Safrole-2',3'-oxide induces cytotoxic and genotoxic effects in HepG2 cells and in mice

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 726, Issue 2, 2011, Pages 234-241

  Chiang, Su yin ^a   Lee, Pei yi ^a   Lai, Ming tsung ^b,c   Shen, Li ching ^d   Chung, Wen sheng ^d   Huang, Hui fen ^a   Wu, Kuen yuh ^e   Wu, Hsiu ching ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

^e NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Comet assay; Genotoxicity; HepG2 cells; Micronucleus test; Peripheral blood; Safrole 2',3' oxide

Indexed keywords

SAFROLE; SAFROLE 2',3' OXIDE; UNCLASSIFIED DRUG;

ANGELICA SINENSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASARI RADIX; CELL STRAIN HEPG2; CHINESE MEDICINE; COMET ASSAY; CYTOKINESIS; CYTOTOXICITY; DNA STRAND BREAKAGE; GENOTOXICITY; HUMAN; HUMAN CELL; LEUKOCYTE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RETICULOCYTE;

ANIMALS; COMET ASSAY; DNA DAMAGE; HEP G2 CELLS; HUMANS; LEUKOCYTES; MALE; MICE; MICE, INBRED STRAINS; MICRONUCLEUS TESTS; MUTAGENS; SAFROLE;

ANGELICA SINENSIS; MAMMALIA; MUS; SASSAFRAS;

EID: 81055155923     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2011.09.014     Document Type: Article

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