메뉴 건너뛰기




Volumn 19, Issue 1, 1998, Pages 141-146

In vivo genotoxicity and DNA adduct levels in the liver of rats treated with safrole

Author keywords

[No Author keywords available]

Indexed keywords

DNA; EPIDERMAL GROWTH FACTOR; NUCLEASE; SAFROLE;

EID: 0031845647     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/19.1.141     Document Type: Article
Times cited : (58)

References (37)
  • 3
    • 84961033628 scopus 로고
    • Toxic and possible carcinogenic effects of 4-allyl-1,2-methylenedioxybenzene (safrole) in rats on deficient diets
    • Homburger, F., Kelley, T. Jr, Friedler, G. and Russfield, A.B. (1961) Toxic and possible carcinogenic effects of 4-allyl-1,2-methylenedioxybenzene (safrole) in rats on deficient diets. Med. Exp., 4, 1-11.
    • (1961) Med. Exp. , vol.4 , pp. 1-11
    • Homburger, F.1    Kelley Jr., T.2    Friedler, G.3    Russfield, A.B.4
  • 5
    • 0015591485 scopus 로고
    • 1′-Hydroxysafrole, a proximate carcinogenic metabolite of safrole in the rat and mouse
    • Borchert, P., Miller, J.A., Miller, E.C. and Shires, T.K. (1973) 1′-Hydroxysafrole, a proximate carcinogenic metabolite of safrole in the rat and mouse. Cancer Res., 33, 590-600.
    • (1973) Cancer Res. , vol.33 , pp. 590-600
    • Borchert, P.1    Miller, J.A.2    Miller, E.C.3    Shires, T.K.4
  • 6
    • 0019788152 scopus 로고
    • Safrole: Its metabolism, carcinogenicity and interactions with cytochrome P-450
    • Ioannides, C., Delaforge, M. and Parke, D.V. (1981) Safrole: its metabolism, carcinogenicity and interactions with cytochrome P-450. Food Cosmet. Toxicol., 19, 657-666.
    • (1981) Food Cosmet. Toxicol. , vol.19 , pp. 657-666
    • Ioannides, C.1    Delaforge, M.2    Parke, D.V.3
  • 7
    • 0020595109 scopus 로고
    • The metabolic activation and nucleic acid adducts of naturally-occurring carcinogens: Recent results with ethyl carbamate and the spice flavors safrole and estragole
    • The 1983 Walter Hubert Lecture
    • Miller, J.A. and Miller, E.C. (1983) The metabolic activation and nucleic acid adducts of naturally-occurring carcinogens: recent results with ethyl carbamate and the spice flavors safrole and estragole. The 1983 Walter Hubert Lecture., Br. J. Cancer, 48, 1-15.
    • (1983) Br. J. Cancer , vol.48 , pp. 1-15
    • Miller, J.A.1    Miller, E.C.2
  • 8
    • 0021054404 scopus 로고
    • Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1′-sulfooxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1′-hydroxysafrole in mouse liver
    • Boberg, E.W., Miller, E.C., Miller, J.A., Poland, A. and Liem, A. (1983) Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1′-sulfooxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1′-hydroxysafrole in mouse liver. Cancer Res., 43, 5163-5173.
    • (1983) Cancer Res. , vol.43 , pp. 5163-5173
    • Boberg, E.W.1    Miller, E.C.2    Miller, J.A.3    Poland, A.4    Liem, A.5
  • 9
    • 0007658179 scopus 로고
    • Tests with the Salmonella plate-incorporation assay
    • Ashby, J. and De Serres, F.J. (eds) Elsevier, New York
    • Baker, R.S.U. and Bonin, A.M. (1985) Tests with the Salmonella plate-incorporation assay. In Ashby, J. and De Serres, F.J. (eds) Evaluation of Short-term Tests for Carcinogens. Elsevier, New York, pp. 177-180.
    • (1985) Evaluation of Short-term Tests for Carcinogens , pp. 177-180
    • Baker, R.S.U.1    Bonin, A.M.2
  • 10
    • 0000014818 scopus 로고
    • The in vitro chromosomal aberration test using Chinese hamster lung (CHL) fibroblast cells in culture
    • Ashby, J. and De Serres, F.J. (eds) Elsevier, New York
    • Ishidate, M. and Sofuni, T. (1985) The in vitro chromosomal aberration test using Chinese hamster lung (CHL) fibroblast cells in culture. In Ashby, J. and De Serres, F.J. (eds) Evaluation of Short-term Tests for Carcinogens. Elsevier, New York, pp. 427-432.
    • (1985) Evaluation of Short-term Tests for Carcinogens , pp. 427-432
    • Ishidate, M.1    Sofuni, T.2
  • 11
    • 0007687875 scopus 로고
    • The test for sister-chromatid exchanges in Chinese hamster V79 cells in culture
    • Ashby, J. and De Serres, F.J. (eds) Elsevier, New York
    • Van Went, G.F. (1985) The test for sister-chromatid exchanges in Chinese hamster V79 cells in culture. In Ashby, J. and De Serres, F.J. (eds) Evaluation of Short-term Tests for Carcinogens. Elsevier, New York, pp. 469-477.
    • (1985) Evaluation of Short-term Tests for Carcinogens , pp. 469-477
    • Van Went, G.F.1
  • 12
    • 0001600728 scopus 로고
    • Measurement of DNA single-strand breaks by alkaline elution in rat hepatocytes
    • Ashby, J. and De Serres, F.J. (eds) Elsevier, New York
    • Bradley, M.O. (1985) Measurement of DNA single-strand breaks by alkaline elution in rat hepatocytes. In Ashby, J. and De Serres, F.J. (eds) Evaluation of Short-term Tests for Carcinogens. Elsevier, New York, pp. 353-357.
    • (1985) Evaluation of Short-term Tests for Carcinogens , pp. 353-357
    • Bradley, M.O.1
  • 13
    • 0000776249 scopus 로고
    • Assays for the induction of gene mutations at the thymidine kinase locus in L5178Y mouse lymphoma cells in culture
    • Ashby, J. and De Serres, F.J. (eds) Elsevier, New York
    • Myhr, B., Bowers, L. and Caspary, W.J. (1985) Assays for the induction of gene mutations at the thymidine kinase locus in L5178Y mouse lymphoma cells in culture. In Ashby, J. and De Serres, F.J. (eds) Evaluation of Short-term Tests for Carcinogens. Elsevier, New York, pp. 555-568.
    • (1985) Evaluation of Short-term Tests for Carcinogens , pp. 555-568
    • Myhr, B.1    Bowers, L.2    Caspary, W.J.3
  • 14
    • 49049152044 scopus 로고
    • Mutagenicity of cosmetics ingredients licensed by the European communities
    • Gocke, E., King, M.T., Eckhardt, K. and Wild, D. (1981) Mutagenicity of cosmetics ingredients licensed by the European communities. Mutat. Res., 90, 91-109.
    • (1981) Mutat. Res. , vol.90 , pp. 91-109
    • Gocke, E.1    King, M.T.2    Eckhardt, K.3    Wild, D.4
  • 15
    • 0020397479 scopus 로고
    • Detection of genotoxic carcinogens in the in vivo - In vitro hepatocyte DNA repair assay
    • Mirsalis, J.C., Tyson, K. and Butterworth, B.E. (1982) Detection of genotoxic carcinogens in the in vivo - in vitro hepatocyte DNA repair assay. Environ. Mutagen., 4, 553-562.
    • (1982) Environ. Mutagen. , vol.4 , pp. 553-562
    • Mirsalis, J.C.1    Tyson, K.2    Butterworth, B.E.3
  • 17
    • 0018879891 scopus 로고
    • Do induced sperm-head abnormalities in mice specifically identify mammalian mutagens rather than carcinogens?
    • Topham, J.C. (1980) Do induced sperm-head abnormalities in mice specifically identify mammalian mutagens rather than carcinogens? Mutat. Res., 74, 379-387.
    • (1980) Mutat. Res. , vol.74 , pp. 379-387
    • Topham, J.C.1
  • 18
    • 0022273523 scopus 로고
    • Chemical and biochemical dosimetry of exposure to genotoxic chemicals
    • Wogan, G.N. and Gorelick, N.J. (1985) Chemical and biochemical dosimetry of exposure to genotoxic chemicals. Environ. Health Perspect., 62, 5-18.
    • (1985) Environ. Health Perspect. , vol.62 , pp. 5-18
    • Wogan, G.N.1    Gorelick, N.J.2
  • 19
    • 0023762467 scopus 로고
    • Chemical carcinogenesis: From animal models to molecular models in one decade
    • Yuspa, S.H. and Poirier, M.C. (1988) Chemical carcinogenesis: from animal models to molecular models in one decade. Adv. Cancer Res., 50, 25-70.
    • (1988) Adv. Cancer Res. , vol.50 , pp. 25-70
    • Yuspa, S.H.1    Poirier, M.C.2
  • 20
    • 0027382208 scopus 로고
    • DNA adducts, mutations and cancer
    • Hemminki, K. (1993) DNA adducts, mutations and cancer. Carcinogenesis, 14, 2007-2012.
    • (1993) Carcinogenesis , vol.14 , pp. 2007-2012
    • Hemminki, K.1
  • 21
    • 0025940602 scopus 로고
    • Chromosome aberrations, micronuclei and sister-chromatid exchanges (SCEs) in rat liver induced in vivo by hepatocarcinogens including heterocyclic amines
    • Sawada, S., Yamanaka, T., Yamatsu, K., Furihata, C. and Matsushima, T. (1991) Chromosome aberrations, micronuclei and sister-chromatid exchanges (SCEs) in rat liver induced in vivo by hepatocarcinogens including heterocyclic amines. Mutat. Res., 251, 59-69.
    • (1991) Mutat. Res. , vol.251 , pp. 59-69
    • Sawada, S.1    Yamanaka, T.2    Yamatsu, K.3    Furihata, C.4    Matsushima, T.5
  • 22
    • 0028348946 scopus 로고
    • Cumulative effects of chromosome aberrations and sister chromatid exchanges in rat liver induced in vivo by heterocyclic amines
    • Sawada, S., Daimon, H., Asakura, S., Kawaguchi, T., Yamatsu, K., Furihata, C. and Matsushima, T. (1994) Cumulative effects of chromosome aberrations and sister chromatid exchanges in rat liver induced in vivo by heterocyclic amines. Carcinogenesis, 15, 285-290.
    • (1994) Carcinogenesis , vol.15 , pp. 285-290
    • Sawada, S.1    Daimon, H.2    Asakura, S.3    Kawaguchi, T.4    Yamatsu, K.5    Furihata, C.6    Matsushima, T.7
  • 23
    • 0017101039 scopus 로고
    • Preparation of isolated rat liver cells
    • Seglen, P.O. (1976) Preparation of isolated rat liver cells. Meth. Cell Biol., 13, 29-83.
    • (1976) Meth. Cell Biol. , vol.13 , pp. 29-83
    • Seglen, P.O.1
  • 24
    • 0024382153 scopus 로고
    • In vivo short-term assays of repair and replication of rat liver DNA
    • Sawada, S., Furihata, C. and Matsushima, T. (1989) In vivo short-term assays of repair and replication of rat liver DNA. J. Cancer Res. Clin. Oncol., 115, 345-350.
    • (1989) J. Cancer Res. Clin. Oncol. , vol.115 , pp. 345-350
    • Sawada, S.1    Furihata, C.2    Matsushima, T.3
  • 25
    • 0022774562 scopus 로고
    • 32P-post-labeling test for structurally diverse DNA adducts
    • 32P-post-labeling test for structurally diverse DNA adducts. Carcinogenesis, 7, 1543-1551.
    • (1986) Carcinogenesis , vol.7 , pp. 1543-1551
    • Reddy, M.V.1    Randerath, K.2
  • 26
    • 0020334611 scopus 로고
    • 32P-post-labeling analysis of non-radioactive aromatic carcinogen - DNA adducts
    • 32P-post-labeling analysis of non-radioactive aromatic carcinogen - DNA adducts. Carcinogenesis, 3, 1081-1092.
    • (1982) Carcinogenesis , vol.3 , pp. 1081-1092
    • Gupta, R.C.1    Reddy, M.V.2    Randerath, K.3
  • 27
    • 0021646473 scopus 로고
    • 32P-Post-labeling analysis of DNA adducts formed in the livers of animals treated with safrole, estragole and other naturally-occurring alkenylbenzenes. I. Adult female CD-1 mice
    • 32P-Post-labeling analysis of DNA adducts formed in the livers of animals treated with safrole, estragole and other naturally-occurring alkenylbenzenes. I. Adult female CD-1 mice. Carcinogenesis, 5, 1613-1622.
    • (1984) Carcinogenesis , vol.5 , pp. 1613-1622
    • Randerath, K.1    Haglund, R.E.2    Phillips, D.H.3    Reddy, M.V.4
  • 29
    • 0023195911 scopus 로고
    • A comparative study of hepatic DNA repair, DNA replication and hepatotoxicity in the CD-1 mouse following multiple administrations of dimethylnitrosamine
    • Doolittle, D.J., Muller, G. and Scribner, H.E. (1987) A comparative study of hepatic DNA repair, DNA replication and hepatotoxicity in the CD-1 mouse following multiple administrations of dimethylnitrosamine. Mutat. Res., 188, 141-147.
    • (1987) Mutat. Res. , vol.188 , pp. 141-147
    • Doolittle, D.J.1    Muller, G.2    Scribner, H.E.3
  • 30
    • 0027406347 scopus 로고
    • Evaluation of the potential of riddelliine to induce unscheduled DNA synthesis, S-phase synthesis, or micronuclei following in vivo treatment with multiple doses
    • Mirsalis, J.C., Steinmetz, K.L., Blazak, W.F. and Spalding, J.W. (1993) Evaluation of the potential of riddelliine to induce unscheduled DNA synthesis, S-phase synthesis, or micronuclei following in vivo treatment with multiple doses. Environ. Mol. Mutagen., 21, 265-271.
    • (1993) Environ. Mol. Mutagen. , vol.21 , pp. 265-271
    • Mirsalis, J.C.1    Steinmetz, K.L.2    Blazak, W.F.3    Spalding, J.W.4
  • 31
    • 0027326903 scopus 로고
    • Formation and persistence of safrole - DNA adducts over a 10 000-fold dose range in mouse liver
    • Gupta, K.P., Van Golen, K.L., Putman, K.L. and Randerath, K. (1993) Formation and persistence of safrole - DNA adducts over a 10 000-fold dose range in mouse liver. Carcinogenesis, 14, 1517-1521.
    • (1993) Carcinogenesis , vol.14 , pp. 1517-1521
    • Gupta, K.P.1    Van Golen, K.L.2    Putman, K.L.3    Randerath, K.4
  • 32
    • 0021646474 scopus 로고
    • 32P-Post-labeling analysis of DNA adducts formed in the livers of animals treated with safrole, estragole and other naturally-occurring alkenylbenzenes. II. Newborn male B6C3F1 mice
    • 32P-Post-labeling analysis of DNA adducts formed in the livers of animals treated with safrole, estragole and other naturally-occurring alkenylbenzenes. II. Newborn male B6C3F1 mice. Carcinogenesis, 5, 1623-1628.
    • (1984) Carcinogenesis , vol.5 , pp. 1623-1628
    • Phillips, D.H.1    Reddy, M.V.2    Randerath, K.3
  • 33
    • 0022558710 scopus 로고
    • 32P-Post-labeling assay in mice of transplacental DNA damage induced by the environmental carcinogens safrole, 4-aminobiphenyl, and benzo[a]pyrene
    • 32P-Post-labeling assay in mice of transplacental DNA damage induced by the environmental carcinogens safrole, 4-aminobiphenyl, and benzo[a]pyrene. Cancer Res., 46, 3046-3054.
    • (1986) Cancer Res. , vol.46 , pp. 3046-3054
    • Lu, L.-J.W.1    Disher, R.M.2    Reddy, M.V.3    Randerath, K.4
  • 34
    • 0025078223 scopus 로고
    • Formation and persistence of novel benzo[a]pyrene adducts in rat lung, liver, and peripheral blood lymphocytes
    • Ross, J., Nelson, G., Kligerman, A., Erexson, G., Bryant, M., Earley, K., Gupta, R. and Nesnow, S. (1990) Formation and persistence of novel benzo[a]pyrene adducts in rat lung, liver, and peripheral blood lymphocytes. Cancer Res., 50, 5088-5094.
    • (1990) Cancer Res. , vol.50 , pp. 5088-5094
    • Ross, J.1    Nelson, G.2    Kligerman, A.3    Erexson, G.4    Bryant, M.5    Earley, K.6    Gupta, R.7    Nesnow, S.8
  • 35
    • 0023639585 scopus 로고
    • The correlation between DNA adducts and chromosomal aberrations in the target organ of benzidine exposed, partially-hepatectomized mice
    • Talaska, G., William, W.A., Ward, J.B., Randerath, K. and Legator, M.S. (1987) The correlation between DNA adducts and chromosomal aberrations in the target organ of benzidine exposed, partially-hepatectomized mice. Carcinogenesis, 8, 1899-1905.
    • (1987) Carcinogenesis , vol.8 , pp. 1899-1905
    • Talaska, G.1    William, W.A.2    Ward, J.B.3    Randerath, K.4    Legator, M.S.5
  • 36
    • 0024521983 scopus 로고
    • The role of specific DNA adducts in the induction of micronuclei by N-hydroxy-2-acetylaminofluorene in rat liver in vivo
    • Van de poll, M.L.M., Van der Hulst, D.A.M., Tates, A.D., Mulder, G.J. and Meerman, J.H.N. (1989) The role of specific DNA adducts in the induction of micronuclei by N-hydroxy-2-acetylaminofluorene in rat liver in vivo. Carcinogenesis, 10, 717-722.
    • (1989) Carcinogenesis , vol.10 , pp. 717-722
    • Van De Poll, M.L.M.1    Van Der Hulst, D.A.M.2    Tates, A.D.3    Mulder, G.J.4    Meerman, J.H.N.5
  • 37
    • 0030599151 scopus 로고    scopus 로고
    • In vivo mutagenicity and DNA adduct levels of heterocyclic amines in Muta™Mice and c-myc/lacZ double transgenic mice
    • Davis, C.D., Dacquel, E.J., Schut, H.A.J., Thorgeirsson, S.S. and Snyderwine, E.G. (1996) In vivo mutagenicity and DNA adduct levels of heterocyclic amines in Muta™Mice and c-myc/lacZ double transgenic mice. Mutat. Res., 356, 287-296.
    • (1996) Mutat. Res. , vol.356 , pp. 287-296
    • Davis, C.D.1    Dacquel, E.J.2    Schut, H.A.J.3    Thorgeirsson, S.S.4    Snyderwine, E.G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.