Chemical substitutions that introduce activity cliffs across different compound classes and biological targets

Journal of Chemical Information and Modeling

Volumn 50, Issue 7, 2010, Pages 1248-1256

  Wassermann, Anne Mai ^a   Bajorath, Jürgen ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ANALYSIS; CHEMICAL REACTIONS; SCAFFOLDS;

BIOLOGICAL TARGETS; CHEMICAL CHANGE; CHEMICAL SUBSTITUTION; CHEMICAL TRANSFORMATIONS; MOLECULAR PAIRS; NON-REDUNDANT; PUBLIC DOMAINS;

LANDFORMS;

INTERSTITIAL COLLAGENASE; LIGAND;

ARTICLE; BIOLOGICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; CLASSIFICATION; DRUG DELIVERY SYSTEM; STRUCTURE ACTIVITY RELATION;

DRUG DELIVERY SYSTEMS; LIGANDS; MATRIX METALLOPROTEINASE 1; MODELS, BIOLOGICAL; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78049415439     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci1001845     Document Type: Article

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