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Volumn 60, Issue 11, 2011, Pages 1071-1078

Associations between cytotoxic T lymphocyte-associated antigen-4 polymorphisms and serum tumor necrosis factor-α and interferon-γ levels in patients with chronic hepatitis B virus infection

Author keywords

Chronic HBV infection; Cytotoxic T lymphocyte associated antigen 4; Genetic polymorphism; Interferon ; Tumor necrosis factor

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; TUMOR NECROSIS FACTOR ALPHA;

EID: 80855138073     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-011-0368-8     Document Type: Article
Times cited : (9)

References (46)
  • 1
    • 1542316127 scopus 로고    scopus 로고
    • Hepatitis B Virus Infection - Natural History and Clinical Consequences
    • DOI 10.1056/NEJMra031087
    • D Ganem AM Prince 2004 Hepatitis B virus infection-natural history and clinical consequences N Engl J Med 350 1118 1129 15014185 10.1056/NEJMra031087 1:CAS:528:DC%2BD2cXitV2qurs%3D (Pubitemid 38298992)
    • (2004) New England Journal of Medicine , vol.350 , Issue.11 , pp. 1118-1129
    • Ganem, D.1    Prince, A.M.2
  • 2
    • 76249097154 scopus 로고    scopus 로고
    • Immune effectors required for hepatitis B virus clearance
    • 20080755 10.1073/pnas.0913498107 1:CAS:528:DC%2BC3cXhtFCmsLw%3D
    • PL Yang A Althage J Chung H Maier S Wieland M Isogawa, et al. 2010 Immune effectors required for hepatitis B virus clearance Proc Natl Acad Sci USA 107 798 802 20080755 10.1073/pnas.0913498107 1:CAS:528:DC%2BC3cXhtFCmsLw%3D
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 798-802
    • Yang, P.L.1    Althage, A.2    Chung, J.3    Maier, H.4    Wieland, S.5    Isogawa, M.6
  • 3
    • 0037213545 scopus 로고    scopus 로고
    • + T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection
    • DOI 10.1128/JVI.77.1.68-76.2003
    • R Thimme S Wieland C Steiger J Ghrayeb KA Reimann RH Purcell, et al. 2003 CD8(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection J Virol 77 68 76 12477811 10.1128/JVI.77.1.68-76. 2003 1:CAS:528:DC%2BD3sXkt1Sn (Pubitemid 36004947)
    • (2003) Journal of Virology , vol.77 , Issue.1 , pp. 68-76
    • Thimme, R.1    Wieland, S.2    Steiger, C.3    Ghrayeb, J.4    Reimann, K.A.5    Purcell, R.H.6    Chisari, F.V.7
  • 5
    • 0345306198 scopus 로고    scopus 로고
    • Role of hepatitis B virus specific cytotoxic T cells in liver damage and viral control
    • DOI 10.1016/j.antiviral.2003.08.012
    • A Bertoletti M Maini R Williams 2003 Role of hepatitis B virus specific cytotoxic T cells in liver damage and viral control Antiviral Res 60 61 66 14638399 10.1016/j.antiviral.2003.08.012 1:CAS:528:DC%2BD3sXpt1eqsr4%3D (Pubitemid 37452447)
    • (2003) Antiviral Research , vol.60 , Issue.2 , pp. 61-66
    • Bertoletti, A.1    Maini, M.2    Williams, R.3
  • 6
    • 0037325472 scopus 로고    scopus 로고
    • Immune responses in hepatitis B virus infection
    • 12616448 10.1055/s-2003-37586 1:CAS:528:DC%2BD3sXisFamtrs%3D
    • B Rehermann 2003 Immune responses in hepatitis B virus infection Semin Liver Dis 23 21 38 12616448 10.1055/s-2003-37586 1:CAS:528:DC%2BD3sXisFamtrs%3D
    • (2003) Semin Liver Dis , vol.23 , pp. 21-38
    • Rehermann, B.1
  • 7
    • 0027979128 scopus 로고
    • Interleukin-2 and alpha/beta interferon down-regulate hepatitis B virus gene expression in vivo by tumor necrosis factor-dependent and -independent pathways
    • LG Guidotti S Guilhot FV Chisari 1994 Interleukin-2 and alpha/beta interferon down-regulate hepatitis B virus gene expression in vivo by tumor necrosis factor-dependent and -independent pathways J Virol 68 1265 1270 8107192 1:CAS:528:DyaK2cXhvV2mu74%3D (Pubitemid 24065687)
    • (1994) Journal of Virology , vol.68 , Issue.3 , pp. 1265-1270
    • Guidotti, L.G.1    Guilhot, S.2    Chisari, F.V.3
  • 8
    • 33745727513 scopus 로고    scopus 로고
    • The immune response induced by hepatitis B virus principal antigens
    • 16696896 1:CAS:528:DC%2BD28XlvVSqtb0%3D
    • CF Huang SS Lin YC Ho FL Chen CC Yang 2006 The immune response induced by hepatitis B virus principal antigens Cell Mol Immunol 3 97 106 16696896 1:CAS:528:DC%2BD28XlvVSqtb0%3D
    • (2006) Cell Mol Immunol , vol.3 , pp. 97-106
    • Huang, C.F.1    Lin, S.S.2    Ho, Y.C.3    Chen, F.L.4    Yang, C.C.5
  • 9
    • 0035421654 scopus 로고    scopus 로고
    • + immunoregulatory cells
    • CA Piccirillo EM Shevach 2001 Cutting edge: control of CD8+ T cell activation by CD4+ CD25+ immunoregulatory cells J Immunol 167 1137 1140 11466326 1:CAS:528:DC%2BD3MXls1WktL0%3D (Pubitemid 32703105)
    • (2001) Journal of Immunology , vol.167 , Issue.3 , pp. 1137-1140
    • Piccirillo, C.A.1    Shevach, E.M.2
  • 10
    • 0035185411 scopus 로고    scopus 로고
    • + suppressor T cells
    • DOI 10.1034/j.1600-065X.2001.1820104.x
    • EM Shevach RS McHugh CA Piccirillo AM Thornton 2001 Control of T-cell activation by CD4+ CD25+ suppressor T cells Immunol Rev 182 58 67 11722623 10.1034/j.1600-065X.2001.1820104.x 1:CAS:528:DC%2BD3MXpt1eisL8%3D (Pubitemid 33070207)
    • (2001) Immunological Reviews , vol.182 , pp. 58-67
    • Shevach, E.M.1    McHugh, R.S.2    Piccirillo, C.A.3    Thornton, A.M.4
  • 12
    • 37149016672 scopus 로고    scopus 로고
    • + regulatory T cells correlate with chronic hepatitis B infection
    • DOI 10.1111/j.1365-2567.2007.02691.x
    • G Peng S Li W Wu Z Sun Y Chen Z Chen 2008 Circulating CD4+ CD25+ regulatory T cells correlate with chronic hepatitis B infection Immunology 123 57 65 17764450 10.1111/j.1365-2567.2007.02691.x 1:CAS:528:DC%2BD1cXnsFWjsg%3D%3D (Pubitemid 350255997)
    • (2008) Immunology , vol.123 , Issue.1 , pp. 57-65
    • Peng, G.1    Li, S.2    Wu, W.3    Sun, Z.4    Chen, Y.5    Chen, Z.6
  • 13
    • 16244385911 scopus 로고    scopus 로고
    • Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection
    • DOI 10.1002/hep.20649
    • JN Stoop RG van der Molen CC Baan LJ van der Laan EJ Kuipers JG Kusters, et al. 2005 Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection Hepatology 41 771 778 15791617 10.1002/hep.20649 1:CAS:528:DC%2BD2MXjsV2msLs%3D (Pubitemid 40462939)
    • (2005) Hepatology , vol.41 , Issue.4 , pp. 771-778
    • Stoop, J.N.1    Van Der Molen, R.G.2    Baan, C.C.3    Van Der Laan, L.J.W.4    Kuipers, E.J.5    Kusters, J.G.6    Janssen, H.L.A.7
  • 14
    • 0034254301 scopus 로고    scopus 로고
    • CTLA-4 (CD152) can inhibit T cell activation by two different mechanisms depending on its level of cell surface expression
    • BM Carreno F Bennett TA Chau V Ling D Luxenberg J Jussif, et al. 2000 CTLA-4 (CD152) can inhibit T cell activation by two different mechanisms depending on its level of cell surface expression J Immunol 165 1352 1356 10903737 1:STN:280:DC%2BD3cvgsFejtQ%3D%3D (Pubitemid 30604565)
    • (2000) Journal of Immunology , vol.165 , Issue.3 , pp. 1352-1356
    • Carreno, B.M.1    Bennett, F.2    Chau, T.A.3    Ling, V.4    Luxenberg, D.5    Jussif, J.6    Baroja, M.L.7    Madrenas, J.8
  • 15
    • 67649518924 scopus 로고    scopus 로고
    • CTLA-4 is required by CD4+CD25+ Treg to control CD4+ T-cell lymphopenia-induced proliferation
    • 19462377 10.1002/eji.200838603 1:CAS:528:DC%2BD1MXntFCitLc%3D
    • DK Sojka A Hughson DJ Fowell 2009 CTLA-4 is required by CD4+CD25+ Treg to control CD4+ T-cell lymphopenia-induced proliferation Eur J Immunol 39 1544 1551 19462377 10.1002/eji.200838603 1:CAS:528:DC%2BD1MXntFCitLc%3D
    • (2009) Eur J Immunol , vol.39 , pp. 1544-1551
    • Sojka, D.K.1    Hughson, A.2    Fowell, D.J.3
  • 16
    • 0033019735 scopus 로고    scopus 로고
    • CTLA-4 and T cell activation
    • DOI 10.1016/S0952-7915(99)80047-8
    • MA Oosterwegel RJ Greenwald DA Mandelbrot RB Lorsbach AH Sharpe 1999 CTLA-4 and T cell activation Curr Opin Immunol 11 294 300 10375557 10.1016/S0952-7915(99)80047-8 1:CAS:528:DyaK1MXjvVKjtbc%3D (Pubitemid 29263957)
    • (1999) Current Opinion in Immunology , vol.11 , Issue.3 , pp. 294-300
    • Oosterwegel, M.A.1
  • 17
    • 0028949152 scopus 로고
    • B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy
    • 7534215 10.1016/0092-8674(95)90349-6 1:CAS:528:DyaK2MXksVahs78%3D
    • VK Kuchroo MP Das JA Brown AM Ranger SS Zamvil RA Sobel, et al. 1995 B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy Cell 80 707 718 7534215 10.1016/0092-8674(95)90349-6 1:CAS:528:DyaK2MXksVahs78%3D
    • (1995) Cell , vol.80 , pp. 707-718
    • Kuchroo, V.K.1    Das, M.P.2    Brown, J.A.3    Ranger, A.M.4    Zamvil, S.S.5    Sobel, R.A.6
  • 18
    • 64049116467 scopus 로고    scopus 로고
    • CD152 (CTLA-4) regulates effector functions of CD8+ T lymphocytes by repressing Eomesodermin
    • 19224637 10.1002/eji.200838770 1:CAS:528:DC%2BD1MXktVaitr4%3D
    • JK Hegel K Knieke P Kolar SL Reiner MC Brunner-Weinzierl 2009 CD152 (CTLA-4) regulates effector functions of CD8+ T lymphocytes by repressing Eomesodermin Eur J Immunol 39 883 893 19224637 10.1002/eji.200838770 1:CAS:528:DC%2BD1MXktVaitr4%3D
    • (2009) Eur J Immunol , vol.39 , pp. 883-893
    • Hegel, J.K.1    Knieke, K.2    Kolar, P.3    Reiner, S.L.4    Brunner-Weinzierl, M.C.5
  • 19
    • 33846940484 scopus 로고    scopus 로고
    • High IFN-γ production of individual CD8 T lymphocytes is controlled by CD152 (CTLA-4)
    • P Pandiyan JK Hegel M Krueger D Quandt MC Brunner-Weinzierl 2007 High IFN-gamma production of individual CD8 T lymphocytes is controlled by CD152 (CTLA-4) J Immunol 178 2132 2140 17277117 1:CAS:528:DC%2BD2sXht1Cgurk%3D (Pubitemid 46233410)
    • (2007) Journal of Immunology , vol.178 , Issue.4 , pp. 2132-2140
    • Pandiyan, P.1    Hegel, J.K.E.2    Krueger, M.3    Quandt, D.4    Brunner-Weinzierl, M.C.5
  • 20
    • 0033731186 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates the size, reactivity, and function of a primed pool of CD4+ T cells
    • 11050166 10.1073/pnas.220423597 1:CAS:528:DC%2BD3cXotFynsb0%3D
    • MS Kuhns V Epshteyn RA Sobel JP Allison 2000 Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates the size, reactivity, and function of a primed pool of CD4+ T cells Proc Natl Acad Sci USA 97 12711 12716 11050166 10.1073/pnas.220423597 1:CAS:528:DC%2BD3cXotFynsb0%3D
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12711-12716
    • Kuhns, M.S.1    Epshteyn, V.2    Sobel, R.A.3    Allison, J.P.4
  • 21
    • 0034661995 scopus 로고    scopus 로고
    • Indispensable role for TNF-α and IFN-γ at the effector phase of liver injury mediated by Th1 cells specific to hepatitis B virus surface antigen
    • A Ohta M Sekimoto M Sato T Koda S Nishimura Y Iwakura, et al. 2000 Indispensable role for TNF-alpha and IFN-gamma at the effector phase of liver injury mediated by Th1 cells specific to hepatitis B virus surface antigen J Immunol 165 956 961 10878371 1:CAS:528:DC%2BD3cXkvFWitro%3D (Pubitemid 30484764)
    • (2000) Journal of Immunology , vol.165 , Issue.2 , pp. 956-961
    • Ohta, A.1    Sekimoto, M.2    Sato, M.3    Koda, T.4    Nishimura, S.-I.5    Iwakura, Y.6    Sekikawa, K.7    Nishimura, T.8
  • 22
    • 0037320085 scopus 로고    scopus 로고
    • Lack of tumor necrosis factor alpha induces impaired proliferation of hepatitis B virus-specific cytotoxic T lymphocytes
    • DOI 10.1128/JVI.77.4.2469-2476.2003
    • S Kasahara K Ando K Saito K Sekikawa H Ito T Ishikawa, et al. 2003 Lack of tumor necrosis factor alpha induces impaired proliferation of hepatitis B virus-specific cytotoxic T lymphocytes J Virol 77 2469 2476 12551985 10.1128/JVI.77.4.2469-2476.2003 1:CAS:528:DC%2BD3sXpvVGntQ%3D%3D (Pubitemid 36222771)
    • (2003) Journal of Virology , vol.77 , Issue.4 , pp. 2469-2476
    • Kasahara, S.1    Ando, K.2    Saito, K.3    Sekikawa, K.4    Ito, H.5    Ishikawa, T.6    Ohnishi, H.7    Seishima, M.8    Kakumu, S.9    Moriwaki, H.10
  • 23
    • 34548796457 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha inhibits the suppressive effect of regulatory T cells on the hepatitis B virus-specific immune response
    • DOI 10.1002/hep.21761
    • JN Stoop AM Woltman PJ Biesta JG Kusters EJ Kuipers HL Janssen, et al. 2007 Tumor necrosis factor alpha inhibits the suppressive effect of regulatory T cells on the hepatitis B virus-specific immune response Hepatology 46 699 705 17654744 10.1002/hep.21761 1:CAS:528:DC%2BD2sXhtFWhsrzF (Pubitemid 47436115)
    • (2007) Hepatology , vol.46 , Issue.3 , pp. 699-705
    • Stoop, J.N.1    Woltman, A.M.2    Biesta, P.J.3    Kusters, J.G.4    Kuipers, E.J.5    Janssen, H.L.A.6    Van Der Molen, R.G.7
  • 24
    • 4344658402 scopus 로고    scopus 로고
    • Induction and regulation of IFNs during viral infections
    • DOI 10.1089/1079990041689665
    • L Malmgaard 2004 Induction and regulation of IFNs during viral infections J Interferon Cytokine Res 24 439 454 15320958 10.1089/1079990041689665 1:CAS:528:DC%2BD2cXms12jt74%3D (Pubitemid 39120592)
    • (2004) Journal of Interferon and Cytokine Research , vol.24 , Issue.8 , pp. 439-454
    • Malmgaard, L.1
  • 25
    • 0035346140 scopus 로고    scopus 로고
    • CTLA-4 gene expression is influenced by promoter and exon 1 polymorphisms
    • DOI 10.1038/sj.gene.6363752
    • A Ligers N Teleshova T Masterman WX Huang J Hillert 2001 CTLA-4 gene expression is influenced by promoter and exon 1 polymorphisms Genes Immun 2 145 152 11426323 10.1038/sj.gene.6363752 1:CAS:528:DC%2BD3MXksVyisbc%3D (Pubitemid 33674879)
    • (2001) Genes and Immunity , vol.2 , Issue.3 , pp. 145-152
    • Ligers, A.1    Teleshova, N.2    Masterman, T.3    Huang, W.-X.4    Hillert, J.5
  • 26
    • 0036256007 scopus 로고    scopus 로고
    • A polymorphism in the human cytotoxic T-lymphocyte antigen 4 (CTLA4) gene (exon 1 +49) alters T-cell activation
    • DOI 10.1007/s00251-002-0429-9
    • M Mäurer S Loserth A Kolb-Mäurer A Ponath S Wiese N Kruse, et al. 2002 A polymorphism in the human cytotoxic T-lymphocyte antigen 4 (CTLA4) gene (exon 1 +49) alters T-cell activation Immunogenetics 54 1 8 11976786 10.1007/s00251-002-0429-9 (Pubitemid 34492947)
    • (2002) Immunogenetics , vol.54 , Issue.1 , pp. 1-8
    • Maurer, M.1    Loserth, S.2    Kolb-Maurer, A.3    Ponath, A.4    Wiese, S.5    Kruse, N.6    Rieckmann, P.7
  • 27
    • 0036615259 scopus 로고    scopus 로고
    • A CTLA-4 gene polymorphism at position -318 in the promoter region affects the expression of protein
    • DOI 10.1038/sj.gene.6363869
    • XB Wang X Zhao R Giscombe AK Lefvert 2002 A CTLA-4 gene polymorphism at position -318 in the promoter region affects the expression of protein Genes Immun 3 233 234 12058260 10.1038/sj.gene.6363869 (Pubitemid 38961137)
    • (2002) Genes and Immunity , vol.3 , Issue.4 , pp. 233-234
    • Wang, X.B.1    Zhao, X.2    Giscombe, R.3    Lefvert, A.K.4
  • 29
    • 84855237235 scopus 로고    scopus 로고
    • CTLA-4 exon 1 +49 polymorphism alone and in a haplotype with -318 promoter polymorphism may confer susceptibility to chronic HBV infection in Chinese Han patients
    • DOI: 10.1007/s11033-010-0660-7
    • Duan S, Zhang G, Han Q, Li Z, Liu Z, Chen J, et al. CTLA-4 exon 1 +49 polymorphism alone and in a haplotype with -318 promoter polymorphism may confer susceptibility to chronic HBV infection in Chinese Han patients. Mol Biol Rep. 2010; DOI: 10.1007/s11033-010-0660-7.
    • (2010) Mol Biol Rep.
    • Duan, S.1    Zhang, G.2    Han, Q.3    Li, Z.4    Liu, Z.5    Chen, J.6
  • 30
    • 0000594889 scopus 로고    scopus 로고
    • Infectious and Parasitic Diseases Branch and Hepatology Branch. Viral hepatitis prevention and treatment guidelines
    • Chinese Medical Association
    • Chinese Medical Association 2000 Infectious and Parasitic Diseases Branch and Hepatology Branch. Viral hepatitis prevention and treatment guidelines Chin J Hepatol 8 324 329
    • (2000) Chin J Hepatol , vol.8 , pp. 324-329
  • 31
    • 33744496666 scopus 로고    scopus 로고
    • The clinical diagnosis and staging criteria of primary hepatic carcinoma
    • Chinese Anticancer Society of Hepatoma Professional Board
    • Chinese Anticancer Society of Hepatoma Professional Board 2001 The clinical diagnosis and staging criteria of primary hepatic carcinoma Chin J Hepatol 9 324
    • (2001) Chin J Hepatol , vol.9 , pp. 324
  • 32
    • 64149129845 scopus 로고    scopus 로고
    • A partition-ligation-combination-subdivision em algorithm for haplotype inference with multiallelic markers: Update of the SHEsis
    • Li Z, Zhang Z, He Z, Tang W, Li T, Zeng Z, et al. A partition-ligation- combination-subdivision EM algorithm for haplotype inference with multiallelic markers: update of the SHEsis ( http://analysis.bio-x.cn ). Cell Res. 2009;19:519-23.
    • (2009) CellRes , vol.19 , pp. 519-523
    • Li, Z.1    Zhang, Z.2    He, Z.3    Tang, W.4    Li, T.5    Zeng, Z.6
  • 33
    • 0036284203 scopus 로고    scopus 로고
    • Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals
    • DOI 10.1159/000057986
    • DV Zaykin PH Westfall SS Young MA Karnoub MJ Wagner MG Ehm 2002 Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals Hum Hered 53 79 91 12037407 10.1159/000057986 (Pubitemid 34621657)
    • (2002) Human Heredity , vol.53 , Issue.2 , pp. 79-91
    • Zaykin, D.V.1    Westfall, P.H.2    Young, S.S.3    Karnoub, M.A.4    Wagner, M.J.5    Ehm, M.G.6
  • 34
    • 70349964671 scopus 로고    scopus 로고
    • Haplotypes in the UGT1A1 gene and their role as genetic determinants of bilirubin concentration in healthy German volunteers
    • 19732760 10.1016/j.clinbiochem.2009.08.011 1:CAS:528:DC%2BD1MXht1CqsrfJ
    • K Borucki C Weikert E Fisher S Jakubiczka C Luley S Westphal, et al. 2009 Haplotypes in the UGT1A1 gene and their role as genetic determinants of bilirubin concentration in healthy German volunteers Clin Biochem 42 1635 1641 19732760 10.1016/j.clinbiochem.2009.08.011 1:CAS:528:DC%2BD1MXht1CqsrfJ
    • (2009) Clin Biochem , vol.42 , pp. 1635-1641
    • Borucki, K.1    Weikert, C.2    Fisher, E.3    Jakubiczka, S.4    Luley, C.5    Westphal, S.6
  • 35
    • 0025977773 scopus 로고
    • Increased production of tumour necrosis factor alpha in chronic hepatitis B virus infection
    • 2051003 10.1016/0168-8278(91)90945-8 1:STN:280:DyaK3M3mvVCqsg%3D%3D
    • N Sheron J Lau H Daniels J Goka A Eddleston GJ Alexander, et al. 1991 Increased production of tumour necrosis factor alpha in chronic hepatitis B virus infection J Hepatol 12 241 245 2051003 10.1016/0168-8278(91)90945-8 1:STN:280:DyaK3M3mvVCqsg%3D%3D
    • (1991) J Hepatol , vol.12 , pp. 241-245
    • Sheron, N.1    Lau, J.2    Daniels, H.3    Goka, J.4    Eddleston, A.5    Alexander, G.J.6
  • 36
    • 0028215964 scopus 로고
    • Selective expansion of cytotoxic T lymphocytes with a CD4+CD56+ surface phenotype and a T helper type 1 profile of cytokine secretion in the liver of patients chronically infected with Hepatitis B virus
    • 7511637 1:CAS:528:DyaK2cXis1Oqurc%3D
    • V Barnaba A Franco M Paroli R Benvenuto G De Petrillo VL Burgio, et al. 1994 Selective expansion of cytotoxic T lymphocytes with a CD4+CD56+ surface phenotype and a T helper type 1 profile of cytokine secretion in the liver of patients chronically infected with Hepatitis B virus J Immunol 152 3074 3087 7511637 1:CAS:528:DyaK2cXis1Oqurc%3D
    • (1994) J Immunol , vol.152 , pp. 3074-3087
    • Barnaba, V.1    Franco, A.2    Paroli, M.3    Benvenuto, R.4    De Petrillo, G.5    Burgio, V.L.6
  • 37
    • 0026691627 scopus 로고
    • Serum levels of cytokines in chronic liver diseases
    • 1612333 1:CAS:528:DyaK38XkvVOrt7s%3D
    • H Tilg A Wilmer W Vogel M Herold B Nölchen G Judmaier, et al. 1992 Serum levels of cytokines in chronic liver diseases Gastroenterology 103 264 274 1612333 1:CAS:528:DyaK38XkvVOrt7s%3D
    • (1992) Gastroenterology , vol.103 , pp. 264-274
    • Tilg, H.1    Wilmer, A.2    Vogel, W.3    Herold, M.4    Nölchen, B.5    Judmaier, G.6
  • 38
    • 0030021968 scopus 로고    scopus 로고
    • Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes
    • DOI 10.1016/S1074-7613(00)80295-2
    • LG Guidotti T Ishikawa MV Hobbs B Matzke R Schreiber FV Chisari 1996 Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes Immunity 4 25 36 8574849 10.1016/S1074-7613(00)80295-2 1:CAS:528: DyaK28Xos1Kltw%3D%3D (Pubitemid 26054933)
    • (1996) Immunity , vol.4 , Issue.1 , pp. 25-36
    • Guidotti, L.G.1    Ishikawa, T.2    Hobbs, M.V.3    Matzke, B.4    Schreiber, R.5    Chisari, F.V.6
  • 39
    • 73949152609 scopus 로고    scopus 로고
    • CD8(+) T cell control of hepatitis B virus replication: Direct comparison between cytolytic and noncytolytic functions
    • 19949099 10.4049/jimmunol.0902761 1:CAS:528:DC%2BD1MXhsFOnsLjL
    • S Phillips S Chokshi A Riva A Evans R Williams NV Naoumov 2010 CD8(+) T cell control of hepatitis B virus replication: direct comparison between cytolytic and noncytolytic functions J Immunol 184 287 295 19949099 10.4049/jimmunol.0902761 1:CAS:528:DC%2BD1MXhsFOnsLjL
    • (2010) J Immunol , vol.184 , pp. 287-295
    • Phillips, S.1    Chokshi, S.2    Riva, A.3    Evans, A.4    Williams, R.5    Naoumov, N.V.6
  • 41
    • 35148869631 scopus 로고    scopus 로고
    • Recipient cytotoxic T lymphocyte antigen-4 +49 G/G genotype is associated with reduced incidence of hepatitis B virus recurrence after liver transplantation among Chinese patients
    • DOI 10.1111/j.1478-3231.2007.01553.x
    • Z Jiang X Feng W Zhang F Gao Q Ling L Zhou, et al. 2007 Recipient cytotoxic T lymphocyte antigen-4 +49 G/G genotype is associated with reduced incidence of hepatitis B virus recurrence after liver transplantation among Chinese patients Liver Int 27 1202 1208 17919231 1:CAS:528:DC%2BD2sXhtlalu7jI (Pubitemid 47543148)
    • (2007) Liver International , vol.27 , Issue.9 , pp. 1202-1208
    • Jiang, Z.1    Feng, X.2    Zhang, W.3    Gao, F.4    Ling, Q.5    Zhou, L.6    Xie, H.7    Chen, Q.8    Zheng, S.9
  • 42
    • 0034548720 scopus 로고    scopus 로고
    • CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease
    • 11086105 1:CAS:528:DC%2BD3cXosFOhtr4%3D
    • T Kouki Y Sawai CA Gardine ME Fisfalen ML Alegre LJ DeGroot 2000 CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease J Immunol 165 6606 6611 11086105 1:CAS:528:DC%2BD3cXosFOhtr4%3D
    • (2000) J Immunol , vol.165 , pp. 6606-6611
    • Kouki, T.1    Sawai, Y.2    Gardine, C.A.3    Fisfalen, M.E.4    Alegre, M.L.5    Degroot, L.J.6
  • 43
    • 14544271524 scopus 로고    scopus 로고
    • Definition and clinical importance of haplotypes
    • DOI 10.1146/annurev.med.56.082103.104540
    • DC Crawford DA Nickerson 2005 Definition and clinical importance of haplotypes Annu Rev Med 56 303 320 15660514 10.1146/annurev.med.56.082103.104540 1:CAS:528:DC%2BD2MXisVSrsbc%3D (Pubitemid 40299785)
    • (2005) Annual Review of Medicine , vol.56 , pp. 303-320
    • Crawford, D.C.1    Nickerson, D.A.2
  • 44
    • 34547947975 scopus 로고    scopus 로고
    • Haplotype analysis can provide improved clinical information than single genotype analysis
    • DOI 10.1016/j.thromres.2006.08.013, PII S0049384806003884
    • VC Sandrim JE Tanus-Santos 2007 Haplotype analysis can provide improved clinical information than single genotype analysis Thromb Res 120 779 17174381 10.1016/j.thromres.2006.08.013 1:CAS:528:DC%2BD2sXpsFKrt7k%3D (Pubitemid 47268038)
    • (2007) Thrombosis Research , vol.120 , Issue.5 , pp. 779
    • Sandrim, V.C.1    Tanus-Santos, J.E.2
  • 46
    • 0035451084 scopus 로고    scopus 로고
    • Technical note: Linkage disequilibrium and disease-associated CTLA4 gene polymorphisms
    • PM Holopainen JA Partanen 2001 Technical note: linkage disequilibrium and disease-associated CTLA4 gene polymorphisms J Immunol 167 2457 2458 11509583 1:CAS:528:DC%2BD3MXmtlSjsb4%3D (Pubitemid 32768870)
    • (2001) Journal of Immunology , vol.167 , Issue.5 , pp. 2457-2458
    • Holopainen, P.M.1    Partanen, J.A.2


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