Metabolic bioactivation of oestradiol-17β (E2β) in mouse colon epithelial cells bearing ApcMin mutation

Steroids

Volumn 75, Issue 10, 2010, Pages 665-675

  Bellocq, Delphine ^a   Molina, Jérôme ^a   Rathahao Paris, Estelle ^b   Taché, Sylviane ^a   Pierre, Fabrice ^a   Paris, Alain ^a,c  

^a CEMAGREF   (France)

^b AGROPARISTECH   (France)

^c AgrParisTech   (France)

Author keywords

Apc; Catechol oestrogens; Colon carcinogenesis; CYP1A; Min mutation; Oestradiol 17 (E2 )

Indexed keywords

2 CATECHOL ESTROGEN DERIVATIVE; 2 O METHYL ETHER ESTROGEN; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; APC PROTEIN; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; ESTRADIOL; ESTRADIOL 17BETA 3 GLUCURONIDE; MESSENGER RNA; UNCLASSIFIED DRUG; CATECHOL; CATECHOL DERIVATIVE; CYP1B1 PROTEIN, HUMAN; CYP1B1 PROTEIN, MOUSE; UNSPECIFIC MONOOXYGENASE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; COLON MUCOSA; DRUG MECHANISM; GENE MUTATION; INTESTINE EPITHELIUM CELL; MOUSE; NONHUMAN; REVIEW; ANIMAL; CELL LINE; CELL SURVIVAL; COLON; CYTOLOGY; DRUG EFFECTS; EPITHELIUM CELL; GENETICS; MASS SPECTROMETRY; METABOLISM; MUTATION; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CATECHOLS; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; COLON; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 CYP1B1; EPITHELIAL CELLS; ESTRADIOL; MASS SPECTROMETRY; MICE; MUTATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TETRACHLORODIBENZODIOXIN;

EID: 77954314231     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2010.04.003     Document Type: Article

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