Anti-malarial effect of histone deacetylation inhibitors and mammalian tumour cytodifferentiating agents

International Journal for Parasitology

Volumn 30, Issue 6, 2000, Pages 761-768

  Andrews, Kathy T ^c   Walduck, Anna ^a   Kelso, Mike J ^b   Fairlie, David P ^b   Saul, Allan ^a   Parsons, Peter G ^a  

^a ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c Department Hygiene and Medical Microbiology   (Germany)

Author keywords

Anti malarial; Histone deacetylation inhibitor; Plasmodium berghei; Plasmodium falciparum; SBHA

Indexed keywords

APICIDIN; CHLOROQUINE; ENZYME INHIBITOR; HISTONE DEACETYLASE; MEFLOQUINE; MW 2996; PYRIMETHAMINE; TRICHOSTATIN A; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; CYTOSTASIS; DRUG STRUCTURE; IC 50; MAMMAL CELL; MUTATION; NONHUMAN; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PROTEIN TARGETING;

ACETAMIDES; ANIMALS; ANTIMALARIALS; ANTINEOPLASTIC AGENTS; AZACITIDINE; CELL DIFFERENTIATION; DNA METHYLATION; ENZYME INHIBITORS; FEMALE; HEMATINICS; HISTONE DEACETYLASES; HYDROXAMIC ACIDS; MICE; MICE, INBRED BALB C; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM;

MAMMALIA; MURINAE; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PROTOZOA;

EID: 0034192770     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-7519(00)00043-6     Document Type: Article

References (41)

1. Darkin-Rattray S.J., Gurnett A.M., Myers R.W., et al. Apicidin: A novel antiprotozoal agent that inhibits parasite histone deacetylase. Proc. Natl. Acad. Sci. USA. 93:1996;13143-13147.
2. Longhurst H.J., Holder A.A. The histones of Plasmodium falciparum: identification, purification and a possible role in the pathology of malaria. Parasitology. 114:1997;413-419.
3. Creedon K.A., Kaslow D.C., Rathod P.K., Wellems T.E. Identification of a Plasmodium falciparum histone 2A gene. Mol. Biochem. Parasitol. 54:1992;113-116.
4. Bennett B.J., Thompson J., Coppel R.L. Identification of Plasmodium falciparum histone 2B and histone 3 genes. Mol. Biochem. Parasitol. 70:1995;231-233.
5. Longhurst H.J., Holder A.A. The sequence of Plasmodium falciparum histone H3. Mol. Biochem. Parasitol. 69:1995;111-113.
6. Lanzer M., Wetheimer S.P., de Bruin D., Ravetch J.V. Chromatin structure determines the sites of chromosome breakages in Plasmodium falciparum. Nucleic. Acids Res. 22:1994;3099-3103.
7. Cary C., Lamont D., Dalton J.P., Doerig C. Plasmodium falciparum chromatin: nucleosomal organisation and histone-like proteins. Parasitol. Res. 80:1994;255-258.
8. Joshi M.B., Lin D.T., Chiang P.H., Goldman N.D., et al. Molecular cloning and nuclear localization of a histone deacetylase homologue in Plasmodium falciparum. Mol. Biochem. Parasitol. 99:1999;11-19.
9. Riggs M.G., Whittaker R.G., Neumann J.R., Ingram V.M. n-Butyrate causes histone modification in HeLa and Friend erythroleukaemia cells. Nature. 268:1977;462-464.
10. Yoshida M., Kijima M., Akita M., Beppu T. Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A. J. Biol. Chem. 28:1990;17174-17179.
11. Leder A., Leder P. Butyric acid, a potent inducer of erythroid differentiation in cultured erythroleukemic cells. Cell. 5:1975;319-322.
12. Kruh J. Effects of sodium butyrate, a new pharmacological agent, on cells in culture. Mol. Cell Biochem. 42:1982;65-82.
13. Yoshida M., Nomura S., Beppu T. Effects of trichostatins on differentiation of murine erythroleukemia cells. Cancer Res. 47:1987;3688-3691.
14. Breslow R., Jursic B., Yan Z.F., et al. Potent cytodifferentiating agents related to hexamethylenebisacetamide. Proc. Natl. Acad. Sci. USA. 88:1991;5542-5546.
15. Parsons P.G., Hansen C., Fairlie D.P., et al. Tumor selectivity and transcriptional activation by azeleic bishydroxamic acid in human melanocytic cells. Biochem. Pharmacol. 53:1997;1719-1724.
16. Qiu L, Kelso MJ, Hansen C, West ML, Fairlie DP, Parsons PG. Antitumour activity in vitro and in vivo of selective differentiating agents containing hydroxamate. Br J Cancer, in press.
17. Richon V.M., Emiliani S., Verdin E., et al. A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases. Proc. Natl. Acad. Sci. USA. 95:1998;3003-3007.
18. Walliker D., Quakyi I.A., Wellems T.E., et al. Genetic analysis of the human malaria parasite Plasmodium falciparum. Science. 236:1987;1661-1666.
19. Wellems T.E., Oduola A.M.J., Fenton B., Desjardins R., Panton L.J., do Rosario V.E. Chromosome size and variation occurs in cloned Plasmodium falciparum on in vitro cultivation. Rev. Brasil Genet. 11:1988;813-825.
20. Ranford-Cartwright L.C., Taylor J., Umasunthar T., et al. Molecular analysis of recrudescent parasites in a Plasmodium falciparum drug efficacy trial in Gabon. Trans. R. Soc. Trop. Med. Hyg. 91:1997;719-724.
21. Saul A., Prescott N., Smith F., Cheng Q., Walliker D. Evidence of cross-contamination among laboratory lines of Plasmodium berghei. Mol. Biochem. Parasitol. 84:1997;143-147.
22. Trager W., Jensen J.B. Human malaria parasites in continuous culture. Science. 193:1976;673-675.
23. Lambros A., Vanderberg P. Synchronization of Plasmodium falciparum stages in culture. 65:1979;418-420.
24. Lambros A, Vanderberg P. Synchronization of Plasmodium falciparum stages in culture. 1979; 65:418-20.
25. Peel S.A., Merritt S.C., Hendy J., Baric R.S. Derivation of highly mefloquine-resistant lines from Plasmodium falciparum in vitro. Am. J. Trop. Med. Hyg. 48:1993;385-397.
26. Tazi J., Bird A. Alternative chromatin structure of CpG islands. Cell. 60:1990;909-920.
27. Jeppesen P., Turner B.M. The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression. Cell. 74:1993;281-289.
28. O'Neill L.P., Turner B.M. Histone H4 acetylation distinguishes coding regions of the human genome from heterochromatin in a differentiation-dependent but transcription-independent manner. EMBO J. 14:1995;3946-3957.
29. Keohane A.M., O'Neill L.P., Belyaev N.D., Lavender J.S., Turner B.M. X-Inactivation and histone H4 acetylation in embryonic stem cells. Dev. Biol. 180:1996;618-630.
30. Boggs B.A., Connors B., Sobel R.E., Chinault A.C., Allis C.D. Reduced levels of histone H3 acetylation on the inactive X chromosome in human females. Chromosoma. 105:1996;303-309.
31. Hsieh C.-L. Dependence of transcriptional repression on CpG methylation density. Mol. Cell. Biol. 14:1994;5487-5494.
32. Selker E.U. Trichostatin A causes selective loss of DNA methylation in Neurospora. Proc. Natl. Acad. Sci. USA. 95:1998;9430-9435.
33. Nan X., Ng H.H., Johnson C.A., et al. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature. 393:1998;386-389.
34. Chen Z.J., Pikaard C.S. Epigenetic silencing of RNA polymerase I transcription: a role for DNA methylation and histone modification in nucleolar dominance. Genes Dev. 11:1997;2124-2136.
35. Trager W., Robert-Gero M., Lederer E. Antimalarial activity of S-isobutyl adenosine against Plasmodium falciparum in culture. FEBS Lett. 85:1978;264-266.
36. Trager W., Tershakovec M., Chiang P.K., Cantoni G.L. Plasmodium falciparum: Antimalarial activity in culture of sinefungin and other methylation inhibitions. Exp. Parasitol. 50:1980;83-89.
37. Whaun J.M., Miura G.A., Brown N.D., Gordon R.K., Chiang P.K. Antimalarial activity of Neoplanocin A with perturbations in the metabolism of purines, polyamines and S-adenosylmethionine. J. Pharmacol. Exp. Ther. 236:1986;277-283.
38. Whaun J.M., Brown N.D., Chiang P.K. Effects of two methylioadenosine analogues, SIBA and deaza-SIBA, on P. falciparum-infected red cells. Prog. Clin. Biol. Res. 155:1984;143-157.
39. Gommers-Ampt J.H., Borst P. Hypermodified bases in DNA. FASEB J. 9:1995;1034-1042.
40. Gommers-Ampt J., Lutgerink J., Borst P. A novel DNA nucleotide in Trypanosoma brucei only present in the mammalian phase of the life-cycle. Nucl. Acids Res. 19:1991;1745-1751.
41. Gommers-Ampt J.H., ven Leeuwen A.L., de Beer A.L., et al. β-D-glucosyl-hydroxymethyluracil: A novel modified base present in the DNA of the parasitic protozoan T. brucei. Cell. 75:1993;1129-1136.