Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway

Journal of Experimental Medicine

Volumn 208, Issue 10, 2011, Pages 1963-1976

  Viatour, Patrick ^a,d,f   Ehmer, Ursula ^a   Saddic, Louis A ^a   Dorrell, Craig ^c   Andersen, Jesper B ^e   Lin, Chenwei ^a   Zmoos, Anne Flore ^a   Mazur, Pawel K ^a   Schaffer, Bethany E ^a   Ostermeier, Austin ^a   Vogel, Hannes ^b   Sylvester, Karl G ^a   Thorgeirsson, Snorri S ^e   Grompe, Markus ^c   Sage, Julien ^a  

^a STANFORD UNIVERSITY   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d UNIVERSITY OF LIÈGE   (Belgium)

^e NATIONAL CANCER INSTITUTE   (United States)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH3 RECEPTOR; NOTCH4 RECEPTOR; PROTEIN P16; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR E2F3; TRANSCRIPTION FACTOR E2F4; TRANSCRIPTION FACTOR HES 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER MODEL; CANCER PATIENT; CANCER STEM CELL; CANCER SURVIVAL; CELL EXPANSION; CONTROLLED STUDY; EPIGENETICS; GENE; GENE DELETION; GENE EXPRESSION PROFILING; HISTOPATHOLOGY; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; LIVER CELL CARCINOMA; MOUSE; MULTIGENE FAMILY; NEGATIVE FEEDBACK; NONHUMAN; P107 GENE; P130 GENE; PRIORITY JOURNAL; RB GENE; SIGNAL TRANSDUCTION; TUMOR GROWTH;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL LINE; CELL PROLIFERATION; E2F TRANSCRIPTION FACTORS; GENE EXPRESSION PROFILING; HUMANS; LIVER NEOPLASMS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROARRAY ANALYSIS; RECEPTORS, NOTCH; RETINOBLASTOMA PROTEIN; SIGNAL TRANSDUCTION; STEM CELLS; TRANSCRIPTION, GENETIC;

EID: 80555154065     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20110198     Document Type: Article

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