메뉴 건너뛰기




Volumn 106, Issue 7, 2011, Pages 794-801

Chromatin regulation in schistosomes and histone modifying enzymes as drug targets

Author keywords

Drug target; Histone deacetylase; Histone modifying enzyme; Inhibitor; Schistosoma mansoni

Indexed keywords

SCHISTOSOMA; SCHISTOSOMA MANSONI;

EID: 82255162175     PISSN: 00740276     EISSN: 16788060     Source Type: Journal    
DOI: 10.1590/S0074-02762011000700003     Document Type: Article
Times cited : (32)

References (61)
  • 2
    • 0034192770 scopus 로고    scopus 로고
    • Anti-malarial effect of histone deacetylation inhibitors and mammalian tumour cytodifferentiating agents
    • Andrews KT, Walduck A, Kelso MJ, Fairlie DP, Saul A, Parsons PG 2000. Anti-malarial effect of histone deacetylation inhibitors and mammalian tumour cytodifferentiating agents. Int J Parasitol 30: 761-768.
    • (2000) Int J Parasitol , vol.30 , pp. 761-768
    • Andrews, K.T.1    Walduck, A.2    Kelso, M.J.3    Fairlie, D.P.4    Saul, A.5    Parsons, P.G.6
  • 4
    • 10944243759 scopus 로고    scopus 로고
    • Curcumin, a novel p300/ CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription
    • Balasubramanyam K, Varier RA, Altaf M, Swaminathan V, Siddappa NB, Ranga U, Kundu TK 2004. Curcumin, a novel p300/ CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. J Biol Chem 279: 51163-51171.
    • (2004) J Biol Chem , vol.279 , pp. 51163-51171
    • Balasubramanyam, K.1    Varier, R.A.2    Altaf, M.3    Swaminathan, V.4    Siddappa, N.B.5    Ranga, U.6    Kundu, T.K.7
  • 5
    • 77950022515 scopus 로고    scopus 로고
    • Imatinib has a fatal impact on morphology, pairing stability and survival of adult Schistosoma mansoni in vitro
    • Beckmann S, Grevelding CG 2010. Imatinib has a fatal impact on morphology, pairing stability and survival of adult Schistosoma mansoni in vitro. Int J Parasitol 40: 521-526.
    • (2010) Int J Parasitol , vol.40 , pp. 521-526
    • Beckmann, S.1    Grevelding, C.G.2
  • 8
    • 33748451151 scopus 로고    scopus 로고
    • Anticancer activities of histone deacetylase inhibitors
    • Bolden JE, Peart MJ, Johnstone RW 2006. Anticancer activities of histone deacetylase inhibitors. Nat Rev Drug Disc 5: 769-784.
    • (2006) Nat Rev Drug Disc , vol.5 , pp. 769-784
    • Bolden, J.E.1    Peart, M.J.2    Johnstone, R.W.3
  • 9
    • 71849111550 scopus 로고    scopus 로고
    • Development and characterization of lysine based tripeptide analogues as inhibitors of Sir2 activity
    • Chakrabarty SP, Ramapanicker R, Mishra R, Chandrasekaran S, Balaram H 2009. Development and characterization of lysine based tripeptide analogues as inhibitors of Sir2 activity. Bioorg Med Chem 17: 8060-8072.
    • (2009) Bioorg Med Chem , vol.17 , pp. 8060-8072
    • Chakrabarty, S.P.1    Ramapanicker, R.2    Mishra, R.3    Chandrasekaran, S.4    Balaram, H.5
  • 12
    • 47049097388 scopus 로고    scopus 로고
    • Histone acetyltransferase inhibitor anacardic acid causes changes in global gene expression during in vitro Plasmodium falciparum development
    • Cui L, Miao J, Furuya T, Fan Q, Li X, Rathod PK, Su XZ, Cui L 2008. Histone acetyltransferase inhibitor anacardic acid causes changes in global gene expression during in vitro Plasmodium falciparum development. Eukaryot Cell 7: 1200-1210.
    • (2008) Eukaryot Cell , vol.7 , pp. 1200-1210
    • Cui, L.1    Miao, J.2    Furuya, T.3    Fan, Q.4    Li, X.5    Rathod, P.K.6    Su, X.Z.7    Cui, L.8
  • 15
    • 79251600508 scopus 로고    scopus 로고
    • Piggy-backing the concept of cancer drugs for schistosomiasis treatment: A tangible perspective
    • Dissous C, Grevelding CG 2011. Piggy-backing the concept of cancer drugs for schistosomiasis treatment: a tangible perspective? Trends Parasitol 27: 59-66.
    • (2011) Trends Parasitol , vol.27 , pp. 59-66
    • Dissous, C.1    Grevelding, C.G.2
  • 17
    • 68749093790 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors induce apoptosis, histone hyperacetylation and up-regulation of gene transcription in Schistosoma mansoni
    • Dubois F, Caby S, Oger F, Cosseau C, Capron M, Grunau C, Dissous C, Pierce RJ 2009. Histone deacetylase inhibitors induce apoptosis, histone hyperacetylation and up-regulation of gene transcription in Schistosoma mansoni. Mol Biochem Parasitol 168: 7-15.
    • (2009) Mol Biochem Parasitol , vol.168 , pp. 7-15
    • Dubois, F.1    Caby, S.2    Oger, F.3    Cosseau, C.4    Capron, M.5    Grunau, C.6    Dissous, C.7    Pierce, R.J.8
  • 19
    • 70449732094 scopus 로고    scopus 로고
    • Artemisinin-based combination therapies: A vital tool in efforts to eliminate malaria
    • Eastman RT, Fidock DA 2009. Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria. Nat Rev Microbiol 7: 864-874.
    • (2009) Nat Rev Microbiol , vol.7 , pp. 864-874
    • Eastman, R.T.1    Fidock, D.A.2
  • 20
    • 0028025029 scopus 로고
    • Drug-resistant schistosomiasis: Resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific
    • Fallon PG, Doenhoff MJ 1994. Drug-resistant schistosomiasis: resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific. Am J Trop Med Hyg 51: 83-88.
    • (1994) Am J Trop Med Hyg , vol.51 , pp. 83-88
    • Fallon, P.G.1    Doenhoff, M.J.2
  • 22
    • 0033887456 scopus 로고    scopus 로고
    • Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins
    • Frye RA 2000. Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. Biochem Biophys Res Commun 273: 793-798.
    • (2000) Biochem Biophys Res Commun , vol.273 , pp. 793-798
    • Frye, R.A.1
  • 23
    • 1842578986 scopus 로고    scopus 로고
    • Molecular evolution of the histone deacetylase family: Functional implications of phylogenetic analysis
    • Gregoretti IV, Lee Y-M, Goodson HV 2004. Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis. J Mol Biol 338: 17-31.
    • (2004) J Mol Biol , vol.338 , pp. 17-31
    • Gregoretti, I.V.1    Lee, Y.-M.2    Goodson, H.V.3
  • 26
    • 84934442211 scopus 로고    scopus 로고
    • Histone deacetylases
    • Horn D 2008. Histone deacetylases. Adv Exp Med Biol 625: 81-86.
    • (2008) Adv Exp Med Biol , vol.625 , pp. 81-86
    • Horn, D.1
  • 27
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jeunwein T, Allis CD 2001. Translating the histone code. Science 293: 1074-1080.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jeunwein, T.1    Allis, C.D.2
  • 28
    • 33646773236 scopus 로고    scopus 로고
    • Voltage-gated calcium channel subunits from platyhelminths: Potential role in praziquantel action
    • Jeziorski MC, Greenberg RM 2006. Voltage-gated calcium channel subunits from platyhelminths: potential role in praziquantel action. Int J Parasitol 36: 623-632.
    • (2006) Int J Parasitol , vol.36 , pp. 623-632
    • Jeziorski, M.C.1    Greenberg, R.M.2
  • 29
    • 42149119013 scopus 로고    scopus 로고
    • Structure function analysis of Leishmania sirtuin: An ensemble of in silico and biochemical studies
    • Kadam RU, Tavares J, Kiran VM, Cordeiro A, Ouaissi A, Roy N 2008. Structure function analysis of Leishmania sirtuin: an ensemble of in silico and biochemical studies. Chem Biol Drug Des 71: 501-506.
    • (2008) Chem Biol Drug Des , vol.71 , pp. 501-506
    • Kadam, R.U.1    Tavares, J.2    Kiran, V.M.3    Cordeiro, A.4    Ouaissi, A.5    Roy, N.6
  • 30
    • 35848955628 scopus 로고    scopus 로고
    • Artemisinins and synthetic trioxolanes in the treatment of helminth infections
    • Keiser J, Utzinger J 2007. Artemisinins and synthetic trioxolanes in the treatment of helminth infections. Curr Opp Inf Dis 20: 605-612.
    • (2007) Curr Opp Inf Dis , vol.20 , pp. 605-612
    • Keiser, J.1    Utzinger, J.2
  • 31
    • 1642460965 scopus 로고    scopus 로고
    • Antimalarial and antileishmanial activities of aroyl-pyrrolylhydroxyamides, a new class of histone deacetylase inhibitors
    • Mai A, Cerbara I, Valente S, Massa S, Walker LA, Tekwani BL 2004. Antimalarial and antileishmanial activities of aroyl-pyrrolylhydroxyamides, a new class of histone deacetylase inhibitors. Antimicrob Agents Chemother 48: 1435-1436.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 1435-1436
    • Mai, A.1    Cerbara, I.2    Valente, S.3    Massa, S.4    Walker, L.A.5    Tekwani, B.L.6
  • 32
    • 78049263263 scopus 로고    scopus 로고
    • Schistosoma mansoni: Antischistosomal activity of the four optical isomers and the two racemates of mefloquine on schistosomula and adult worms in vitro and in vivo
    • Manneck T, Braissant O, Ellis W, Keiser J 2011. Schistosoma mansoni: antischistosomal activity of the four optical isomers and the two racemates of mefloquine on schistosomula and adult worms in vitro and in vivo. Exp Parasitol 127: 260-269.
    • (2011) Exp Parasitol , vol.127 , pp. 260-269
    • Manneck, T.1    Braissant, O.2    Ellis, W.3    Keiser, J.4
  • 33
    • 34347394336 scopus 로고    scopus 로고
    • Mode of action of levamisole and pyrantel, anthelmintic resistance, E153 and Q57
    • Martin RJ, Robertson AP 2007. Mode of action of levamisole and pyrantel, anthelmintic resistance, E153 and Q57. Parasitology 134: 1093-1104.
    • (2007) Parasitology , vol.134 , pp. 1093-1104
    • Martin, R.J.1    Robertson, A.P.2
  • 34
    • 36849009695 scopus 로고    scopus 로고
    • Plasmodium falciparum Sir2: An unusual sirtuin with dual histone deacetylase and ADP-ribosyltransferase activity
    • Merrick CJ, Duraisingh MT 2007. Plasmodium falciparum Sir2: an unusual sirtuin with dual histone deacetylase and ADP-ribosyltransferase activity. Eukaryot Cell 6: 2081-2091.
    • (2007) Eukaryot Cell , vol.6 , pp. 2081-2091
    • Merrick, C.J.1    Duraisingh, M.T.2
  • 35
    • 26244436281 scopus 로고    scopus 로고
    • Evolutionarily conserved and non-conserved cellular localizations and functions of human SIRT proteins
    • Michishita E, Park JY, Burneskis JM, Barrett JC, Horikawa I 2005. Evolutionarily conserved and non-conserved cellular localizations and functions of human SIRT proteins. Mol Biol Cell 16: 4623-4635.
    • (2005) Mol Biol Cell , vol.16 , pp. 4623-4635
    • Michishita, E.1    Park, J.Y.2    Burneskis, J.M.3    Barrett, J.C.4    Horikawa, I.5
  • 37
    • 0032972509 scopus 로고    scopus 로고
    • PSORT: A program for detecting the sorting signals of proteins and predicting their subcellular localization
    • Nakai K, Horton P 1999. PSORT: a program for detecting the sorting signals of proteins and predicting their subcellular localization. Trends Biochem Sci 24: 34-35.
    • (1999) Trends Biochem Sci , vol.24 , pp. 34-35
    • Nakai, K.1    Horton, P.2
  • 38
    • 41649103241 scopus 로고    scopus 로고
    • Structure-activity studies on splitomicin derivatives as sirtuin inhibitors and computational prediction of binding mode
    • Neugebauer RC, Uchiechowska U, Meier R, Hruby H, Valkov V, Verdin E, Sippl W, Jung M 2008. Structure-activity studies on splitomicin derivatives as sirtuin inhibitors and computational prediction of binding mode. J Med Chem 51: 1203-1213.
    • (2008) J Med Chem , vol.51 , pp. 1203-1213
    • Neugebauer, R.C.1    Uchiechowska, U.2    Meier, R.3    Hruby, H.4    Valkov, V.5    Verdin, E.6    Sippl, W.7    Jung, M.8
  • 39
    • 0021932250 scopus 로고
    • Central effects in man of the novel schistosomicidal benzodiazepine meclonazepam
    • O'Boyle C, Lambe R, Darragh A 1985. Central effects in man of the novel schistosomicidal benzodiazepine meclonazepam. Eur J Clin Pharmacol 29: 105-108.
    • (1985) Eur J Clin Pharmacol , vol.29 , pp. 105-108
    • O'Boyle, C.1    Lambe, R.2    Darragh, A.3
  • 44
    • 0021319035 scopus 로고
    • Dichotomy in the tissue origin of schistosome acquired class I and class II major histocompatibility complex antigens
    • Sher A, Sacks DL, Simpson AJ, Singer A 1985. Dichotomy in the tissue origin of schistosome acquired class I and class II major histocompatibility complex antigens. J Exp Med 159: 952-957.
    • (1985) J Exp Med , vol.159 , pp. 952-957
    • Sher, A.1    Sacks, D.L.2    Simpson, A.J.3    Singer, A.4
  • 45
    • 33746329784 scopus 로고    scopus 로고
    • Effect of artemether administered alone or in combination with praziquantel to mice infected with Plasmodium berghei or Schistosoma mansoni or both
    • Shu-Hua X, Utzinger J, Chollet J, Tanner M 2006. Effect of artemether administered alone or in combination with praziquantel to mice infected with Plasmodium berghei or Schistosoma mansoni or both. Int J Parasitol 36: 957-964.
    • (2006) Int J Parasitol , vol.36 , pp. 957-964
    • Shu-Hua, X.1    Utzinger, J.2    Chollet, J.3    Tanner, M.4
  • 46
    • 70549091994 scopus 로고    scopus 로고
    • Computational screening of molecular targets in Plasmodium for novel non-resistant anti-malarial drugs
    • Singh N, Misra K 2009. Computational screening of molecular targets in Plasmodium for novel non-resistant anti-malarial drugs. Bioinformation 3: 255-262.
    • (2009) Bioinformation , vol.3 , pp. 255-262
    • Singh, N.1    Misra, K.2
  • 47
    • 0034051227 scopus 로고    scopus 로고
    • Acetylation of histones and transcription-related factors
    • Sterner DE, Berger SL 2000. Acetylation of histones and transcription-related factors. Microbiol Mol Biol Rev 64: 435-459.
    • (2000) Microbiol Mol Biol Rev , vol.64 , pp. 435-459
    • Sterner, D.E.1    Berger, S.L.2
  • 49
    • 34447121292 scopus 로고    scopus 로고
    • Scriptaid and suberoylanilide hydroxamic acid are histone deacetylase inhibitors with potent anti-Toxoplasma gondii activity in vitro
    • Strobl JS, Cassell M, Mitchell SM, Reilly CM, Lindsay DS 2007. Scriptaid and suberoylanilide hydroxamic acid are histone deacetylase inhibitors with potent anti-Toxoplasma gondii activity in vitro. J Parasitol 93: 694-700.
    • (2007) J Parasitol , vol.93 , pp. 694-700
    • Strobl, J.S.1    Cassell, M.2    Mitchell, S.M.3    Reilly, C.M.4    Lindsay, D.S.5
  • 50
    • 33744539154 scopus 로고    scopus 로고
    • Apoptosis signal-regulating kinase 1 is a direct target of E2F1 and contributes to histone deacetylase inhibitor induced apoptosis through positive feedback regulation of E2F1 apoptotic activity
    • Tan J, Zhuang L, Jiang X, Yang KK, Karuturi KM, Yu Q 2006. Apoptosis signal-regulating kinase 1 is a direct target of E2F1 and contributes to histone deacetylase inhibitor induced apoptosis through positive feedback regulation of E2F1 apoptotic activity. J Biol Chem 281: 10508-10515.
    • (2006) J Biol Chem , vol.281 , pp. 10508-10515
    • Tan, J.1    Zhuang, L.2    Jiang, X.3    Yang, K.K.4    Karuturi, K.M.5    Yu, Q.6
  • 52
    • 65549117790 scopus 로고    scopus 로고
    • The varieties of gene amplification, diversification and hypervariability in the human malaria parasite, Plasmodium falciparum
    • Templeton TJ 2009. The varieties of gene amplification, diversification and hypervariability in the human malaria parasite, Plasmodium falciparum. Mol Biochem Parasitol 166: 109-116.
    • (2009) Mol Biochem Parasitol , vol.166 , pp. 109-116
    • Templeton, T.J.1
  • 53
    • 67650786530 scopus 로고    scopus 로고
    • The Schistosoma japonicum genome reveals features of host-parasite interplay
    • The Schistosoma japonicum Genome Sequencing and Functional Analysis Consortium
    • The Schistosoma japonicum Genome Sequencing and Functional Analysis Consortium 2009. The Schistosoma japonicum genome reveals features of host-parasite interplay. Nature 460: 345-352.
    • (2009) Nature , vol.460 , pp. 345-352
  • 54
    • 61449148342 scopus 로고    scopus 로고
    • The effects of 3-methylclonazepam on Schistosoma mansoni musculature are not mediated by benzodiazepine receptors
    • Thibaut JPB, Monteiro LM, Leite LCC, Menezes MS, Lima LM, Noël F 2009. The effects of 3-methylclonazepam on Schistosoma mansoni musculature are not mediated by benzodiazepine receptors. Eur J Pharmacol 606: 9-16.
    • (2009) Eur J Pharmacol , vol.606 , pp. 9-16
    • Thibaut, J.P.B.1    Monteiro, L.M.2    Leite, L.C.C.3    Menezes, M.S.4    Lima, L.M.5    Noël, F.6
  • 55
    • 41749108415 scopus 로고    scopus 로고
    • Ethnopharmacological uses of Erythrina senegalensis: A comparison of three areas in Mali and a link between traditional knowledge and modern biological science
    • Togola A, Austarheim I, Theïs A, Diallo D, Paulsen BS 2008. Ethnopharmacological uses of Erythrina senegalensis: a comparison of three areas in Mali and a link between traditional knowledge and modern biological science. J Ethnobiol Ethnomed 4: 6
    • (2008) J Ethnobiol Ethnomed , vol.4 , pp. 6
    • Togola, A.1    Austarheim, I.2    Theïs, A.3    Diallo, D.4    Paulsen, B.S.5
  • 57
    • 0036064218 scopus 로고    scopus 로고
    • Comparative study of the effects of artemether and artesunate on juvenile and adult Schistosoma mansoni in experimentally infected mice
    • Utzinger J, Chollet J, Tu ZW, Xiao S, Tanner M 2002. Comparative study of the effects of artemether and artesunate on juvenile and adult Schistosoma mansoni in experimentally infected mice. Trans R Soc Trop Med Hyg 96: 318-323.
    • (2002) Trans R Soc Trop Med Hyg , vol.96 , pp. 318-323
    • Utzinger, J.1    Chollet, J.2    Tu, Z.W.3    Xiao, S.4    Tanner, M.5
  • 58
    • 18844362632 scopus 로고    scopus 로고
    • Stage-specific antileishmanial activity of an inhibitor of Sir2 histone deacetylase
    • Vergnes B, Vanhille L, Ouaissi A, Sereno D 2005. Stage-specific antileishmanial activity of an inhibitor of Sir2 histone deacetylase. Acta Trop 94: 107-115
    • (2005) Acta Trop , vol.94 , pp. 107-115
    • Vergnes, B.1    Vanhille, L.2    Ouaissi, A.3    Sereno, D.4
  • 59
    • 79952262759 scopus 로고    scopus 로고
    • Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy
    • Wagner JM, Hackanson B, Lübbert M, Jung M 2010. Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy. Clin Epigenet 1: 117-136.
    • (2010) Clin Epigenet , vol.1 , pp. 117-136
    • Wagner, J.M.1    Hackanson, B.2    Lübbert, M.3    Jung, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.