Cetuximab-induced hypertrichosis of the scalp and eyelashes

Journal of the American Academy of Dermatology

Volumn 62, Issue 3, 2010, Pages 531-533

  Vano Galvan, Sergio ^a   Ríos Buceta, Luis ^a   Ma, Dong Lai ^b   Fernández Chacón, Concepción ^c   Viera, Juan Carlos ^c   Jaén, Pedro ^a  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

^b PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^c MD International Center   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CETUXIMAB;

ARTICLE; BRAIN METASTASIS; CANCER RADIOTHERAPY; CANCER RELAPSE; CANCER SURGERY; CHEMOSURGERY; EYELASH; HAIR ANALYSIS; HUMAN; HYPERTRICHOSIS; MALE TYPE ALOPECIA; OCCIPITAL LOBE; PALLIATIVE THERAPY; PARIETAL LOBE; PHYSICAL EXAMINATION; PRIORITY JOURNAL; SCALP; SKIN BIOPSY; SKIN METASTASIS; SQUAMOUS CELL CARCINOMA;

AGED, 80 AND OVER; ANTIBODIES, MONOCLONAL; CARCINOMA, SQUAMOUS CELL; EYELASHES; HEAD AND NECK NEOPLASMS; HUMANS; HYPERTRICHOSIS; MALE; RECEPTOR, EPIDERMAL GROWTH FACTOR; SCALP; SKIN NEOPLASMS;

EID: 76249099489     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaad.2009.02.023     Document Type: Article

References (8)

1. Bonner J.A., Harari P.M., Giralt J., Azarnia N., Shin D.M., Cohen R.B., et al. Radiotherapy plus cetuximab for squamous cell carcinoma of the head and neck. N Engl J Med 354 (2006) 567-578
2. Suen J.K., Bressler L., Shord S.S., Warso M., and Villano J.L. Cutaneous squamous cell carcinoma responding serially to single-agent cetuximab. Anticancer Drugs 18 (2007) 827-829
3. Vano-Galvan S., de las Heras E., Harto A., and Jaen P. Severe cutaneous toxicity during concomitant radiotherapy and cetuximab treatment of head and neck cancer. Eur J Dermatol 18 (2008) 471-472
4. Agero A.L., Dusza S.W., Benvenuto-Andrade C., Busam K.J., Myskowski P., and Halpern A.C. Dermatologic side effects associated with the epidermal growth factor receptor inhibitors. J Am Acad Dermatol 55 (2006) 657-670
5. Vano-Galvan S., Moreno-Martin P., and Jaén P. Progressive trichomegaly. Neth J Med 67 (2009) 35-36
6. Murillas R., Larcher F., Conti C.J., Santos M., Ullrich A., and Jorcano J.L. Expression of a dominant negative mutant of epidermal growth factor receptor in the epidermis of transgenic mice elicits striking alterations in hair follicle development and skin structure. EMBO J 14 (1995) 5216-5223
7. Montagut C., Grau J.J., Grimalt R., Codony J., Ferrando J., and Albanell J. Abnormal hair growth in a patient with head and neck cancer treated with the anti-epidermal growth factor receptor monoclonal antibody cetuximab. J Clin Oncol 23 (2005) 5273-5275
8. Kerob D., Dupuy A., Reygagne P., Levy A., Morel P., Bernard B.A., et al. Facial hypertrichosis induced by Cetuximab, an anti-EGFR monoclonal antibody. Arch Dermatol 142 (2006) 1656-1657