Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: Role of mitochondrial reactive oxygen species and HIF-1α

Neurobiology of Disease

Volumn 45, Issue 1, 2012, Pages 206-218

  Correia, Sónia C ^a,b   Santos, Renato X ^a,b   Cardoso, Sandra M ^a,c   Santos, Maria S ^a,b   Oliveira, Catarina R ^a,c   Moreira, Paula I ^a,d  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Cyanide; Glucotoxicity; Hypoxia inducible factor 1 ; Mitochondria; Mitochondrial network; Mitochondrial reactive oxygen species; Preconditioning

Indexed keywords

2 METHOXYESTRADIOL; ACETYLCYSTEINE; BRAIN PROTEIN; CASPASE 3; CYANIDE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ERYTHROPOIETIN; GLUCOSE; HYDROGEN PEROXIDE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; REACTIVE OXYGEN METABOLITE; VASCULOTROPIN;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN FUNCTION; BRAIN NERVE CELL; BRAIN TOXICITY; CELL ACTIVATION; CELL LEVEL; CELL LOSS; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE POTENTIAL; CELL PROTECTION; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; GLUCOSE BRAIN LEVEL; GLUCOTOXICITY; INTRACELLULAR SIGNALING; MITOCHONDRION; NERVE CELL NETWORK; NEUROPROTECTION; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN STABILITY; PROTEIN SYNTHESIS; RAT;

ANIMALS; BRAIN; CASPASE 3; CELL LINE; CELLS, CULTURED; ENDOTHELIAL CELLS; GLUCOSE; HYDROGEN PEROXIDE; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NEURONS; NITRIC OXIDE SYNTHASE TYPE III; OXYGEN CONSUMPTION; POTASSIUM CYANIDE; RATS; REACTIVE OXYGEN SPECIES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 81955160758     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2011.08.005     Document Type: Article

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