A manganese-porphyrin complex decomposes H 2O 2, inhibits apoptosis, and Acts as a radiation mitigator in vivo

ACS Medicinal Chemistry Letters

Volumn 2, Issue 11, 2011, Pages 814-817

  Stoyanovsky, Detcho A ^a   Huang, Zhentai ^a   Jiang, Jianfei ^a   Belikova, Natalia A ^a   Tyurin, Vladimir ^a   Epperly, Michael W ^b   Greenberger, Joel S ^b   Bayir, Hülya ^b   Kagan, Valerian E ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

apoptosis; H 2O 2; Manganese porphyrin complex; radiation mitigator

Indexed keywords

CATALASE; HYDROGEN PEROXIDE; MANGANESE DERIVATIVE; PORPHYRIN DERIVATIVE; TRIPHENYL [2 [4 [10,15,20 TRIS(4 AMINOPHENYL) 21,23 DIHYDROPORPHYRIN 5 YL]PHENYL]IMINOETHYL]PHOSPHONIUM MANGANESE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL COMPARTMENTALIZATION; CONTROLLED STUDY; EMBRYO; GAMMA RADIATION; IN VITRO STUDY; IN VIVO STUDY; IONIZING RADIATION; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION EXPOSURE; RADIOSENSITIVITY; SURVIVAL;

MUS;

EID: 80955128571     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml200142x     Document Type: Article

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