The potential of human allogeneic juvenile chondrocytes for restoration of articular cartilage

American Journal of Sports Medicine

Volumn 38, Issue 7, 2010, Pages 1324-1333

  Adkisson, H Davis ^a   Martin, James A ^b   Amendola, Richard L ^b   Milliman, Curt ^a   Mauch, Kelsey A ^d   Katwal, Arbindra B ^a   Seyedin, Mitchell ^a   Amendola, Annuziato ^b   Streeter, Philip R ^d   Buckwalter, Joseph A ^b,c  

^a Isto Technologies Inc   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

agarose culture; aging; cartilage repair; chondrocyte transplantation; immunogenicity; juvenile human chondrocytes; neocartilage; serial expansion

Indexed keywords

COLLAGEN TYPE 2; COLLAGEN TYPE 9; PROTEOGLYCAN;

ADOLESCENT; ADULT; AGE; AGED; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL CULTURE; CELL DIFFERENTIATION; CHEMISTRY; CHONDROPATHY; CYTOLOGY; FEMALE; HUMAN; INFANT; LYMPHOCYTE ACTIVATION; MALE; METABOLISM; MIDDLE AGED; PHYSIOLOGY; REGENERATION; TRANSPLANTATION;

ADOLESCENT; ADULT; AGE FACTORS; AGED; CARTILAGE DISEASES; CARTILAGE, ARTICULAR; CELL DIFFERENTIATION; CELLS, CULTURED; CHONDROCYTES; COLLAGEN TYPE II; COLLAGEN TYPE IX; FEMALE; HUMANS; INFANT; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; PROTEOGLYCANS; REGENERATION; YOUNG ADULT;

EID: 77954344675     PISSN: 03635465     EISSN: 15523365     Source Type: Journal    
DOI: 10.1177/0363546510361950     Document Type: Article

References (43)

1. Adkisson HD, Gillis MP, Davis EC, Maloney W., Hruska KA In vitro generation of scaffold independent neocartilage. Clin Orthop Relat Res. 2001 ; 391 (Suppl): S280 - S294.
2. Adkisson HD, Milliman C., Zhang X., Mauch K., Maziarz RT, Streeter PR Immune evasion by neocartilage-derived chondrocytes: implications for biologic repair of joint articular cartilage. Stem Cell Res. 2010 ; 4: 57-68.
3. Aigner T., Gebhard PM, Schmid E., Bau B., Harley V., Poschl E. SOX9 expression does not correlate with type II collagen expression in adult articular chondrocytes. Matrix Biol. 2003 ; 22 (4). 363-372.
4. Aston JE, Bentley G. Repair of articular surfaces by allografts of articular and growth-plate cartilage. J Bone Joint Surg Br. 1986 ; 68 (1). 29-35.
5. Budde B., Blumbach K., Ylostalo J., et al. Altered integration of matrilin-3 into cartilage extracellular matrix in the absence of collagen IX. Mol Cell Biol. 2005 ; 25 (23). 10465-10478.
6. Bugbee WD Fresh osteochondral allografts. J Knee Surg. 2002 ; 15 (3). 191-195.
7. Bugbee WD, Convery FR Osteochondral allograft transplantation. Clin Sports Med. 1999 ; 18 (1). 67-75.
8. Chu CR, Convery FR, Akeson WH, Meyers M., Amiel D. Articular cartilage transplantation: clinical results in the knee. Clin Orthop Relat Res. 1999 ; 360: 159-168.
9. Coletti JM Jr, Akeson WH, Woo SL A comparison of the physical behavior of normal articular cartilage and the arthroplasty surface. J Bone Joint Surg Am. 1972 ; 54 (1). 147-160.
10. Dell'Accio F., De Bari C., Luyten FP Microenvironment and phenotypic stability specify tissue formation by human articular cartilage-derived cells in vivo. Exp Cell Res. 2003 ; 287 (1). 16-27.
11. Diab M., Wu JJ, Eyre DR Collagen type IX from human cartilage: a structural profile of intermolecular cross-linking sites. Biochem J. 1996 ; 314 (Pt 1). 327-332.
12. Eyre D. Collagen of articular cartilage. Arthritis Res. 2002 ; 4 (1). 30-35.
13. Farndale RW, Buttle DJ, Barrett AJ Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethyl-methylene blue. Biochim Biophys Acta. 1986 ; 883 (2). 173-177.
14. Fassler R., Schnegelsberg PN, Dausman J., et al. Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease. Proc Natl Acad Sci U S A. 1994 ; 91 (11). 5070-5074.
15. Feder J., Adkisson HD, Kizer N., et al. The promise of chondral repair using neocartilage. In: Sandell LJ GA, ed. Tissue Engineering in Musculoskeletal Clinical Practice. Rosemont, IL: American Academy of Orthopaedic Surgeons ; 2004: 219-226.
16. Gibson T., Curran RC, Davis WB The survival of living homograft cartilage in man. Transplant Bull. 1957 ; 4 (3). 105-106.
17. Hunter W. On the structure and disease of articulating cartilages. Philosophical Transactions of the Royal Society of London 1743 ; 42B: 514-521.
18. Jobanputra P., Corrigall V., Kingsley G., Panayi G. Cellular responses to human chondrocytes: absence of allogeneic responses in the presence of HLA-DR and ICAM-1. Clin Exp Immunol. 1992 ; 90 (2). 336-344.
19. Knutsen G., Drogset JO, Engebretsen L., et al. A randomized trial comparing autologous chondrocyte implantation with microfracture: findings at five years. J Bone Joint Surg Am. 2007 ; 89 (10). 2105-2112.
20. Knutsen G., Engebretsen L., Ludvigsen TC, et al. Autologous chondrocyte implantation compared with microfracture in the knee: a randomized trial. J Bone Joint Surg Am. 2004 ; 86 (3). 455-464.
21. Labarca C., Paigen K. A simple, rapid, and sensitive DNA assay procedure. Anal Biochem. 1980 ; 102 (2). 344-352.
22. Lefebvre V., de Crombrugghe B. Toward understanding SOX9 function in chondrocyte differentiation. Matrix Biol. 1998 ; 16 (9). 529-540.
23. Lefebvre V., Huang W., Harley VR, Goodfellow PN, de Crombrugghe B. SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene. Mol Cell Biol. 1997 ; 17 (4). 2336-2346.
24. Lu Y., Adkisson HD, Bogdanske J., et al. In vivo transplantation of neonatal ovine neocartilage allografts: determining the effectiveness of tissue transglutaminase. J Knee Surg. 2005 ; 18 (1). 31-42.
25. Mankin HJ The response of articular cartilage to mechanical injury. J Bone Joint Surg Am. 1982 ; 64 (3). 460-466.
26. Martin JA, Klingelhutz AJ, Moussavi-Harami F., Buckwalter JA Effects of oxidative damage and telomerase activity on human articular cartilage chondrocyte senescence. J Gerontol A Biol Sci Med Sci. 2004 ; 59 (4). 324-337.
27. Moussavi-Harami SF, Pedersen DR, Martin JA, Hillis SL, Brown TD Automated objective scoring of histologically apparent cartilage degeneration using a custom image analysis program. J Orthop Res. 2009 ; 27 (4). 522-528.
28. Nakata K., Ono K., Miyazaki J., et al. Osteoarthritis associated with mild chondrodysplasia in transgenic mice expressing alpha 1(IX) collagen chains with a central deletion. Proc Natl Acad Sci U S A. 1993 ; 90 (7). 2870-2874.
29. Namba RS, Meuli M., Sullivan KM, Le AX, Adzick NS Spontaneous repair of superficial defects in articular cartilage in a fetal lamb model. J Bone Joint Surg Am. 1998 ; 80 (1). 4-10.
30. Perka C., Schultz O., Lindenhayn K., et al. Joint cartilage repair with transplantation of embryonic chondrocytes embedded in collagen-fibrin matrices. Clin Exp Rheumatol. 2000 ; 18 (1). 13-22.
31. Pittenger MF, Mackay AM, Beck SC, et al. Multilineage potential of adult human mesenchymal stem cells. Science. 1999 ; 284 (5411). 143-147.
32. Pritzker KP, Gross AE, Langer F., Luk SC, Houpt JB Articular cartilage transplantation. Hum Pathol. 1977 ; 8 (6). 635-651.
33. Ruano-Ravina A., Jato Diaz M. Autologous chondrocyte implantation: a systematic review. Osteoarthritis Cartilage. 2006 ; 14 (1). 47-51.
34. Salai M., Ganel A., Horoszowski H. Fresh osteochondral allografts at the knee joint: good functional results in a follow-up study of more than 15 years. Arch Orthop Trauma Surg. 1997 ; 116 (6-7). 423-425.
35. Saris DB, Vanlauwe J., Victor J., et al. Characterized chondrocyte implantation results in better structural repair when treating symptomatic cartilage defects of the knee in a randomized controlled trial versus microfracture. Am J Sports Med. 2008 ; 36 (2). 235-246.
36. Sirlin CB, Brossmann J., Boutin RD, et al. Shell osteochondral allografts of the knee: comparison of MR imaging findings and immunologic responses. Radiology. 2001 ; 219 (1). 35-43.
37. Specchia N., Gigante A., Falciglia F., Greco F. Fetal chondral homo-grafts in the repair of articular cartilage defects. Bull Hosp Jt Dis. 1996 ; 54 (4). 230-235.
38. Thur J., Rosenberg K., Nitsche DP, et al. Mutations in cartilage oligomeric matrix protein causing pseudoachondroplasia and multiple epiphyseal dysplasia affect binding of calcium and collagen I, II, and IX. J Biol Chem. 2001 ; 276 (9). 6083-6092.
39. Tran-Khanh N., Hoemann CD, McKee MD, Henderson JE, Buschmann MD Aged bovine chondrocytes display a diminished capacity to produce a collagen-rich, mechanically functional cartilage extracellular matrix. J Orthop Res. 2005 ; 23 (6). 1354-1362.
40. von der Mark K., Gauss V., von der Mark H., Muller P. Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture. Nature. 1977 ; 267 (5611). 531-532.
41. Wood JJ, Malek MA, Frassica FJ, et al. Autologous cultured chondrocytes: adverse events reported to the United States Food and Drug Administration. J Bone Joint Surg Am. 2006 ; 88 (3). 503-507.
42. Zaucke F., Dinser R., Maurer P., Paulsson M. Cartilage oligomeric matrix protein (COMP) and collagen IX are sensitive markers for the differentiation state of articular primary chondrocytes. Biochem J. 2001 ; 358 (Pt 1). 17-24.
43. Zheng H., Martin JA, Duwayri Y., Falcon G., Buckwalter JA Impact of aging on rat bone marrow-derived stem cell chondrogenesis. J Gerontol A Biol Sci Med Sci. 2007 ; 62 (2). 136-148.