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Volumn 8, Issue , 2007, Pages

Selection of reliable reference genes for qPCR studies on chondroprotective action

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 MICROGLOBULIN; BETA ACTIN; CHONDROPROTECTIVE AGENT; CURCUMIN; DIACETYLRHEIN; GLUCOSAMINE; GLYCERALDEHYDE 3 PHOSPHATE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE 1; INTERLEUKIN 1BETA; MESSENGER RNA; SUCCINATE DEHYDROGENASE; SUCCINATE DEHYDROGENASE COMPLEX SUBUNIT A; TRYPTOPHAN 5 MONOOXYGENASE ACTIVATION PROTEIN ZETA POLYPEPTIDE; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG; ANTHRAQUINONE DERIVATIVE; PROTECTIVE AGENT;

EID: 33947210775     PISSN: None     EISSN: 14712199     Source Type: Journal    
DOI: 10.1186/1471-2199-8-13     Document Type: Article
Times cited : (57)

References (42)
  • 2
    • 0033757277 scopus 로고    scopus 로고
    • Glucosamine and chondroitin sulfates in the treatment of osteoarthitis: A survey
    • 11127967
    • DeLosReyes BG Koda RT Lien EJ Glucosamine and chondroitin sulfates in the treatment of osteoarthitis: A survey Prog Drug Res 2000 55 81-103 11127967
    • (2000) Prog Drug Res , vol.55 , pp. 81-103
    • DeLosReyes, B.G.1    Koda, R.T.2    Lien, E.J.3
  • 3
    • 0027095967 scopus 로고
    • Antireactive properties of "chondroprotective" drugs
    • 1300311
    • Setnikar I Antireactive properties of "chondroprotective" drugs Int J Tissue React 1992 14 253-261 1300311
    • (1992) Int J Tissue React , vol.14 , pp. 253-261
    • Setnikar, I.1
  • 4
    • 0035157807 scopus 로고    scopus 로고
    • Evaluation of the structure modifying effects of diacerein in hip osteoarthritis
    • 10.1002/1529-0131(200111)44:11<2539::AID-ART434>3.0.CO;2-T 11710710
    • Dougados M Nguyen M Berdah L Mazieres B Vignon E Lequesne M Evaluation of the structure modifying effects of diacerein in hip osteoarthritis Arthritis Rheum 2001 44 2539-2547 10.1002/ 1529-0131(200111)44:11<2539::AID-ART434>3.0.CO;2-T 11710710
    • (2001) Arthritis Rheum , vol.44 , pp. 2539-2547
    • Dougados, M.1    Nguyen, M.2    Berdah, L.3    Mazieres, B.4    Vignon, E.5    Lequesne, M.6
  • 5
    • 3242755776 scopus 로고    scopus 로고
    • A herbal remedy, Hyben Vital (stand. powder of a subspecies of Rosa canina fruits), reduces pain and improves general wellbeing in patients with osteoarthritis - A double-blind, placebo-controlled, randomised trial
    • 10.1016/j.phymed.2004.01.001 15330493
    • Rein E Kharazmi A Winther K A herbal remedy, Hyben Vital (stand. powder of a subspecies of Rosa canina fruits), reduces pain and improves general wellbeing in patients with osteoarthritis - a double-blind, placebo-controlled, randomised trial Phytomedicine 2004 11 383-391 10.1016/j.phymed.2004.01.001 15330493
    • (2004) Phytomedicine , vol.11 , pp. 383-391
    • Rein, E.1    Kharazmi, A.2    Winther, K.3
  • 6
    • 0030814409 scopus 로고    scopus 로고
    • Prophylactic and therapeutic effects of n-3 polyunsaturated fatty acids, capsaicin, and curcumin on adjuvant induced arthritis in rats
    • 10.1016/S0955-2863(97)00047-8
    • Joe B Lokesh BR Prophylactic and therapeutic effects of n-3 polyunsaturated fatty acids, capsaicin, and curcumin on adjuvant induced arthritis in rats J Nutr Biochem 1997 8 397-407 10.1016/ S0955-2863(97)00047-8
    • (1997) J Nutr Biochem , vol.8 , pp. 397-407
    • Joe, B.1    Lokesh, B.R.2
  • 7
    • 0041883590 scopus 로고    scopus 로고
    • Rhein inhibits interleukin-1β-induced activation of MEK/ERK pathway and DNA binding of NF-kB and AP-1 in chondrocytes cultured in hypoxia: A potential mechanism for its disease-modifying effect in osteoarthritis
    • 10.1023/A:1025040631514 14527176
    • Martin G Bogdanowicz P Domagala F Ficheux H Pujol JP Rhein inhibits interleukin-1β-induced activation of MEK/ERK pathway and DNA binding of NF-kB and AP-1 in chondrocytes cultured in hypoxia: A potential mechanism for its disease-modifying effect in osteoarthritis Inflammation 2003 27 233-246 10.1023/A:1025040631514 14527176
    • (2003) Inflammation , vol.27 , pp. 233-246
    • Martin, G.1    Bogdanowicz, P.2    Domagala, F.3    Ficheux, H.4    Pujol, J.P.5
  • 8
    • 0038344684 scopus 로고    scopus 로고
    • Glucosamine sulfate modulates the levels of aggrecan and matrix metalloproteinase-3 synthesized by cultured human osteoarthritis articular chondrocytes
    • 10.1016/S1063-4584(03)00052-9
    • Dodge GR Jimenez SA Glucosamine sulfate modulates the levels of aggrecan and matrix metalloproteinase-3 synthesized by cultured human osteoarthritis articular chondrocytes Osteoarthr Cartilage 2003 11 424-432 10.1016/S1063-4584(03)00052-9
    • (2003) Osteoarthr Cartilage , vol.11 , pp. 424-432
    • Dodge, G.R.1    Jimenez, S.A.2
  • 9
    • 0027076009 scopus 로고
    • In-vitro evaluation of drugs proposed as chondroprotective agents
    • 1300309
    • Bassleer C Henrotin Y Franchimont P In-vitro evaluation of drugs proposed as chondroprotective agents Int J Tissue React 1992 14 231-241 1300309
    • (1992) Int J Tissue React , vol.14 , pp. 231-241
    • Bassleer, C.1    Henrotin, Y.2    Franchimont, P.3
  • 10
    • 11144238289 scopus 로고    scopus 로고
    • Triptolide suppresses proinflammatory cytokine-induced matrix metalloproteinase and aggrecanase-1 gene expression in chondrocytes
    • 10.1016/j.bbrc.2004.12.020
    • Liacini A Sylvester J Zafarullah M Triptolide suppresses proinflammatory cytokine-induced matrix metalloproteinase and aggrecanase-1 gene expression in chondrocytes Biochem Bioph Res Co 2005 327 320-327 10.1016/ j.bbrc.2004.12.020
    • (2005) Biochem Bioph Res Co , vol.327 , pp. 320-327
    • Liacini, A.1    Sylvester, J.2    Zafarullah, M.3
  • 11
    • 0033808633 scopus 로고    scopus 로고
    • Glucosamine and chondroitin for osteoarthritis: To recommend or not to recommend?
    • 10.1002/1529-0131(200008)13:4<179::AID-ANR1>3.0.CO;2-X 14635271
    • Felson DT McAlindon TE Glucosamine and chondroitin for osteoarthritis: to recommend or not to recommend? Arthritis Care Res 2000 13 179-182 10.1002/1529-0131(200008)13:4<179::AID-ANR1>3.0.CO;2-X 14635271
    • (2000) Arthritis Care Res , vol.13 , pp. 179-182
    • Felson, D.T.1    McAlindon, T.E.2
  • 12
    • 0842267170 scopus 로고    scopus 로고
    • Structure-modifying agents for osteoarthritis: An update
    • 10.1016/S1297-319X(03)00129-5 14769516
    • Richette P Bardin T Structure-modifying agents for osteoarthritis: An update Joint Bone Spine 2004 71 18-23 10.1016/S1297-319X(03)00129-5 14769516
    • (2004) Joint Bone Spine , vol.71 , pp. 18-23
    • Richette, P.1    Bardin, T.2
  • 14
    • 0038171215 scopus 로고    scopus 로고
    • 'Natural remedies' in the treatment of osteoarthritis
    • 10.2165/00002512-200320070-00004
    • Walker-Bone K 'Natural remedies' in the treatment of osteoarthritis Drug Aging 2003 20 517-526 10.2165/00002512-200320070-00004
    • (2003) Drug Aging , vol.20 , pp. 517-526
    • Walker-Bone, K.1
  • 15
    • 0242606952 scopus 로고    scopus 로고
    • Homeostasis of the extracellular matrix of normal and osteoarthritic human articular cartilage chondrocytes in vitro
    • 10.1016/S1063-4584(03)00168-7
    • Wang J Verdonk P Elewaut D Veys EM Verbruggen G Homeostasis of the extracellular matrix of normal and osteoarthritic human articular cartilage chondrocytes in vitro Osteoarthr Cartilage 2003 11 801-809 10.1016/S1063-4584(03)00168-7
    • (2003) Osteoarthr Cartilage , vol.11 , pp. 801-809
    • Wang, J.1    Verdonk, P.2    Elewaut, D.3    Veys, E.M.4    Verbruggen, G.5
  • 16
    • 0034121686 scopus 로고    scopus 로고
    • Molecular basis and clinical use of biochemical markers of bone, cartilage and synovium in joint diseases
    • 10.1002/1529-0131(200005)43:5<953::AID-ANR1>3.0.CO;2-Q 10817547
    • Garnero P Rousseau JC Delmas PD Molecular basis and clinical use of biochemical markers of bone, cartilage and synovium in joint diseases Arthritis Rheum 2000 43 953-968 10.1002/ 1529-0131(200005)43:5<953::AID-ANR1>3.0.CO;2-Q 10817547
    • (2000) Arthritis Rheum , vol.43 , pp. 953-968
    • Garnero, P.1    Rousseau, J.C.2    Delmas, P.D.3
  • 17
    • 0035076295 scopus 로고    scopus 로고
    • Articular cartilage and changes in arthritis. An introduction: Cell biology of osteoarthritis
    • 128887 11178118 10.1186/ar148
    • Sandell LJ Aigner T Articular cartilage and changes in arthritis. An introduction: Cell biology of osteoarthritis Arthritis Res 2001 3 107-113 128887 11178118 10.1186/ar148
    • (2001) Arthritis Res , vol.3 , pp. 107-113
    • Sandell, L.J.1    Aigner, T.2
  • 18
    • 0037280454 scopus 로고    scopus 로고
    • Dose-dependent effects of corticosteroids on the expression of matrix-related genes in normal and cytokine-treated articular chondrocytes
    • 10.1007/s000110300012 12608648
    • Richardson DW Dodge GR Dose-dependent effects of corticosteroids on the expression of matrix-related genes in normal and cytokine-treated articular chondrocytes Inflamm Res 2003 52 39-49 10.1007/s000110300012 12608648
    • (2003) Inflamm Res , vol.52 , pp. 39-49
    • Richardson, D.W.1    Dodge, G.R.2
  • 20
    • 15044364010 scopus 로고    scopus 로고
    • Effects of curcumin (Diferuloylmethane) on nuclear factor kB signaling in Interleukin-1β-stimulated chondrocytes
    • 10.1196/annals.1329.067 15659840
    • Schulze-Tanzil G Mobasheri A Sendzik J John T Shakibaei M Effects of curcumin (Diferuloylmethane) on nuclear factor kB signaling in Interleukin-1β-stimulated chondrocytes Ann NY Acad Sci 2004 1030 578-586 10.1196/annals.1329.067 15659840
    • (2004) Ann NY Acad Sci , vol.1030 , pp. 578-586
    • Schulze-Tanzil, G.1    Mobasheri, A.2    Sendzik, J.3    John, T.4    Shakibaei, M.5
  • 21
    • 33645717235 scopus 로고    scopus 로고
    • The protective effect of licofelone on experimental osteoarthritis is correlated with the downregulation of gene expression and protein synthesis of several major cartilage catabolic factors: MMP-13, cathepsin K and aggrecanases
    • 1257437 16207326 10.1186/ar1788
    • Pelletier JP Boileau C Boily M Brunet J Mineau F Geng C Reboul P Laufer S Lajeunesse D Martel-Pelletier J The protective effect of licofelone on experimental osteoarthritis is correlated with the downregulation of gene expression and protein synthesis of several major cartilage catabolic factors: MMP-13, cathepsin K and aggrecanases Arthritis Res Ther 2005 7 R1091-1102 1257437 16207326 10.1186/ar1788
    • (2005) Arthritis Res Ther , vol.7
    • Pelletier, J.P.1    Boileau, C.2    Boily, M.3    Brunet, J.4    Mineau, F.5    Geng, C.6    Reboul, P.7    Laufer, S.8    Lajeunesse, D.9    Martel-Pelletier, J.10
  • 22
    • 33644666907 scopus 로고    scopus 로고
    • Glucosamine decreases expression of anabolic and catabolic genes in human osteoarthritic cartilage explants
    • 10.1016/j.joca.2005.10.001 16300972
    • Uitterlinden EJ Jahr H Koevoet JL Jenniskens YM Bierma-Zeinstra SM Degroot J Glucosamine decreases expression of anabolic and catabolic genes in human osteoarthritic cartilage explants Osteoarthritis Cartilage 2006 14 250-257 10.1016/j.joca.2005.10.001 16300972
    • (2006) Osteoarthritis Cartilage , vol.14 , pp. 250-257
    • Uitterlinden, E.J.1    Jahr, H.2    Koevoet, J.L.3    Jenniskens, Y.M.4    Bierma-Zeinstra, S.M.5    Degroot, J.6
  • 24
    • 33646267678 scopus 로고    scopus 로고
    • The chondroprotective actions of a natural product are associated with the activation of IGF-1 production by human chondrocytes despite the presence of IL-1β
    • 10.1186/1472-6882-6-13
    • Miller MJS Ahmed S Bobrowski P Haqqi TM The chondroprotective actions of a natural product are associated with the activation of IGF-1 production by human chondrocytes despite the presence of IL-1β BMC Complementary and Alternative Medicine 2006 6 13 10.1186/1472-6882-6-13
    • (2006) BMC Complementary and Alternative Medicine , vol.6 , pp. 13
    • Miller, M.J.S.1    Ahmed, S.2    Bobrowski, P.3    Haqqi, T.M.4
  • 25
    • 33745798175 scopus 로고    scopus 로고
    • Short-term gene expression changes in cartilage explants stimulated with IL-1β plus glucosamine and chondroitin sulfate
    • 16821268
    • Chan PS Caron JP Orth MW Short-term gene expression changes in cartilage explants stimulated with IL-1β plus glucosamine and chondroitin sulfate J Rheumatol 2006 33 1329-1340 16821268
    • (2006) J Rheumatol , vol.33 , pp. 1329-1340
    • Chan, P.S.1    Caron, J.P.2    Orth, M.W.3
  • 26
    • 21344471138 scopus 로고    scopus 로고
    • Real-time RT-PCR normalisation; strategies and considerations
    • 10.1038/sj.gene.6364190 15815687
    • Huggett J Dheda K Bustin S Zumla A Real-time RT-PCR normalisation; strategies and considerations Genes Immun 2005 6 279-284 10.1038/ sj.gene.6364190 15815687
    • (2005) Genes Immun , vol.6 , pp. 279-284
    • Huggett, J.1    Dheda, K.2    Bustin, S.3    Zumla, A.4
  • 27
    • 0034694128 scopus 로고    scopus 로고
    • Effect of experimental treatment on housekeeping gene expression: Validation by real-time, quantitative RT-PCR
    • 10.1016/S0165-022X(00)00129-9
    • Schmittgen TD Zakrajsek BA Effect of experimental treatment on housekeeping gene expression: Validation by real-time, quantitative RT-PCR J Biochem Bioph Meth 2000 46 69-81 10.1016/S0165-022X(00)00129-9
    • (2000) J Biochem Bioph Meth , vol.46 , pp. 69-81
    • Schmittgen, T.D.1    Zakrajsek, B.A.2
  • 28
    • 0033575003 scopus 로고    scopus 로고
    • Direct comparison of GAPDH, β-actin, cyclophilin, and 28S rRNA as internal standards for quantifying RNA levels under hypoxia
    • 10.1006/bbrc.1999.0815
    • Zhong H Simons JW Direct comparison of GAPDH, β-actin, cyclophilin, and 28S rRNA as internal standards for quantifying RNA levels under hypoxia Biochem Bioph Res Co 1999 259 523-526 10.1006/bbrc.1999.0815
    • (1999) Biochem Bioph Res Co , vol.259 , pp. 523-526
    • Zhong, H.1    Simons, J.W.2
  • 29
    • 3142615272 scopus 로고    scopus 로고
    • Validation of housekeeping genes for normalizing RNA expression in real-time PCR
    • 15283208
    • Dheda K Huggett JF Bustin SA Johnson MA Rook G Zumla A Validation of housekeeping genes for normalizing RNA expression in real-time PCR Biotechniques 2004 37 112-119 15283208
    • (2004) Biotechniques , vol.37 , pp. 112-119
    • Dheda, K.1    Huggett, J.F.2    Bustin, S.A.3    Johnson, M.A.4    Rook, G.5    Zumla, A.6
  • 30
    • 33645505177 scopus 로고    scopus 로고
    • Comparison of in vitro and in vivo reference genes for internal standardization of real-time PCR data
    • 16526406
    • Gilsbach R Kouta M Boenisch H Bruess M Comparison of in vitro and in vivo reference genes for internal standardization of real-time PCR data Biotechniques 2006 40 2 173-7 16526406
    • (2006) Biotechniques , vol.40 , Issue.2 , pp. 173-177
    • Gilsbach, R.1    Kouta, M.2    Boenisch, H.3    Bruess, M.4
  • 31
    • 33745610748 scopus 로고    scopus 로고
    • Selection of a set of reliable reference genes for quantificative real-time PCR in normal equine skin and equine sarcoids
    • 1484482 16643647 10.1186/1472-6750-6-24
    • Bogaert L VanPoucke M DeBaere Peelman L Gasthuys F Martens A Selection of a set of reliable reference genes for quantificative real-time PCR in normal equine skin and equine sarcoids BMC Biotechnology 2006 6 24 1484482 16643647 10.1186/1472-6750-6-24
    • (2006) BMC Biotechnology , vol.6 , pp. 24
    • Bogaert, L.1    VanPoucke, M.2    DeBaere Peelman, L.3    Gasthuys, F.4    Martens, A.5
  • 32
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • 10.1186/gb-2002-3-7-research0034
    • Vandesompele J DePreter K Pattyn F Poppe B VanRoy N DePaepe A Speleman F Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes Genome Biology 2002 3 34 10.1186/gb-2002-3-7-research0034
    • (2002) Genome Biology , vol.3 , pp. 34
    • Vandesompele, J.1    DePreter, K.2    Pattyn, F.3    Poppe, B.4    VanRoy, N.5    DePaepe, A.6    Speleman, F.7
  • 34
    • 27644563899 scopus 로고    scopus 로고
    • The implications of using an inappropriate reference gene for real-time reverse transcription PCR data normalization
    • 10.1016/j.ab.2005.05.022 16054107
    • Dheda K Huggett JF Chang JS Kim LU Bustin SA Johnson MA Rook GAW Zumla A The implications of using an inappropriate reference gene for real-time reverse transcription PCR data normalization Anal Biochem 2005 344 141-143 10.1016/j.ab.2005.05.022 16054107
    • (2005) Anal Biochem , vol.344 , pp. 141-143
    • Dheda, K.1    Huggett, J.F.2    Chang, J.S.3    Kim, L.U.4    Bustin, S.A.5    Johnson, M.A.6    Rook, G.A.W.7    Zumla, A.8
  • 35
    • 19444368764 scopus 로고    scopus 로고
    • Effect of mechanical loading on mRNA levels of common endogenous controls in articular chondrocytes and intervertebral disk
    • 10.1016/j.ab.2004.10.005 15907885
    • Lee CR Grad S MacLean JJ Iatridis JC Alini M Effect of mechanical loading on mRNA levels of common endogenous controls in articular chondrocytes and intervertebral disk Anal Biochem 2005 341 372-375 10.1016/j.ab.2004.10.005 15907885
    • (2005) Anal Biochem , vol.341 , pp. 372-375
    • Lee, C.R.1    Grad, S.2    MacLean, J.J.3    Iatridis, J.C.4    Alini, M.5
  • 36
    • 33644826578 scopus 로고    scopus 로고
    • Evaluation of p16 and Id1 status and endogenous reference genes in human chondrosarcoma by real-time PCR
    • 16273214
    • Asp J Brantsing C Lovstedt K Benassi MS Inerot S Gamberi G Picci P Lindahl A Evaluation of p16 and Id1 status and endogenous reference genes in human chondrosarcoma by real-time PCR Int J Oncol 2005 27 1577-1582 16273214
    • (2005) Int J Oncol , vol.27 , pp. 1577-1582
    • Asp, J.1    Brantsing, C.2    Lovstedt, K.3    Benassi, M.S.4    Inerot, S.5    Gamberi, G.6    Picci, P.7    Lindahl, A.8
  • 37
    • 14044265394 scopus 로고    scopus 로고
    • Pitfalls of quantitative real-time reverse-transcription polymerase chain reaction
    • 15331581
    • Bustin SA Nolan T Pitfalls of quantitative real-time reverse-transcription polymerase chain reaction J Biomol Tech 2004 15 3 155-6 15331581
    • (2004) J Biomol Tech , vol.15 , Issue.3 , pp. 155-156
    • Bustin, S.A.1    Nolan, T.2
  • 38
    • 0037248812 scopus 로고    scopus 로고
    • RTPrimerDB: The Real-Time PCR primer and probe database
    • 165458 12519963 10.1093/nar/gkg011
    • Pattyn F Speleman F DePaepe A Vandesompele J RTPrimerDB: The Real-Time PCR primer and probe database Nucleic Acids Res 2003 31 122-123 http://medgen.ugent.be/rtprimerdb/ 165458 12519963 10.1093/nar/gkg011
    • (2003) Nucleic Acids Res , vol.31 , pp. 122-123
    • Pattyn, F.1    Speleman, F.2    DePaepe, A.3    Vandesompele, J.4
  • 39
    • 1542375098 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) induces matrix metalloproteinase expression in immortalized chondrocytes
    • 10.1002/path.1527 14991903
    • Pufe T Harde V Petersen W Goldring MB Tillmann B Mentlein R Vascular endothelial growth factor (VEGF) induces matrix metalloproteinase expression in immortalized chondrocytes J Pathol 2004 202 367-374 10.1002/path.1527 14991903
    • (2004) J Pathol , vol.202 , pp. 367-374
    • Pufe, T.1    Harde, V.2    Petersen, W.3    Goldring, M.B.4    Tillmann, B.5    Mentlein, R.6
  • 40
    • 0346850618 scopus 로고    scopus 로고
    • Molecular phenotyping of human chondrocyte cell lines T/C-28a2, T/C-28a4 and C-28/I2
    • 10.1002/art.11341 14673991
    • Finger F Schoerle C Zien A Gebhard Goldring MB Aigner T Molecular phenotyping of human chondrocyte cell lines T/C-28a2, T/C-28a4 and C-28/ I2 Arthritis Rheum 2003 48 3395-3403 10.1002/art.11341 14673991
    • (2003) Arthritis Rheum , vol.48 , pp. 3395-3403
    • Finger, F.1    Schoerle, C.2    Zien, A.3    Gebhard4    Goldring, M.B.5    Aigner, T.6
  • 42
    • 0037501113 scopus 로고    scopus 로고
    • Influence of glucosamine on matrix metalloproteinase expression and activity in lipopolysaccharide-stimulated equine chondrocytes
    • 10.2460/ajvr.2003.64.666 12828249
    • Byron CR Orth MW Venta PJ Lloyd JW Caron JP Influence of glucosamine on matrix metalloproteinase expression and activity in lipopolysaccharide-stimulated equine chondrocytes Am J Vet Res 2003 64 666-671 10.2460/ajvr.2003.64.666 12828249
    • (2003) Am J Vet Res , vol.64 , pp. 666-671
    • Byron, C.R.1    Orth, M.W.2    Venta, P.J.3    Lloyd, J.W.4    Caron, J.P.5


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