-
1
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg R., The hallmarks of cancer. Cell 2000; 100: 57-70. (Pubitemid 30046295)
-
(2000)
Cell
, vol.100
, Issue.1
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
0002145419
-
New technologies in the epidermal growth factor receptor-targeted cancer therapy
-
Baselga J., New technologies in the epidermal growth factor receptor-targeted cancer therapy. Signal 2000; 1: 12-21.
-
(2000)
Signal
, vol.1
, pp. 12-21
-
-
Baselga, J.1
-
3
-
-
0041629450
-
Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer
-
DOI 10.1200/JCO.2003.01.504
-
Mendelsohn J, Baselga J., Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer. J Clin Oncol 2003; 21: 2787-99. (Pubitemid 46606324)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.14
, pp. 2787-2799
-
-
Mendelsohn, J.1
Baselga, J.2
-
4
-
-
0021273420
-
Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
-
Ullrich A, Coussens L, Hayflick JS, Dull TJ, et al,. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature 1984; 309: 418-25. (Pubitemid 14102443)
-
(1984)
Nature
, vol.309
, Issue.5967
, pp. 418-425
-
-
Ullrich, A.1
Coussens, L.2
Hayflick, J.S.3
-
5
-
-
18644386251
-
Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains
-
DOI 10.1016/S0092-8674(02)00963-7
-
Ogiso H, Ishitani R, Nureki O, Fukai S, et al,. Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains. Cell 2002; 110: 775-87. (Pubitemid 35291060)
-
(2002)
Cell
, vol.110
, Issue.6
, pp. 775-787
-
-
Ogiso, H.1
Ishitani, R.2
Nureki, O.3
Fukai, S.4
Yamanaka, M.5
Kim, J.-H.6
Saito, K.7
Sakamoto, A.8
Inoue, M.9
Shirouzu, M.10
Yokoyama, S.11
-
7
-
-
0036632368
-
The phosphatidylinositol 3-kinase-AKT pathway in human cancer
-
Vivanco I, Sawyers CL., The phosphatidylinositol 3-kinase-Akt pathway in human cancer. Nat Rev Cancer 2002; 2: 489-501. (Pubitemid 37328931)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.7
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
8
-
-
0030795612
-
The ErbB signaling network in embryogenesis and oncogenesis: Signal diversification through combinatorial ligand-receptor interactions
-
DOI 10.1016/S0014-5793(97)00412-2, PII S0014579397004122
-
Alroy I, Yarden Y., The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand-receptor interactions. FEBS Lett 1997; 410: 83-6. (Pubitemid 27283389)
-
(1997)
FEBS Letters
, vol.410
, Issue.1
, pp. 83-86
-
-
Alroy, I.1
Yarden, Y.2
-
9
-
-
0029160069
-
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
-
Burgering BM, Coffer PJ., Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 1995; 376: 599-602.
-
(1995)
Nature
, vol.376
, pp. 599-602
-
-
Burgering, B.M.1
Coffer, P.J.2
-
10
-
-
0021135608
-
Comparison of epidermal growth factor binding and receptor distribution in normal human epidermis and epidermal appendages
-
Nanney LB, Magid M, Stoscheck CM, King LE Jr., Comparison of epidermal growth factor binding and receptor distribution in normal human epidermis and epidermal appendages. J Invest Dermatol 1984; 83: 385-93. (Pubitemid 14024387)
-
(1984)
Journal of Investigative Dermatology
, vol.83
, Issue.5
, pp. 385-393
-
-
Nanney, L.B.1
Magid, M.2
Stoscheck, C.M.3
King Jr., L.E.4
-
11
-
-
0025868272
-
Immunohistochemical detection of the epidermal growth factor receptor in paraffin-embedded human tissues
-
Gullick WJ, Hughes CM, Mellon K, Neal DE, et al,. Immunohistochemical detection of the epidermal growth factor receptor in paraffin-embedded human tissues. J Pathol 1991; 164: 285-9.
-
(1991)
J Pathol
, vol.164
, pp. 285-289
-
-
Gullick, W.J.1
Hughes, C.M.2
Mellon, K.3
Neal, D.E.4
-
12
-
-
0036500831
-
Monoclonal antibodies to target epidermal growth factor receptor-positive tumors a new paradigm for cancer therapy
-
DOI 10.1002/cncr.10372
-
Herbst RS, Shin DM., Monoclonal antibodies to target epidermal growth factor receptor-positive tumors. A new paradigm for cancer therapy. Am Cancer Soc 2002; 94: 1593-611. (Pubitemid 34212655)
-
(2002)
Cancer
, vol.94
, Issue.5
, pp. 1593-1611
-
-
Herbst, R.S.1
Shin, D.M.2
-
13
-
-
0034777482
-
Epidermal growth factor receptor and HER2-neu mRNA expression in non-small cell lung cancer is correlated with survival
-
Brabender J, Danenberg KD, Metzger R, Schneider PM, et al,. Epidermal growth factor receptor and HER2-neu mRNA expression in non-small cell lung cancer is correlated with survival. Clin Cancer Res 2001; 7: 1850-5. (Pubitemid 32994816)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.7
, pp. 1850-1855
-
-
Brabender, J.1
Danenberg, K.D.2
Metzger, R.3
Schneider, P.M.4
Park, J.5
Salonga, D.6
Holscher, A.H.7
Danenberg, P.V.8
-
14
-
-
0021888127
-
Epidermal growth factor receptors in different skin tumors
-
Bauknecht T, Gross G, Hagedorn M., Epidermal growth factor receptors in different skin tumors. Dermatologica 1985; 171: 16-20. (Pubitemid 15069675)
-
(1985)
Dermatologica
, vol.171
, Issue.1
, pp. 16-20
-
-
Bauknecht, T.1
Gross, G.2
Hagedorn, M.3
-
15
-
-
0030154587
-
The expression of c- erbB-1 and c-erbB-2 oncogenes in basal cell carcinoma and squamous cell carcinoma of skin
-
Liu B, Zhang H, Li S, Chen W, et al,. The expression of c- erbB-1 and c-erbB-2 oncogenes in basal cell carcinoma and squamous cell carcinoma of skin. Chin Med Sci J 1996; 11: 106-9.
-
(1996)
Chin Med Sci J
, vol.11
, pp. 106-109
-
-
Liu, B.1
Zhang, H.2
Li, S.3
Chen, W.4
-
16
-
-
0026558998
-
Abnormal expression of epidermal growth factor receptor in cutaneous epithelial tumors
-
Groves RW, Allen MH, MacDonald DM., Abnormal expression of epidermal growth factor receptor in cutaneous epithelial tumors. J Cutan Pathol 1992; 19: 66-72.
-
(1992)
J Cutan Pathol
, vol.19
, pp. 66-72
-
-
Groves, R.W.1
Allen, M.H.2
MacDonald, D.M.3
-
17
-
-
0035135632
-
Coexpression patterns of EGFR, HER2, HER3 and HER4 in non-melanoma skin cancer
-
DOI 10.1016/S0959-8049(00)00364-6, PII S0959804900003646
-
Krahn G, Leiter U, Kaskel P, Udart M, et al,. Coexpression patterns of EGFR, HER2, HER3 and HER4 in non-melanoma skin cancer. Eur J Cancer 2001; 37: 251-9. (Pubitemid 32144704)
-
(2001)
European Journal of Cancer
, vol.37
, Issue.2
, pp. 251-259
-
-
Krahn, G.1
Leiter, U.2
Kaskel, P.3
Udart, M.4
Utikal, J.5
Bezold, G.6
Peter, R.U.7
-
18
-
-
0034980383
-
Epidermal growth factor receptor overexpression and genetic aberrations in metastatic squamous-cell carcinoma of the skin
-
DOI 10.1159/000051637
-
Shimizu T, Izumi H, Oga A, Furumoto H, et al,. Epidermal growth factor receptor overexpression and genetic aberrations in metastatic squamous cell carcinoma of the skin. Dermatology 2001; 202: 203-6. (Pubitemid 32506966)
-
(2001)
Dermatology
, vol.202
, Issue.3
, pp. 203-206
-
-
Shimizu, T.1
Izumi, H.2
Oga, A.3
Furumoto, H.4
Murakami, T.5
Ofuji, R.6
Muto, M.7
Sasaki, K.8
-
19
-
-
40849147041
-
EGFR antagonist in cancer treatment
-
Ciardiello F, Tortora G., EGFR antagonist in cancer treatment. N Engl J Med 2008; 358: 1160-74.
-
(2008)
N Engl J Med
, vol.358
, pp. 1160-1174
-
-
Ciardiello, F.1
Tortora, G.2
-
20
-
-
1642421130
-
Target-based agents against ErbB receptors and their ligands: A novel approach to cancer treatment
-
DOI 10.1677/erc.0.0100001
-
Normanno N, Bianco C, De Luca A, Maiello MR, et al,. Target-based agents against ErbB receptors and their ligands: a novel approach to cancer treatment. Endocr Relat Cancer 2003; 10: 1-21. (Pubitemid 36457237)
-
(2003)
Endocrine-Related Cancer
, vol.10
, Issue.1
, pp. 1-21
-
-
Normanno, N.1
Bianco, C.2
De Luca, A.3
Maiello, M.R.4
Salomon, D.S.5
-
21
-
-
36749002116
-
Rational combination of targeted therapies as a strategy to overcome the mechanisms of resistance to inhibitors of EGFR signaling
-
DOI 10.2174/138161207782360537
-
Bianco R, Damiano V, Gelardi T, Daniele G, et al,. Rational combination of targeted therapies as a strategy to overcome the mechanisms of resistance to inhibitors of EGFR signaling. Curr Pharm Des 2007; 13: 3358-67. (Pubitemid 350201670)
-
(2007)
Current Pharmaceutical Design
, vol.13
, Issue.33
, pp. 3358-3367
-
-
Bianco, R.1
Damiano, V.2
Gelardi, T.3
Daniele, G.4
Ciardiello, F.5
Tortora, G.6
-
22
-
-
14844318077
-
When kinases meet mathematics: The systems biology of MAPK signalling
-
DOI 10.1016/j.febslet.2005.02.002, Systems Biology
-
Kolch W, Calder M, Gilbert D., When kinases meet mathematics: the systems biology of MAPK signaling. FEBS Lett 2005; 579: 1891-5. (Pubitemid 40342670)
-
(2005)
FEBS Letters
, vol.579
, Issue.8
, pp. 1891-1895
-
-
Kolch, W.1
Calder, M.2
Gilbert, D.3
-
23
-
-
0037499945
-
Response to epidermal growth factor receptor inhibitors in non-small cell lung cancer cells: Limited antiproliferative effects and absence of apoptosis associated with persistent activity of extracellular signal-regulated kinase or Akt kinase pathways
-
Janmaat ML, Kruyt FA, Rodriguez JA, Giaccone G., Response to epidermal growth factor receptor inhibitors in non-small cell lung cancer cells: limited antiproliferative effects and absence of apoptosis associated with persistent activity of extracellular signal regulated kinase or Akt kinase pathways. Clin Cancer Res 2003; 9: 2316-26. (Pubitemid 36687658)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.6
, pp. 2316-2326
-
-
Janmaat, M.L.1
Kruyt, F.A.E.2
Rodriguez, J.A.3
Giaccone, G.4
-
24
-
-
0031039923
-
Transforming growth factor-α-induced transcriptional activation of the Vascular permeability factor (VPF/VEGF) gene requires AP-2-dependent DNA binding and transactivation
-
DOI 10.1093/emboj/16.4.750
-
Gille J, Swerlick RA, Caughman SW., Transforming growth factor alpha- induced transcriptional activation of the vascular permeability factor (VPF/VEGF) gene requires AP-2- dependent DNA binding and transactivation. EMBO J 1997; 16: 750-9. (Pubitemid 27089522)
-
(1997)
EMBO Journal
, vol.16
, Issue.4
, pp. 750-759
-
-
Gille, J.1
Swerlick, R.A.2
Caughman, S.W.3
-
25
-
-
0035953399
-
In vitro and in vivo inhibition of epidermal growth factor receptor-tyrosine kinase pathway by photodynamic therapy
-
DOI 10.1038/sj.onc.1204313
-
Ahmed N, Kalka K, Mukhtar H., In vitro and in vivo inhibition of epidermal growth factor receptor-tyrosine kinase pathway by photodynamic therapy. Oncogene 2001; 20: 2314-7. (Pubitemid 32531289)
-
(2001)
Oncogene
, vol.20
, Issue.18
, pp. 2314-2317
-
-
Ahmad, N.1
Kalka, K.2
Mukhtar, H.3
-
26
-
-
0037805547
-
RAS oncogenes: The first 30 years
-
DOI 10.1038/nrc1097
-
Malumbres M, Barbacid M., RAS oncogenes: the first 30 years. Nat Rev Cancer 2003; 3: 459-65. (Pubitemid 37328850)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.6
, pp. 459-465
-
-
Malumbres, M.1
Barbacid, M.2
-
27
-
-
34047248571
-
Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies
-
DOI 10.1158/0008-5472.CAN-06-4158
-
Benvenuti S, Sartore-Bianchi A, Di Nicolantonio F, Zanon C, et al,. Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies. Cancer Res 2007; 67: 2643-8. (Pubitemid 46548951)
-
(2007)
Cancer Research
, vol.67
, Issue.6
, pp. 2643-2648
-
-
Benvenuti, S.1
Sartore-Bianchi, A.2
Di Nicolantonio, F.3
Zanon, C.4
Moroni, M.5
Veronese, S.6
Siena, S.7
Bardelli, A.8
-
28
-
-
57449095367
-
Wild-type BRAF is required to panitumumab or cetuximab in metastatic colorectal cancer
-
Di Nicolantonio F, Martini M, Molinari F, Sartore-Bianchi A, et al,. Wild-type BRAF is required to panitumumab or cetuximab in metastatic colorectal cancer. J Clin Oncol 2008; 26: 5705-12.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5705-5712
-
-
Di Nicolantonio, F.1
Martini, M.2
Molinari, F.3
Sartore-Bianchi, A.4
-
29
-
-
0032520009
-
4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway
-
Gingras AC, Kennedy SG, O'Leary MA, Sonenberg N, et al,. 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt (PKB) signaling pathway. Genes Dev 1998; 12: 502-13. (Pubitemid 28101013)
-
(1998)
Genes and Development
, vol.12
, Issue.4
, pp. 502-513
-
-
Gingras, A.-C.1
Kennedy, S.G.2
O'Leary, M.A.3
Sonenberg, N.4
Hay, N.5
-
30
-
-
0032972944
-
Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice
-
Perrotte P, Matsumoto T, Inoue K, Kuniyasu H, et al,. Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice. Clin Cancer Res 1999; 5: 257-65. (Pubitemid 29085177)
-
(1999)
Clinical Cancer Research
, vol.5
, Issue.2
, pp. 257-265
-
-
Perrotte, P.1
Matsumoto, T.2
Inoue, K.3
Kuniyasu, H.4
Eve, B.Y.5
Hicklin, D.J.6
Radinsky, R.7
Dinney, C.P.N.8
-
31
-
-
33144484457
-
Multicenter phase I/II study of cetuximab with paclitaxel and carboplatin in untreated patients with stage IV non-small-cell lung cancer
-
DOI 10.1200/JCO.2005.03.1997
-
Thienelt CD, Bunn PA Jr, Hanna N, Rosenberg A, et al,. A multi-centered phase I/II study of cetuximab in combination with paclitaxel and carboplatin in untreated patients with stage IV non-small cell lung cancer. J Clin Oncol 2005; 23: 8786-93. (Pubitemid 46211524)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.34
, pp. 8786-8793
-
-
Thienelt, C.D.1
Bunn Jr., P.A.2
Hanna, N.3
Rosenberg, A.4
Needle, M.N.5
Long, M.E.6
Gustafson, D.L.7
Kelly, K.8
-
32
-
-
1942419617
-
A phase i study of cetuximab in combination with cisplatin or carboplatin and 5-FU in patients with recurrent or metastatic squamous cell carcinoma of the head and neck
-
Vega-Villegas E, Awada R, Mesia L, Geoffrois L, et al,. A phase I study of cetuximab in combination with cisplatin or carboplatin and 5-FU in patients with recurrent or metastatic squamous cell carcinoma of the head and neck. Proc Am Assoc Cancer Res 2003; 22: 2020.
-
(2003)
Proc Am Assoc Cancer Res
, vol.22
, pp. 2020
-
-
Vega-Villegas, E.1
Awada, R.2
Mesia, L.3
Geoffrois, L.4
-
33
-
-
24944490558
-
Phase II multicenter study of the epidermal growth factor receptor antibody cetuximab and cisplatin for recurrent and refractory squamous cell carcinoma of the head and neck
-
Herbst RS, Arquette M, Shin DM, Dicke K, et al,. Phase II multicenter study of the epidermal growth factor receptor antibody cetuximab and cisplatin for recurrent and refractory squamous cell carcinoma of the head and neck. J Clin Oncol 23: 5578-87.
-
J Clin Oncol
, vol.23
, pp. 5578-5587
-
-
Herbst, R.S.1
Arquette, M.2
Shin, D.M.3
Dicke, K.4
-
34
-
-
34250879547
-
Cutaneous squamous cell carcinoma responding serially to single-agent cetuximab
-
DOI 10.1097/CAD.0b013e32809ef9e0, PII 0000181320070800000011
-
Suen JK, Bressler L, Shord SS, Warso M, et al,. Cutaneous squamous cell carcinoma responding serially to single-agent cetuximab. Anti-Cancer Drugs 2007; 18: 827-9. (Pubitemid 46975970)
-
(2007)
Anti-Cancer Drugs
, vol.18
, Issue.7
, pp. 827-829
-
-
Suen, J.K.1
Bressler, L.2
Shord, S.S.3
Warso, M.4
Villano, J.L.5
-
35
-
-
76249099489
-
Cetuximab induced hypertrichosis of the scalp and eyelashes
-
Van-Galvan S, Buceta RL, Ma D-L, Fernandez-Chacon C, et al,. Cetuximab induced hypertrichosis of the scalp and eyelashes. J Am Acad Dermatol 2010; 62: 531-2.
-
(2010)
J Am Acad Dermatol
, vol.62
, pp. 531-532
-
-
Van-Galvan, S.1
Buceta, R.L.2
Ma, D.-L.3
Fernandez-Chacon, C.4
-
36
-
-
67651122929
-
Cetuximab therapy of metastasizing cutaneous squamous cell carcinoma in a patient with severe recessive dystrophic epidermolysis bullosa
-
Arnold AW, Bruckner-Tuderman L, Zuger C, Itin HP., Cetuximab therapy of metastasizing cutaneous squamous cell carcinoma in a patient with severe recessive dystrophic epidermolysis bullosa. Dermatology 2009; 219: 80-3.
-
(2009)
Dermatology
, vol.219
, pp. 80-83
-
-
Arnold, A.W.1
Bruckner-Tuderman, L.2
Zuger, C.3
Itin, H.P.4
-
37
-
-
57649108802
-
Combination of an EGFR blocker and a COX-2 inhibitor for the treatment of advanced cutaneous squamous cell carcinoma
-
Jalili A, Pinc A, Pieczkowski F, Karlhofer FM, et al,. Combination of an EGFR blocker and a COX-2 inhibitor for the treatment of advanced cutaneous squamous cell carcinoma. J Deut Dermatol Gesellschaft 2008; 6: 1066-9.
-
(2008)
J Deut Dermatol Gesellschaft
, vol.6
, pp. 1066-1069
-
-
Jalili, A.1
Pinc, A.2
Pieczkowski, F.3
Karlhofer, F.M.4
-
38
-
-
34447121976
-
EGFR activation results in enhanced cyclooxygenase-2 expression through p38 mitogen-activated protein kinase-dependent activation of the Sp1/Sp3 transcription factors in human gliomas
-
DOI 10.1158/0008-5472.CAN-07-0141
-
Xu K, Shu HK., EGFR activation results in enhanced cyclooxygenase-2 expression through p38 mitogen-activated protein kinase-dependent activation of the Sp1-Sp3 transcription factors in human gliomas. Cancer Res 2007; 67: 6121-9. (Pubitemid 47037492)
-
(2007)
Cancer Research
, vol.67
, Issue.13
, pp. 6121-6129
-
-
Xu, K.1
Shu, H.-K.G.2
-
39
-
-
0035117355
-
Development of ABX-EGF, a fully human anti-EGF receptor monoclonal antibody, for cancer therapy
-
DOI 10.1016/S1040-8428(00)00134-7, PII S1040842800001347
-
Yang XD, Jia XC, Corvalan JRF, Wang P, et al,. Development of ABX-EGF, a fully human anti-EGF receptor monoclonal antibody, for cancer therapy. Crit Rev Oncol Hematol 2001; 38: 17-23. (Pubitemid 32194591)
-
(2001)
Critical Reviews in Oncology/Hematology
, vol.38
, Issue.1
, pp. 17-23
-
-
Yang, X.-D.1
Jia, X.-C.2
Corvalan, J.R.F.3
Wang, P.4
Davis, C.G.5
-
40
-
-
38949178132
-
Dose and schedule study of panitumumab monotherapy in patients with advanced solid malignancies
-
DOI 10.1158/1078-0432.CCR-07-1509
-
Weiner LM, Belldegrum AS, Crawford J, Tolcher AW, et al,. Dose and schedule study of panitumumab monotherapy in patients with advanced solid malignancies. Clin Cancer Res 2008; 14: 502-8. (Pubitemid 351226119)
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.2
, pp. 502-508
-
-
Weiner, L.M.1
Belldegrun, A.S.2
Crawford, J.3
Tolcher, A.W.4
Lockbaum, P.5
Arends, R.H.6
Navale, L.7
Amado, R.G.8
Schwab, G.9
Figlin, R.A.10
-
41
-
-
1542344622
-
Phase I study of the humanized antiepidermal growth factor receptor monoclonal antibody EMD72000 in patients with advanced solid tumors that express the epidermal growth factor receptor
-
DOI 10.1200/JCO.2004.05.114
-
vanhoefer U, Tewes M, Rojo F, Dirsch O, et al,. Phase I study of the humanized antiepidermal growth factor receptor monoclonal antibody in patients with advanced solid tumors that express the EGFR. J Clin Oncol 2004; 22: 175-84. (Pubitemid 41095130)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.1
, pp. 175-184
-
-
Vanhoefer, U.1
Tewes, M.2
Rojo, F.3
Dirsch, O.4
Schleucher, N.5
Rosen, O.6
Tillner, J.7
Kovar, A.8
Braun, A.H.9
Trarbach, T.10
Seeber, S.11
Harstrick, A.12
Baselga, J.13
-
42
-
-
33846950834
-
A phase II trial of EMD 72000 (matuzumab), a humanized anti-EGFR monoclonal antibody in patients with platinum-resistance ovarian and primary peritoneal malignancies
-
Seiden MV, Burris HA, Matulonis U, Hall JB, et al,. A phase II trial of EMD 72000 (matuzumab), a humanized anti-EGFR monoclonal antibody in patients with platinum-resistance ovarian and primary peritoneal malignancies. Gynecol Oncol 2007; 104: 727-31.
-
(2007)
Gynecol Oncol
, vol.104
, pp. 727-731
-
-
Seiden, M.V.1
Burris, H.A.2
Matulonis, U.3
Hall, J.B.4
-
43
-
-
0034068319
-
Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor- selective tyrosine kinase inhibitor
-
Ciardiello F, Caputo R, Bianco R, Damiano V, et al,. Antitumor effect of potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa) an epidermal growth factor receptor selective tyrosine kinase inhibitor. Clini Cancer Res 2000; 6: 2053-63. (Pubitemid 30305105)
-
(2000)
Clinical Cancer Research
, vol.6
, Issue.5
, pp. 2053-2063
-
-
Ciardiello, F.1
Caputo, R.2
Bianco, R.3
Damiano, V.4
Pomatico, G.5
De Placido, S.6
Bianco, A.R.7
Tortora, G.8
-
44
-
-
0345300537
-
Suppression of epidermal growth factor receptor mitogen activated protein kinase and Pak 1 pathways and invasiveness of human cutaneous squamous cancer cells by the tyrosine kinase inhibitor ZD1839 (Iressa)
-
Barnes CJ, Bagheri-Yarmand R, Mandal M, Yang Z, et al,. Suppression of epidermal growth factor receptor mitogen activated protein kinase and Pak 1 pathways and invasiveness of human cutaneous squamous cancer cells by the tyrosine kinase inhibitor ZD1839 (Iressa). Mol Cancer Ther 2003; 2: 345-51.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 345-351
-
-
Barnes, C.J.1
Bagheri-Yarmand, R.2
Mandal, M.3
Yang, Z.4
-
45
-
-
2342471392
-
Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non-Small-Cell Lung Cancer to Gefitinib
-
DOI 10.1056/NEJMoa040938
-
Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, et al,. Activating mutations in the epidermal growth receptor underlying responsiveness of non-small lung cancer to gefitinib. N Engl J Med 2004; 350: 2129-39. (Pubitemid 38637993)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
Harris, P.L.7
Haserlat, S.M.8
Supko, J.G.9
Haluska, F.G.10
Louis, D.N.11
Christiani, D.C.12
Settleman, J.13
Haber, D.A.14
-
46
-
-
0030774045
-
Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase
-
Moyer JD, Barbacci EG, Iwata KK, Arnold L, et al,. Induction of apoptosis and cell cycle arrest by and epidermal growth receptor inhibitor tyrosine kinase. Cancer Res 1997; 57: 4838-48. (Pubitemid 27468992)
-
(1997)
Cancer Research
, vol.57
, Issue.21
, pp. 4838-4848
-
-
Moyer, J.D.1
Barbacci, E.G.2
Iwata, K.K.3
Arnold, L.4
Boman, B.5
Cunningham, A.6
DiOrio, C.7
Doty, J.8
Morin, M.J.9
Moyer, M.P.10
Neveu, M.11
Pollack, V.A.12
Pustilnik, L.R.13
Reynolds, M.M.14
Sloan, D.15
Theleman, A.16
Miller, P.17
-
47
-
-
0037667417
-
Preclinical studies with erlotinib (Tarceva)
-
Akita RW, Sliwkowski MX., Preclinical studies with Erlotinib (Tarceva). Semin Oncol 2003; 30: 15-24. (Pubitemid 36828624)
-
(2003)
Seminars in Oncology
, vol.30
, Issue.3 SUPPL. 7
, pp. 15-24
-
-
Akita, R.W.1
Sliwkowski, M.X.2
-
48
-
-
0038343121
-
Erlotinib (Tarceva): An update on the clinical trial program
-
Herbst RS., Erlotinib (Tarceva): an update on the clinical trial program. Semin Oncol 2003; 30 (Suppl 7): 34-46. (Pubitemid 36828626)
-
(2003)
Seminars in Oncology
, vol.30
, Issue.3 SUPPL. 7
, pp. 34-46
-
-
Herbst, R.S.1
-
49
-
-
1242273590
-
ErbB2) is regulated by heregulin through heterodimer formation with ErbB3 yet remains sensitive to the dual EGFR/ErbB2 kinase inhibitor GW572016
-
DOI 10.1038/sj.onc.1207166
-
Xia W, Liu LH, Ho P, Spector NL., Truncated ErbB2 receptor is regulated by heregulin through heterodimer formation with ErbB3 yet remains sensitive to the dual EGFR/ErBb2 kinase inhibitor GW572016. Oncogene 2004; 23: 646-53. (Pubitemid 38241266)
-
(2004)
Oncogene
, vol.23
, Issue.3
, pp. 646-653
-
-
Xia, W.1
Liu, L.-H.2
Ho, P.3
Spector, N.L.4
-
50
-
-
3042782959
-
Epidermal growth factor receptor tyrosine kinase inhibitors
-
Ranson M., Epidermal growth factor receptor tyrosine kinase inhibitors. Br J Cancer 2004; 90: 2250-5. (Pubitemid 38961885)
-
(2004)
British Journal of Cancer
, vol.90
, Issue.12
, pp. 2250-2255
-
-
Ranson, M.1
-
51
-
-
1842791537
-
Pharmcokinetics and pharmacodynamic properties of EGFR inhibitors under clinical investigation
-
Thomas SM, Grandis JR., Pharmcokinetics and pharmacodynamic properties of EGFR inhibitors under clinical investigation. Cancer Treat Rev 2004; 30: 225-68.
-
(2004)
Cancer Treat Rev
, vol.30
, pp. 225-268
-
-
Thomas, S.M.1
Grandis, J.R.2
-
52
-
-
0035724536
-
Cutaneous side-effects in cancer patients treated with the antiepidermal growth factor receptor antibody C225
-
DOI 10.1046/j.1365-2133.2001.04226.x
-
Busam KJ, Capodieci P, Motzer R, Kiehn T, et al,. Cutaneous side-effects in cancer patients treated with the antiepidermal growth factor receptor antibody C225. Br J Dermatol 2001; 144: 1169-76. (Pubitemid 34204207)
-
(2001)
British Journal of Dermatology
, vol.144
, Issue.6
, pp. 1169-1176
-
-
Busam, K.J.1
Capodieci, P.2
Motzer, R.3
Kiehn, T.4
Phelan, D.5
Halpern, A.C.6
-
53
-
-
33746920516
-
Description and management of cutaneous side effects during cetuximab or erlotinib treatments: A prospective study of 30 patients
-
DOI 10.1016/j.jaad.2006.04.062, PII S0190962206012424
-
Roe E, Muret GM, Marcuello E, Capdevila J, et al,. Description and management of cutaneous side effects during cetuximab or erlotinib treatments: a prospective study of 30 patients. J Am Acad Dermatol 2006; 55: 429-37. (Pubitemid 44189595)
-
(2006)
Journal of the American Academy of Dermatology
, vol.55
, Issue.3
, pp. 429-437
-
-
Roe, E.1
Garcia Muret, M.P.2
Marcuello, E.3
Capdevila, J.4
Pallares, C.5
Alomar, A.6
-
54
-
-
21344462378
-
Cutaneous side-effects of kinase inhibitors and blocking antibodies
-
DOI 10.1016/S1470-2045(05)70243-6, PII S1470204505702436
-
Robert C, Sorai JC, Spatz A, Le Cesne A, et al,. Cutaneous side effects of kinase inhibitors and blocking antibodies. Lancet Oncol 2005; 6: 491-500. (Pubitemid 40903630)
-
(2005)
Lancet Oncology
, vol.6
, Issue.7
, pp. 491-500
-
-
Robert, C.1
Soria, J.-C.2
Spatz, A.3
Le Cesne, A.4
Malka, D.5
Pautier, P.6
Wechsler, J.7
Lhomme, C.8
Escudier, B.9
Boige, V.10
Armand, J.-P.11
Le Chevalier, T.12
|