Activation of Bmp2-Smad1 signal and its regulation by coordinated alteration of H3K27 trimethylation in Ras-induced senescence

PLoS Genetics

Volumn 7, Issue 11, 2011, Pages

  Kaneda, Atsushi ^a,b   Fujita, Takanori ^a   Anai, Motonobu ^c   Yamamoto, Shogo ^a   Nagae, Genta ^a   Morikawa, Masato ^a   Tsuji, Shingo ^a   Oshima, Masanobu ^d   Miyazono, Kohei ^a   Aburatani, Hiroyuki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; HISTONE H3; POLYCOMB GROUP PROTEIN; RAS PROTEIN; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT PROTEIN; SMAD1 PROTEIN; SMAD4 PROTEIN; SMAD8 PROTEIN; ACTININ; BMP2 PROTEIN, MOUSE; CARRIER PROTEIN; EZH2 PROTEIN, MOUSE; HISTONE LYSINE METHYLTRANSFERASE; NOGGIN PROTEIN; PARVB PROTEIN, MOUSE; SMAD1 PROTEIN, MOUSE; SMAD6 PROTEIN; SMAD6 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; DNA METHYLATION; EMBRYO; EPIGENETICS; GENE INDUCTION; GENE REPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; GENOME; GROWTH INHIBITION; HISTONE METHYLATION; IMMUNOPRECIPITATION; MICROARRAY ANALYSIS; MOUSE; NEGATIVE FEEDBACK; NOGGIN GENE; NONHUMAN; PROTEIN PHOSPHORYLATION; SENESCENCE; SMAD6 GENE; UPREGULATION; ANIMAL; C57BL MOUSE; CELL AGING; CYTOLOGY; FIBROBLAST; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; HUMAN; METABOLISM; ONCOGENE RAS; SIGNAL TRANSDUCTION;

ACTININ; ANIMALS; BONE MORPHOGENETIC PROTEIN 2; CARRIER PROTEINS; CELL AGING; DNA METHYLATION; EPIGENESIS, GENETIC; FIBROBLASTS; GENE EXPRESSION REGULATION; GENES, RAS; GENOME; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; MICE; MICE, INBRED C57BL; SIGNAL TRANSDUCTION; SMAD1 PROTEIN; SMAD6 PROTEIN;

EID: 81755163044     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002359     Document Type: Article

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