Safrole oxide induces apoptosis by up-regulating Fas and FasL instead of integrin β4 in A549 human lung cancer cells

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 7, 2006, Pages 2438-2445

  Du, AiYing ^a,c   Zhao, BaoXiang ^a   Miao, JunYing ^a,c   Yin, DeLing ^b   Zhang, ShangLi ^a,c  

^a SHANDONG UNIVERSITY   (China)

^b East Tennessee State University   (United States)

^c BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

A549 cell apoptosis; Fas; FasL; Integrin 4; P53 protein; Safrole oxide

Indexed keywords

BETA4 INTEGRIN; CASPASE 3; CASPASE 8; CASPASE 9; FAS ANTIGEN; FAS LIGAND; SAFROLE; SAFROLE OXIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG ACTIVATION; DRUG MECHANISM; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LUNG CANCER; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; UPREGULATION; WESTERN BLOTTING;

ANTIGENS, CD95; APOPTOSIS; CELL LINE, TUMOR; FAS LIGAND PROTEIN; HUMANS; INTEGRIN BETA4; LUNG NEOPLASMS; MEMBRANE GLYCOPROTEINS; RECEPTORS, TUMOR NECROSIS FACTOR; SAFROLE; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTORS; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 32844462043     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.11.026     Document Type: Article

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