Targeted disruption of nonribosomal peptide synthetase Pes3 augments the virulence of Aspergillus fumigatus

Infection and Immunity

Volumn 79, Issue 10, 2011, Pages 3978-3992

  O'Hanlon, Karen A ^a   Cairns, Timothy ^b   Stack, Deirdre ^a   Schrettl, Markus ^a,c   Bignell, Elaine M ^b   Kavanagh, Kevin ^a   Miggin, Sinéad M ^a   O'Keeffe, Grainne ^a   Larsen, Thomas O ^d   Doyle, Sean ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^d TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLUCAN; PEPTIDE SYNTHASE; PEPTIDE SYNTHASE PES 3; UNCLASSIFIED DRUG; VORICONAZOLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIFUNGAL SUSCEPTIBILITY; ARTICLE; ASPERGILLUS FUMIGATUS; CONTROLLED STUDY; FUNGAL SPORE GERMINATION; FUNGAL VIRULENCE; GENE DELETION; GENE DISRUPTION; INNATE IMMUNITY; LUNG ASPERGILLOSIS; MALE; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; ANIMALS, OUTBRED STRAINS; ANTIFUNGAL AGENTS; ASPERGILLUS FUMIGATUS; CELL LINE; FUNGAL PROTEINS; GENE DELETION; MACROPHAGES; MICE; MOTHS; PEPTIDE SYNTHASES; PHENOTYPE; PULMONARY ASPERGILLOSIS; PYRIMIDINES; TRIAZOLES; VIRULENCE;

EID: 80855136630     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00192-11     Document Type: Article

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