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Volumn 36, Issue 13, 2011, Pages 2729-2740

Age, sex, and reproductive hormone effects on brain serotonin-1A and serotonin-2A receptor binding in a healthy population

Author keywords

18F altanserin; 11C WAY100635; age; PET imaging; serotonin receptors; sex

Indexed keywords

ALTANSERIN; ANDROGEN; CARBON 11; ESTRADIOL; FLUORINE 18; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR;

EID: 80855130809     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2011.163     Document Type: Article
Times cited : (67)

References (79)
  • 2
    • 0035669353 scopus 로고    scopus 로고
    • Serotonin 1A receptors, serotonin transporter binding and serotonin transporter mRNA expression in the brainstem of depressed suicide victims
    • DOI 10.1016/S0893-133X(01)00310-4, PII S0893133X01003104
    • Arango V, Underwood MD, Boldrini M, Tamir H, Kassir SA, Hsiung S et al (2001). Serotonin 1A receptors, serotonin transporter binding and serotonin transporter mRNA expression in the brainstem of depressed suicide victims. Neuropsycho-pharmacology 25: 892-903. (Pubitemid 34031894)
    • (2001) Neuropsychopharmacology , vol.25 , Issue.6 , pp. 892-903
    • Arango, V.1    Underwood, M.D.2    Boldrini, M.3    Tamir, H.4    Kassir, S.A.5    Hsiung, S.-C.6    Chen, J.J.-X.7    Mann, J.J.8
  • 3
    • 0029134538 scopus 로고
    • Localized alterations in pre-and postsynaptic serotonin binding sites in the ventrolateral prefrontial cortex of suicide victims
    • Arango V, Underwood MD, Gubbi AV, Mann JJ (1995). Localized alterations in pre-and postsynaptic serotonin binding sites in the ventrolateral prefrontial cortex of suicide victims. Brain Res 688: 121-133.
    • (1995) Brain Res , vol.688 , pp. 121-133
    • Arango, V.1    Underwood, M.D.2    Gubbi, A.V.3    Mann, J.J.4
  • 4
    • 0032869406 scopus 로고    scopus 로고
    • Serotonin neurons, neuroplasticity, and homeostasis of neural tissue
    • Azmitia EC (1999). Serotonin neurons, neuroplasticity, and homeostasis of neural tissue. Neuropsychopharmacology 21: 2S.
    • (1999) Neuropsychopharmacology , vol.21
    • Azmitia, E.C.1
  • 6
    • 0032970989 scopus 로고    scopus 로고
    • A review of central 5-HT receptors and their function
    • DOI 10.1016/S0028-3908(99)00010-6, PII S0028390899000106
    • Barnes NM, Sharp T (1999). A review of central 5-HT receptors and their function. Neuropharmacology 38: 1083-1152. (Pubitemid 29292403)
    • (1999) Neuropharmacology , vol.38 , Issue.8 , pp. 1083-1152
    • Barnes, N.M.1    Sharp, T.2
  • 7
    • 0031962557 scopus 로고    scopus 로고
    • The influence of age and sex on the prevalence of depressive conditions: Report from the National Survey of Psychiatric Morbidity
    • DOI 10.1017/S0033291797006077
    • Bebbington P, Dunn G, Jenkins R, Lewis G, Brugha T, Farrell M et al (1998). The influence of age and sex on the prevalence of depressive conditions: report from the National Survey of Psychiatric Morbidity. Psychol Med 28: 9-19. (Pubitemid 28043564)
    • (1998) Psychological Medicine , vol.28 , Issue.1 , pp. 9-19
    • Bebbington, P.E.1    Dunn, G.2    Jenkins, R.3    Lewis, G.4    Brugha, T.5    Farrell, M.6    Meltzer, H.7
  • 9
    • 0023528585 scopus 로고
    • Modification of 5-HT neuron properties by sustained administration of the 5HT1A agonist gepirone: Electrophysiological studies in the rat brain
    • Blier P, DeMontigny C (1987). Modification of 5-HT neuron properties by sustained administration of the 5HT1A agonist gepirone: electrophysiological studies in the rat brain. Synapse 1: 470-480.
    • (1987) Synapse , vol.1 , pp. 470-480
    • Blier, P.1    Demontigny, C.2
  • 13
    • 0032484518 scopus 로고    scopus 로고
    • Gonadal hormones modulate 5-hydroxytryptamine(2A) receptors: Emphasis on the rat frontal cortex
    • DOI 10.1016/S0306-4522(97)00445-4, PII S0306452297004454
    • Cyr M, Bosse R, Di Paolo T (1998). Gonadal hormones modulate 5-hydroxytryptamine2A receptors: emphasis on the rat frontal cortex. Neuroscience 83: 829-836. (Pubitemid 28068903)
    • (1998) Neuroscience , vol.83 , Issue.3 , pp. 829-836
    • Cyr, M.1    Bosse, R.2    Di Paolo, T.3
  • 18
    • 0034801271 scopus 로고    scopus 로고
    • Expression of serotonin 5-HT(2A) receptors in the human cerebellum and alterations in schizophrenia
    • Eastwood SL, Burnet PW, Gittins R, Baker K, Harrison PJ (2001). Expression of serotonin 5-HT(2A) receptors in the human cerebellum and alterations in schizophrenia. Synapse 42: 104-114.
    • (2001) Synapse , vol.42 , pp. 104-114
    • Eastwood, S.L.1    Burnet, P.W.2    Gittins, R.3    Baker, K.4    Harrison, P.J.5
  • 19
    • 62749107541 scopus 로고    scopus 로고
    • Brain serotonin 2A receptor binding: Relations to body mass index, tobacco and alcohol use
    • Erritzoe D, Frokjaer VG, Haugbol S, Marner L, Svarer C, Holst K et al (2009). Brain serotonin 2A receptor binding: relations to body mass index, tobacco and alcohol use. Neuroimage 46: 23-30.
    • (2009) Neuroimage , vol.46 , pp. 23-30
    • Erritzoe, D.1    Frokjaer, V.G.2    Haugbol, S.3    Marner, L.4    Svarer, C.5    Holst, K.6
  • 22
    • 33750437779 scopus 로고    scopus 로고
    • 1A-mediated autoregulation predicts amygdala reactivity
    • DOI 10.1038/nn1780, PII NN1780
    • Fisher P, Meltzer C, Ziolko S, Price J, Moses-Kolko E, Serga S et al (2006). Capacity for 5-HT1A-mediated autoregulation predicts amygdala reactivity. Nat Neurosci 9: 1362-1363. (Pubitemid 44646205)
    • (2006) Nature Neuroscience , vol.9 , Issue.11 , pp. 1362-1363
    • Fisher, P.M.1    Meltzer, C.C.2    Ziolko, S.K.3    Price, J.C.4    Hariri, A.R.5
  • 23
    • 70349916071 scopus 로고    scopus 로고
    • Medial prefrontal cortex 5-HT2A density is correlated with amygdala reactivity, response habituation, and functional coupling
    • Fisher PM, Meltzer CC, Price JC, Coleman RL, Ziolko SK, Becker C et al (2009). Medial prefrontal cortex 5-HT2A density is correlated with amygdala reactivity, response habituation, and functional coupling. Cereb Cortex 19: 2499-2507.
    • (2009) Cereb Cortex , vol.19 , pp. 2499-2507
    • Fisher, P.M.1    Meltzer, C.C.2    Price, J.C.3    Coleman, R.L.4    Ziolko, S.K.5    Becker, C.6
  • 24
    • 77956617751 scopus 로고    scopus 로고
    • Endogenous plasma estradiol in healthy men is positively correlated with cerebral cortical serotonin 2A receptor binding
    • Frokjaer VG, Erritzoe D, Juul A, Nielsen FA, Holst K, Svarer C et al (2010). Endogenous plasma estradiol in healthy men is positively correlated with cerebral cortical serotonin 2A receptor binding. Psychoneuroendocrinology 35: 1311-1320.
    • (2010) Psychoneuroendocrinology , vol.35 , pp. 1311-1320
    • Frokjaer, V.G.1    Erritzoe, D.2    Juul, A.3    Nielsen, F.A.4    Holst, K.5    Svarer, C.6
  • 25
    • 69249209743 scopus 로고    scopus 로고
    • Gender and the use of hormonal contraception in women are not associated with cerebral cortical 5-HT 2A receptor binding
    • Frokjaer VG, Erritzoe D, Madsen J, Paulson OB, Knudsen GM (2009). Gender and the use of hormonal contraception in women are not associated with cerebral cortical 5-HT 2A receptor binding. Neuroscience 163: 640-645.
    • (2009) Neuroscience , vol.163 , pp. 640-645
    • Frokjaer, V.G.1    Erritzoe, D.2    Madsen, J.3    Paulson, O.B.4    Knudsen, G.M.5
  • 29
    • 80855146207 scopus 로고    scopus 로고
    • Positive relationships between 5HT2A receptor activity in frontal cortical regions after recovery from bulimia nervosa
    • Henry SE, Bailer UF, Frank GK, Meltzer CC, Price JC, Mathis CA et al (2004). Positive relationships between 5HT2A receptor activity in frontal cortical regions after recovery from bulimia nervosa. Biol Psychiatry 55: 105S.
    • (2004) Biol Psychiatry , vol.55
    • Henry, S.E.1    Bailer, U.F.2    Frank, G.K.3    Meltzer, C.C.4    Price, J.C.5    Mathis, C.A.6
  • 31
    • 33750966749 scopus 로고    scopus 로고
    • 1A receptors at different phases of the menstrual cycle in women with premenstrual dysphoria
    • DOI 10.1016/j.pscychresns.2006.05.002, PII S0925492706000904
    • Jovanovic H, Cerin A, Karlsson P, Lundberg J, Halldin C, Nordström AL (2006). A PET study of 5-HT1A receptors at different phases of the menstrual cycle in women with premenstrual dysphoria. Psychiatry Res Neuro 148: 185-193. (Pubitemid 44750584)
    • (2006) Psychiatry Research - Neuroimaging , vol.148 , Issue.2-3 , pp. 185-193
    • Jovanovic, H.1    Cerin, A.2    Karlsson, P.3    Lundberg, J.4    Halldin, C.5    Nordstrom, A.-L.6
  • 32
    • 37849032647 scopus 로고    scopus 로고
    • Sex differences in the serotonin 1A receptor and serotonin transporter binding in the human brain measured by PET
    • Jovanovic H, Lundberg J, Karlsson P, Cerin A, Saijo T, Varrone A et al (2008). Sex differences in the serotonin 1A receptor and serotonin transporter binding in the human brain measured by PET. Neuroimage 39: 1408-1419.
    • (2008) Neuroimage , vol.39 , pp. 1408-1419
    • Jovanovic, H.1    Lundberg, J.2    Karlsson, P.3    Cerin, A.4    Saijo, T.5    Varrone, A.6
  • 33
    • 0027524544 scopus 로고
    • Sex and depression in the National Comorbidity Survey I: Lifetime prevalence, chronicity and recurrence
    • DOI 10.1016/0165-0327(93)90026-G
    • Kessler RC, McGonagle KA, Swartz M, Blazer DG, Nelson CB (1993). Sex and depression in the National Comorbidity Survey I: lifetime prevalence, chronicity and recurrence. J Affect Disord 29: 85-96. (Pubitemid 23334116)
    • (1993) Journal of Affective Disorders , vol.29 , Issue.2-3 , pp. 85-96
    • Kessler, R.C.1    McGonagle, K.A.2    Swartz, M.3    Blazer, D.G.4    Nelson, C.B.5
  • 35
    • 0030468875 scopus 로고    scopus 로고
    • Simplified reference tissue model for PET receptor studies
    • Lammertsma AA, Hume SP (1996). Simplified reference tissue model for PET receptor studies. Neuroimage 4(3 Part 1): 153-158.
    • (1996) Neuroimage , vol.4 , Issue.3 PART 1 , pp. 153-158
    • Lammertsma, A.A.1    Hume, S.P.2
  • 37
    • 0026355999 scopus 로고
    • Fluorine-18-altanserin: A radioligand for the study of serotonin receptors with PET: Radiolabeling and in vivo biologic behavior in rats
    • Lemaire C, Cantineau R, Guillaume M, Plenevaux A, Christiaens L (1991). Fluorine-18-altanserin: a radioligand for the study of serotonin receptors with PET: radiolabeling and in vivo biologic behavior in rats. J Nucl Med 32: 2266-2272.
    • (1991) J Nucl Med , vol.32 , pp. 2266-2272
    • Lemaire, C.1    Cantineau, R.2    Guillaume, M.3    Plenevaux, A.4    Christiaens, L.5
  • 39
    • 0032821347 scopus 로고    scopus 로고
    • Role of the serotonergic system in the pathogenesis of major depression and suicidal behavior
    • DOI 10.1016/S0893-133X(99)00040-8, PII S0893133X99000408
    • Mann JJ (1999). Role of the serotonergic system in the pathogen-esis of major depression and suicidal behavior. Neuropsycho-pharmacology 21(2 Suppl): 99S-105S. (Pubitemid 29396477)
    • (1999) Neuropsychopharmacology , vol.21 , Issue.SUPPL.2
    • Mann, J.J.1
  • 40
    • 0025914512 scopus 로고
    • Serotonergic measures in suicide brain: 5-HT1A binding sites in frontal cortex of suicide victims
    • Matsubara S, Arora RC, Meltzer HY (1991). Serotonergic measures in suicide brain: 5-HT1A binding sites in frontal cortex of suicide victims. J Neural Transm Gen Sect 85: 181-194.
    • (1991) J Neural Transm Gen Sect , vol.85 , pp. 181-194
    • Matsubara, S.1    Arora, R.C.2    Meltzer, H.Y.3
  • 41
    • 0029798822 scopus 로고    scopus 로고
    • 11C-carboxylation of an immobilized Grignard reagent
    • DOI 10.1002/(SICI)1099-1344(199610)38:10<941::AID-JLCR906>3.0.CO;2- Y
    • McCarron JA, Turton D, Pike VW, Poole K (1996). Remotely controlled production of the 5HT1A receptor radioligand, [carbonyl-11C]WAY-100635, via 11C-carboxylation of an immobilized Grignard reagent. J Labelled Comp Radiopharm 38: 941-953. (Pubitemid 26338669)
    • (1996) Journal of Labelled Compounds and Radiopharmaceuticals , vol.38 , Issue.10 , pp. 941-953
    • McCarron, J.A.1    Turton, D.R.2    Pike, V.W.3    Poole, K.G.4
  • 47
    • 44249125480 scopus 로고    scopus 로고
    • Applying neuroimaging ligands to study major depressive disorder
    • DOI 10.1053/j.semnuclmed.2008.02.007, PII S0001299808000305
    • Meyer JH (2008). Applying neuroimaging ligands to study major depressive disorder. Semin Nucl Med 38: 287-304. (Pubitemid 351726327)
    • (2008) Seminars in Nuclear Medicine , vol.38 , Issue.4 , pp. 287-304
    • Meyer, J.H.1
  • 49
    • 0034667339 scopus 로고    scopus 로고
    • Effects of estradiol and progesterone administration on human serotonin 2A receptor binding: A PET study
    • Moses EL, Drevets WC, Smith G, Mathis CA, Kalro BN, Butters MA et al (2000). Effects of estradiol and progesterone administration on human serotonin 2A receptor binding: a PET study. Biol Psychiatry 48: 854-860.
    • (2000) Biol Psychiatry , vol.48 , pp. 854-860
    • Moses, E.L.1    Drevets, W.C.2    Smith, G.3    Mathis, C.A.4    Kalro, B.N.5    Butters, M.A.6
  • 50
    • 85047676639 scopus 로고    scopus 로고
    • Effects of chronic 17beta-estradiol treatment on the serotonin 5-HT(1A) receptor mRNA and binding levels in the rat brain
    • Osterlund MK, Halldin C, Hurd YL (2000). Effects of chronic 17beta-estradiol treatment on the serotonin 5-HT(1A) receptor mRNA and binding levels in the rat brain. Synapse 35: 39-44.
    • (2000) Synapse , vol.35 , pp. 39-44
    • Osterlund, M.K.1    Halldin, C.2    Hurd, Y.L.3
  • 51
    • 0032579761 scopus 로고    scopus 로고
    • Acute 17β-estradiol treatment down-regulates serotonin 5HT(1A) receptor mRNA expression in the limbic system of female rats
    • DOI 10.1016/S0169-328X(98)00018-7, PII S0169328X98000187
    • Osterlund MK, Hurd YL (1998). Acute 17 beta-estradiol treatment down-regulates serotonin 5HT1A receptor mRNA expression in the limbic system of female rats. Brain Res Mol Brain Res 55: 169-172. (Pubitemid 28236602)
    • (1998) Molecular Brain Research , vol.55 , Issue.1 , pp. 169-172
    • Osterlund, M.K.1    Hurd, Y.L.2
  • 52
    • 0030742954 scopus 로고    scopus 로고
    • Apparent absence of aging and gender effects on serotonin 1A receptors in human neocortex and hippocampus
    • DOI 10.1016/S0006-8993(96)01415-1, PII S0006899396014151
    • Palego L, Marazziti D, Rossi A, Giannaccini G, Naccarato AG, Lucacchini A et al (1997). Apparent absence of aging and gender effects on serotonin 1A receptors in human neocortex and hippocampus. Brain Res 758: 26-32. (Pubitemid 27310638)
    • (1997) Brain Research , vol.758 , Issue.1-2 , pp. 26-32
    • Palego, L.1    Marazziti, D.2    Rossi, A.3    Giannaccini, G.4    Naccarato, A.G.5    Lucacchini, A.6    Cassano, G.B.7
  • 55
    • 0037044881 scopus 로고    scopus 로고
    • 1A receptor binding potential measured by PET using [C-11]WAY-100635
    • DOI 10.1016/S0006-8993(02)03243-2, PII S0006899302032432
    • Parsey RV, Oquendo MA, Simpson NR, Ogden RT, Van Heertum R, Arango V et al (2002). Effects of sex, age, and aggressive traits in man on brain serotonin 5-HT1A receptor binding potential measured by PET using [C-11]WAY-100635. Brain Res 954: 173-182. (Pubitemid 35284657)
    • (2002) Brain Research , vol.954 , Issue.2 , pp. 173-182
    • Parsey, R.V.1    Oquendo, M.A.2    Simpson, N.R.3    Ogden R.Todd4    Van Heertum, R.5    Arango, V.6    Mann J.John7
  • 57
    • 0033105944 scopus 로고    scopus 로고
    • Ovarian steroid regulation of serotonin-1A autoreceptor messenger RNA expression in the dorsal raphe of rhesus macaques
    • DOI 10.1016/S0306-4522(98)00326-1, PII S0306452298003261
    • Pecins-Thompson M, Bethea CL (1999). Ovarian steroid regulation of serotonin-1A autoreceptor messenger RNA expression in the dorsal raphe of rhesus macaques. Neuroscience 89: 267-277. (Pubitemid 29049044)
    • (1999) Neuroscience , vol.89 , Issue.1 , pp. 267-277
    • Pecins-Thompson, M.1    Bethea, C.L.2
  • 58
  • 59
    • 33645618903 scopus 로고    scopus 로고
    • Impact of graphical analysis bias on group comparisons of regional [carbonyl-11C]WAY binding potential measures
    • Price JC, Xu L, Mazumdar S, Meltzer CC, Drevets WC, Mathis CA et al (2002a). Impact of graphical analysis bias on group comparisons of regional [carbonyl-11C]WAY binding potential measures. Neuroimage 16: S72.
    • (2002) Neuroimage , vol.16
    • Price, J.C.1    Xu, L.2    Mazumdar, S.3    Meltzer, C.C.4    Drevets, W.C.5    Mathis, C.A.6
  • 60
    • 0036338529 scopus 로고    scopus 로고
    • 1A receptors in normal male volunteers: Normative data and relationship to methodological, demographic, physiological, and behavioral variables
    • DOI 10.1006/nimg.2001.0984
    • Rabiner EA, Messa C, Sargent PA, Husted-Kjaer K, Montgomery A, Lawrence AD et al (2002). A database of [(11)C]WAY-100635 binding to 5-HT(1A) receptors in normal male volunteers: normative data and relationship to methodological, demographic, physiological, and behavioral variables. Neuroimage 15: 620-632. (Pubitemid 34852530)
    • (2002) NeuroImage , vol.15 , Issue.3 , pp. 620-632
    • Rabiner, E.A.1    Messa, C.2    Sargent, P.A.3    Husted-Kjaer, K.4    Montgomery, A.5    Lawrence, A.D.6    Bench, C.J.7    Gunn, R.N.8    Cowen, P.9    Grasby, P.M.10
  • 62
    • 33751165247 scopus 로고    scopus 로고
    • Serotonin-1A receptor activity and expression modulate adolescent anabolic/androgenic steroid-induced aggression in hamsters
    • DOI 10.1016/j.pbb.2006.06.022, PII S0091305706002061
    • Ricci LA, Rasakham K, Grimes JM, Melloni JRH (2006). Serotonin-1A receptor activity and expression modulate adolescent anabolic/androgenic steroid-induced aggression in hamsters. Pharmacol Biochem Behav 85: 1-11. (Pubitemid 44773721)
    • (2006) Pharmacology Biochemistry and Behavior , vol.85 , Issue.1 , pp. 1-11
    • Ricci, L.A.1    Rasakham, K.2    Grimes, J.M.3    Melloni Jr., R.H.4
  • 66
    • 36448980625 scopus 로고    scopus 로고
    • Important messages in the 'post': Recent discoveries in 5-HT neurone feedback control
    • DOI 10.1016/j.tips.2007.10.009, PII S0165614707002519
    • Sharp T, Boothman L, Raley J, Queree P (2007). Important messages in the 'post': recent discoveries in 5-HT neurone feedback control. Trends Pharmacol Sci 28: 629-636. (Pubitemid 350166575)
    • (2007) Trends in Pharmacological Sciences , vol.28 , Issue.12 , pp. 629-636
    • Sharp, T.1    Boothman, L.2    Raley, J.3    Queree, P.4
  • 68
    • 0032441591 scopus 로고    scopus 로고
    • Testosterone and its metabolites modulate 5HT(1A) and 5HT(1B) agonist effects on intermale aggression
    • DOI 10.1016/S0149-7634(98)00034-7, PII S0149763498000347
    • Simon NG, Cologer-Clifford A, Lu S-f, McKenna SE, Hu S (1998). Testosterone and its metabolites modulate 5HT1A and 5HT1B agonist effects on intermale aggression. Neurosci Biobehav Rev 23: 325-336. (Pubitemid 29011635)
    • (1998) Neuroscience and Biobehavioral Reviews , vol.23 , Issue.2 , pp. 325-336
    • Simon, N.G.1    Cologer-Clifford, A.2    Lu, S.-F.3    McKenna, S.E.4    Hu, S.5
  • 70
  • 72
    • 58149310787 scopus 로고    scopus 로고
    • The serotonin-1A receptor distribution in healthy men and women measured by PET and [carbonyl-11C]WAY-100635 (see comment)
    • Stein P, Savli M, Wadsak W, Mitterhauser M, Fink M, Spindelegger C et al (2008). The serotonin-1A receptor distribution in healthy men and women measured by PET and [carbonyl-11C]WAY-100635 (see comment). Eur J Nucl Med Mol Imaging 35: 2159-2168.
    • (2008) Eur J Nucl Med Mol Imaging , vol.35 , pp. 2159-2168
    • Stein, P.1    Savli, M.2    Wadsak, W.3    Mitterhauser, M.4    Fink, M.5    Spindelegger, C.6
  • 73
    • 0032530289 scopus 로고    scopus 로고
    • Increase in serotonin-1A autoreceptors in the midbrain of suicide victims with major depression-postmortem evidence for decreased serotonin activity
    • Stockmeier CA, Shapiro LA, Dilley GE, Kolli TN, Friedman L, Rajkowska G (1998). Increase in serotonin-1A autoreceptors in the midbrain of suicide victims with major depression-postmortem evidence for decreased serotonin activity. J Neurosci 18: 7394-7401.
    • (1998) J Neurosci , vol.18 , pp. 7394-7401
    • Stockmeier, C.A.1    Shapiro, L.A.2    Dilley, G.E.3    Kolli, T.N.4    Friedman, L.5    Rajkowska, G.6
  • 74
    • 0029082499 scopus 로고
    • Estrogen increases the density of 5-HT2A receptors in cerebral cortex and nucleus accumbens in the female rat
    • Sumner BE, Fink G (1995). Estrogen increases the density of 5-HT2A receptors in cerebral cortex and nucleus accumbens in the female rat. J Steroid Biochem Mol Biol 54(1/2): 15-20.
    • (1995) J Steroid Biochem Mol Biol , vol.54 , Issue.1-2 , pp. 15-20
    • Sumner, B.E.1    Fink, G.2
  • 75
    • 0032584945 scopus 로고    scopus 로고
    • Testosterone as well as estrogen increases serotonin(2A) receptor mRNA and binding site densities in the male rat brain
    • DOI 10.1016/S0169-328X(98)00148-X, PII S0169328X9800148X
    • Sumner BE, Fink G (1998). Testosterone as well as estrogen increases serotonin2A receptor mRNA and binding site densities in the male rat brain. Brain Res Mol Brain Res 59: 205-214. (Pubitemid 28434503)
    • (1998) Molecular Brain Research , vol.59 , Issue.2 , pp. 205-214
    • Sumner, B.E.H.1    Fink, G.2
  • 79
    • 0032836673 scopus 로고    scopus 로고
    • Sex differences in expression of serotonin receptors (subtypes 1A and 2A) in rat brain: A possible role of testosterone
    • DOI 10.1016/S0306-4522(99)00234-1, PII S0306452299002341
    • Zhang L, Ma W, Barker JL, Rubinow DR (1999). Sex differences in expression of serotonin receptors (subtypes 1A and 2A) in rat brain: a possible role of testosterone. Neuroscience 94: 251-259. (Pubitemid 29457615)
    • (1999) Neuroscience , vol.94 , Issue.1 , pp. 251-259
    • Zhang, L.1    Ma, W.2    Barker, J.L.3    Rubinow, D.R.4


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