Ortho-substituted polychlorinated biphenyls alter calcium regulation by a ryanodine receptor-mediated mechanism: Structural specificity toward skeletal- and cardiac-type microsomal calcium release channels

Molecular Pharmacology

Volumn 49, Issue 4, 1996, Pages 740-751

  Wong, Patty W ^a   Pessah, Isaac N ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; POLYCHLORINATED BIPHENYL; RYANODINE RECEPTOR;

ANIMAL TISSUE; ARTICLE; CALCIUM METABOLISM; CALCIUM TRANSPORT; CHLORINATION; DRUG EFFICACY; DRUG POTENCY; EXCITATION CONTRACTION COUPLING; HEART MUSCLE; MICROSOME MEMBRANE; NONHUMAN; PRIORITY JOURNAL; RABBIT; SARCOPLASMIC RETICULUM; SKELETAL MUSCLE; STRUCTURE ACTIVITY RELATION;

ANIMALS; AROCLORS; CALCIUM; CALCIUM CHANNELS; MALE; MUSCLE PROTEINS; MUSCLE, SKELETAL; MYOCARDIUM; POLYCHLORINATED BIPHENYLS; RABBITS; RYANODINE; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029931969     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (56)

1. Hutzinger, O., S. Safe, and V. Zitko. The Chemistry of PCBs. CRC Press, Cleveland, OH (1974).
2. De Voogt, P., and U. A. T. Brinkman. Production, properties and usage of polychlorinated biphenyls, in Halogenated Biphenyls, Terphenyls, Naphthalenes, Dibenzodioxins and Related Products (R. D. Kimbrough and A. A. Jensen, eds.). 2nd Ed. Elsevier-North Holland, Amsterdam, 3-47 (1989).
3. Bush, B., A. H. Bennett, and J. T. Snow. Polychlorobiphenyl congeners, p,p′-DDE, and sperm function m humans. Arch. Environ. Contam. Toxicol. 15:333-341 (1986).
4. Buckley, E. H. Accumulation of airborne polychlorinated biphenyls in foliage. Science (Washington D. C.) 216:520-522 (1982).
5. Safe, S. Halogenated hydrocarbons and aryl hydrocarbons identified in human tissues. Toxicol. Environ. Chem. 5:153-165 (1982).
6. Ingebrigtsen, K., H. Hektoen, T. Andersson, A*. Bergman, and I. Brandt. Species-specific accumulation of the polychlorinated biphenyl (PCB) 2,3,3′,4,4′-pentachlorobiphenyl in fish brain: a comparison between cod (Gadus morhua) and rainbow trout (Oncorhychus mykiss). Pharmacol. Toxicol. 67:344-345 (1990).
7. Himberg, K., A. Hallikainen, and K. Louekari. Intake of polychlorinated biphenyls (PCB) from the Finnish diet. Z. Lebensm. Unters. Forsch. 196: 126-130 (1993).
8. Jensen, A. A. Polychlorobiphenyls (PCBs), polychlorodibenzo-p-dioxins (PCDDs) and polychlorodibenzofurans (PCDFs) in human milk, blood and adipose tissue. Sci. Total Environ. 64:259-293 (1987).
9. Kimbrough, R. D. Laboratory and human studies on polychlorinated biphenyls (PCBs) and related compounds. Environ. Health Perspect. 59:99-106 (1985).
10. Schwartz, P. M., S. W. Jacobson, G. Fein, J. L. Jacobson, and H. A. Price. Lake Michigan fish consumption as a source of polychlorinated biphenyls in human cord serum, maternal serum, and milk. Am. J. Public Health. 73:293-296 (1983).
11. Seegal, R. F., B. Bush, and K. O. Brosch. Sub-chronic exposure of the adult rat to Aroclor 1254 yields regionally-specific changes in central dopaminergic function. Neurotoxicology (Little Bock) 12:55-66 (1991).
12. Seegal, R. F., B. Bush, and W. Shain. Lightly chlorinated ortho-substituted PCB congeners decrease dopamine in nonhuman primate brain and in tissue culture. Toxicol. Appl. Pharmacol. 106:136-144 (1990).
13. Shain, W., B. Bush, and R. F. Seegal. Neurotoxicity of polychlorinated biphenyls: structure-activity relationship of individual congeners. Toxicol. Appl. Pharmacol. 111:33-42 (1991).
14. Nishida, N., J. D. Farmer, P. R. Kodavanti, H. A. Tilson, and R. C. MacPhail. Decreased motor activity produced by acute and repeated exposure to Aroclor 1254 in adult rats Toxicologist 15:189 (1995)
15. Kodavanti, P. R., D. Shin, H. A. Tilson, and G. J. Harry. Comparative effects of two polychlorinated biphenyl congeners on calcium homeostasis in rat cerebellar granule Cells. Toxicol. Appl. Pharmacol 123:97-106 (1993).
16. 3H]phorbol ester binding in rat cerebellar granule cells by polychlorinated biphenyl mixtures and congeners: structure-activity relationships. Toxicol. Appl. Pharmacol. 130:140-148 (1995).
17. 2+ release channel. J. Biol. Chem. 268:13765-13768 (1993).
18. Saito, A., S. Seiler, A. Chu, and S. Fleischer. Preparation and morphology of sarcoplasmic reticulum terminal cisternae from rabbit skeletal muscle. J. Cell Biol. 99:875-885 (1984).
19. 2+ uptake and ryanodine binding. J. Mol. Cell Cardiol. 23:249-258 (1991).
20. 2+ release. J. Biol. Chem. 267:20850-20856 (1992).
21. Ikemoto, N., B. Antoniu, J. J. Kang, L. G. Meszaros, and M. Ronjat. Intravesicular calcium transient during calcium release from sarcoplasmic reticulum. Biochemistry 30:5230-5237 (1991).
22. Caswell, A. H., N. R. Brandt, J. P. Brunschwig, and S. Purkerson. Localization and partial characterization of the oligomenc disulfide-linked molecular weight 95,000 protein (triadin) which binds the ryanodine and dihydropyridine receptors in skeletal muscle triadic vesicles. Biochemistry 30:7507-7513 (1991).
23. Knudson, C. M., K. K. Stang, A. O. Jorgensen, and K. P. Campbell. Biochemical characterization of ultrastructural localization of a major junctional sarcoplasmic reticulum glycoprotein (triadin). J. Biol. Chem. 268:12637-12645 (1993)
24. Timerman, A. P., E. Ogunbumni, E. Freund, G. Wiederrecht, A. R. Marks, and S. Fleischer. The calcium release channel of sarcoplasmic reticulum is modulated by FK-506-binding protein: dissociation and reconstitution of FKBP-12 to the calcium release channel of skeletal muscle sarcoplasmic reticulum. J. Biol. Chem. 268:22992-22999 (1993).
25. Mayrleitner, M., A. P. Timerman, L. Wiederrecht, and S. Fleischer. The calcium release channel of sarcoplasmic reticulum is modulated by FK-506 binding protein: effect of FKBP12 on single channel activity of the skeletal muscle ryanodine receptor. Cell Calcium 15:99-108 (1994).
26. Collins, J. H. Sequence analysis of the ryanodine receptor: possible association with a 12K, FK506-binding immunophilin/protein kinase C inhibitor. Biochem. Biophys. Res. Commun. 178:1288-1290 (1991).
27. Menegazzi, P., F. Larini, S. Treves, R. Guerrini, M. Quadroni, and F. Zorzato. Identification and characterization of three calmodulin binding sites of the skeletal muscle ryanodine receptor. Biochemistry 33:9078-9084 (1994).
28. 2+ release channel (ryanodine receptor) of rabbit skeletal muscle sarcoplasmic reticulum. J. Biol. Chem. 269:22698-22704 (1994).
29. Lowry, O. H., N. J. Rosebrough, A. L. Farr, and R. J. Randall. Protein measurement with folin phenol reagent. J Biol. Chem, 193:265-275 (1951).
30. 2+, caffeine, and adenine nucleotides. Mol. Pharmacol. 31:232-238 (1987).
31. Fabiato, A. Computer programs for calculating total from specified free or free from specified total ionic concentrations in aqueous solutions containing multiple metals and ligands. Methods Enzymol. 157:378-417 (1988).
32. 2+ release. J. Biol. Chem. 262:6135-6141 (1987).
33. 2+ release from rat cardiac and rabbit skeletal muscle sarcoplasmic reticulum. J. Pharmacol. Exp. Ther. 256:938-946 (1991).
34. +-adenosine triphosphatase in the mechanism of action of cardiac glycosides. J. Pharmacol. Exp. Ther. 168:31-41 (1969).
35. 2+ release channel of sarcoplasmic reticulum from skeletal and cardiac muscle: evidence for a sequential mechanism in ryanodine action. Mol. Pharmacol. 39:679-689 (1991).
36. Buck, E., I. Zimanyi, J. J. Abramson, and I. N. Pessah. Ryanodine stabilizes multiple conformational states of the skeletal muscle calcium release channel. J. Biol. Chem. 267:23560-23567 (1992).
37. Parkinson, A., and S. Safe. Mammalian Biologic and Toxic Effects of PCBs. Springer-Verlag, New York (1987).
38. Safe, S. Toxicology, structure-function relationship, and human and environmental health impacts of polychlorinated biphenyls: progress and problems. Environ. Health Perspect 100:259-268 (1992).
39. Silkworth, J. B., L. Antrim, and G. Sack. Ah receptor mediated suppression of the antibody response in mice is primarily dependent on the Ah phenotype of lymphoid tissue. Toxicol. Appl. Pharmacol. 86:380-390 (1986).
40. Hayes, M. A. Carcinogenic and Mutagenic Effects of PCBs. Springer-Verlag, New York (1987).
41. Ryan, D. E., P. E. Thomas, and W. Levin. Properties of purified liver microsomal cytochrome P-450 from rats treated with the polychlorinated biphenyl mixture Aroclor 1254. Mol. Pharmacol. 13:521-532 (1977).
42. Ryan, D. E., P. E. Thomas, D. Korzeniowski, and W. Levin. Separation and characterization of highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene. J. Biol. Chem. 254:1365-1374 (1979).
43. Buchmann, A., W. Kunz, C. R. Wolf, F. Oesch, and L. W. Robertson. Polychlorinated biphenyls, classified as either phenobarbital- or 3-methylcholanthrene-type inducers of cytochrome P-450, are both hepatic tumor promoters in diethylnitrosamine-initiated rats. Cancer Lett. 32:243-253 (1986).
44. Ledbetter, M. W., J. K. Preiner, C. F. Louis, and J. R. Mickelson. Tissue distribution of ryanodine receptor isoforms and alleles determined by reverse transcription polymerase chain reaction. J. Biol. Chem. 269: 31544-31551 (1994).
45. 2+ release channels are differentially expressed in rabbit brain. J. Neurosci. 14:4794-4805 (1994).
46. Tsien, R. W., D. Lipscombe, D. V. Madison, K. R. Bley, and A. P. Fox. Multiple types of neuronal calcium channels and their selective modulation. Trends Neurosci. 11:431-438 (1989).
47. Barnard, E. A. Receptor classes and the transmitter-gated ion channels. Trends Biochem. Sci. 17:368-374 (1992).
48. Berridge, M. J. Inositol trisphosphate and calcium signalling. Nature (Lond.) 361:315-325 (1993).
49. 2+ release channels and their regulation by endogenous effectors. Annu. Rev. Physiol. 56:485-508 (1994).
50. Zimmermann, H. Neurotransmitter release. FEBS. Lett. 268:394-399 (1990).
51. 2+ binding proteins and synaptic plasticity. Neurosci. Res. 16:1-7 (1993).
52. Bolgar, M., J. Cunningham, R. Cooper, R. Kozloski, and J. Huball. Physical, spectral and chromatographic properties of all 209 individual PCB congeners. Chemosphere 31:2678-2750 (1995).
53. Hutzinger, O., S. Safe, V. Zitko. The chemistry of PCB's. CRC Press, Cleveland (1974).
54. 2+ release channel from rat cardiac sarcoplasmic reticulum: possible receptor-mediated mechanism of doxorubicin cardiomyopathy. Mol. Pharmacol. 37:503-514 (1990).
55. Mack, M. M., T. F. Molinski, E. D. Buck, and I. N. Pessah. Novel modulators of the skeletal muscle sarcoplasmic reticulum calcium release channel complex from the marine sponge Ianthella basta: role of FKBP12 in channel activation. J. Biol. Chem. 269:23236-23249 (1994).
56. 2+ channels in excitable cells. Toxicologist, 30:226-227 (1996).