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Volumn 33, Issue 6, 2006, Pages 299-308

Parthenolide has limited effects on nuclear factor-κβ increases and worsens survival in lipopolysaccharide-challenged C57BL/6J mice

Author keywords

Anti inflammatory agent; Lipopolysaccharide; Signaling molecules; Treatment

Indexed keywords

CYTOKINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MIGRATION INHIBITION FACTOR; PARTHENOLIDE; PLACEBO; RANTES; TUMOR NECROSIS FACTOR ALPHA;

EID: 33744533883     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2006.03.002     Document Type: Article
Times cited : (22)

References (36)
  • 1
    • 23444446083 scopus 로고
    • Selected treatment strategies for septic shock based on proposed mechanisms of pathogenesis
    • Natanson C., Hoffman W.D., Suffredini A.F., Eichacker P.Q., and Danner R.L. Selected treatment strategies for septic shock based on proposed mechanisms of pathogenesis. Ann Intern Med 120 (1994) 771-783
    • (1994) Ann Intern Med , vol.120 , pp. 771-783
    • Natanson, C.1    Hoffman, W.D.2    Suffredini, A.F.3    Eichacker, P.Q.4    Danner, R.L.5
  • 2
    • 0032541661 scopus 로고    scopus 로고
    • Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling
    • Yang R.B., Mark M.R., Gray A., Huang A., Xie M.H., Zhang M., et al. Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling. Nature 395 (1998) 284-288
    • (1998) Nature , vol.395 , pp. 284-288
    • Yang, R.B.1    Mark, M.R.2    Gray, A.3    Huang, A.4    Xie, M.H.5    Zhang, M.6
  • 3
    • 0031774181 scopus 로고    scopus 로고
    • Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide
    • Kirschning C.J., Wesche H., Merrill Ayres T., and Rothe M. Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide. J Exp Med 188 (1998) 2091-2097
    • (1998) J Exp Med , vol.188 , pp. 2091-2097
    • Kirschning, C.J.1    Wesche, H.2    Merrill Ayres, T.3    Rothe, M.4
  • 4
    • 0033120081 scopus 로고    scopus 로고
    • Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product
    • Hoshino K., Takeuchi O., Kawai T., Sanjo H., Ogawa T., Takeda Y., et al. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J Immunol 162 (1999) 3749-3752
    • (1999) J Immunol , vol.162 , pp. 3749-3752
    • Hoshino, K.1    Takeuchi, O.2    Kawai, T.3    Sanjo, H.4    Ogawa, T.5    Takeda, Y.6
  • 5
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and I kappa B proteins: new discoveries and insights
    • Baldwin Jr. A.S. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol 14 (1996) 649-683
    • (1996) Annu Rev Immunol , vol.14 , pp. 649-683
    • Baldwin Jr., A.S.1
  • 7
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-kappaB transcription factors
    • Pahl H.L. Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 18 (1999) 6853-6866
    • (1999) Oncogene , vol.18 , pp. 6853-6866
    • Pahl, H.L.1
  • 9
    • 0031755148 scopus 로고    scopus 로고
    • Nuclear factor kappa B: a pivotal role in the systemic inflammatory response syndrome and new target for therapy
    • Christman J.W., Lancaster L.H., and Blackwell T.S. Nuclear factor kappa B: a pivotal role in the systemic inflammatory response syndrome and new target for therapy. Intensive Care Med 24 (1998) 1131-1138
    • (1998) Intensive Care Med , vol.24 , pp. 1131-1138
    • Christman, J.W.1    Lancaster, L.H.2    Blackwell, T.S.3
  • 10
    • 0343765810 scopus 로고    scopus 로고
    • Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF-kappaB
    • Bork P.M., Schmitz M.L., Kuhnt M., Escher C., and Heinrich M. Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF-kappaB. FEBS Lett 402 (1997) 85-90
    • (1997) FEBS Lett , vol.402 , pp. 85-90
    • Bork, P.M.1    Schmitz, M.L.2    Kuhnt, M.3    Escher, C.4    Heinrich, M.5
  • 11
    • 0034879173 scopus 로고    scopus 로고
    • The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase
    • Kwok B.H., Koh B., Ndubuisi M.I., Elofsson M., and Crews C.M. The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase. Chem Biol 8 (2001) 759-766
    • (2001) Chem Biol , vol.8 , pp. 759-766
    • Kwok, B.H.1    Koh, B.2    Ndubuisi, M.I.3    Elofsson, M.4    Crews, C.M.5
  • 12
    • 0001112989 scopus 로고    scopus 로고
    • The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-kappaB by directly targeting p65
    • Lyss G., Knorre A., Schmidt T.J., Pahl H.L., and Merfort I. The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-kappaB by directly targeting p65. J Biol Chem 273 (1998) 33508-33516
    • (1998) J Biol Chem , vol.273 , pp. 33508-33516
    • Lyss, G.1    Knorre, A.2    Schmidt, T.J.3    Pahl, H.L.4    Merfort, I.5
  • 13
    • 2942618506 scopus 로고    scopus 로고
    • Role of cysteine residues of p65/NF-kappaB on the inhibition by the sesquiterpene lactone parthenolide and N-ethyl maleimide, and on its transactivating potential
    • Garcia-Pineres A.J., Lindenmeyer M.T., and Merfort I. Role of cysteine residues of p65/NF-kappaB on the inhibition by the sesquiterpene lactone parthenolide and N-ethyl maleimide, and on its transactivating potential. Life Sci 75 (2004) 841-856
    • (2004) Life Sci , vol.75 , pp. 841-856
    • Garcia-Pineres, A.J.1    Lindenmeyer, M.T.2    Merfort, I.3
  • 14
    • 0033571108 scopus 로고    scopus 로고
    • The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-kappa B by targeting the I kappa B kinase complex
    • Hehner S.P., Hofmann T.G., Droge W., and Schmitz M.L. The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-kappa B by targeting the I kappa B kinase complex. J Immunol 163 (1999) 5617-5623
    • (1999) J Immunol , vol.163 , pp. 5617-5623
    • Hehner, S.P.1    Hofmann, T.G.2    Droge, W.3    Schmitz, M.L.4
  • 15
    • 0033949765 scopus 로고    scopus 로고
    • Sesquiterpene lactones are potent inhibitors of interleukin 8 gene expression in cultured human respiratory epithelium
    • Mazor R.L., Menendez I.Y., Ryan M.A., Fiedler M.A., and Wong H.R. Sesquiterpene lactones are potent inhibitors of interleukin 8 gene expression in cultured human respiratory epithelium. Cytokine 12 (2000) 239-245
    • (2000) Cytokine , vol.12 , pp. 239-245
    • Mazor, R.L.1    Menendez, I.Y.2    Ryan, M.A.3    Fiedler, M.A.4    Wong, H.R.5
  • 16
    • 0031915368 scopus 로고    scopus 로고
    • Sesquiterpene lactones specifically inhibit activation of NF-kappa B by preventing the degradation of I kappa B-alpha and I kappa B-beta
    • Hehner S.P., Heinrich M., Bork P.M., Vogt M., Ratter F., Lehmann V., et al. Sesquiterpene lactones specifically inhibit activation of NF-kappa B by preventing the degradation of I kappa B-alpha and I kappa B-beta. J Biol Chem 273 (1998) 1288-1297
    • (1998) J Biol Chem , vol.273 , pp. 1288-1297
    • Hehner, S.P.1    Heinrich, M.2    Bork, P.M.3    Vogt, M.4    Ratter, F.5    Lehmann, V.6
  • 17
    • 0036677151 scopus 로고    scopus 로고
    • The sesquiterpene lactone parthenolide inhibits LPS- but not TNF-alpha-induced maturation of human monocyte-derived dendritic cells by inhibition of the p38 mitogen-activated protein kinase pathway
    • Uchi H., Arrighi J.F., Aubry J.P., Furue M., and Hauser C. The sesquiterpene lactone parthenolide inhibits LPS- but not TNF-alpha-induced maturation of human monocyte-derived dendritic cells by inhibition of the p38 mitogen-activated protein kinase pathway. J Allergy Clin Immunol 110 (2002) 269-276
    • (2002) J Allergy Clin Immunol , vol.110 , pp. 269-276
    • Uchi, H.1    Arrighi, J.F.2    Aubry, J.P.3    Furue, M.4    Hauser, C.5
  • 18
    • 0036237368 scopus 로고    scopus 로고
    • Parthenolide, an inhibitor of the nuclear factor-kappaB pathway, ameliorates cardiovascular derangement and outcome in endotoxic shock in rodents
    • Sheehan M., Wong H.R., Hake P.W., Malhotra V., O'Connor M., and Zingarelli B. Parthenolide, an inhibitor of the nuclear factor-kappaB pathway, ameliorates cardiovascular derangement and outcome in endotoxic shock in rodents. Mol Pharmacol 61 (2002) 953-963
    • (2002) Mol Pharmacol , vol.61 , pp. 953-963
    • Sheehan, M.1    Wong, H.R.2    Hake, P.W.3    Malhotra, V.4    O'Connor, M.5    Zingarelli, B.6
  • 19
    • 0036114224 scopus 로고    scopus 로고
    • Protective effects of isohelenin, an inhibitor of nuclear factor kappaB, in endotoxic shock in rats
    • Sheehan M., Wong H.R., Hake P.W., and Zingarelli B. Protective effects of isohelenin, an inhibitor of nuclear factor kappaB, in endotoxic shock in rats. J Endotoxin Res 8 (2002) 99-107
    • (2002) J Endotoxin Res , vol.8 , pp. 99-107
    • Sheehan, M.1    Wong, H.R.2    Hake, P.W.3    Zingarelli, B.4
  • 20
    • 0042140583 scopus 로고    scopus 로고
    • Parthenolide improves systemic hemodynamics and decreases tissue leukosequestration in rats with polymicrobial sepsis
    • Sheehan M., Wong H.R., Hake P.W., and Zingarelli B. Parthenolide improves systemic hemodynamics and decreases tissue leukosequestration in rats with polymicrobial sepsis. Crit Care Med 31 (2003) 2263-2270
    • (2003) Crit Care Med , vol.31 , pp. 2263-2270
    • Sheehan, M.1    Wong, H.R.2    Hake, P.W.3    Zingarelli, B.4
  • 21
    • 0031572429 scopus 로고    scopus 로고
    • In vivo inhibition of nuclear factor-kappa B activation prevents inducible nitric oxide synthase expression and systemic hypotension in a rat model of septic shock
    • Liu S.F., Ye X., and Malik A.B. In vivo inhibition of nuclear factor-kappa B activation prevents inducible nitric oxide synthase expression and systemic hypotension in a rat model of septic shock. J Immunol 159 (1997) 3976-3983
    • (1997) J Immunol , vol.159 , pp. 3976-3983
    • Liu, S.F.1    Ye, X.2    Malik, A.B.3
  • 22
    • 1842640502 scopus 로고    scopus 로고
    • Molecular mechanisms of the effect of herpesvirus saimiri protein StpC on the signaling pathway leading to NF-kappaB activation
    • Sorokina E.M., Merlo Jr. J.J., and Tsygankov A.Y. Molecular mechanisms of the effect of herpesvirus saimiri protein StpC on the signaling pathway leading to NF-kappaB activation. J Biol Chem 279 (2004) 13469-13477
    • (2004) J Biol Chem , vol.279 , pp. 13469-13477
    • Sorokina, E.M.1    Merlo Jr., J.J.2    Tsygankov, A.Y.3
  • 23
    • 0036848107 scopus 로고    scopus 로고
    • Inhibition of LPS-induced p42/44 MAP kinase activation and iNOS/NO synthesis by parthenolide in rat primary microglial cells
    • Fiebich B.L., Lieb K., Engels S., and Heinrich M. Inhibition of LPS-induced p42/44 MAP kinase activation and iNOS/NO synthesis by parthenolide in rat primary microglial cells. J Neuroimmunol 132 (2002) 18-24
    • (2002) J Neuroimmunol , vol.132 , pp. 18-24
    • Fiebich, B.L.1    Lieb, K.2    Engels, S.3    Heinrich, M.4
  • 24
    • 16644376048 scopus 로고    scopus 로고
    • Sesquiterpene lactone parthenolide blocks lipopolysaccharide-induced osteolysis through the suppression of NF-kappaB activity
    • Yip K.H., Zheng M.H., Feng H.T., Steer J.H., Joyce D.A., and Xu J. Sesquiterpene lactone parthenolide blocks lipopolysaccharide-induced osteolysis through the suppression of NF-kappaB activity. J Bone Miner Res 19 (2004) 1905-1916
    • (2004) J Bone Miner Res , vol.19 , pp. 1905-1916
    • Yip, K.H.1    Zheng, M.H.2    Feng, H.T.3    Steer, J.H.4    Joyce, D.A.5    Xu, J.6
  • 25
    • 0033610023 scopus 로고    scopus 로고
    • Sesquiterpene lactones inhibit inducible nitric oxide synthase gene expression in cultured rat aortic smooth muscle cells
    • Wong H.R., and Menendez I.Y. Sesquiterpene lactones inhibit inducible nitric oxide synthase gene expression in cultured rat aortic smooth muscle cells. Biochem Biophys Res Commun 262 (1999) 375-380
    • (1999) Biochem Biophys Res Commun , vol.262 , pp. 375-380
    • Wong, H.R.1    Menendez, I.Y.2
  • 26
    • 0030600363 scopus 로고    scopus 로고
    • Inhibition of the expression of inducible cyclooxygenase and proinflammatory cytokines by sesquiterpene lactones in macrophages correlates with the inhibition of MAP kinases
    • Hwang D., Fischer N.H., Jang B.C., Tak H., Kim J.K., and Lee W. Inhibition of the expression of inducible cyclooxygenase and proinflammatory cytokines by sesquiterpene lactones in macrophages correlates with the inhibition of MAP kinases. Biochem Biophys Res Commun 226 (1996) 810-818
    • (1996) Biochem Biophys Res Commun , vol.226 , pp. 810-818
    • Hwang, D.1    Fischer, N.H.2    Jang, B.C.3    Tak, H.4    Kim, J.K.5    Lee, W.6
  • 27
    • 0141655182 scopus 로고    scopus 로고
    • Modulation of lipopolysaccharide-induced proinflammatory cytokine production in vitro and in vivo by the herbal constituents apigenin (chamomile), ginsenoside Rb(1) (ginseng) and parthenolide (feverfew)
    • Smolinski A.T., and Pestka J.J. Modulation of lipopolysaccharide-induced proinflammatory cytokine production in vitro and in vivo by the herbal constituents apigenin (chamomile), ginsenoside Rb(1) (ginseng) and parthenolide (feverfew). Food Chem Toxicol 41 (2003) 1381-1390
    • (2003) Food Chem Toxicol , vol.41 , pp. 1381-1390
    • Smolinski, A.T.1    Pestka, J.J.2
  • 28
    • 0034021896 scopus 로고    scopus 로고
    • Predictive value of nuclear factor kappaB activity and plasma cytokine levels in patients with sepsis
    • Arnalich F., Garcia-Palomero E., Lopez J., Jimenez M., Madero R., Renart J., et al. Predictive value of nuclear factor kappaB activity and plasma cytokine levels in patients with sepsis. Infect Immun 68 (2000) 1942-1945
    • (2000) Infect Immun , vol.68 , pp. 1942-1945
    • Arnalich, F.1    Garcia-Palomero, E.2    Lopez, J.3    Jimenez, M.4    Madero, R.5    Renart, J.6
  • 29
    • 0028898380 scopus 로고
    • Persistent elevation of inflammatory cytokines predicts a poor outcome in ARDS. Plasma IL-1 beta and IL-6 levels are consistent and efficient predictors of outcome over time
    • Meduri G.U., Headley S., Kohler G., Stentz F., Tolley E., Umberger R., et al. Persistent elevation of inflammatory cytokines predicts a poor outcome in ARDS. Plasma IL-1 beta and IL-6 levels are consistent and efficient predictors of outcome over time. Chest 107 (1995) 1062-1073
    • (1995) Chest , vol.107 , pp. 1062-1073
    • Meduri, G.U.1    Headley, S.2    Kohler, G.3    Stentz, F.4    Tolley, E.5    Umberger, R.6
  • 30
    • 0036281071 scopus 로고    scopus 로고
    • Differential susceptibility to acute Trypanosoma cruzi infection in BALB/c and C57BL/6 mice is not associated with a distinct parasite load but cytokine abnormalities
    • Roggero E., Perez A., Tamae-Kakazu M., Piazzon I., Nepomnaschy I., Wietzerbin J., et al. Differential susceptibility to acute Trypanosoma cruzi infection in BALB/c and C57BL/6 mice is not associated with a distinct parasite load but cytokine abnormalities. Clin Exp Immunol 128 (2002) 421-428
    • (2002) Clin Exp Immunol , vol.128 , pp. 421-428
    • Roggero, E.1    Perez, A.2    Tamae-Kakazu, M.3    Piazzon, I.4    Nepomnaschy, I.5    Wietzerbin, J.6
  • 31
    • 17344364816 scopus 로고    scopus 로고
    • Strain difference in the induction of T-cell activation-associated, interferon gamma-dependent hepatic injury in mice
    • Mizuhara H., Kuno M., Seki N., Yu W.G., Yamaoka M., Yamashita M., et al. Strain difference in the induction of T-cell activation-associated, interferon gamma-dependent hepatic injury in mice. Hepatology 27 (1998) 513-519
    • (1998) Hepatology , vol.27 , pp. 513-519
    • Mizuhara, H.1    Kuno, M.2    Seki, N.3    Yu, W.G.4    Yamaoka, M.5    Yamashita, M.6
  • 32
    • 0842322822 scopus 로고    scopus 로고
    • Mouse strain differences in eosinophilic airway inflammation caused by intratracheal instillation of mite allergen and diesel exhaust particles
    • Ichinose T., Takano H., Sadakane K., Yanagisawa R., Yoshikawa T., Sagai M., et al. Mouse strain differences in eosinophilic airway inflammation caused by intratracheal instillation of mite allergen and diesel exhaust particles. J Appl Toxicol 24 (2004) 69-76
    • (2004) J Appl Toxicol , vol.24 , pp. 69-76
    • Ichinose, T.1    Takano, H.2    Sadakane, K.3    Yanagisawa, R.4    Yoshikawa, T.5    Sagai, M.6
  • 34
    • 0026674684 scopus 로고
    • N omega-amino-L-arginine, an inhibitor of nitric oxide synthase, raises vascular resistance but increases mortality rates in awake canines challenged with endotoxin
    • Cobb J.P., Natanson C., Hoffman W.D., Lodato R.F., Banks S., Koev C.A., et al. N omega-amino-L-arginine, an inhibitor of nitric oxide synthase, raises vascular resistance but increases mortality rates in awake canines challenged with endotoxin. J Exp Med 176 (1992) 1175-1182
    • (1992) J Exp Med , vol.176 , pp. 1175-1182
    • Cobb, J.P.1    Natanson, C.2    Hoffman, W.D.3    Lodato, R.F.4    Banks, S.5    Koev, C.A.6
  • 35
    • 4444273012 scopus 로고    scopus 로고
    • Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: effect on survival in patients with septic shock
    • Lopez A., Lorente J.A., Steingrub J., Bakker J., McLuckie A., Willatts S., et al. Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: effect on survival in patients with septic shock. Crit Care Med 32 (2004) 21-30
    • (2004) Crit Care Med , vol.32 , pp. 21-30
    • Lopez, A.1    Lorente, J.A.2    Steingrub, J.3    Bakker, J.4    McLuckie, A.5    Willatts, S.6
  • 36
    • 2442538125 scopus 로고    scopus 로고
    • Critical roles of intracellular thiols and calcium in parthenolide-induced apoptosis in human colorectal cancer cells
    • Zhang S., Ong C.N., and Shen H.M. Critical roles of intracellular thiols and calcium in parthenolide-induced apoptosis in human colorectal cancer cells. Cancer Lett 208 (2004) 143-153
    • (2004) Cancer Lett , vol.208 , pp. 143-153
    • Zhang, S.1    Ong, C.N.2    Shen, H.M.3


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