-1-phosphate- and VEGF-induced endothelial cell chemotaxis. Involvement of G(ialpha2)-linked Rho kinase activity
-
F. Liu, A.D. Verin, P. Wang, R. Day, R.P. Wersto, F.J. Chrest, D.K. English, and J.G. Garcia Differential regulation of sphingosine-1-phosphate- and VEGF-induced endothelial cell chemotaxis. Involvement of G(ialpha2)-linked Rho kinase activity Am. J. Respir. Cell Mol. Biol. 24 2001 711 719
-
(2001)
Am. J. Respir. Cell Mol. Biol.
, vol.24
, pp. 711-719
-
-
Liu, F.1
Verin, A.D.2
Wang, P.3
Day, R.4
Wersto, R.P.5
Chrest, F.J.6
English, D.K.7
Garcia, J.G.8
-
37
-
-
0036499890
-
Sphingosine 1-phosphate evokes calcium signals in C2C12 myoblasts via Edg3 and Edg5 receptors
-
E. Meacci, F. Cencetti, L. Formigli, R. Squecco, C. Donati, B. Tiribilli, F. Quercioli, S. Zecchi Orlandini, F. Francini, and P. Bruni Sphingosine 1-phosphate evokes calcium signals in C2C12 myoblasts via Edg3 and Edg5 receptors Biochem. J. 362 2002 349 357
-
(2002)
Biochem. J.
, vol.362
, pp. 349-357
-
-
Meacci, E.1
Cencetti, F.2
Formigli, L.3
Squecco, R.4
Donati, C.5
Tiribilli, B.6
Quercioli, F.7
Zecchi Orlandini, S.8
Francini, F.9
Bruni, P.10
-
38
-
-
3042743988
-
Akt/protein kinase B signaling inhibitor-2 a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt
-
L. Yang, H.C. Dan, M. Sun, Q. Liu, X.M. Sun, R.I. Feldman, A.D. Hamilton, M. Polokoff, S.V. Nicosia, M. Herlyn, S.M. Sebti, and J.Q. Cheng Akt/protein kinase B signaling inhibitor-2 a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt Cancer Res. 64 2004 4394 4399
-
(2004)
Cancer Res.
, vol.64
, pp. 4394-4399
-
-
Yang, L.1
Dan, H.C.2
Sun, M.3
Liu, Q.4
Sun, X.M.5
Feldman, R.I.6
Hamilton, A.D.7
Polokoff, M.8
Nicosia, S.V.9
Herlyn, M.10
Sebti, S.M.11
Cheng, J.Q.12
-
39
-
-
20044375047
-
Activated forms of H-RAS and K-RAS differentially regulate membrane association of PI3K, PDK-1 and AKT and the effect of therapeutic kinase inhibitors on cell survival
-
R.W. Caron, A. Yacoub, M. Li, X. Zhu, C. Mitchell, Y. Hong, W. Hawkins, T. Sasazuki, S. Shirasawa, A.P. Kozikowski, P.A. Dennis, M.P. Hagan, S. Grant, and P. Dent Activated forms of H-RAS and K-RAS differentially regulate membrane association of PI3K, PDK-1 and AKT and the effect of therapeutic kinase inhibitors on cell survival Mol. Cancer Ther. 4 2005 257 270
-
(2005)
Mol. Cancer Ther.
, vol.4
, pp. 257-270
-
-
Caron, R.W.1
Yacoub, A.2
Li, M.3
Zhu, X.4
Mitchell, C.5
Hong, Y.6
Hawkins, W.7
Sasazuki, T.8
Shirasawa, S.9
Kozikowski, A.P.10
Dennis, P.A.11
Hagan, M.P.12
Grant, S.13
Dent, P.14
-
40
-
-
0032491579
-
Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway
-
R.C. Muise-Helmericks, H.L. Grimes, A. Bellacosa, S.E. Malstrom, P.N. Tsichlis, and N. Rosen Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway J. Biol. Chem. 273 1998 29864 29872
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29864-29872
-
-
Muise-Helmericks, R.C.1
Grimes, H.L.2
Bellacosa, A.3
Malstrom, S.E.4
Tsichlis, P.N.5
Rosen, N.6
-
41
-
-
0032533225
-
Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization
-
J.A. Diehl, M. Cheng, M.F. Roussel, and C.J. Sherr Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization Genes Dev. 12 1998 3499 3511
-
(1998)
Genes Dev.
, vol.12
, pp. 3499-3511
-
-
Diehl, J.A.1
Cheng, M.2
Roussel, M.F.3
Sherr, C.J.4
-
42
-
-
0034724736
-
Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt
-
M. Morales-Ruiz, D. Fulton, G. Sowa, L.R. Languino, Y. Fujio, K. Walsh, and W.C. Sessa Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt Circ. Res. 86 2000 892 896
-
(2000)
Circ. Res.
, vol.86
, pp. 892-896
-
-
Morales-Ruiz, M.1
Fulton, D.2
Sowa, G.3
Languino, L.R.4
Fujio, Y.5
Walsh, K.6
Sessa, W.C.7
-
43
-
-
3042702886
-
Akt is a major angiogenic mediator downstream of the Ang1/Tie2 signaling pathway
-
L.M. DeBusk, D.E. Hallahan, and P.C. Lin Akt is a major angiogenic mediator downstream of the Ang1/Tie2 signaling pathway Exp. Cell Res. 298 2004 167 177
-
(2004)
Exp. Cell Res.
, vol.298
, pp. 167-177
-
-
Debusk, L.M.1
Hallahan, D.E.2
Lin, P.C.3
-
44
-
-
0037044854
-
Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitric-oxide synthase (eNOS)
-
T. Tanimoto, Z.G. Jin, and B.C. Berk Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitric-oxide synthase (eNOS) J. Biol. Chem. 277 2002 42997 43001
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42997-43001
-
-
Tanimoto, T.1
Jin, Z.G.2
Berk, B.C.3
-
45
-
-
0037218970
-
Protective role of endothelial nitric oxide synthase
-
E.W. Albrecht, C.A. Stegeman, P. Heeringa, R.H. Henning, and H. van Goor Protective role of endothelial nitric oxide synthase J. Pathol. 99 2003 8 17
-
(2003)
J. Pathol.
, vol.99
, pp. 8-17
-
-
Albrecht, E.W.1
Stegeman, C.A.2
Heeringa, P.3
Henning, R.H.4
Van Goor, H.5
-
46
-
-
0034708601
-
Suppression of heat shock protein-70 by ceramide in heat shock-induced HL-60 cell apoptosis
-
T. Kondo, T. Matsuda, M. Tashima, H. Umehara, N. Domae, K. Yokoyama, T. Uchiyama, and T. Okazaki Suppression of heat shock protein-70 by ceramide in heat shock-induced HL-60 cell apoptosis J. Biol. Chem. 275 2000 8872 8879
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 8872-8879
-
-
Kondo, T.1
Matsuda, T.2
Tashima, M.3
Umehara, H.4
Domae, N.5
Yokoyama, K.6
Uchiyama, T.7
Okazaki, T.8
-
47
-
-
0034489934
-
Posttranscriptional regulation of cyclooxygenase-2 in rat intestinal epithelial cells
-
Z. Zhang, H. Sheng, J. Shao, R.D. Beauchamp, and R.N. DuBois Posttranscriptional regulation of cyclooxygenase-2 in rat intestinal epithelial cells Neoplasia 2 2000 523 530
-
(2000)
Neoplasia
, vol.2
, pp. 523-530
-
-
Zhang, Z.1
Sheng, H.2
Shao, J.3
Beauchamp, R.D.4
Dubois, R.N.5
-
48
-
-
0033957550
-
A conserved AU-rich element in the 3′ untranslated region of bcl-2 mRNA is endowed with a destabilizing function that is involved in bcl-2 down-regulation during apoptosis
-
N. Schiavone, P. Rosini, A. Quattrone, M. Donnini, A. Lapucci, L. Citti, A. Bevilacqua, A. Nicolin, and S. Capaccioli A conserved AU-rich element in the 3′ untranslated region of bcl-2 mRNA is endowed with a destabilizing function that is involved in bcl-2 down-regulation during apoptosis FASEB J. 14 2000 174 184
-
(2000)
FASEB J.
, vol.14
, pp. 174-184
-
-
Schiavone, N.1
Rosini, P.2
Quattrone, A.3
Donnini, M.4
Lapucci, A.5
Citti, L.6
Bevilacqua, A.7
Nicolin, A.8
Capaccioli, S.9
-
49
-
-
0032440723
-
Distinct signal transduction pathways are utilized during the tube formation and survival phases of in vitro angiogenesis
-
N. Ilan, S. Mahooti, and J.A. Madri Distinct signal transduction pathways are utilized during the tube formation and survival phases of in vitro angiogenesis J. Cell Sci. 111 Pt. 24 1998 3621 3631
-
(1998)
J. Cell Sci.
, vol.111
, Issue.24 PART
, pp. 3621-3631
-
-
Ilan, N.1
Mahooti, S.2
Madri, J.A.3
|