Aroclor 1254, a developmental neurotoxicant, alters energy metabolism- and intracellular signaling-associated protein networks in rat cerebellum and hippocampus

Toxicology and Applied Pharmacology

Volumn 256, Issue 3, 2011, Pages 290-299

  Kodavanti, Prasada Rao S ^a   Osorio, Cristina ^a,b   Royland, Joyce E ^a   Ramabhadran, Ram ^a   Alzate, Oscar ^b  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Calcium signaling; Cerebellum; Developmental neurotoxicity; Hippocampus; Molecular markers; PCB; Polychlorinated biphenyls; Proteomics; Quantitative Intact Proteomics

Indexed keywords

AROCLOR 1254; COLLAPSIN RESPONSE MEDIATOR PROTEIN; CREATINE KINASE; DIHYDROPYRIMIDINASE RELATED PROTEIN 4; MALATE DEHYDROGENASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; RYANODINE RECEPTOR 2; UNCLASSIFIED DRUG; VALOSIN CONTAINING PROTEIN; VOLTAGE DEPENDENT ANION CHANNEL 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CEREBELLUM; CONTROLLED STUDY; ENERGY METABOLISM; FEMALE; GESTATION PERIOD; HIPPOCAMPUS; INTRACELLULAR SIGNALING; NERVE CELL NETWORK; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; BLOTTING, WESTERN; CEREBELLUM; CHLORODIPHENYL (54% CHLORINE); DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENERGY METABOLISM; FEMALE; HIPPOCAMPUS; MITOCHONDRIA; NERVE TISSUE PROTEINS; NEUROTOXICITY SYNDROMES; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROTEOMICS; RATS; RATS, LONG-EVANS; SIGNAL TRANSDUCTION;

ANIMALIA; RATTUS;

EID: 80855147547     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.07.005     Document Type: Article

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