Parthenolide attenuates LPS-induced fever, circulating cytokines and markers of brain inflammation in rats

Cytokine

Volumn 56, Issue 3, 2011, Pages 739-748

  Rummel, Christoph ^a   Gerstberger, Rüdiger ^a   Roth, Joachim ^a   Hübschle, Thomas ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Circumventricular organs; Cyclooxygenase 2; Immune to brain communication; Nuclear factor kappa B; Systemic inflammation

Indexed keywords

CYCLOOXYGENASE 2; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MESSENGER RNA; NUCLEAR FACTOR INTERLEUKIN 6; PARTHENOLIDE; PROSTAGLANDIN; PROTEIN SERINE THREONINE KINASE; STAT3 PROTEIN; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOGENESIS; BLOOD BRAIN BARRIER; BRAIN MITOCHONDRION; CELL CULTURE; CONTROLLED STUDY; DISEASE MARKER; DRUG EFFECT; ENCEPHALITIS; ENZYME ACTIVITY; FEVER; GENE EXPRESSION REGULATION; GLIA CELL; HYPOTHALAMUS; HYPOTHERMIA; IMMUNOREACTIVITY; MALE; MITOCHONDRIAL TRANSCRIPTION FACTOR A GENE; NONHUMAN; NUCLEAR RESPIRATORY FACTOR 1 GENE; OXIDATIVE STRESS; PERIXOSOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 ALPHA GENE; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN FUNCTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REGULATOR GENE; SIGNAL TRANSDUCTION;

ANIMALS; BIOLOGICAL MARKERS; BODY TEMPERATURE; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELLS, CULTURED; CYTOKINES; ENCEPHALITIS; FEVER; GENE EXPRESSION REGULATION; HYPOTHALAMUS; INJECTIONS, INTRAPERITONEAL; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MALE; MITOCHONDRIA; NF-KAPPA B; OXIDATIVE STRESS; RATS; RATS, WISTAR; RNA, MESSENGER; SESQUITERPENES; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; RATTUS;

EID: 81455131483     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2011.09.022     Document Type: Article

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