N,N-Bis(cyclohexanol)amine aryl esters inhibit P-glycoprotein as transport substrates

Biochemical Pharmacology

Volumn 82, Issue 12, 2011, Pages 1822-1831

  Neri, Annalisa ^a,b   Frosini, Maria ^a,b   Valoti, Massimo ^a,b   Cacace, Marcello G ^a   Teodori, Elisabetta ^c   Sgaragli, Giampietro ^a,b  

^a UNIVERSITY OF SIENA   (Italy)

^b ISTITUTO TOSCANO TUMORI   (Italy)

^c UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Epirubicin; MDR reverters; Mouse T lymphoma MDR1 cells; N,N Bis(cyclohexanol)amine aryl esters; Pgp inhibitors; Rhodamine123 cell efflux; Sf 9 ATPase activity

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CYCLOSPORIN A; ELACRIDAR; EPIRUBICIN; GLYCOPROTEIN P; GLYCOPROTEIN P INHIBITOR; MULTIDRUG RESISTANCE PROTEIN 1; N,N BIS(CYCLOHEXANOL)AMINE ARYL ESTER DERIVATIVE; RHODAMINE 123; UNCLASSIFIED DRUG;

ANIMAL CELL; BINDING SITE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG POTENCY; ENZYME ACTIVATION; ENZYME ACTIVITY; IC 50; IN VITRO STUDY; LYMPHOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATASES; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL MEMBRANE; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION; HUMANS; MICE; P-GLYCOPROTEIN;

EID: 80555122929     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.08.025     Document Type: Conference Paper

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