Matched molecular pairs as a medicinal chemistry tool

Journal of Medicinal Chemistry

Volumn 54, Issue 22, 2011, Pages 7739-7750

  Griffen, Ed ^a   Leach, Andrew G ^a   Robb, Graeme R ^a   Warner, Daniel J ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYL SULFONE; EPIDERMAL GROWTH FACTOR RECEPTOR; PHENYL GROUP; QUINAZOLINE;

ALGORITHM; ANALYTIC METHOD; CHEMICAL STRUCTURE; ENZYME INHIBITION; ENZYME MECHANISM; IC 50; MATCHED MOLECULAR PAIR ANALYSIS; REVIEW; SOLUBILITY; STRUCTURE ACTIVITY RELATION;

DATABASES, FACTUAL; DRUG DESIGN; MOLECULAR STRUCTURE; PROTEIN KINASE INHIBITORS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 81555204763     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm200452d     Document Type: Review

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