Serotonin 5-HT1A receptor binding potential declines with age as measured by [11C]WAY-100635 and PET

Neuropsychopharmacology

Volumn 24, Issue 5, 2001, Pages 522-530

  Tauscher, Johannes ^a,c   Verhoeff, N PaulL G ^a,b   Christensen, Bruce K ^a,b   Hussey, Doug ^a   Meyer, Jeffrey H ^a,b   Kecojevic, Alex ^a   Javanmard, Mahan ^a   Kasper, Siegfried ^a,b,c   Kapur, Shitij ^a,b,c  

^a CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF VIENNA   (Austria)

Author keywords

5 HT1A receptors; 11C WAY 100635; Age effects; Positron emission tomography

Indexed keywords

N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SEROTONIN 1A RECEPTOR; CARBON; PIPERAZINE DERIVATIVE; PYRIDINE DERIVATIVE; SEROTONIN; SEROTONIN 1 RECEPTOR; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

ADULT; AGE; ANALYTIC METHOD; ARTICLE; BRAIN REGION; CONTROLLED STUDY; FEMALE; HUMAN; ISOTOPE LABELING; MALE; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RECEPTOR BINDING; REPRODUCIBILITY; AGING; BINDING SITE; BRAIN; BRAIN CORTEX; BRAIN MAPPING; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DRUG EFFECT; IMAGE PROCESSING; METABOLISM; MIDDLE AGED; NERVE CELL; PHYSIOLOGY; RAPHE NUCLEUS;

ADULT; AGING; BINDING SITES; BRAIN; BRAIN MAPPING; CARBON RADIOISOTOPES; CEREBRAL CORTEX; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; MIDDLE AGED; NEURONS; PIPERAZINES; PYRIDINES; RAPHE NUCLEI; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN; SEROTONIN ANTAGONISTS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0034745162     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(00)00227-X     Document Type: Article

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