The anticancer plant triterpenoid, avicin d, regulates glucocorticoid receptor signaling: Implications for cellular metabolism

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Haridas, Valsala ^a   Xu, Zhi Xiang ^a   Kitchen, Doug ^b   Jiang, Anna ^a   Michels, Peter ^b   Gutterman, Jordan U ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b ALBANY MOLECULAR RESEARCH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; AVICIN D; DEXAMETHASONE; FATTY ACID SYNTHASE; GLUCOCORTICOID RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); TRITERPENOID; UNCLASSIFIED DRUG; DNA; FASN PROTEIN, HUMAN; SAPONIN; TRITERPENE; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; BINDING COMPETITION; CANCER CELL; CELL KILLING; CELL METABOLISM; CONTROLLED STUDY; DELETION MUTANT; DRUG COMPETITION; DRUG DNA BINDING; DRUG RECEPTOR BINDING; DRUG STRUCTURE; EMBRYO; GENE ACTIVATION; GENE REPRESSION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LIGAND BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; STRUCTURE ACTIVITY RELATION; TRANSACTIVATION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; TRANSREPRESSION; BIOLOGICAL MODEL; CELL NUCLEUS; CELLS; CHEMISTRY; DNA RESPONSIVE ELEMENT; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE, TUMOR; CELL NUCLEUS; CELLS; DNA; FATTY ACID SYNTHETASE COMPLEX, TYPE I; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MODELS, BIOLOGICAL; NF-KAPPA B; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECEPTORS, GLUCOCORTICOID; RESPONSE ELEMENTS; SAPONINS; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION; TRITERPENES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 81455133437     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028037     Document Type: Article

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