-
1
-
-
33746329868
-
Energy converting NADH: quinone oxidoreductase (complex I)
-
Brandt U. Energy converting NADH: quinone oxidoreductase (complex I). Annu. Rev. Biochem. 2006, 75:69-92.
-
(2006)
Annu. Rev. Biochem.
, vol.75
, pp. 69-92
-
-
Brandt, U.1
-
2
-
-
57049108103
-
Challenges in elucidating structure and mechanism of proton pumping NADH:ubiquinone oxidoreductase (complex I)
-
Zickermann V., Dröse S., Tocilescu M.A., Zwicker K., Kerscher S., Brandt U. Challenges in elucidating structure and mechanism of proton pumping NADH:ubiquinone oxidoreductase (complex I). J. Bioenerg. Biomembr. 2008, 40:475-483.
-
(2008)
J. Bioenerg. Biomembr.
, vol.40
, pp. 475-483
-
-
Zickermann, V.1
Dröse, S.2
Tocilescu, M.A.3
Zwicker, K.4
Kerscher, S.5
Brandt, U.6
-
3
-
-
66449105882
-
Architecture of complex I and its implications for electron transfer and proton pumping
-
Zickermann V., Kerscher S., Zwicker K., Tocilescu M.A., Radermacher M., Brandt U. Architecture of complex I and its implications for electron transfer and proton pumping. Biochim. Biophys. Acta 2009, 1787:574-583.
-
(2009)
Biochim. Biophys. Acta
, vol.1787
, pp. 574-583
-
-
Zickermann, V.1
Kerscher, S.2
Zwicker, K.3
Tocilescu, M.A.4
Radermacher, M.5
Brandt, U.6
-
4
-
-
33847687662
-
Respiratory complex I: mechanistic and structural insights provided by the crystal structure of the hydrophilic domain
-
Sazanov L.A. Respiratory complex I: mechanistic and structural insights provided by the crystal structure of the hydrophilic domain. Biochemistry 2007, 46:2275-2288.
-
(2007)
Biochemistry
, vol.46
, pp. 2275-2288
-
-
Sazanov, L.A.1
-
5
-
-
73849114263
-
Towards the molecular mechanism of respiratory complex I
-
Hirst J. Towards the molecular mechanism of respiratory complex I. Biochem. J. 2010, 425:327-339.
-
(2010)
Biochem. J.
, vol.425
, pp. 327-339
-
-
Hirst, J.1
-
6
-
-
33751574953
-
Bovine complex I is a complex of 45 different subunits
-
Carroll J., Fearnley I.M., Skehel J.M., Shannon R.J., Hirst J., Walker J.E. Bovine complex I is a complex of 45 different subunits. J. Biol. Chem. 2006, 281:32724-32727.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 32724-32727
-
-
Carroll, J.1
Fearnley, I.M.2
Skehel, J.M.3
Shannon, R.J.4
Hirst, J.5
Walker, J.E.6
-
7
-
-
52949098343
-
Subunit mass fingerprinting of mitochondrial complex I
-
Morgner N., Zickermann V., Kerscher S., Wittig I., Abdrakhmanova A., Barth H.D., Brutschy B., Brandt U. Subunit mass fingerprinting of mitochondrial complex I. Biochim. Biophys. Acta 2008, 1777:1384-1391.
-
(2008)
Biochim. Biophys. Acta
, vol.1777
, pp. 1384-1391
-
-
Morgner, N.1
Zickermann, V.2
Kerscher, S.3
Wittig, I.4
Abdrakhmanova, A.5
Barth, H.D.6
Brutschy, B.7
Brandt, U.8
-
8
-
-
0032490115
-
Procaryotic complex I (NDH-1), an overview
-
Yagi T., Yano T., Di Bernardo S., Matsuno-Yagi A. Procaryotic complex I (NDH-1), an overview. Biochim. Biophys. Acta 1998, 1364:125-133.
-
(1998)
Biochim. Biophys. Acta
, vol.1364
, pp. 125-133
-
-
Yagi, T.1
Yano, T.2
Di Bernardo, S.3
Matsuno-Yagi, A.4
-
9
-
-
0026077298
-
Electron microscopic analysis of the peripheral and membrane parts of mitochondrial NADH dehydrogenase (complex I)
-
Hofhaus G., Weiss H., Leonard K. Electron microscopic analysis of the peripheral and membrane parts of mitochondrial NADH dehydrogenase (complex I). J. Mol. Biol. 1991, 221:1027-1043.
-
(1991)
J. Mol. Biol.
, vol.221
, pp. 1027-1043
-
-
Hofhaus, G.1
Weiss, H.2
Leonard, K.3
-
10
-
-
0031592480
-
Three-dimensional structure of NADH-dehydrogenase from Neurospora crassa by electron microscopy and conical tilt reconstruction
-
Guenebaut V., Vincentelli R., Mills D., Weiss H., Leonard K. Three-dimensional structure of NADH-dehydrogenase from Neurospora crassa by electron microscopy and conical tilt reconstruction. J. Mol. Biol. 1997, 265:409-418.
-
(1997)
J. Mol. Biol.
, vol.265
, pp. 409-418
-
-
Guenebaut, V.1
Vincentelli, R.2
Mills, D.3
Weiss, H.4
Leonard, K.5
-
11
-
-
0032512616
-
Consistent structure between bacterial and mitochondrial NADH:ubiquinone oxidoreductase (complex I)
-
Guenebaut V., Schlitt A., Weiss H., Leonard K., Friedrich T. Consistent structure between bacterial and mitochondrial NADH:ubiquinone oxidoreductase (complex I). J. Mol. Biol. 1998, 276:105-112.
-
(1998)
J. Mol. Biol.
, vol.276
, pp. 105-112
-
-
Guenebaut, V.1
Schlitt, A.2
Weiss, H.3
Leonard, K.4
Friedrich, T.5
-
12
-
-
0032540273
-
Three-dimensional structure of bovine NADH:ubiquinone oxidoreductase (complex I) at 22Å in ice
-
Grigorieff N. Three-dimensional structure of bovine NADH:ubiquinone oxidoreductase (complex I) at 22Å in ice. J. Mol. Biol. 1998, 277:1033-1046.
-
(1998)
J. Mol. Biol.
, vol.277
, pp. 1033-1046
-
-
Grigorieff, N.1
-
13
-
-
0034691658
-
Biophysical and structural characterization of proton-translocating NADH-dehydrogenase (complex I) from the strictly aerobic yeast Yarrowia lipolytica
-
Djafarzadeh R., Kerscher S., Zwicker K., Radermacher M., Lindahl M., Schägger H., Brandt U. Biophysical and structural characterization of proton-translocating NADH-dehydrogenase (complex I) from the strictly aerobic yeast Yarrowia lipolytica. Biochim. Biophys. Acta 2000, 1459:230-238.
-
(2000)
Biochim. Biophys. Acta
, vol.1459
, pp. 230-238
-
-
Djafarzadeh, R.1
Kerscher, S.2
Zwicker, K.3
Radermacher, M.4
Lindahl, M.5
Schägger, H.6
Brandt, U.7
-
14
-
-
0037452914
-
Isolation, characterization and electron microscopic single particle analysis of the NADH:ubiquinone oxidoreductase (complex I) from the hyperthermophilic eubacterium Aquifex aeolicus
-
Peng G., Fritzsch G., Zickermann V., Schägger H., Mentele R., Lottspeich F., Bostina M., Radermacher M., Huber R., Stetter K.O., Michel H. Isolation, characterization and electron microscopic single particle analysis of the NADH:ubiquinone oxidoreductase (complex I) from the hyperthermophilic eubacterium Aquifex aeolicus. Biochemistry 2003, 42:3032-3039.
-
(2003)
Biochemistry
, vol.42
, pp. 3032-3039
-
-
Peng, G.1
Fritzsch, G.2
Zickermann, V.3
Schägger, H.4
Mentele, R.5
Lottspeich, F.6
Bostina, M.7
Radermacher, M.8
Huber, R.9
Stetter, K.O.10
Michel, H.11
-
15
-
-
33646678212
-
The three-dimensional structure of complex I from Yarrowia lipolytica: a highly dynamic enzyme
-
Radermacher M., Ruiz T., Clason T., Benjamin S., Brandt U., Zickermann V. The three-dimensional structure of complex I from Yarrowia lipolytica: a highly dynamic enzyme. J. Struct. Biol. 2006, 154:269-279.
-
(2006)
J. Struct. Biol.
, vol.154
, pp. 269-279
-
-
Radermacher, M.1
Ruiz, T.2
Clason, T.3
Benjamin, S.4
Brandt, U.5
Zickermann, V.6
-
16
-
-
46349107838
-
Three-dimensional structure of respiratory complex I from Escherichia coli in ice in the presence of nucleotides
-
Morgan D.J., Sazanov L.A. Three-dimensional structure of respiratory complex I from Escherichia coli in ice in the presence of nucleotides. Biochim. Biophys. Acta 2008, 1777:711-718.
-
(2008)
Biochim. Biophys. Acta
, vol.1777
, pp. 711-718
-
-
Morgan, D.J.1
Sazanov, L.A.2
-
17
-
-
72449176842
-
The structure of eukaryotic and prokaryotic complex I
-
Clason T., Ruiz T., Schagger H., Peng G., Zickermann V., Brandt U., Michel H., Radermacher M. The structure of eukaryotic and prokaryotic complex I. J. Struct. Biol. 2010, 169:81-88.
-
(2010)
J. Struct. Biol.
, vol.169
, pp. 81-88
-
-
Clason, T.1
Ruiz, T.2
Schagger, H.3
Peng, G.4
Zickermann, V.5
Brandt, U.6
Michel, H.7
Radermacher, M.8
-
18
-
-
0026472383
-
Resolution of NADH:ubiquinone oxidoreductase from bovine heart mitochondria into two subcomplexes, one of which contains the redox centers of the enzyme
-
Finel M., Skehel J.M., Albracht S.P.J., Fearnley I.M., Walker J.E. Resolution of NADH:ubiquinone oxidoreductase from bovine heart mitochondria into two subcomplexes, one of which contains the redox centers of the enzyme. Biochemistry 1992, 31:11425-11434.
-
(1992)
Biochemistry
, vol.31
, pp. 11425-11434
-
-
Finel, M.1
Skehel, J.M.2
Albracht, S.P.J.3
Fearnley, I.M.4
Walker, J.E.5
-
19
-
-
0032490089
-
Iron-sulfur clusters semiquinones in complex I
-
Ohnishi T. Iron-sulfur clusters semiquinones in complex I. Biochim. Biophys. Acta 1998, 1364:186-206.
-
(1998)
Biochim. Biophys. Acta
, vol.1364
, pp. 186-206
-
-
Ohnishi, T.1
-
20
-
-
0035918512
-
Identification of two tetranuclear FeS clusters on the ferredoxin-type subunit of NADH:ubiquinone oxidoreductase (complex I)
-
Rasmussen T., Scheide D., Brors B., Kintscher L., Weiss H., Friedrich T. Identification of two tetranuclear FeS clusters on the ferredoxin-type subunit of NADH:ubiquinone oxidoreductase (complex I). Biochemistry 2001, 40:6124-6131.
-
(2001)
Biochemistry
, vol.40
, pp. 6124-6131
-
-
Rasmussen, T.1
Scheide, D.2
Brors, B.3
Kintscher, L.4
Weiss, H.5
Friedrich, T.6
-
21
-
-
23044477952
-
Organization of iron-sulfur clusters in respiratory complex I
-
Hinchliffe P., Sazanov L.A. Organization of iron-sulfur clusters in respiratory complex I. Science 2005, 309:771-774.
-
(2005)
Science
, vol.309
, pp. 771-774
-
-
Hinchliffe, P.1
Sazanov, L.A.2
-
22
-
-
33644872938
-
Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
-
Sazanov L.A., Hinchliffe P. Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus. Science 2006, 311:1430-1436.
-
(2006)
Science
, vol.311
, pp. 1430-1436
-
-
Sazanov, L.A.1
Hinchliffe, P.2
-
23
-
-
33750804123
-
Definition of the mitochondrial proteome by measurement of molecular masses of membrane proteins
-
Carroll J., Fearnley I.M., Walker J.E. Definition of the mitochondrial proteome by measurement of molecular masses of membrane proteins. Proc. Natl. Acad. Sci. USA 2006, 103:16170-16175.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 16170-16175
-
-
Carroll, J.1
Fearnley, I.M.2
Walker, J.E.3
-
24
-
-
0026484793
-
Conservation of sequences of subunits of mitochondrial complex I and their relationships with other proteins
-
(Review)
-
Fearnley I.M., Walker J.E. Conservation of sequences of subunits of mitochondrial complex I and their relationships with other proteins. Biochim. Biophys. Acta 1992, 1140:105-134. (Review).
-
(1992)
Biochim. Biophys. Acta
, vol.1140
, pp. 105-134
-
-
Fearnley, I.M.1
Walker, J.E.2
-
25
-
-
0031582715
-
Modular evolution of the respiratory NADH:Ubiquinone oxidoreductase and the origin of its modules
-
Friedrich T., Weiss H. Modular evolution of the respiratory NADH:Ubiquinone oxidoreductase and the origin of its modules. J. Theor. Biol. 1997, 187:529-540.
-
(1997)
J. Theor. Biol.
, vol.187
, pp. 529-540
-
-
Friedrich, T.1
Weiss, H.2
-
26
-
-
0034782745
-
Complex I: a chimaera of a redox and conformation-driven proton pump?
-
Friedrich T. Complex I: a chimaera of a redox and conformation-driven proton pump?. J. Bioenerg. Biomembr. 2001, 33:169-177.
-
(2001)
J. Bioenerg. Biomembr.
, vol.33
, pp. 169-177
-
-
Friedrich, T.1
-
27
-
-
0037010862
-
Transmembrane topology of the NuoL, M and N subunits of NADH: quinone oxidoreductase and their homologues among membrane- bound hydrogenases and bona fide antiporters
-
Mathiesen C., Hagerhall C. Transmembrane topology of the NuoL, M and N subunits of NADH: quinone oxidoreductase and their homologues among membrane- bound hydrogenases and bona fide antiporters. Biochim. Biophys. Acta 2002, 1556:121-132.
-
(2002)
Biochim. Biophys. Acta
, vol.1556
, pp. 121-132
-
-
Mathiesen, C.1
Hagerhall, C.2
-
28
-
-
0041563699
-
The 'antiporter module' of respiratory chain complex I includes the MrpC/NuoK subunit - a revision of the modular evolution scheme
-
Mathiesen C., Hagerhall C. The 'antiporter module' of respiratory chain complex I includes the MrpC/NuoK subunit - a revision of the modular evolution scheme. FEBS Lett. 2003, 549:7-13.
-
(2003)
FEBS Lett.
, vol.549
, pp. 7-13
-
-
Mathiesen, C.1
Hagerhall, C.2
-
29
-
-
0034665878
-
Cryo-electron crystallography of two sub-complexes of bovine complex I reveals the relationship beween the membrane and peripheral arms
-
Sazanov L.A., Walker J.E. Cryo-electron crystallography of two sub-complexes of bovine complex I reveals the relationship beween the membrane and peripheral arms. J. Mol. Biol. 2000, 392:455-464.
-
(2000)
J. Mol. Biol.
, vol.392
, pp. 455-464
-
-
Sazanov, L.A.1
Walker, J.E.2
-
30
-
-
0036304765
-
Impact of mutations affecting ND mitochondria-encoded subunits on the activity and assembly of complex I in chlamydomonas. Implication for the structural organization of the enzyme
-
Cardol P., Matagne R.F., Remacle C. Impact of mutations affecting ND mitochondria-encoded subunits on the activity and assembly of complex I in chlamydomonas. Implication for the structural organization of the enzyme. J. Mol. Biol. 2002, 319:1211-1221.
-
(2002)
J. Mol. Biol.
, vol.319
, pp. 1211-1221
-
-
Cardol, P.1
Matagne, R.F.2
Remacle, C.3
-
31
-
-
0242322000
-
The location of NuoL and NuoM subunits in the membrane domain of the Escherichia coli complex I - Implications for the mechanism of proton pumping
-
Holt P.J., Morgan D.J., Sazanov L.A. The location of NuoL and NuoM subunits in the membrane domain of the Escherichia coli complex I - Implications for the mechanism of proton pumping. J. Biol. Chem. 2003, 278:43114-43120.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 43114-43120
-
-
Holt, P.J.1
Morgan, D.J.2
Sazanov, L.A.3
-
32
-
-
34547096741
-
Single particle analysis confirms distal location of subunits NuoL and NuoM in Escherichia coli complex I
-
Baranova E.A., Morgan D.J., Sazanov L.A. Single particle analysis confirms distal location of subunits NuoL and NuoM in Escherichia coli complex I. J. Struct. Biol. 2007, 159:238-242.
-
(2007)
J. Struct. Biol.
, vol.159
, pp. 238-242
-
-
Baranova, E.A.1
Morgan, D.J.2
Sazanov, L.A.3
-
33
-
-
0021769852
-
Two protons are pumped from the mitochondrial matrix per electron transferred between NADH and ubiquinone
-
Wikström M.K.F. Two protons are pumped from the mitochondrial matrix per electron transferred between NADH and ubiquinone. FEBS Lett. 1984, 169:300-304.
-
(1984)
FEBS Lett.
, vol.169
, pp. 300-304
-
-
Wikström, M.K.F.1
-
34
-
-
0032588194
-
- stoichiometry in NADH-quinone reductase reactions catalyzed by bovine heart submitochondrial particles
-
- stoichiometry in NADH-quinone reductase reactions catalyzed by bovine heart submitochondrial particles. FEBS Lett. 1999, 451:157-161.
-
(1999)
FEBS Lett.
, vol.451
, pp. 157-161
-
-
Galkin, A.S.1
Grivennikova, V.G.2
Vinogradov, A.D.3
-
35
-
-
33751556659
-
The proton pumping stoichiometry of purifiedmitochondrial complex I reconstituted into proteoliposomes
-
Galkin A., Dröse S., Brandt U. The proton pumping stoichiometry of purifiedmitochondrial complex I reconstituted into proteoliposomes. Biochim. Biophys. Acta 2006, 1757:1575-1581.
-
(2006)
Biochim. Biophys. Acta
, vol.1757
, pp. 1575-1581
-
-
Galkin, A.1
Dröse, S.2
Brandt, U.3
-
36
-
-
0032490104
-
Catalytic properties of the mitochondrial NADH-ubiquinone oxidoreductase (complex I) and the pseudo-reversible active/inactive enzyme transition
-
Vinogradov A.D. Catalytic properties of the mitochondrial NADH-ubiquinone oxidoreductase (complex I) and the pseudo-reversible active/inactive enzyme transition. Biochim. Biophys. Acta 1998, 1364:169-185.
-
(1998)
Biochim. Biophys. Acta
, vol.1364
, pp. 169-185
-
-
Vinogradov, A.D.1
-
37
-
-
34548361908
-
Direct localization of the 51 and 24kDa subunits of mitochondrial complex I by three-dimensional difference imaging
-
Clason T., Zickermann V., Ruiz T., Brandt U., Radermacher M. Direct localization of the 51 and 24kDa subunits of mitochondrial complex I by three-dimensional difference imaging. J. Struct. Biol. 2007, 159:433-442.
-
(2007)
J. Struct. Biol.
, vol.159
, pp. 433-442
-
-
Clason, T.1
Zickermann, V.2
Ruiz, T.3
Brandt, U.4
Radermacher, M.5
-
38
-
-
0032490103
-
A reductant-induced oxidation mechanism for complex I
-
Dutton P.L., Moser C.C., Sled V.D., Daldal F., Ohnishi T. A reductant-induced oxidation mechanism for complex I. Biochim. Biophys. Acta 1998, 1364:245-257.
-
(1998)
Biochim. Biophys. Acta
, vol.1364
, pp. 245-257
-
-
Dutton, P.L.1
Moser, C.C.2
Sled, V.D.3
Daldal, F.4
Ohnishi, T.5
-
39
-
-
0033000256
-
Proton translocation in the respiratory chain involving ubiquinone - A hypothetical semiquinone switch mechanism for complex I
-
Brandt U. Proton translocation in the respiratory chain involving ubiquinone - A hypothetical semiquinone switch mechanism for complex I. Biofactors 1999, 9:95-101.
-
(1999)
Biofactors
, vol.9
, pp. 95-101
-
-
Brandt, U.1
-
40
-
-
0035471020
-
Respiratory complex I: structure, redox components, and possible mechanisms of energy transduction
-
Vinogradov A.D. Respiratory complex I: structure, redox components, and possible mechanisms of energy transduction. Biochemistry-Moscow 2001, 66:1086-1097.
-
(2001)
Biochemistry-Moscow
, vol.66
, pp. 1086-1097
-
-
Vinogradov, A.D.1
-
41
-
-
0038392255
-
Proton pumping by NADH:ubiquinone oxidoreductase. A redox driven conformational change mechanism?
-
Brandt U., Kerscher S., Dröse S., Zwicker K., Zickermann V. Proton pumping by NADH:ubiquinone oxidoreductase. A redox driven conformational change mechanism?. FEBS Lett. 2003, 545:9-17.
-
(2003)
FEBS Lett.
, vol.545
, pp. 9-17
-
-
Brandt, U.1
Kerscher, S.2
Dröse, S.3
Zwicker, K.4
Zickermann, V.5
-
42
-
-
24044481623
-
Conformation-driven and semiquinone-gated proton-pump mechanism in the NADH-ubiquinone oxidoreductase (complex I)
-
Ohnishi T., Salerno J.C. Conformation-driven and semiquinone-gated proton-pump mechanism in the NADH-ubiquinone oxidoreductase (complex I). FEBS Lett. 2005, 579:4555-4561.
-
(2005)
FEBS Lett.
, vol.579
, pp. 4555-4561
-
-
Ohnishi, T.1
Salerno, J.C.2
-
43
-
-
21044445453
-
Energy transduction by respiratory complex I - an evaluation of current knowledge
-
Hirst J. Energy transduction by respiratory complex I - an evaluation of current knowledge. Biochem. Soc. Trans. 2005, 33:525-529.
-
(2005)
Biochem. Soc. Trans.
, vol.33
, pp. 525-529
-
-
Hirst, J.1
-
44
-
-
33744471394
-
A possible role for iron-sulfur cluster N2 in proton translocation by the NADH: ubiquinone oxidoreductase (complex I)
-
Flemming D., Stolpe S., Schneider D., Hellwig P., Friedrich T. A possible role for iron-sulfur cluster N2 in proton translocation by the NADH: ubiquinone oxidoreductase (complex I). J. Mol. Microbiol. Biotechnol. 2005, 10:222.
-
(2005)
J. Mol. Microbiol. Biotechnol.
, vol.10
, pp. 222
-
-
Flemming, D.1
Stolpe, S.2
Schneider, D.3
Hellwig, P.4
Friedrich, T.5
-
45
-
-
49349107465
-
Conserved lysine residues of the membrane subunit NuoM are involved in energy conversion by the proton-pumping NADH:ubiquinone oxidoreductase (complex I)
-
Euro L., Belevich G., Verkhovsky M.I., Wikström M., Verkhovskaya M. Conserved lysine residues of the membrane subunit NuoM are involved in energy conversion by the proton-pumping NADH:ubiquinone oxidoreductase (complex I). Biochim. Biophys. Acta 2008, 1777:1166-1172.
-
(2008)
Biochim. Biophys. Acta
, vol.1777
, pp. 1166-1172
-
-
Euro, L.1
Belevich, G.2
Verkhovsky, M.I.3
Wikström, M.4
Verkhovskaya, M.5
-
46
-
-
70350351403
-
Structural basis for the mechanism of respiratory complex I
-
Berrisford J.M., Sazanov L.A. Structural basis for the mechanism of respiratory complex I. J. Biol. Chem. 2009, 284:29773-29783.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 29773-29783
-
-
Berrisford, J.M.1
Sazanov, L.A.2
-
47
-
-
0031033436
-
Proton-translocation by membrane-bound NADH:ubiquinone-oxidoreductase (complex I) through redox-gated ligand conduction
-
Brandt U. Proton-translocation by membrane-bound NADH:ubiquinone-oxidoreductase (complex I) through redox-gated ligand conduction. Biochim. Biophys. Acta 1997, 1318:79-91.
-
(1997)
Biochim. Biophys. Acta
, vol.1318
, pp. 79-91
-
-
Brandt, U.1
-
48
-
-
33749184515
-
Electron tunneling chains of mitochondria
-
Moser C.C., Farid T.A., Chobot S.E., Dutton P.L. Electron tunneling chains of mitochondria. Biochim. Biophys. Acta-Bioenerg. 2006, 1757:1096-1109.
-
(2006)
Biochim. Biophys. Acta-Bioenerg.
, vol.1757
, pp. 1096-1109
-
-
Moser, C.C.1
Farid, T.A.2
Chobot, S.E.3
Dutton, P.L.4
-
49
-
-
41649119007
-
Real-time electron transfer in respiratory complex I
-
Verkhovskaya M.L., Belevich N., Euro L., Wikström M., Verkhovsky M.I. Real-time electron transfer in respiratory complex I. Proc. Natl. Acad. Sci. USA 2008, 105:3763-3767.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 3763-3767
-
-
Verkhovskaya, M.L.1
Belevich, N.2
Euro, L.3
Wikström, M.4
Verkhovsky, M.I.5
-
50
-
-
33747370385
-
The redox-Bohr group associated with iron-sulfur cluster N2 of complex I
-
Zwicker K., Galkin A., Dröse S., Grgic L., Kerscher S., Brandt U. The redox-Bohr group associated with iron-sulfur cluster N2 of complex I. J. Biol. Chem. 2006, 281:23013-23017.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 23013-23017
-
-
Zwicker, K.1
Galkin, A.2
Dröse, S.3
Grgic, L.4
Kerscher, S.5
Brandt, U.6
-
51
-
-
33845750131
-
Investigation of the mechanism of proton translocation by NADH: ubiquinone oxidoreductase (complex I) from bovine heart mitochondria: does the enzyme operate by a Q-cycle mechanism?
-
Sherwood S., Hirst J. Investigation of the mechanism of proton translocation by NADH: ubiquinone oxidoreductase (complex I) from bovine heart mitochondria: does the enzyme operate by a Q-cycle mechanism?. Biochem. J. 2006, 400:541-550.
-
(2006)
Biochem. J.
, vol.400
, pp. 541-550
-
-
Sherwood, S.1
Hirst, J.2
-
52
-
-
0035968167
-
A central functional role for the 49-kDa subunit within the catalytic core of mitochondrial complex I
-
Kashani-Poor N., Zwicker K., Kerscher S., Brandt U. A central functional role for the 49-kDa subunit within the catalytic core of mitochondrial complex I. J. Biol. Chem. 2001, 276:24082-24087.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 24082-24087
-
-
Kashani-Poor, N.1
Zwicker, K.2
Kerscher, S.3
Brandt, U.4
-
53
-
-
0034773225
-
Exploring the catalytic core of complex I by Yarrowia lipolytica yeast genetics
-
Kerscher S., Kashani-Poor N., Zwicker K., Zickermann V., Brandt U. Exploring the catalytic core of complex I by Yarrowia lipolytica yeast genetics. J. Bioenerg. Biomembr. 2001, 33:187-196.
-
(2001)
J. Bioenerg. Biomembr.
, vol.33
, pp. 187-196
-
-
Kerscher, S.1
Kashani-Poor, N.2
Zwicker, K.3
Zickermann, V.4
Brandt, U.5
-
54
-
-
0025157053
-
Nucleotide sequence and expression of an operon in Escherichia coli coding for formate hydrogenlyase components
-
Böhm R., Sauter M., Böck A. Nucleotide sequence and expression of an operon in Escherichia coli coding for formate hydrogenlyase components. Mol. Microbiol. 1990, 4:231-243.
-
(1990)
Mol. Microbiol.
, vol.4
, pp. 231-243
-
-
Böhm, R.1
Sauter, M.2
Böck, A.3
-
55
-
-
0027328631
-
Intimate relationships of the large and the small subunits of all nickel hydrogenases with two nuclear-encoded subunits of mitochondrial NADH:ubiquinone oxidoreductase
-
Albracht S.P.J. Intimate relationships of the large and the small subunits of all nickel hydrogenases with two nuclear-encoded subunits of mitochondrial NADH:ubiquinone oxidoreductase. Biochim. Biophys. Acta 1993, 1144:221-224.
-
(1993)
Biochim. Biophys. Acta
, vol.1144
, pp. 221-224
-
-
Albracht, S.P.J.1
-
56
-
-
0030929780
-
Genetic evidence for the existence of two quinone related inhibitor binding sites in NADH-CoQ reductase
-
Darrouzet E., Dupuis A. Genetic evidence for the existence of two quinone related inhibitor binding sites in NADH-CoQ reductase. Biochim. Biophys. Acta 1997, 1319:1-4.
-
(1997)
Biochim. Biophys. Acta
, vol.1319
, pp. 1-4
-
-
Darrouzet, E.1
Dupuis, A.2
-
57
-
-
0032504107
-
The 49-kDa subunit of NADH-ubiquinone oxidoreductase (complex I) is involved in the binding of piericidin and rotenone, two quinone-related inhibitors
-
Darrouzet E., Issartel J.P., Lunardi J., Dupuis A. The 49-kDa subunit of NADH-ubiquinone oxidoreductase (complex I) is involved in the binding of piericidin and rotenone, two quinone-related inhibitors. FEBS Lett. 1998, 431:34-38.
-
(1998)
FEBS Lett.
, vol.431
, pp. 34-38
-
-
Darrouzet, E.1
Issartel, J.P.2
Lunardi, J.3
Dupuis, A.4
-
58
-
-
0035795163
-
Evidence for a quinone binding site close to the interface between NUOD and NUOB subunits of complex I
-
Prieur I., Lunardi J., Dupuis A. Evidence for a quinone binding site close to the interface between NUOD and NUOB subunits of complex I. Biochim. Biophys. Acta 2001, 1504:173-178.
-
(2001)
Biochim. Biophys. Acta
, vol.1504
, pp. 173-178
-
-
Prieur, I.1
Lunardi, J.2
Dupuis, A.3
-
59
-
-
0035132188
-
Mutations in the complex I NDUFS2 gene of patients with cardiomyopathy and encephalomyopathy
-
Loeffen J., Elpeleg O., Smeitink J., Smeets R., Stöckler-Ipsiroglu S., Mandel H., Sengers R., Trijbels F., Van den Heuvel L. Mutations in the complex I NDUFS2 gene of patients with cardiomyopathy and encephalomyopathy. Ann. Neurol. 2001, 49:195-201.
-
(2001)
Ann. Neurol.
, vol.49
, pp. 195-201
-
-
Loeffen, J.1
Elpeleg, O.2
Smeitink, J.3
Smeets, R.4
Stöckler-Ipsiroglu, S.5
Mandel, H.6
Sengers, R.7
Trijbels, F.8
Van den Heuvel, L.9
-
60
-
-
3042670809
-
Molecular characterization of benzimidazole resistance in Helicobacter pylori
-
Mills S.D., Yang W., McCormack K. Molecular characterization of benzimidazole resistance in Helicobacter pylori. Antimicrob. Agents Chemother. 2004, 48:2524-2530.
-
(2004)
Antimicrob. Agents Chemother.
, vol.48
, pp. 2524-2530
-
-
Mills, S.D.1
Yang, W.2
McCormack, K.3
-
61
-
-
0033616791
-
NADH-quinone oxidoreductase: PSST subunit couples electron transfer from iron-sulfur cluster N2 to quinone
-
Schuler F., Yano T., Di Bernardo S., Yagi T., Yankovskaya V., Singer T.P., Casida J.E. NADH-quinone oxidoreductase: PSST subunit couples electron transfer from iron-sulfur cluster N2 to quinone. Proc. Natl. Acad. Sci. USA 1999, 96:4149-4153.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4149-4153
-
-
Schuler, F.1
Yano, T.2
Di Bernardo, S.3
Yagi, T.4
Yankovskaya, V.5
Singer, T.P.6
Casida, J.E.7
-
62
-
-
2442701768
-
Functional significance of conserved histidines and arginines in the 49kDa subunit of mitochondrial complex I
-
Grgic L., Zwicker K., Kashani-Poor N., Kerscher S., Brandt U. Functional significance of conserved histidines and arginines in the 49kDa subunit of mitochondrial complex I. J. Biol. Chem. 2004, 279:21193-21199.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 21193-21199
-
-
Grgic, L.1
Zwicker, K.2
Kashani-Poor, N.3
Kerscher, S.4
Brandt, U.5
-
63
-
-
33646367939
-
Insights into the mechanism of mitochondrial complex I from its distant relatives, the [NiFe] hydrogenases
-
RSC Publishing, Cambridge, M. Wikstrom (Ed.)
-
Kerscher S., Zickermann V., Zwicker K., Brandt U. Insights into the mechanism of mitochondrial complex I from its distant relatives, the [NiFe] hydrogenases. Biophysical and Structural Aspects of Bioenergetics 2005, 156-184. RSC Publishing, Cambridge. M. Wikstrom (Ed.).
-
(2005)
Biophysical and Structural Aspects of Bioenergetics
, pp. 156-184
-
-
Kerscher, S.1
Zickermann, V.2
Zwicker, K.3
Brandt, U.4
-
64
-
-
53249107720
-
Synthesis and characterization of new piperazine-type inhibitors for mitochondrial NADH-ubiquinone oxidoreductase (complex I)
-
Ichimaru N., Murai M., Kakutani N., Kako J., Ishihara A., Nakagawa Y., Nishioka T., Yagi T., Miyoshi H. Synthesis and characterization of new piperazine-type inhibitors for mitochondrial NADH-ubiquinone oxidoreductase (complex I). Biochemistry 2008, 47:10816-10826.
-
(2008)
Biochemistry
, vol.47
, pp. 10816-10826
-
-
Ichimaru, N.1
Murai, M.2
Kakutani, N.3
Kako, J.4
Ishihara, A.5
Nakagawa, Y.6
Nishioka, T.7
Yagi, T.8
Miyoshi, H.9
-
65
-
-
35748979985
-
Exploring the ubiquinone binding cavity of respiratory complex I
-
Tocilescu M.A., Fendel U., Zwicker K., Kerscher S., Brandt U. Exploring the ubiquinone binding cavity of respiratory complex I. J. Biol. Chem. 2007, 282:29514-29520.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 29514-29520
-
-
Tocilescu, M.A.1
Fendel, U.2
Zwicker, K.3
Kerscher, S.4
Brandt, U.5
-
66
-
-
77953811928
-
The role of a conserved tyrosine in the 49-kDa subunit of complex I for ubiquinone binding and reduction
-
Tocilescu M.A., Fendel U., Zwicker K., Dröse S., Kerscher S., Brandt U. The role of a conserved tyrosine in the 49-kDa subunit of complex I for ubiquinone binding and reduction. Biochim. Biophys. Acta Bioenerg. 2010, 1797:625-632.
-
(2010)
Biochim. Biophys. Acta Bioenerg.
, vol.1797
, pp. 625-632
-
-
Tocilescu, M.A.1
Fendel, U.2
Zwicker, K.3
Dröse, S.4
Kerscher, S.5
Brandt, U.6
-
67
-
-
0032573198
-
Role of the isoprenyl tail of ubiquinone in reaction with respiratory enzymes: studies with bovine heart mitochondrial complex I and Escherichia coli bo-type ubiquinol oxidase
-
Sakamoto K., Miyoshi H., Ohshima M., Kuwabara K., Kano K., Akagi T., Mogi T., Iwamura H. Role of the isoprenyl tail of ubiquinone in reaction with respiratory enzymes: studies with bovine heart mitochondrial complex I and Escherichia coli bo-type ubiquinol oxidase. Biochemistry 1998, 37:15106-15113.
-
(1998)
Biochemistry
, vol.37
, pp. 15106-15113
-
-
Sakamoto, K.1
Miyoshi, H.2
Ohshima, M.3
Kuwabara, K.4
Kano, K.5
Akagi, T.6
Mogi, T.7
Iwamura, H.8
-
68
-
-
33748343422
-
Darwin at the molecular scale: selection and variance in electron tunnelling proteins including cytochrome c oxidase
-
Moser C.C., Page C.C., Dutton P.L. Darwin at the molecular scale: selection and variance in electron tunnelling proteins including cytochrome c oxidase. Philos. Trans. R. Soc. B-Biol. Sci. 2006, 361:1295-1305.
-
(2006)
Philos. Trans. R. Soc. B-Biol. Sci.
, vol.361
, pp. 1295-1305
-
-
Moser, C.C.1
Page, C.C.2
Dutton, P.L.3
-
69
-
-
0142149098
-
Two aspartic acid residues in the PSST-homologous NUKM subunit of complex I from Yarrowia lipolytica are essential for catalytic activity
-
Garofano A., Zwicker K., Kerscher S., Okun P., Brandt U. Two aspartic acid residues in the PSST-homologous NUKM subunit of complex I from Yarrowia lipolytica are essential for catalytic activity. J. Biol. Chem. 2003, 278:42435-42440.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 42435-42440
-
-
Garofano, A.1
Zwicker, K.2
Kerscher, S.3
Okun, P.4
Brandt, U.5
-
70
-
-
0034604568
-
Function of conserved acidic residues in the PSST-homologue of complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica
-
Ahlers P., Zwicker K., Kerscher S., Brandt U. Function of conserved acidic residues in the PSST-homologue of complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica. J. Biol. Chem. 2000, 275:23577-23582.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23577-23582
-
-
Ahlers, P.1
Zwicker, K.2
Kerscher, S.3
Brandt, U.4
-
71
-
-
1642392110
-
Subunit proximity in the H+-translocating NADH-quinone oxidoreductase probed by zero-length cross-linking
-
Kao M.C., Matsuno-Yagi A., Yagi T. Subunit proximity in the H+-translocating NADH-quinone oxidoreductase probed by zero-length cross-linking. Biochemistry 2004, 43:3750-3755.
-
(2004)
Biochemistry
, vol.43
, pp. 3750-3755
-
-
Kao, M.C.1
Matsuno-Yagi, A.2
Yagi, T.3
-
72
-
-
65649153703
-
Critical Roles of Subunit NuoH (ND1) in the Assembly of Peripheral Subunits with the Membrane Domain of Escherichia coli NDH-1
-
Sinha P.K., Torres-Bacete J., Nakamaru-Ogiso E., Castro-Guerrero N., Matsuno-Yagi A., Yagi T. Critical Roles of Subunit NuoH (ND1) in the Assembly of Peripheral Subunits with the Membrane Domain of Escherichia coli NDH-1. J. Biol. Chem. 2009, 284:9814-9823.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 9814-9823
-
-
Sinha, P.K.1
Torres-Bacete, J.2
Nakamaru-Ogiso, E.3
Castro-Guerrero, N.4
Matsuno-Yagi, A.5
Yagi, T.6
-
73
-
-
0021665043
-
Photoaffinity labelling of mitochondrial NADH dehydrogenase with arylazidoamorphigenin, an analogue of rotenone
-
Earley F.G., Ragan C.I. Photoaffinity labelling of mitochondrial NADH dehydrogenase with arylazidoamorphigenin, an analogue of rotenone. Biochem. J. 1984, 224:525-534.
-
(1984)
Biochem. J.
, vol.224
, pp. 525-534
-
-
Earley, F.G.1
Ragan, C.I.2
-
74
-
-
0023652658
-
Photolabelling of a mitochondrially encoded subunit of NADH dehydrogenase with [3H]dihydrorotenone
-
Earley F.G., Patel S.D., Ragan C.I., Attardi G. Photolabelling of a mitochondrially encoded subunit of NADH dehydrogenase with [3H]dihydrorotenone. FEBS Lett. 1987, 219:108-112.
-
(1987)
FEBS Lett.
, vol.219
, pp. 108-112
-
-
Earley, F.G.1
Patel, S.D.2
Ragan, C.I.3
Attardi, G.4
-
75
-
-
0023274011
-
Inhibition of NADH-ubiquinone reductase activity by N, N'-Dicyclohexylcarbodiimide and correlation of this inhibition with the occurrence of energy-coupling site 1 in various organisms
-
Yagi T. Inhibition of NADH-ubiquinone reductase activity by N, N'-Dicyclohexylcarbodiimide and correlation of this inhibition with the occurrence of energy-coupling site 1 in various organisms. Biochemistry 1987, 26:2822-2828.
-
(1987)
Biochemistry
, vol.26
, pp. 2822-2828
-
-
Yagi, T.1
-
76
-
-
0023724205
-
Identification of the dicyclohexylcarbodiimide-binding subunit of Nadh-ubiquinone oxidoreductase (complex-I)
-
Yagi T., Hatefi Y. Identification of the dicyclohexylcarbodiimide-binding subunit of Nadh-ubiquinone oxidoreductase (complex-I). J. Biol. Chem. 1988, 263:16150-16155.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 16150-16155
-
-
Yagi, T.1
Hatefi, Y.2
-
77
-
-
0027240373
-
Reaction of dicyclohexylcarbodiimide with mitochondrial proteins
-
Hassinen I.E., Vuokila P.T. Reaction of dicyclohexylcarbodiimide with mitochondrial proteins. Biochim. Biophys. Acta 1993, 1144:107-124.
-
(1993)
Biochim. Biophys. Acta
, vol.1144
, pp. 107-124
-
-
Hassinen, I.E.1
Vuokila, P.T.2
-
78
-
-
0035796952
-
Functional coupling of PSST and ND1 subunits in NADH: ubiquinone oxidoreductase established by photoaffinity labeling
-
Schuler F., Casida J.E. Functional coupling of PSST and ND1 subunits in NADH: ubiquinone oxidoreductase established by photoaffinity labeling. Biochim. Biophys. Acta 2001, 1506:79-87.
-
(2001)
Biochim. Biophys. Acta
, vol.1506
, pp. 79-87
-
-
Schuler, F.1
Casida, J.E.2
-
79
-
-
34249684873
-
The ND1 subunit constructs the inhibitor binding domain in bovine heart mitochondrial complex I
-
Murai M., Ishihara A., Nishioka T., Yagi T., Miyoshi H. The ND1 subunit constructs the inhibitor binding domain in bovine heart mitochondrial complex I. Biochemistry 2007, 46:6409-6416.
-
(2007)
Biochemistry
, vol.46
, pp. 6409-6416
-
-
Murai, M.1
Ishihara, A.2
Nishioka, T.3
Yagi, T.4
Miyoshi, H.5
-
80
-
-
60749121178
-
Characterization of the inhibitor binding site in mitochondrial NADH-ubiquinone oxidoreductase by photoaffinity labeling using a quinazoline-type inhibitor
-
Murai M., Sekiguchi K., Nishioka T., Miyoshi H. Characterization of the inhibitor binding site in mitochondrial NADH-ubiquinone oxidoreductase by photoaffinity labeling using a quinazoline-type inhibitor. Biochemistry 2009, 48:688-698.
-
(2009)
Biochemistry
, vol.48
, pp. 688-698
-
-
Murai, M.1
Sekiguchi, K.2
Nishioka, T.3
Miyoshi, H.4
-
81
-
-
67649494451
-
Exploring the binding site of acetogenin in the ND1 subunit of bovine mitochondrial complex I
-
Sekiguchi K., Murai M., Miyoshi H. Exploring the binding site of acetogenin in the ND1 subunit of bovine mitochondrial complex I. Biochim. Biophys. Acta 2009, 1787:1106-1111.
-
(2009)
Biochim. Biophys. Acta
, vol.1787
, pp. 1106-1111
-
-
Sekiguchi, K.1
Murai, M.2
Miyoshi, H.3
-
82
-
-
0032566316
-
Analysis of the pathogenic human mitochondrial mutation ND1/3460, and mutations of strictly conserved residues in its vicinity, using the bacterium Paracoccus denitrificans
-
Zickermann V., Barquera B., Wikström M.K.F., Finel M. Analysis of the pathogenic human mitochondrial mutation ND1/3460, and mutations of strictly conserved residues in its vicinity, using the bacterium Paracoccus denitrificans. Biochemistry 1998, 37:11792-11796.
-
(1998)
Biochemistry
, vol.37
, pp. 11792-11796
-
-
Zickermann, V.1
Barquera, B.2
Wikström, M.K.F.3
Finel, M.4
-
83
-
-
3142776181
-
Adjacent cysteines are capable of ligating the same tetranuclear iron-sulfur cluster
-
Gurrath M., Friedrich T. Adjacent cysteines are capable of ligating the same tetranuclear iron-sulfur cluster. Proteins 2004, 56:556-563.
-
(2004)
Proteins
, vol.56
, pp. 556-563
-
-
Gurrath, M.1
Friedrich, T.2
-
84
-
-
0036321770
-
EPR characterization of ubisemiquinones and iron-sulfur cluster N2, central components of the energy coupling in the NADH- ubiquinone oxidoreductase (complex I) in situ
-
Magnitsky S., Toulokhonova L., Yano T., Sled V.D., Hagerhall C., Grivennikova V.G., Burbaev D.S., Vinogradov A.D., Ohnishi T. EPR characterization of ubisemiquinones and iron-sulfur cluster N2, central components of the energy coupling in the NADH- ubiquinone oxidoreductase (complex I) in situ. J. Bioenerg. Biomembr. 2002, 34:193-208.
-
(2002)
J. Bioenerg. Biomembr.
, vol.34
, pp. 193-208
-
-
Magnitsky, S.1
Toulokhonova, L.2
Yano, T.3
Sled, V.D.4
Hagerhall, C.5
Grivennikova, V.G.6
Burbaev, D.S.7
Vinogradov, A.D.8
Ohnishi, T.9
-
85
-
-
0019324533
-
An analysis of some thermodynamic properties of iron-sulfur centres in site I of mitochondria
-
Ingledew W.J., Ohnishi T. An analysis of some thermodynamic properties of iron-sulfur centres in site I of mitochondria. Biochem. J. 1980, 186:111-117.
-
(1980)
Biochem. J.
, vol.186
, pp. 111-117
-
-
Ingledew, W.J.1
Ohnishi, T.2
-
86
-
-
0032490114
-
Inhibitors of NADH-ubiquinone reductase: an overview
-
Degli Esposti M. Inhibitors of NADH-ubiquinone reductase: an overview. Biochim. Biophys. Acta - Bioenerg. 1998, 1364:222-235.
-
(1998)
Biochim. Biophys. Acta - Bioenerg.
, vol.1364
, pp. 222-235
-
-
Degli Esposti, M.1
-
87
-
-
0032490106
-
Structure-activity relationships of some complex I inhibitors
-
Miyoshi H. Structure-activity relationships of some complex I inhibitors. Biochim. Biophys. Acta 1998, 1364:236-244.
-
(1998)
Biochim. Biophys. Acta
, vol.1364
, pp. 236-244
-
-
Miyoshi, H.1
-
88
-
-
0032490090
-
Complex I inhibitors as insecticides and acaricides
-
Lümmen P. Complex I inhibitors as insecticides and acaricides. Biochim. Biophys. Acta 1998, 1364:287-296.
-
(1998)
Biochim. Biophys. Acta
, vol.1364
, pp. 287-296
-
-
Lümmen, P.1
-
89
-
-
0032829920
-
Properties of the common inhibitor binding domain in mitochondrial NADH-dehydrogenase (complex I)
-
Okun J.G., Zickermann V., Brandt U. Properties of the common inhibitor binding domain in mitochondrial NADH-dehydrogenase (complex I). Biochem. Soc. Trans. 1999, 27:596-601.
-
(1999)
Biochem. Soc. Trans.
, vol.27
, pp. 596-601
-
-
Okun, J.G.1
Zickermann, V.2
Brandt, U.3
-
90
-
-
0032898050
-
Triton X-100 as a specific inhibitor of the mammalian NADH-ubiquinone oxidoreductase (complex I)
-
Ushakova A.V., Grivennikova V.G., Ohnishi T., Vinogradov A.D. Triton X-100 as a specific inhibitor of the mammalian NADH-ubiquinone oxidoreductase (complex I). Biochim. Biophys. Acta 1999, 1409:143-153.
-
(1999)
Biochim. Biophys. Acta
, vol.1409
, pp. 143-153
-
-
Ushakova, A.V.1
Grivennikova, V.G.2
Ohnishi, T.3
Vinogradov, A.D.4
-
91
-
-
0344820721
-
Three classes of inhibitors share a common binding domain in mitochondrial complex I (NADH:ubiquinone oxidoreductase)
-
Okun J.G., Lümmen P., Brandt U. Three classes of inhibitors share a common binding domain in mitochondrial complex I (NADH:ubiquinone oxidoreductase). J. Biol. Chem. 1999, 274:2625-2630.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 2625-2630
-
-
Okun, J.G.1
Lümmen, P.2
Brandt, U.3
-
92
-
-
0034691659
-
Binding of detergents and inhibitors to bovine complex I - A novel purification procedure of bovine complex I retaining full inhibitor sensitivity
-
Okun J.G., Zickermann V., Zwicker K., Schägger H., Brandt U. Binding of detergents and inhibitors to bovine complex I - A novel purification procedure of bovine complex I retaining full inhibitor sensitivity. Biochim. Biophys. Acta 2000, 1459:77-87.
-
(2000)
Biochim. Biophys. Acta
, vol.1459
, pp. 77-87
-
-
Okun, J.G.1
Zickermann, V.2
Zwicker, K.3
Schägger, H.4
Brandt, U.5
-
93
-
-
0021891869
-
The mitochondrial electron transport and oxidative phosphorylation system
-
Hatefi Y. The mitochondrial electron transport and oxidative phosphorylation system. Annu. Rev. Biochem. 1985, 54:1015-1069.
-
(1985)
Annu. Rev. Biochem.
, vol.54
, pp. 1015-1069
-
-
Hatefi, Y.1
-
94
-
-
0027976420
-
Two binding sites of inhibitors in NADH:ubiquinone oxidoreductase (complex I). - Relationship of one site with the ubiquinone-binding site of bacterial glucose:ubiquinone oxidoreductase
-
Friedrich T., van Heek P., Leif H., Ohnishi T., Forche E., Kunze B., Jansen R., Trowitzsch-Kienast W., Höfle G., Reichenbach H.X., Weiss H. Two binding sites of inhibitors in NADH:ubiquinone oxidoreductase (complex I). - Relationship of one site with the ubiquinone-binding site of bacterial glucose:ubiquinone oxidoreductase. Eur. J. Biochem. 1994, 219:691-698.
-
(1994)
Eur. J. Biochem.
, vol.219
, pp. 691-698
-
-
Friedrich, T.1
van Heek, P.2
Leif, H.3
Ohnishi, T.4
Forche, E.5
Kunze, B.6
Jansen, R.7
Trowitzsch-Kienast, W.8
Höfle, G.9
Reichenbach, H.X.10
Weiss, H.11
-
95
-
-
0028023673
-
The mechanism of proton and electron transport in mitochondrial complex I
-
Degli Esposti M., Ghelli A.X. The mechanism of proton and electron transport in mitochondrial complex I. Biochim. Biophys. Acta 1994, 1187:116-120.
-
(1994)
Biochim. Biophys. Acta
, vol.1187
, pp. 116-120
-
-
Degli Esposti, M.1
Ghelli, A.X.2
-
96
-
-
0030070202
-
Comparison of the inhibitory action of synthetic capsaicin analogues with various NADH-ubiquinone oxidoreductases
-
Satoh T., Miyoshi H., Sakamoto K., Iwamura H. Comparison of the inhibitory action of synthetic capsaicin analogues with various NADH-ubiquinone oxidoreductases. Biochim. Biophys. Acta 1996, 1273:21-30.
-
(1996)
Biochim. Biophys. Acta
, vol.1273
, pp. 21-30
-
-
Satoh, T.1
Miyoshi, H.2
Sakamoto, K.3
Iwamura, H.4
-
97
-
-
0033839954
-
Mitochondrial complex I: new insights from inhibitor assays
-
Estornell E. Mitochondrial complex I: new insights from inhibitor assays. Protoplasma 2000, 213:11-17.
-
(2000)
Protoplasma
, vol.213
, pp. 11-17
-
-
Estornell, E.1
-
98
-
-
0034765787
-
The insecticide target in the PSST subunit of complex I
-
Schuler F., Casida J.E. The insecticide target in the PSST subunit of complex I. Pest Manage. Sci. 2001, 57:932-940.
-
(2001)
Pest Manage. Sci.
, vol.57
, pp. 932-940
-
-
Schuler, F.1
Casida, J.E.2
-
99
-
-
0347295939
-
The ND5 subunit was labeled by a photoaffinity analogue of fenpyroximate in bovine mitochondrial complex I
-
Nakamaru-Ogiso E., Sakamoto K., Matsuno-Yagi A., Miyoshi H., Yagi T. The ND5 subunit was labeled by a photoaffinity analogue of fenpyroximate in bovine mitochondrial complex I. Biochemistry 2003, 42:746-754.
-
(2003)
Biochemistry
, vol.42
, pp. 746-754
-
-
Nakamaru-Ogiso, E.1
Sakamoto, K.2
Matsuno-Yagi, A.3
Miyoshi, H.4
Yagi, T.5
-
100
-
-
0030823106
-
Changes in mitochondrial complex I activity and coenzyme Q binding site in Leber's hereditary optic neuropathy (LHON)
-
Ghelli A.X., Degli Esposti M., Carelli V., Lenaz G. Changes in mitochondrial complex I activity and coenzyme Q binding site in Leber's hereditary optic neuropathy (LHON). Mol. Asp. Med. 1997, 18 (Supplement):s263-s267.
-
(1997)
Mol. Asp. Med.
-
-
Ghelli, A.X.1
Degli Esposti, M.2
Carelli, V.3
Lenaz, G.4
-
101
-
-
0029953887
-
Catalytic activity of complex I in cell lines that possess replacement mutations in the ND genes in Leber's hereditary optic neuropathy
-
Majander A., Finel M., Savontaus M.L., Nikoskelainen E., Wikström M.K.F. Catalytic activity of complex I in cell lines that possess replacement mutations in the ND genes in Leber's hereditary optic neuropathy. Eur. J. Biochem. 1996, 239:201-207.
-
(1996)
Eur. J. Biochem.
, vol.239
, pp. 201-207
-
-
Majander, A.1
Finel, M.2
Savontaus, M.L.3
Nikoskelainen, E.4
Wikström, M.K.F.5
-
102
-
-
0034619491
-
Mutagenesis of three conserved Glu residues in a bacterial homologue of the ND1 subunit of complex I affects ubiquinone reduction kinetics but not inhibition by dicyclohexylcarbodiimide
-
Kurki S., Zickermann V., Kervinen M., Hassinen I.E., Finel M. Mutagenesis of three conserved Glu residues in a bacterial homologue of the ND1 subunit of complex I affects ubiquinone reduction kinetics but not inhibition by dicyclohexylcarbodiimide. Biochemistry 2000, 39:13496-13502.
-
(2000)
Biochemistry
, vol.39
, pp. 13496-13502
-
-
Kurki, S.1
Zickermann, V.2
Kervinen, M.3
Hassinen, I.E.4
Finel, M.5
-
103
-
-
0027964504
-
Functional alterations of the mitochondrially encoded ND4 subunit associated with Leber's hereditary optic neuropathy
-
Degli Esposti M., Carelli V., Crimi M., Sangiorgi S., Montagna P., Lenaz G., Lugaresi E.X., Cortelli P. Functional alterations of the mitochondrially encoded ND4 subunit associated with Leber's hereditary optic neuropathy. FEBS Lett. 1994, 352:375-379.
-
(1994)
FEBS Lett.
, vol.352
, pp. 375-379
-
-
Degli Esposti, M.1
Carelli, V.2
Crimi, M.3
Sangiorgi, S.4
Montagna, P.5
Lenaz, G.6
Lugaresi, E.X.7
Cortelli, P.8
-
104
-
-
0030060823
-
Use of transmitochondrial cybrids to assign a complex I defect to the mitochondrial DNA-encoded NADH dehydrogenase subunit 6 gene mutation at nucleotide pair 14459 that causes Leber hereditary optic neuropathy and dystonia
-
Jun A.S., Trounce I.A., Brown M.D., Shoffner J.M., Wallace D.C. Use of transmitochondrial cybrids to assign a complex I defect to the mitochondrial DNA-encoded NADH dehydrogenase subunit 6 gene mutation at nucleotide pair 14459 that causes Leber hereditary optic neuropathy and dystonia. Mol. Cell. Biol. 1996, 16:771-777.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 771-777
-
-
Jun, A.S.1
Trounce, I.A.2
Brown, M.D.3
Shoffner, J.M.4
Wallace, D.C.5
-
105
-
-
0033028388
-
Biochemical features of mtDNA 14484 (ND6/M64V) point mutation associated with Leber's hereditary optic neuropathy
-
Carelli V., Ghelli A., Bucchi L., Montagna P., De Negri A., Leuzzi V., Carducci C., Lenaz G., Lugaresi E., Degli Esposti M. Biochemical features of mtDNA 14484 (ND6/M64V) point mutation associated with Leber's hereditary optic neuropathy. Ann. Neurol. 1999, 45:320-328.
-
(1999)
Ann. Neurol.
, vol.45
, pp. 320-328
-
-
Carelli, V.1
Ghelli, A.2
Bucchi, L.3
Montagna, P.4
De Negri, A.5
Leuzzi, V.6
Carducci, C.7
Lenaz, G.8
Lugaresi, E.9
Degli Esposti, M.10
-
106
-
-
38149079945
-
Leber hereditary optic neuropathy mutations in the ND6 subunit of mitochondrial complex I affect ubiquinone reduction kinetics in a bacterial model of the enzyme
-
Pätsi J., Kervinen M., Finel M., Hassinen I.E. Leber hereditary optic neuropathy mutations in the ND6 subunit of mitochondrial complex I affect ubiquinone reduction kinetics in a bacterial model of the enzyme. Biochem. J. 2008, 409:129-137.
-
(2008)
Biochem. J.
, vol.409
, pp. 129-137
-
-
Pätsi, J.1
Kervinen, M.2
Finel, M.3
Hassinen, I.E.4
-
107
-
-
0042767578
-
Characterization of inhibitor binding sites of mitochondrial complex I using fluorescent inhibitor
-
Ino T., Nishioka T., Miyoshi H. Characterization of inhibitor binding sites of mitochondrial complex I using fluorescent inhibitor. Biochim. Biophys. Acta 2003, 1605:15-20.
-
(2003)
Biochim. Biophys. Acta
, vol.1605
, pp. 15-20
-
-
Ino, T.1
Nishioka, T.2
Miyoshi, H.3
-
108
-
-
0037418550
-
The proton-translocating NADH-quinone oxidoreductase in the respiratory chain: the secret unlocked
-
Yagi T., Matsuno-Yagi A. The proton-translocating NADH-quinone oxidoreductase in the respiratory chain: the secret unlocked. Biochemistry 2003, 42:2266-2274.
-
(2003)
Biochemistry
, vol.42
, pp. 2266-2274
-
-
Yagi, T.1
Matsuno-Yagi, A.2
-
109
-
-
33644507467
-
Heterocyclic analogues of squamocin as inhibitors of mitochondrial complex I. On the role of the terminal lactone of annonaceous acetogenins
-
Duval R.A., Lewin G., Peris E., Chahboune N., Garofano A., Drose S., Cortes D., Brandt U., Hocquemiller R. Heterocyclic analogues of squamocin as inhibitors of mitochondrial complex I. On the role of the terminal lactone of annonaceous acetogenins. Biochemistry 2006.
-
(2006)
Biochemistry
-
-
Duval, R.A.1
Lewin, G.2
Peris, E.3
Chahboune, N.4
Garofano, A.5
Drose, S.6
Cortes, D.7
Brandt, U.8
Hocquemiller, R.9
-
110
-
-
78149464913
-
Current knowledge about the mechanism of energy transduction by respiratory complex I
-
RSC Publishing, Cambridge, M. Wikstrom (Ed.)
-
Hirst J. Current knowledge about the mechanism of energy transduction by respiratory complex I. Biophysical and structural aspects of bioenergetics 2005, 185-200. RSC Publishing, Cambridge. M. Wikstrom (Ed.).
-
(2005)
Biophysical and structural aspects of bioenergetics
, pp. 185-200
-
-
Hirst, J.1
-
111
-
-
50949091505
-
Exploring the inhibitor binding pocket of respiratory complex I
-
Fendel U., Tocilescu M.A., Kerscher S., Brandt U. Exploring the inhibitor binding pocket of respiratory complex I. Biochim. Biophys. Acta 2008, 1777:660-665.
-
(2008)
Biochim. Biophys. Acta
, vol.1777
, pp. 660-665
-
-
Fendel, U.1
Tocilescu, M.A.2
Kerscher, S.3
Brandt, U.4
-
112
-
-
13444259531
-
Nf) and the interaction with cluster N2: new insight into the energy-coupled electron transfer in complex I
-
Nf) and the interaction with cluster N2: new insight into the energy-coupled electron transfer in complex I. Biochemistry 2005, 44:1744-1754.
-
(2005)
Biochemistry
, vol.44
, pp. 1744-1754
-
-
Yano, T.1
Dunham, W.R.2
Ohnishi, T.3
-
113
-
-
0028214381
-
Ubisemiquinones as obligatory intermediates in the electron transfer from NADH to ubiquinone
-
de Jong A.M.P., Albracht S.P. Ubisemiquinones as obligatory intermediates in the electron transfer from NADH to ubiquinone. Eur. J. Biochem. 1994, 222:975-982.
-
(1994)
Eur. J. Biochem.
, vol.222
, pp. 975-982
-
-
de Jong, A.M.P.1
Albracht, S.P.2
-
114
-
-
0028984436
-
Energy-dependent complex I-associated ubisemiquinones in submitochondrial particles
-
Vinogradov A.D., Sled V.D., Burbaev D.S., Grivennikova V.G.X., Moroz I.A., Ohnishi T. Energy-dependent complex I-associated ubisemiquinones in submitochondrial particles. FEBS Lett. 1995, 370:83-87.
-
(1995)
FEBS Lett.
, vol.370
, pp. 83-87
-
-
Vinogradov, A.D.1
Sled, V.D.2
Burbaev, D.S.3
Grivennikova, V.G.X.4
Moroz, I.A.5
Ohnishi, T.6
-
115
-
-
11844287666
-
Thermodynamic and EPR studies of slowly relaxing ubisemiquinone species in the isolated bovine heart complex I
-
Ohnishi T., Johnson J.E., Yano T., LoBrutto R., Widger W.R. Thermodynamic and EPR studies of slowly relaxing ubisemiquinone species in the isolated bovine heart complex I. FEBS Lett. 2005, 579:500-506.
-
(2005)
FEBS Lett.
, vol.579
, pp. 500-506
-
-
Ohnishi, T.1
Johnson, J.E.2
Yano, T.3
LoBrutto, R.4
Widger, W.R.5
-
116
-
-
0027185319
-
Kinetics, control, and mechanism of ubiquinone reduction by the mammalian respiratory chain-linked NADH-ubiquinone reductase
-
Vinogradov A.D. Kinetics, control, and mechanism of ubiquinone reduction by the mammalian respiratory chain-linked NADH-ubiquinone reductase. J. Bioenerg. Biomembr. 1993, 25:367-374.
-
(1993)
J. Bioenerg. Biomembr.
, vol.25
, pp. 367-374
-
-
Vinogradov, A.D.1
-
117
-
-
0031046751
-
The iron-sulfur cluster 2 and ubisemiquinone radicals of NADH:ubiquinone oxidoreductase are involved in energy coupling in submitochondrial particles
-
van Belzen R., Kotlyar A.B., Moon N., Dunham W.R., Albracht S.P.J. The iron-sulfur cluster 2 and ubisemiquinone radicals of NADH:ubiquinone oxidoreductase are involved in energy coupling in submitochondrial particles. Biochemistry 1997, 36:886-893.
-
(1997)
Biochemistry
, vol.36
, pp. 886-893
-
-
van Belzen, R.1
Kotlyar, A.B.2
Moon, N.3
Dunham, W.R.4
Albracht, S.P.J.5
-
118
-
-
0037015686
-
Full recovery of the NADH:ubiquinone activity of complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica by the addition of phospholipids
-
Dröse S., Zwicker K., Brandt U. Full recovery of the NADH:ubiquinone activity of complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica by the addition of phospholipids. Biochim. Biophys. Acta 2002, 1556:65-72.
-
(2002)
Biochim. Biophys. Acta
, vol.1556
, pp. 65-72
-
-
Dröse, S.1
Zwicker, K.2
Brandt, U.3
-
119
-
-
0034598939
-
A motif for quinone binding sites in respiratory and photosynthetic systems
-
Fisher N., Rich P.R. A motif for quinone binding sites in respiratory and photosynthetic systems. J. Mol. Biol. 2000, 296:1153-1162.
-
(2000)
J. Mol. Biol.
, vol.296
, pp. 1153-1162
-
-
Fisher, N.1
Rich, P.R.2
-
120
-
-
0037815067
-
Ubiquinone-binding site in NADH:ubiquinone oxidoreductase from Escherichia coli
-
Gong X., Xie T., Yu L., Hesterberg M., Scheide D., Friedrich T., The C.-A.Yu. ubiquinone-binding site in NADH:ubiquinone oxidoreductase from Escherichia coli. J. Biol. Chem. 2003, 278:25731-25737.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 25731-25737
-
-
Gong, X.1
Xie, T.2
Yu, L.3
Hesterberg, M.4
Scheide, D.5
Friedrich, T.6
The, C.-A.7
-
121
-
-
0025299069
-
Small molecular mass ubiquinone-binding protein (QPc-9, 5kDa) in mitochondrial ubiquinol-cytochrome c reductase: isolation, ubiquinone-binding domain, and immunoinhibition
-
Usui S., Yu L., The C.-A.Yu. small molecular mass ubiquinone-binding protein (QPc-9, 5kDa) in mitochondrial ubiquinol-cytochrome c reductase: isolation, ubiquinone-binding domain, and immunoinhibition. Biochemistry 1990, 29:4618-4626.
-
(1990)
Biochemistry
, vol.29
, pp. 4618-4626
-
-
Usui, S.1
Yu, L.2
The, C.-A.3
-
122
-
-
37549049790
-
Characterization of the NuoM (ND4) subunit in Escherichia coli NDH-1 - Conserved charged residues essential for energy-coupled activities
-
Torres-Bacete J., Nakamaru-Ogiso E., Matsuno-Yagi A., Yagi T. Characterization of the NuoM (ND4) subunit in Escherichia coli NDH-1 - Conserved charged residues essential for energy-coupled activities. J. Biol. Chem. 2007, 282:36914-36922.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 36914-36922
-
-
Torres-Bacete, J.1
Nakamaru-Ogiso, E.2
Matsuno-Yagi, A.3
Yagi, T.4
-
123
-
-
0026489332
-
Identification of the ubiquinone-binding site of NADH: ubiquinone oxidoreductase (complex I) from Neurospora crassa
-
Heinrich H., Werner S. Identification of the ubiquinone-binding site of NADH: ubiquinone oxidoreductase (complex I) from Neurospora crassa. Biochemistry 1992, 31:11413-11419.
-
(1992)
Biochemistry
, vol.31
, pp. 11413-11419
-
-
Heinrich, H.1
Werner, S.2
-
124
-
-
0026486614
-
Characterization of the 9.5-kDA ubiquinone-binding protein of NADH: ubiquinone oxidoreductase (complex I) from Neurospora crassa
-
Heinrich H., Azeveda J.E., Werner S. Characterization of the 9.5-kDA ubiquinone-binding protein of NADH: ubiquinone oxidoreductase (complex I) from Neurospora crassa. Biochemistry 1992, 31:11420-11424.
-
(1992)
Biochemistry
, vol.31
, pp. 11420-11424
-
-
Heinrich, H.1
Azeveda, J.E.2
Werner, S.3
-
125
-
-
34247530881
-
Characterization of a subcomplex of mitochondrial NADH:ubiquinone oxidoreductase (complex I) lacking the flavoprotein part of the N-module
-
Zickermann V., Zwicker K., Tocilescu M.A., Kerscher S., Brandt U. Characterization of a subcomplex of mitochondrial NADH:ubiquinone oxidoreductase (complex I) lacking the flavoprotein part of the N-module. Biochim. Biophys. Acta 2007, 1767:393-400.
-
(2007)
Biochim. Biophys. Acta
, vol.1767
, pp. 393-400
-
-
Zickermann, V.1
Zwicker, K.2
Tocilescu, M.A.3
Kerscher, S.4
Brandt, U.5
-
126
-
-
0043208847
-
Functional implications from an unexpected position of the 49kDa subunit of complex I
-
Zickermann V., Bostina M., Hunte C., Ruiz T., Radermacher M., Brandt U. Functional implications from an unexpected position of the 49kDa subunit of complex I. J. Biol. Chem. 2003, 278:29072-29078.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 29072-29078
-
-
Zickermann, V.1
Bostina, M.2
Hunte, C.3
Ruiz, T.4
Radermacher, M.5
Brandt, U.6
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