Safrole oxide induces apoptosis by activating caspase-3, -8, and -9 in A549 human lung cancer cells

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 1, 2006, Pages 81-83

  Du, AiYing ^a   Zhao, BaoXiang ^a   Yin, DeLing ^b   Zhang, ShangLi ^a   Miao, JunYing ^a  

^a SHANDONG UNIVERSITY   (China)

^b East Tennessee State University   (United States)

Author keywords

A549 cells; Apoptosis; Caspase promoter; Safrole oxide

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; ENZYME INDUCING AGENT; SAFROLE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DENSITY; CELL STRAIN; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CASPASE 6; CASPASE 8; CASPASE 9; CASPASES; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; COLORIMETRY; DRUG DESIGN; HUMANS; INFLAMMATION; LUNG NEOPLASMS; MODELS, CHEMICAL; SAFROLE; TIME FACTORS; UP-REGULATION;

EID: 27744519051     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.09.050     Document Type: Article

References (22)

1. C.B. Thompson Science 267 1995 1456
2. K. Subbaramaiah, T.P. Marmo, D.A. Dixon, and A.J. Dannenberg J. Biol. Chem. 278 2003 37637
3. S.L. Schreibe Science 287 2000 1954
4. J.R.J. Yeh, and C.M. Crews Dev. Cell 5 2003 11
5. C.M. Crews, and U. Splittgerber Trends Biochem. Sci. 24 1999 317
6. B.R. Stockwell Nat. Rev. Genet. 1 2000 116
7. B.X. Zhao, D.W. Wang, H. Zuo, G.T. Qian, and J.Y. Miao Chinese J. Org. Chem. 23 2003 1026
8. A.Y. Du, B.X. Zhao, S.L. Zhang, and J.Y. Miao Exp. Lung Res. 30 2004 419
9. A.Y. Du, B.X. Zhao, D.L. Yin, S.L. Zhang, and J.Y. Miao Bioorg. Med. Chem. 13 2005 4176
10. L. Goyal Cell 104 2001 805
11. A.G. Porter, and R.U. Janicke Cell Death Differ. 6 1999 99
12. H. Zou, Y. Li, X. Liu, and X. Wang J. Biol. Chem. 274 1999 11549
13. I.H. Engels, A. Stepczynska, C. Stroh, K. Lauber, C. Berg, R. Schwenzer, H. Wajant, R.U. Jänicke, A.G. Porter, C. Belka, M. Gregor, K. Schulze-Osthoff, and S. Wesselborg Oncogene 19 2000 4563
14. F. Pirnia, E. Schneider, D.C. Betticher, and M.M. Borner Cell Death Differ. 9 2002 905
15. X.D. Wang Genes Dev. 15 2001 2922
16. S. Hunot, and R.A. Flavell Science 292 2001 865
17. K.B. Kim, Y.H. Choi, I.K. Kim, C.W. Chung, B.J. Kim, Y.M. Park, and Y.K. Jung Cytokine 20 2002 283
18. P. Shankaranarayanan, and S. Nigam J. Immunol. 170 2003 887
19. G.C. Chang, S.L. Hsu, J.R. Tsai, F.P. Liang, S.Y. Lin, G.T. Sheu, and C.Y. Chen Biochem. Pharmacol. 68 2004 1453
20. J.S. Chang, Y.L. Hsu, P.L. Kuo, L.C. Chiang, and C.C. Lin Clin. Exp. Pharmacol. Physiol. 31 2004 716
21. Debatin, K. M. In Caspases: Their Role in Cell Death and Cell Survival; Marek, L., Walczak, H., Eds.; Kluwer: New York, 2002; Chapter 12.
22. X. Xie, X. Zhao, Y. Liu, J. Zhang, R.J. Matusik, K.M. Slawin, and D.M. Spencer Cancer Res. 61 2001 6795