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Volumn 39, Issue 6, 2011, Pages 1775-1779

In vitro pathological modelling using patient-specific induced pluripotent stem cells: The case of progeria

Author keywords

Aging; Hutchinson Gilford progeria syndrome (HGPS); Induced pluripotent stem cell (IPSC); Lamin A C; Progeria

Indexed keywords

DOUBLE STRANDED DNA; KRUPPEL LIKE FACTOR 4; LAMIN A; LAMIN C; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR SOX2;

EID: 81855198150     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20110659     Document Type: Conference Paper
Times cited : (11)

References (50)
  • 1
    • 33845269544 scopus 로고    scopus 로고
    • Hutchinson-Gilford progeria syndrome: Review of the phenotype
    • Hennekam, R.C. (2006) Hutchinson-Gilford progeria syndrome: review of the phenotype. Am. J. Med. Genet. A 140, 2603-2624
    • (2006) Am. J. Med. Genet. A , vol.140 , pp. 2603-2624
    • Hennekam, R.C.1
  • 3
    • 33750379023 scopus 로고    scopus 로고
    • The laminopathies: The functional architecture of the nucleus and its contribution to disease
    • DOI 10.1146/annurev.genom.7.080505.115732
    • Burke, B. and Stewart, C.L. (2006) The laminopathies: the functional architecture of the nucleus and its contribution to disease. Annu. Rev. Genomics Hum. Genet. 7, 369-405 (Pubitemid 44627935)
    • (2006) Annual Review of Genomics and Human Genetics , vol.7 , pp. 369-405
    • Burke, B.1    Stewart, C.L.2
  • 6
    • 69949144385 scopus 로고    scopus 로고
    • Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A
    • Musich, P.R. and Zou, Y. (2009) Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A. Ageing 1, 28-37
    • (2009) Ageing , vol.1 , pp. 28-37
    • Musich, P.R.1    Zou, Y.2
  • 8
    • 33746883839 scopus 로고    scopus 로고
    • Expression of disease-causing lamin A mutants impairs the formation of DNA repair foci
    • DOI 10.1242/jcs.03009
    • Manju, K., Muralikrishna, B. and Parnaik, V.K. (2006) Expression of disease-causing lamin A mutants impairs the formation of DNA repair foci. J. Cell Sci. 119, 2704-2714 (Pubitemid 44184007)
    • (2006) Journal of Cell Science , vol.119 , Issue.13 , pp. 2704-2714
    • Manju, K.1    Muralikrishna, B.2    Parnaik, V.K.3
  • 9
    • 67349126486 scopus 로고    scopus 로고
    • Telomere length in Hutchinson-Gilford progeria syndrome
    • Decker, M.L., Chavez, E., Vulto, I. and Lansdorp, P.M. (2009) Telomere length in Hutchinson-Gilford progeria syndrome. Mech. Ageing Dev. 130, 377-383
    • (2009) Mech. Ageing Dev. , vol.130 , pp. 377-383
    • Decker, M.L.1    Chavez, E.2    Vulto, I.3    Lansdorp, P.M.4
  • 10
    • 33748993124 scopus 로고    scopus 로고
    • Molecular bases of progeroid syndromes
    • DOI 10.1093/hmg/ddl214
    • Navarro, C.L., Cau, P. and Lévy, N. (2006) Molecular bases of progeroid syndromes. Hum. Mol. Genet. 15 (Suppl. 2), R151-R161 (Pubitemid 44446788)
    • (2006) Human Molecular Genetics , vol.15 , Issue.SUPPL. 2
    • Navarro, C.L.1    Cau, P.2    Levy, N.3
  • 12
    • 69249215282 scopus 로고    scopus 로고
    • Farnesyltransferase inhibitor as anticancer agent
    • Agrawal, A.G. and Somani, R.R. (2009) Farnesyltransferase inhibitor as anticancer agent. Mini Rev. Med. Chem. 9, 638-652
    • (2009) Mini Rev. Med. Chem. , vol.9 , pp. 638-652
    • Agrawal, A.G.1    Somani, R.R.2
  • 16
    • 77956875652 scopus 로고    scopus 로고
    • Defective DSB repair correlates with abnormal nuclear morphology and is improved with FTI treatment in Hutchinson-Gilford progeria syndrome fibroblasts
    • Constantinescu, D., Csoka, A.B., Navara, C.S. and Schatten, G.P. (2010) Defective DSB repair correlates with abnormal nuclear morphology and is improved with FTI treatment in Hutchinson-Gilford progeria syndrome fibroblasts. Exp. Cell Res. 316, 2747-2759
    • (2010) Exp. Cell Res. , vol.316 , pp. 2747-2759
    • Constantinescu, D.1    Csoka, A.B.2    Navara, C.S.3    Schatten, G.P.4
  • 20
    • 43049109229 scopus 로고    scopus 로고
    • Mechanisms of action of bisphosphonates: Similarities and differences and their potential influence on clinical efficacy
    • Russell, R.G., Watts, N.B., Ebetino, F.H. and Rogers, M.J. (2008) Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy. Osteoporosis Int. 19, 733-759
    • (2008) Osteoporosis Int. , vol.19 , pp. 733-759
    • Russell, R.G.1    Watts, N.B.2    Ebetino, F.H.3    Rogers, M.J.4
  • 22
    • 79959776029 scopus 로고    scopus 로고
    • Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells
    • Cao, K., Graziotto, J.J., Blair, C.D., Mazzulli, J.R., Erdos, M.R., Krainc, D. and Collins, F.S. (2011) Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells. Sci. Transl. Med. 3, 89ra58
    • (2011) Sci. Transl. Med. , vol.3
    • Cao, K.1    Graziotto, J.J.2    Blair, C.D.3    Mazzulli, J.R.4    Erdos, M.R.5    Krainc, D.6    Collins, F.S.7
  • 23
    • 25444523734 scopus 로고    scopus 로고
    • Dermal fibroblasts in Hutchinson-Gilford progeria syndrome with the lamin A G608G mutation have dysmorphic nuclei and are hypersensitive to heat stress
    • Paradisi, M., McClintock, D., Boguslavsky, R.L., Pedicelli, C., Worman, H.J. and Djabali, K. (2005) Dermal fibroblasts in Hutchinson-Gilford progeria syndrome with the lamin A G608G mutation have dysmorphic nuclei and are hypersensitive to heat stress. BMC Cell Biol. 6, 27
    • (2005) BMC Cell Biol. , vol.6 , pp. 27
    • Paradisi, M.1    McClintock, D.2    Boguslavsky, R.L.3    Pedicelli, C.4    Worman, H.J.5    Djabali, K.6
  • 24
    • 43149124203 scopus 로고    scopus 로고
    • Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing
    • Scaffidi, P. and Misteli, T. (2008) Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing. Nat. Cell Biol. 10, 452-459
    • (2008) Nat. Cell Biol. , vol.10 , pp. 452-459
    • Scaffidi, P.1    Misteli, T.2
  • 25
    • 58349098943 scopus 로고    scopus 로고
    • Accelerated ageing: From mechanism to therapy through animal models
    • Osorio, F.G., Obaya, A.J., Lopéz-Otin, C. and Freije, J.M. (2009) Accelerated ageing: from mechanism to therapy through animal models. Transgenic Res. 18, 7-15
    • (2009) Transgenic Res. , vol.18 , pp. 7-15
    • Osorio, F.G.1    Obaya, A.J.2    Lopéz-Otin, C.3    Freije, J.M.4
  • 28
    • 78650995671 scopus 로고    scopus 로고
    • A human iPSC model of Hutchinson Gilford progeria reveals vascular smooth muscle and mesenchymal stem cell defects
    • Zhang, J., Lian, Q., Zhu, G., Zhou, F., Sui, L., Tan, C., Mutalif, R.A., Navasankari, R., Zhang, Y., Tse, H.F. et al. (2011) A human iPSC model of Hutchinson Gilford progeria reveals vascular smooth muscle and mesenchymal stem cell defects. Cell Stem Cell 8, 31-45
    • (2011) Cell Stem Cell , vol.8 , pp. 31-45
    • Zhang, J.1    Lian, Q.2    Zhu, G.3    Zhou, F.4    Sui, L.5    Tan, C.6    Mutalif, R.A.7    Navasankari, R.8    Zhang, Y.9    Tse, H.F.10
  • 29
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson, J.A., Itskovitz-Eldor, J., Shapiro, S.S., Waknitz, M.A., Swiergiel, J.J., Marshall, V.S. and Jones, J.M. (1998) Embryonic stem cell lines derived from human blastocysts. Science 282, 1145-1147 (Pubitemid 28516247)
    • (1998) Science , vol.282 , Issue.5391 , pp. 1145-1147
    • Thomson, J.A.1
  • 32
    • 35848937244 scopus 로고    scopus 로고
    • Developmental Study of Fragile X Syndrome Using Human Embryonic Stem Cells Derived from Preimplantation Genetically Diagnosed Embryos
    • DOI 10.1016/j.stem.2007.09.001, PII S1934590907001713
    • Eiges, R., Urbach, A., Malcov, M., Frumkin, T., Schwartz, T., Amit, A., Yaron, Y., Eden, A., Yanuka, O., Benvenisty, N. and Ben-Yosef, D. (2007) Developmental study of fragile X syndrome using human embryonic stem cells derived from preimplantation genetically diagnosed embryos. Cell Stem Cell 1, 568-577 (Pubitemid 350079966)
    • (2007) Cell Stem Cell , vol.1 , Issue.5 , pp. 568-577
    • Eiges, R.1    Urbach, A.2    Malcov, M.3    Frumkin, T.4    Schwartz, T.5    Amit, A.6    Yaron, Y.7    Eden, A.8    Yanuka, O.9    Benvenisty, N.10    Ben-Yosef, D.11
  • 34
    • 36248966518 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
    • DOI 10.1016/j.cell.2007.11.019, PII S0092867407014717
    • Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K. and Yamanaka, S. (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872 (Pubitemid 350138099)
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 35
    • 69249208658 scopus 로고    scopus 로고
    • Pluripotent stem cells and disease modelling
    • Colman, A. and Dreesen, O. (2009) Pluripotent stem cells and disease modelling. Cell Stem Cell 5, 244-247
    • (2009) Cell Stem Cell , vol.5 , pp. 244-247
    • Colman, A.1    Dreesen, O.2
  • 40
    • 80052100421 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cell lines from 3 distinct laminopathies bearing heterogeneous mutations in lamin A/C
    • Ho, J.C., Zhou, T., Lai, W.H., Huang, Y., Chan, Y.C., Li, X., Wong, N.L., Li, Y., Au, K.W., Guo, D. et al. (2011) Generation of induced pluripotent stem cell lines from 3 distinct laminopathies bearing heterogeneous mutations in lamin A/C. Ageing 3, 380-390
    • (2011) Ageing , vol.3 , pp. 380-390
    • Ho, J.C.1    Zhou, T.2    Lai, W.H.3    Huang, Y.4    Chan, Y.C.5    Li, X.6    Wong, N.L.7    Li, Y.8    Au, K.W.9    Guo, D.10
  • 43
    • 55849115999 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated without viral integration
    • Stadtfeld, M., Nagaya, M., Utikal, J., Weir, G. and Hochedlinger, K. (2008) Induced pluripotent stem cells generated without viral integration. Science 322, 945-949
    • (2008) Science , vol.322 , pp. 945-949
    • Stadtfeld, M.1    Nagaya, M.2    Utikal, J.3    Weir, G.4    Hochedlinger, K.5
  • 45
    • 77958536106 scopus 로고    scopus 로고
    • Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA
    • Warren, L., Manos, P.D., Ahfeldt, T., Loh, Y.H., Li, H., Lau, F., Ebina, W., Mandal, P.K., Smith, Z.D., Meissner, A. et al. (2010) Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 7, 618-630
    • (2010) Cell Stem Cell , vol.7 , pp. 618-630
    • Warren, L.1    Manos, P.D.2    Ahfeldt, T.3    Loh, Y.H.4    Li, H.5    Lau, F.6    Ebina, W.7    Mandal, P.K.8    Smith, Z.D.9    Meissner, A.10
  • 46
    • 65649116572 scopus 로고    scopus 로고
    • Human induced pluripotent stem cells free of vector and transgene sequences
    • Yu, J., Hu, K., Smuga-Otto, K., Tian, S., Stewart, R., Slukvin, II and Thomson, J.A. (2009) Human induced pluripotent stem cells free of vector and transgene sequences. Science 324, 797-801
    • (2009) Science , vol.324 , pp. 797-801
    • Yu, J.1    Hu, K.2    Smuga-Otto, K.3    Tian, S.4    Stewart, R.5    Slukvin, I.I.6    Thomson, J.A.7
  • 50
    • 33646745137 scopus 로고    scopus 로고
    • Lamin A-dependent nuclear defects in human ageing
    • Scaffidi, P. and Misteli, T. (2006) Lamin A-dependent nuclear defects in human ageing. Science 312, 1059-1063
    • (2006) Science , vol.312 , pp. 1059-1063
    • Scaffidi, P.1    Misteli, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.