Anti-inflammatory activity of an ethanolic Caesalpinia sappan extract in human chondrocytes and macrophages

Journal of Ethnopharmacology

Volumn 138, Issue 2, 2011, Pages 364-372

  Wu, Shengqian Q ^a   Otero, Miguel ^b   Unger, Frank M ^a   Goldring, Mary B ^b   Phrutivorapongkul, Ampai ^c   Chiari, Catharina ^d   Kolb, Alexander ^d   Viernstein, Helmut ^a   Toegel, Stefan ^a,b,d  

^a UNIVERSITY OF VIENNA   (Austria)

^b HOSPITAL FOR SPECIAL SURGERY   (United States)

^c CHIANG MAI UNIVERSITY   (Thailand)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Caesalpinia sappan; Chondrocytes; COX 2; Cytokine; Inflammation; Osteoarthritis

Indexed keywords

CAESALPINIA SAPPAN EXTRACT; CYCLOOXYGENASE 2; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; NITRIC OXIDE SYNTHASE; PROTEIN P50; PROTEIN P56; TUMOR NECROSIS FACTOR ALPHA;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARTILAGE CELL; CELL ISOLATION; CELL STIMULATION; CELL VIABILITY; HUMAN; HUMAN CELL; MACROPHAGE; NUCLEOTIDE SEQUENCE; OSTEOARTHRITIS; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION;

ANTI-INFLAMMATORY AGENTS; BASE SEQUENCE; CAESALPINIA; CHONDROCYTES; CYCLOOXYGENASE 2; DNA PRIMERS; ETHANOL; HUMANS; MACROPHAGES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PLANT EXTRACTS; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION;

CAESALPINIA SAPPAN;

EID: 81255160555     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.09.011     Document Type: Article

References (42)

1. S.B. Abramson Nitric oxide in inflammation and pain associated with osteoarthritis Arthritis Research & Therapy 2 2008
2. S.B. Abramson, and M. Attur Developments in the scientific understanding of osteoarthritis Arthritis Research & Therapy 11 2009 227
3. V.C. Allport, D.M. Slater, R. Newton, and P.R. Bennett NF-kappaB and AP-1 are required for cyclo-oxygenase 2 gene expression in amnion epithelial cell line (WISH) Molecular Human Reproduction 6 2000 561 565 (Pubitemid 30365803)
4. L.G. Ameye, and W.S. Chee Osteoarthritis and nutrition from nutraceuticals to functional foods: a systematic review of the scientific evidence Arthritis Research & Therapy 8 2009 R127
5. M. Attur, H.E. Al-Mussawir, J. Patel, A. Kitay, M. Dave, G. Palmer, M.H. Pillinger, and S.B. Abramson Prostaglandin E2 exerts catabolic effects in osteoarthritis cartilage: evidence for signaling via the EP4 receptor Journal of Immunology 181 2008 5082 5088
6. S. Badami, S. Moorkoth, S.R. Rai, E. Kannan, and S. Bhojraj Antioxidant activity of Caesalpinia sappan heartwood Biological and Pharmaceutical Bulletin 26 2003 1534 1537 (Pubitemid 41699630)
7. I.K. Bae, H.Y. Min, A.R. Han, E.K. Seo, and S.K. Lee Suppression of lipopolysaccharide-induced expression of inducible nitric oxide synthase by brazilin in RAW 264.7 macrophage cells European Journal of Pharmacology 513 2005 237 242
8. N.I. Baek, S.G. Jeon, E.M. Ahn, J.T. Hahn, J.H. Bahn, J.S. Jang, S.W. Cho, J.K. Park, and S.Y. Choi Anticonvulsant compounds from the wood of Caesalpinia sappan L Archives of Pharmacal Research 23 2000 344 348
9. I. Batubara, T. Mitsunaga, and H. Ohashi Brazilin from Caesalpinia sappan wood as an antiacne agent Journal of Wood Science 56 2010 77 81
10. M.J. Benito, D.J. Veale, O. FitzGerald, W.B. van den Berg, and B. Bresnihan Synovial tissue inflammation in early and late osteoarthritis Annals of the Rheumatic Diseases 64 2005 1263 1267 (Pubitemid 41206240)
11. J. Bondeson, S.D. Wainwright, S. Lauder, N. Amos, and C.E. Hughes The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis Arthritis Research & Therapy 8 2006 187
12. C.S. Bonnet, and D.A. Walsh Osteoarthritis, angiogenesis and inflammation Rheumatology 44 2005 7 16 (Pubitemid 40136474)
13. S.A. Bustin, J.F. Beaulieu, J. Huggett, R. Jaggi, F.S. Kibenge, P.A. Olsvik, L.C. Penning, and S. Toegel MIQE précis: practical implementation of minimum standard guidelines for fluorescence-based quantitative real-time PCR experiments BMC Molecular Biology 11 2010 74
14. Y.P. Chen, L. Liu, Y.H. Zhou, J. Wen, Y. Jiang, and P.F. Tu Chemical constituents from Sappan Lignum Journal of Chinese Pharmaceutical Sciences 17 2008 82 86
15. China Pharmacopoeia Commission The Chinese Pharmacopoeia, 2010 ed. 2010 China Medical Science Press Beijing p. 153
16. A.L. Clutterbuck, K.E. Asplin, P. Harris, D. Allaway, and A. Mobasheri Targeting matrix metalloproteinases in inflammatory conditions Current Drug Target 10 2009 1245 1254
17. L.J. Crofford, B. Tan, C.J. McCarthy, and T. Hla Involvement of nuclear factor kappa B in the regulation of cyclooxygenase-2 expression by interleukin-1 in rheumatoid synoviocytes Arthritis & Rheumatism 40 1997 226 236 (Pubitemid 27114086)
18. A.M. Fendrick, and B.P. Greenberg A review of the benefits and risks of nonsteroidal anti-inflammatory drugs in the management of mild-to-moderate osteoarthritis Osteopathic Medicine and Primary Care 3 2009 1
19. M.B. Goldring, and S.R. Goldring Osteoarthritis Journal of Cellular Physiology 213 2007 626 634 (Pubitemid 350058254)
20. M.B. Goldring, and K.B. Marcu Cartilage homeostasis in health and rheumatic diseases Arthritis Research & Therapy 11 2009 224
21. M. Gosset, A. Pigenet, C. Salvat, F. Berenbaum, and C.J. Jacques Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1 Journal of Immunology 185 2010 6244 6252
22. F.T. Grall, W.C. Prall, W. Wei, X. Gu, J.Y. Cho, B.K. Choy, L.F. Zerbini, M.S. Inan, S.R. Goldring, E.M. Gravallese, M.B. Goldring, P. Oettgen, and T.A. Libermann The Ets transcription factor ESE-1 mediates induction of the COX-2 gene by LPS in monocytes The FEBS Journal 272 2005 1676 1687 (Pubitemid 40516218)
23. C.H. Hong, S.K. Hur, O.J. Oh, S.S. Kim, K.A. Nam, and S.K. Lee Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells Journal of Ethnopharmacology 83 2002 153 159 (Pubitemid 36164741)
24. H. Hikino, T. Taguchi, H. Fujimura, and Y. Hiramatsu Antiinflammatory principles of Caesalpinia sappan wood and of Haematoxylon campechianum wood Planta Medica 31 1977 214 220 (Pubitemid 8083771)
25. C.M. Hu, Y.H. Liu, K.P. Cheah, J.S. Li, C.S. Lam, W.Y. Yu, and C.S. Choy Heme oxygenase-1 mediates the inhibitory actions of brazilin in RAW264.7 macrophages stimulated with lipopolysaccharide Journal of Ethnopharmacology 121 2009 79 85
26. I.Y. Jeong, C.H. Jin, Y.D. Park, H.J. Lee, D.S. Choi, M.W. Byun, and Y.J. Kim Anti-inflammatory activity of an ethanol extract of Caesalpinia sappan L. in LPS-induced RAW 264.7 cells Journal of Food Science and Nutrition 13 2008 253 258
27. M.J. Lee, H.S. Lee, H.J. Jung, C.S. Lee, J.E. Kim, H.I. Moon, and W.H. Park Caesalpinia sappan L. ameliorates hypercholesterolemia in C57BL/6 mice and suppresses inflammatory responses in human umbilical vein endothelial cells (HUVECs) by antioxidant mechanism Immunopharmacology and Immunotoxicology 32 2010 671 679
28. A.L. Liu, S.H. Shu, H.L. Qin, S.M. Lee, Y.T. Wang, and G.H. Du In vitro anti-influenza viral activities of constituents from Caesalpinia sappan Planta Medica 75 2009 337 339
29. Y. Sasaki, T. Hosokawa, M. Nagai, and S. Nagumo In vitro study for inhibition of NO production about constituents of Sappan Lignum Biological & Pharmaceutical Bulletin 30 2007 193 196 (Pubitemid 46066346)
30. J. Shen, H. Zhang, H. Lin, H. Su, D. Xing, and L. Du Brazilein protects the brain against focal cerebral ischemia reperfusion injury correlating to inflammatory response suppression European Journal of Pharmacology 558 2007 88 95 (Pubitemid 46328876)
31. S. Sireeratawong, P. Piyabhan, T. Singhalak, Y. Wongkrajang, R. Temsiririkkul, J. Punsrirat, N. Ruangwises, S. Saraya, N. Lerdvuthisopon, and K. Jaijoy Toxicity evaluation of sappan wood extract in rats Journal of The Medical Association of Thailand 93 2010 S50 S57
32. R. Studer, D. Jaffurs, M. Stefanovic-Racic, P.D. Robbins, and C.H. Evans Nitric oxide in osteoarthritis Osteoarthritis Cartilage 7 1999 377 379 (Pubitemid 29331553)
33. The Society of Japanese and Pharmacopoeia The Japanese Pharmacopoeia 15th ed 2006 Hirokawa Publishing Co., Ltd Tokyo
34. B. Thomas, F. Berenbaum, L. Humbert, H. Bian, G. Bereziat, L. Crofford, and J.L. Olivier Critical role of C/ EBPdelta and C/ EBPbeta factors in the stimulation of the cyclooxygenase-2 gene transcription by interleukin-1beta in articular chondrocytes European Journal of Biochemistry 267 2000 6798 6809
35. S. Toegel, W. Huang, C. Piana, F.M. Unger, M. Wirth, M.B. Goldring, F. Gabor, and H. Viernstein Selection of reliable reference genes for qPCR studies on chondroprotective action BMC molecular biology 26 2007 8 13
36. S. Toegel, V.E. Plattner, S.Q. Wu, C. Chiari, F. Gabor, F.M. Unger, M.B. Goldring, S. Nehrer, H. Viernstein, and M. Wirth Lectin binding patterns reflect the phenotypic status of in vitro chondrocyte models In Vitro Cellular & Developmental Biology-Animal 45 2009 351 360
37. S. Toegel, M. Pabst, S.Q. Wu, J. Grass, M.B. Goldring, C. Chiari, A. Kolb, F. Altmann, H. Viernstein, and F.M. Unger Phenotype-related differential α-2,6- or α-2,3-sialylation of glycoprotein N-glycans in human chondrocytes Osteoarthritis and Cartilage 18 2010 240 248
38. T. Tsuruda, L.C. Costello-Boerrigter, and J.C. Burnett Matrix metalloproteinases: pathways of induction by bioactive molecules Heart Failure Reviews 9 2004 53 61 (Pubitemid 38196077)
39. Vandesompele, J., De Preter, K., Pattyn, F., Poppe, B., Van Roy, N., De Paepe, A., Speleman, F., 2002. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biology. 3, research0034.
40. M. Washiyama, Y. Sasaki, T. Hosokawa, and S. Nagumo Anti-inflammatory constituents of Sappan Lignum Biological and Pharmaceutical Bulletin 32 2009 941 944
41. H.X. Xu, and S.F. Lee The antibacterial principle of Caesalpinia sappan Phytotherapy Research 18 2004 647 651
42. E.J. You, L.Y. Khil, W.J. Kwak, H.S. Won, S.H. Chae, B.H. Lee, and C.K. Moon Effects of brazilin on the production of fructose-2 6-bisphosphate in rat hepatocytes Journal of Ethnopharmacology 102 2005 53 57