Inhibition of oxygen radical formation by methylene blue, aspirin, or α-lipoic acid, prevents bacterial-lipopolysaccharide-induced fever

Molecular and Cellular Biochemistry

Volumn 247, Issue 1-2, 2003, Pages 83-94

  Riedel, Walter ^a   Lang, Uwe ^a   Oetjen, Ulrich ^a   Schlapp, Ulrike ^a   Shibata, Masaaki ^b  

^a MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^b YAMANASHI INSTITUTE OF ENVIRONMENTAL SCIENCES   (Japan)

Author keywords

Catalase; Fever; Lipoic acid; LPS; NMDA receptor; Oxidative stress; Redox homeostasis; Temperature homeostasis

Indexed keywords

ACETYLSALICYLIC ACID; ASCORBIC ACID; BACTERIUM LIPOPOLYSACCHARIDE; CATALASE; DIHYDROLIPOATE; DITHIOTHREITOL; FORMAZAN; GLUTAMIC ACID; HYDROPEROXIDE; INDOMETACIN; METHYLENE BLUE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITROBLUE TETRAZOLIUM; OXYGEN RADICAL; THIOCTIC ACID; THIOL GROUP; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ANTIPYRETIC ACTIVITY; BLOOD; BLOOD BRAIN BARRIER; BLOOD LEVEL; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CORE TEMPERATURE; CYTOKINE RELEASE; ENZYME INACTIVATION; FEMALE; FEVER; HEAT LOSS; HUMAN; HYPOTHERMIA; INCUBATION TIME; LATENT PERIOD; LEUKOCYTE COUNT; NERVE CELL EXCITABILITY; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; RABBIT; REVIEW; THERMOREGULATION;

ANIMALS; ANTIOXIDANTS; ASPIRIN; BACTERIAL INFECTIONS; BRAIN; CATALASE; ENDOTOXINS; FEMALE; FEVER; FORMAZANS; HYDROGEN PEROXIDE; INJECTIONS, INTRAVENOUS; LIPOPOLYSACCHARIDES; METHYLENE BLUE; PERFUSION; RABBITS; REACTIVE OXYGEN SPECIES; SUBARACHNOID SPACE; THIOCTIC ACID; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; BACTERIA (MICROORGANISMS); ORYCTOLAGUS CUNICULUS;

EID: 0038419584     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1024142400835     Document Type: Review

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