Next-generation sequencing of apoptotic DNA breakpoints reveals association with actively transcribed genes and gene translocations

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Fullwood, Melissa J ^a,b,c   Lee, Joanne ^b   Lin, Lifang ^a   Li, Guoliang ^b   Huss, Mikael ^d   Ng, Patrick ^d   Sung, Wing Kin ^b   Shenolikar, Shirish ^a,e  

^a DUKE NUS MEDICAL SCHOOL   (Singapore)

^b GENOME INSTITUTE OF SINGAPORE   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d 1stBASE Pte Ltd   (Singapore)

^e DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DACTINOMYCIN; DNA; GENOMIC DNA; MICRORNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR;

APOPTOSIS; ARTICLE; BINDING SITE; CHROMATIN; CONTROLLED STUDY; DNA CLEAVAGE; DNA FRAGMENTATION; DNA SEQUENCE; DNA STRAND BREAKAGE; GENE EXPRESSION; GENE SEQUENCE; GENE TRANSLOCATION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN CELL; LEUKEMIA CELL; POLYMERASE CHAIN REACTION; GENETICS; METHODOLOGY; NUCLEOTIDE SEQUENCE; TUMOR CELL LINE;

APOPTOSIS; BASE SEQUENCE; BINDING SITES; CELL LINE, TUMOR; DACTINOMYCIN; DNA FRAGMENTATION; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSLOCATION, GENETIC;

EID: 80655129374     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026054     Document Type: Article

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