Structured three-dimensional co-culture of mesenchymal stem cells with chondrocytes promotes chondrogenic differentiation without hypertrophy

Osteoarthritis and Cartilage

Volumn 19, Issue 10, 2011, Pages 1210-1218

  Cooke, M E ^a   Allon, A A ^a   Cheng, T ^a   Kuo, A C ^a   Kim, H T ^a   Vail, T P ^a   Marcucio, R S ^a   Schneider, R A ^a   Lotz, J C ^a,b   Alliston, T ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b San Francisco   (United States)

Author keywords

Cartilage; Chondrocyte; Co culture; Mesenchymal stem cell; Osteoarthritis; Tissue engineering

Indexed keywords

AGGRECAN; COLLAGEN TYPE 10A1; COLLAGEN TYPE 1A1; COLLAGEN TYPE 2; COLLAGEN TYPE 2A1; COLLAGENASE 3; PROTEOGLYCAN; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ARTICLE; BILAMINAR CELL PELLET; CARTILAGE CELL; CELL DIFFERENTIATION; CELL ENLARGEMENT; CELL HYPERTROPHY; CELL STRUCTURE; CELL TYPE; CHONDROGENIC DIFFERENTIATION; COCULTURE; CONTROLLED STUDY; CULTURE MEDIUM; FEMALE; GENE EXPRESSION; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; JUVENILE CHONDROCYTE; MALE; MESENCHYMAL STEM CELL; MICROENVIRONMENT; NORMAL HUMAN; OSTEOARTHRITIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AGGRECANS; CARTILAGE, ARTICULAR; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CHONDROCYTES; COLLAGEN; CORE BINDING FACTOR ALPHA 1 SUBUNIT; HUMANS; MALE; MATRIX METALLOPROTEINASE 13; MESENCHYMAL STEM CELLS; PROTEOGLYCANS; SOX9 TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA;

EID: 81155162514     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2011.07.005     Document Type: Article

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