-
2
-
-
0035757397
-
T-cell regulation by CD28 and CTLA-4
-
Alegre, M. L., Frauwirth, K. A. and Thompson, C. B., T-cell regulation by CD28 and CTLA-4. Nat. Rev. Immunol. 2001. 1: 220-228.
-
(2001)
Nat. Rev. Immunol
, vol.1
, pp. 220-228
-
-
Alegre, M.L.1
Frauwirth, K.A.2
Thompson, C.B.3
-
3
-
-
0027282960
-
Characterization of CTLA-4 structure and expression on human T cells
-
Lindsten, T., Lee, K. P., Harris, E. S., Petryniak, B., Craighead, N., Reynolds, P. J., Lombard, D. B. et al., Characterization of CTLA-4 structure and expression on human T cells. J. Immunol. 1993. 151: 3489-3499.
-
(1993)
J. Immunol
, vol.151
, pp. 3489-3499
-
-
Lindsten, T.1
Lee, K.P.2
Harris, E.S.3
Petryniak, B.4
Craighead, N.5
Reynolds, P.J.6
Lombard, D.B.7
-
4
-
-
0031054242
-
CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics
-
van der Merwe, P. A., Bodian, D. L., Daenke, S., Linsley, P. and Davis, S. J., CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics. J. Exp. Med. 1997. 185: 393-403.
-
(1997)
J. Exp. Med
, vol.185
, pp. 393-403
-
-
van der Merwe, P.A.1
Bodian, D.L.2
Daenke, S.3
Linsley, P.4
Davis, S.J.5
-
5
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
-
Waterhouse, P., Penninger, J. M., Timms, E.,Wakeham, A., Shahinian, A., Lee, K. P., Thompson, C. B. et al., Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science 1995. 270: 985-988.
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
Wakeham, A.4
Shahinian, A.5
Lee, K.P.6
Thompson, C.B.7
-
7
-
-
0030707866
-
Cytotoxic T lymphocyte antigen 4 (CTLA-4) interferes with extracellular signal-regulated kinase (ERK) and Jun NH2-terminal kinase (JNK) activation, but does not affect phosphorylation of T cell receptor zeta and ZAP70
-
Calvo, C. R., Amsen, D. and Kruisbeek, A. M., Cytotoxic T lymphocyte antigen 4 (CTLA-4) interferes with extracellular signal-regulated kinase (ERK) and Jun NH2-terminal kinase (JNK) activation, but does not affect phosphorylation of T cell receptor zeta and ZAP70. J. Exp. Med. 1997. 186: 1645-1653.
-
(1997)
J. Exp. Med
, vol.186
, pp. 1645-1653
-
-
Calvo, C.R.1
Amsen, D.2
Kruisbeek, A.M.3
-
8
-
-
0029947568
-
Enhancement of antitumor immunity by CTLA-4 blockade
-
Leach, D. R., Krummel, M. F. and Allison, J. P., Enhancement of antitumor immunity by CTLA-4 blockade. Science 1996. 271: 1734-1736.
-
(1996)
Science
, vol.271
, pp. 1734-1736
-
-
Leach, D.R.1
Krummel, M.F.2
Allison, J.P.3
-
9
-
-
33846940484
-
High IFN-{gamma} production of individual CD8 T lymphocytes is controlled by CD152 (CTLA-4)
-
Pandiyan, P., Hegel, J. K., Krueger, M., Quandt, D. and Brunner-Weinzierl, M. C., High IFN-{gamma} production of individual CD8 T lymphocytes is controlled by CD152 (CTLA-4). J. Immunol. 2007. 178: 2132-2140.
-
(2007)
J. Immunol
, vol.178
, pp. 2132-2140
-
-
Pandiyan, P.1
Hegel, J.K.2
Krueger, M.3
Quandt, D.4
Brunner-Weinzierl, M.C.5
-
12
-
-
17944364189
-
Elucidating the autoimmune an antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: Comparison of prophylaxis and therapy
-
van Elsas, A., Sutmuller, R. P., Hurwitz, A. A., Ziskin, J., Villasenor, J., Medema, J. P., Overwijk, W. W. et al., Elucidating the autoimmune an antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: Comparison of prophylaxis and therapy. J. Exp. Med. 2001. 194: 481-489.
-
(2001)
J. Exp. Med
, vol.194
, pp. 481-489
-
-
van Elsas, A.1
Sutmuller, R.P.2
Hurwitz, A.A.3
Ziskin, J.4
Villasenor, J.5
Medema, J.P.6
Overwijk, W.W.7
-
13
-
-
0036301503
-
CTLA-4: New insights into its biological function and use in tumor immunotherapy
-
Egen, J. G., Kuhns, M. S. and Allison, J. P., CTLA-4: New insights into its biological function and use in tumor immunotherapy. Nat. Immunol. 2002. 3: 611-618.
-
(2002)
Nat. Immunol
, vol.3
, pp. 611-618
-
-
Egen, J.G.1
Kuhns, M.S.2
Allison, J.P.3
-
14
-
-
0344341626
-
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
-
Hodi, F. S., Mihm, M. C., Soiffer, R. J., Haluska, F. G., Butler, M., Seiden, M. V., Davis, T. et al., Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients. Proc. Natl. Acad. Sci. USA 2003. 100: 4712-4717.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 4712-4717
-
-
Hodi, F.S.1
Mihm, M.C.2
Soiffer, R.J.3
Haluska, F.G.4
Butler, M.5
Seiden, M.V.6
Davis, T.7
-
15
-
-
8544234990
-
Recent developments in the transcriptional regulation of cytolytic effector cells
-
Glimcher, L. H., Townsend, M. J., Sullivan, B. M. and Lord, G. M., Recent developments in the transcriptional regulation of cytolytic effector cells. Nat. Rev. Immunol. 2004. 4: 900-911.
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 900-911
-
-
Glimcher, L.H.1
Townsend, M.J.2
Sullivan, B.M.3
Lord, G.M.4
-
18
-
-
1842785209
-
T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells
-
Townsend, M. J., Weinmann, A. S., Matsuda, J. L., Salomon, R., Farnham, P. J., Biron, C. A., Gapin, L. et al., T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells. Immunity 2004. 20: 477-494.
-
(2004)
Immunity
, vol.20
, pp. 477-494
-
-
Townsend, M.J.1
Weinmann, A.S.2
Matsuda, J.L.3
Salomon, R.4
Farnham, P.J.5
Biron, C.A.6
Gapin, L.7
-
19
-
-
0030582733
-
Eomesodermin, a key early gene in Xenopus mesoderm differentiation
-
Ryan, K., Garrett, N., Mitchell, A. and Gurdon, J. B., Eomesodermin, a key early gene in Xenopus mesoderm differentiation. Cell 1996. 87: 989-1000.
-
(1996)
Cell
, vol.87
, pp. 989-1000
-
-
Ryan, K.1
Garrett, N.2
Mitchell, A.3
Gurdon, J.B.4
-
20
-
-
17544368153
-
Eomesodermin is required for mouse trophoblast development and mesoderm formation
-
Russ, A. P.,Wattler, S., Colledge,W. H., Aparicio, S. A., Carlton,M. B., Pearce, J. J., Barton, S. C. et al., Eomesodermin is required for mouse trophoblast development and mesoderm formation. Nature 2000. 404: 95-99.
-
(2000)
Nature
, vol.404
, pp. 95-99
-
-
Russ, A.P.1
Wattler, S.2
Colledge, W.H.3
Aparicio, S.A.4
Carlton, M.B.5
Pearce, J.J.6
Barton, S.C.7
-
21
-
-
0037059462
-
Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells
-
Szabo, S. J., Sullivan, B. M., Stemmann, C., Satoskar, A. R., Sleckman, B. P. and Glimcher, L. H., Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells. Science 2002. 295: 338-342.
-
(2002)
Science
, vol.295
, pp. 338-342
-
-
Szabo, S.J.1
Sullivan, B.M.2
Stemmann, C.3
Satoskar, A.R.4
Sleckman, B.P.5
Glimcher, L.H.6
-
22
-
-
33847153126
-
Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation
-
Jenkinson, S. R., Intlekofer, A. M., Sun, G., Feigenbaum, L., Reiner, S. L. and Bosselut, R., Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation. J. Exp. Med. 2007. 204: 267-272.
-
(2007)
J. Exp. Med
, vol.204
, pp. 267-272
-
-
Jenkinson, S.R.1
Intlekofer, A.M.2
Sun, G.3
Feigenbaum, L.4
Reiner, S.L.5
Bosselut, R.6
-
23
-
-
12144286596
-
In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination
-
Bonifaz, L. C., Bonnyay, D. P., Charalambous, A., Darguste, D. I., Fujii, S., Soares, H., Brimnes, M. K. et al., In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination. J. Exp. Med. 2004. 199: 815-824.
-
(2004)
J. Exp. Med
, vol.199
, pp. 815-824
-
-
Bonifaz, L.C.1
Bonnyay, D.P.2
Charalambous, A.3
Darguste, D.I.4
Fujii, S.5
Soares, H.6
Brimnes, M.K.7
-
24
-
-
0035903328
-
Phenotypic and functional analysis of CD8(+) T cells undergoing peripheral deletion in response to cross-presentation of self-antigen
-
Hernandez, J., Aung, S., Redmond, W. L. and Sherman, L. A., Phenotypic and functional analysis of CD8(+) T cells undergoing peripheral deletion in response to cross-presentation of self-antigen. J. Exp. Med. 2001. 194: 707-717.
-
(2001)
J. Exp. Med
, vol.194
, pp. 707-717
-
-
Hernandez, J.1
Aung, S.2
Redmond, W.L.3
Sherman, L.A.4
-
25
-
-
0032533257
-
Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow
-
Pear, W. S., Miller, J. P., Xu, L., Pui, J. C., Soffer, B., Quackenbush, R. C., Pendergast, A. M. et al., Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow. Blood 1998. 92: 3780-3792.
-
(1998)
Blood
, vol.92
, pp. 3780-3792
-
-
Pear, W.S.1
Miller, J.P.2
Xu, L.3
Pui, J.C.4
Soffer, B.5
Quackenbush, R.C.6
Pendergast, A.M.7
-
26
-
-
0035869583
-
+ TCR-transgenic T cells: Lack of correlation with Src homology domain 2-containing protein tyrosine phosphatase
-
+ TCR-transgenic T cells: Lack of correlation with Src homology domain 2-containing protein tyrosine phosphatase. J. Immunol. 2001. 166: 3900-3907.
-
(2001)
J. Immunol
, vol.166
, pp. 3900-3907
-
-
Gajewski, T.F.1
Fallarino, F.2
Fields, P.E.3
Rivas, F.4
Alegre, M.L.5
-
27
-
-
0031905627
-
Normal responsiveness of CTLA-4-deficient antiviral cytotoxic T cells
-
Bachmann, M. F., Waterhouse, P., Speiser, D. E., McKall-Faienza, K., Mak, T. W. and Ohashi, P. S., Normal responsiveness of CTLA-4-deficient antiviral cytotoxic T cells. J. Immunol. 1998. 160: 95-100.
-
(1998)
J. Immunol
, vol.160
, pp. 95-100
-
-
Bachmann, M.F.1
Waterhouse, P.2
Speiser, D.E.3
McKall-Faienza, K.4
Mak, T.W.5
Ohashi, P.S.6
-
28
-
-
38549089084
-
The reverse stop-signal model for CTLA4 function
-
Rudd, C. E., The reverse stop-signal model for CTLA4 function. Nat. Rev. Immunol. 2008. 8: 153-160.
-
(2008)
Nat. Rev. Immunol
, vol.8
, pp. 153-160
-
-
Rudd, C.E.1
-
29
-
-
33749038866
-
Reversal of the TCR stop signal by CTLA-4
-
Schneider, H., Downey, J., Smith, A., Zinselmeyer, B. H., Rush, C., Brewer, J. M., Wei, B. et al., Reversal of the TCR stop signal by CTLA-4. Science 2006. 313: 1972-1975.
-
(2006)
Science
, vol.313
, pp. 1972-1975
-
-
Schneider, H.1
Downey, J.2
Smith, A.3
Zinselmeyer, B.H.4
Rush, C.5
Brewer, J.M.6
Wei, B.7
-
30
-
-
38349074305
-
CTLA-4 disrupts ZAP70 microcluster formation with reduced T cell/APC dwell times and calcium mobilization
-
Schneider, H., Smith, X., Liu, H., Bismuth, G. and Rudd, C. E., CTLA-4 disrupts ZAP70 microcluster formation with reduced T cell/APC dwell times and calcium mobilization. Eur. J. Immunol. 2008. 38: 40-47.
-
(2008)
Eur. J. Immunol
, vol.38
, pp. 40-47
-
-
Schneider, H.1
Smith, X.2
Liu, H.3
Bismuth, G.4
Rudd, C.E.5
-
32
-
-
33748494020
-
IL-21 inhibits IFN-gamma production in developing Th1 cells through the repression of Eomesodermin expression
-
Suto, A., Wurster, A. L., Reiner, S. L. and Grusby, M. J., IL-21 inhibits IFN-gamma production in developing Th1 cells through the repression of Eomesodermin expression. J. Immunol. 2006. 177: 3721-3727.
-
(2006)
J. Immunol
, vol.177
, pp. 3721-3727
-
-
Suto, A.1
Wurster, A.L.2
Reiner, S.L.3
Grusby, M.J.4
-
34
-
-
34249692621
-
The tyrosine phosphatase SHP-2 regulates differentiation and apoptosis of individual primary T lymphocytes
-
Hoff, H. and Brunner-Weinzierl, M. C., The tyrosine phosphatase SHP-2 regulates differentiation and apoptosis of individual primary T lymphocytes. Eur. J. Immunol. 2007. 37: 1072-1086.
-
(2007)
Eur. J. Immunol
, vol.37
, pp. 1072-1086
-
-
Hoff, H.1
Brunner-Weinzierl, M.C.2
-
35
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
Pfaffl, M. W., A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001. 29: E45.
-
(2001)
Nucleic Acids Res
, vol.29
-
-
Pfaffl, M.W.1
|