Context mediates antimicrobial efficacy of kinocidin congener peptide RP-1

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Yount, Nannette Y ^a   Cohen, Samuel E ^a,b   Kupferwasser, Deborah ^a   Waring, Alan J ^a,b,c   Ruchala, Piotr ^c   Sharma, Shantanu ^d   Wasserman, Karlman ^a   Jung, Chun Ling ^c   Yeaman, Michael R ^a,c  

^a HARBOR UCLA MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLYPEPTIDE ANTIBIOTIC AGENT; RP 1 PEPTIDE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; RP-1 PEPTIDE;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; CANDIDA ALBICANS; CONTROLLED STUDY; DRUG BINDING; DRUG EFFICACY; DRUG SPECIFICITY; FUNGAL STRAIN; INFRARED SPECTROSCOPY; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; PH; PHYSICAL CHEMISTRY; SALMONELLA TYPHIMURIUM; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION; SURFACE PLASMON RESONANCE; CHEMISTRY; DRUG EFFECT; KINETICS; MICROBIOLOGICAL EXAMINATION; NUCLEAR MAGNETIC RESONANCE;

BACTERIA (MICROORGANISMS); CANDIDA ALBICANS; EUKARYOTA; SALMONELLA TYPHIMURIUM; STAPHYLOCOCCUS AUREUS;

ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; CANDIDA ALBICANS; HYDROGEN-ION CONCENTRATION; KINETICS; MICROBIAL SENSITIVITY TESTS; MOLECULAR DYNAMICS SIMULATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; SALMONELLA TYPHIMURIUM; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STAPHYLOCOCCUS AUREUS;

EID: 80455145124     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026727     Document Type: Article

References (52)

1. Yount NY, Yeaman MR, (2004) Multidimensional signatures in antimicrobial peptides. Proc Natl Acad Sci U S A 101: 7363-7368.
2. Yeaman MR, Yount NY, (2003) Mechanisms of antimicrobial peptide action and resistance. Pharmacol Rev 55: 27-55.
3. Hancock RE, (1997) Peptide antibiotics. Lancet 349: 418-422.
4. Guyton AC, (2005) Textbook of Medical Physiology W. B. Saunders Company.
5. Waugh A, Grant A, (2007) Anatomy and Physiology in health and Illness Churchill Livingstone Elsevier.
6. Yeaman MR, Yount N, (2005) Code among chaos:immunorelativity and the AEGIS model of antimicrobial peptides. Microbe 71: 21-27.
7. Yeaman MR, Yount NY, (2007) Unifying themes in host defence effector polypeptides. Nat Rev Microbiol 5: 727-740.
8. Yount NY, Kupferwasser D, Spisni A, Dutz SM, Ramjan ZH, et al. (2009) Selective reciprocity in antimicrobial activity versus cytotoxicity of hBD-2 and crotamine. Proc Natl Acad Sci U S A 106: 14972-14977.
9. Bayer AS, McNamara P, Yeaman MR, Lucindo N, Jones T, et al. (2006) Transposon disruption of the complex I NADH oxidoreductase gene (snoD) in Staphylococcus aureus is associated with reduced susceptibility to the microbicidal activity of thrombin-induced platelet microbicidal protein 1. J Bacteriol 188: 211-222.
10. Bourbigot S, Dodd E, Horwood C, Cumby N, Fardy L, et al. (2009) Antimicrobial peptide RP-1 structure and interactions with anionic versus zwitterionic micelles. Biopolymers 91: 1-13.
11. Mani R, Cady SD, Tang M, Waring AJ, Lehrer RI, et al. (2006) Membrane-dependent oligomeric structure and pore formation of a beta-hairpin antimicrobial peptide in lipid bilayers from solid-state NMR. Proc Natl Acad Sci U S A 103: 16242-16247.
12. Yeaman MR, Gank KD, Bayer AS, Brass EP, (2002) Synthetic peptides that exert antimicrobial activities in whole blood and blood-derived matrices. Antimicrob Agents Chemother 46: 3883-3891.
13. Yeaman MR, Kupferwasser D, Yount NY, Waring AJ, Ruchala P, et al. (2009) Efficacy of intravenous platelet kinocidin congener RP-1 in a murine model of Staphylococcus aureus (SA) biofilm infection.; San Francisco, CA.
14. Fields PI, Groisman EA, Heffron F, (1989) A Salmonella locus that controls resistance to microbicidal proteins from phagocytic cells. Science 243: 1059-1062.
15. Marx F, Binder U, Leiter E, Pocsi I, (2008) The Penicillium chrysogenum antifungal protein PAF, a promising tool for the development of new antifungal therapies and fungal cell biology studies. Cell Mol Life Sci 65: 445-454.
16. Thevissen K, Ghazi A, De Samblanx GW, Brownlee C, Osborn RW, et al. (1996) Fungal membrane responses induced by plant defensins and thionins. J Biol Chem 271: 15018-15025.
17. Xiong YQ, Bayer AS, Elazegui L, Yeaman MR, (2006) A synthetic congener modeled on a microbicidal domain of thrombin- induced platelet microbicidal protein 1 recapitulates staphylocidal mechanisms of the native molecule. Antimicrob Agents Chemother 50: 3786-3792.
18. Fu Y, Gank K, Kupferwasser D, Yount N, Park H, et al. SSD1 is integral to antimicrobial peptide resistance in Candida albicans.; 2005; Atlanta Georgia.
19. Zurgil N, Schiffer Z, Shafran Y, Kaufman M, Deutsch M, (2000) Fluorescein fluorescence hyperpolarization as an early kinetic measure of the apoptotic process. Biochem Biophys Res Commun 268: 155-163.
20. Helmerhorst EJ, Troxler RF, Oppenheim FG, (2001) The human salivary peptide histatin 5 exerts its antifungal activity through the formation of reactive oxygen species. Proc Natl Acad Sci U S A 98: 14637-14642.
21. Gyurko C, Lendenmann U, Helmerhorst EJ, Troxler RF, Oppenheim FG, (2001) Killing of Candida albicans by histatin 5: cellular uptake and energy requirement. Antonie Van Leeuwenhoek 79: 297-309.
22. Jang WS, Bajwa JS, Sun JN, Edgerton M, (2010) Salivary histatin 5 internalization by translocation, but not endocytosis, is required for fungicidal activity in Candida albicans. Mol Microbiol 77: 354-370.
23. Hale JD, Hancock RE, (2007) Alternative mechanisms of action of cationic antimicrobial peptides on bacteria. Expert Rev Anti Infect Ther 5: 951-959.
24. Yeaman MR, Bayer AS, Koo SP, Foss W, Sullam PM, (1998) Platelet microbicidal proteins and neutrophil defensin disrupt the Staphylococcus aureus cytoplasmic membrane by distinct mechanisms of action. J Clin Invest 101: 178-187.
25. Yount NY, Waring AJ, Gank KD, Welch WH, Kupferwasser D, et al. (2007) Structural correlates of antimicrobial efficacy in IL-8 and related human kinocidins. Biochim Biophys Acta 1768: 598-608.
26. Shai Y, Oren Z, (2001) From "carpet" mechanism to de-novo designed diastereomeric cell-selective antimicrobial peptides. Peptides 22: 1629-1641.
27. Pag U, Oedenkoven M, Sass V, Shai Y, Shamova O, et al. (2008) Analysis of in vitro activities and modes of action of synthetic antimicrobial peptides derived from an alpha-helical 'sequence template'. J Antimicrob Chemother 61: 341-352.
28. Katzif S, Danavall D, Bowers S, Balthazar JT, Shafer WM, (2003) The major cold shock gene, cspA, is involved in the susceptibility of Staphylococcus aureus to an antimicrobial peptide of human cathepsin G. Infect Immun 71: 4304-4312.
29. Herrero E, Ros J, Belli G, Cabiscol E, (2008) Redox control and oxidative stress in yeast cells. Biochim Biophys Acta 1780: 1217-1235.
30. Yeaman MR, Cheng D, Desai B, Kupferwasser LI, Xiong YQ, et al. (2004) Susceptibility to thrombin-induced platelet microbicidal protein is associated with increased fluconazole efficacy against experimental endocarditis due to Candida albicans. Antimicrob Agents Chemother 48: 3051-3056.
31. Yount NY, Gank KD, Xiong YQ, Bayer AS, Pender T, et al. (2004) Platelet microbicidal protein 1: structural themes of a multifunctional antimicrobial peptide. Antimicrob Agents Chemother 48: 4395-4404.
32. Yeaman MR, Yount NY, Waring AJ, Gank KD, Kupferwasser D, et al. (2007) Modular determinants of antimicrobial activity in platelet factor-4 family kinocidins. Biochim Biophys Acta 1768: 609-619.
33. Zidovetzki R, Rost B, Armstrong DL, Pecht I, (2003) Transmembrane domains in the functions of Fc receptors. Biophys Chem 100: 555-575.
34. Tang YQ, Yeaman MR, Selsted ME, (2002) Antimicrobial peptides from human platelets. Infect Immun 70: 6524-6533.
35. Baxter DF, Kirk M, Garcia AF, Raimondi A, Holmqvist MH, et al. (2002) A novel membrane potential-sensitive fluorescent dye improves cell-based assays for ion channels. J Biomol Screen 7: 79-85.
36. Dorn A, Hermann F, Ebneth A, Bothmann H, Trube G, et al. (2005) Evaluation of a high-throughput fluorescence assay method for HERG potassium channel inhibition. J Biomol Screen 10: 339-347.
37. Slack M, Kirchhoff C, Moller C, Winkler D, Netzer R, (2006) Identification of novel Kv1.3 blockers using a fluorescent cell-based ion channel assay. J Biomol Screen 11: 57-64.
38. Pace CN, Vajdos F, Fee L, Grimsley G, Gray T, (1995) How to measure and predict the molar absorption coefficient of a protein. Protein Sci 4: 2411-2423.
39. White SH, Wimley WC, (1999) Membrane protein folding and stability: physical principles. Annu Rev Biophys Biomol Struct 28: 319-365.
40. Yamaguchi S, Hong T, Waring A, Lehrer RI, Hong M, (2002) Solid-state NMR investigations of peptide-lipid interaction and orientation of a beta-sheet antimicrobial peptide, protegrin. Biochemistry 41: 9852-9862.
41. Kauppinen JMD, Mantsch H, Cameron D, (1981) Fourier self-deconvolution: A method for resolving intrinsically overlapped bands. Applied Spectroscopy 35: 272-278.
42. Byler DM, Susi H, (1986) Examination of the secondary structure of proteins by deconvolved FTIR spectra. Biopolymers 25: 469-487.
43. Gordon LM, Horvath S, Longo ML, Zasadzinski JA, Taeusch HW, et al. (1996) Conformation and molecular topography of the N-terminal segment of surfactant protein B in structure-promoting environments. Protein Sci 5: 1662-1675.
44. Harrick NJ, (1967) Internal Reflection Spectroscopy New York Interscience.
45. Hess M, Kutzner C, Van der Spoel D, Lindahl E, (2008) GROMACS 4: Algorithms for highly efficent, load-balanced, and scalable molecular simulation. J Chem Theory Comput 4.
46. Poger D, Mark AE, (2010) On the validation of molecular dynamics simulations of saturated and cis-monounsaturated phosphatidylcholine lipid bilayers: a comparison with experiment. Journal of Chemical Theory and Computation 6: 325-336.
47. Kukol A, (2009) Lipid models for united-atom molecular dynamics simulations of proteins. Journal of Chemical Theory and Computation 5: 615-626.
48. Lipp MM, Lee KY, Zasadzinski JA, Waring AJ, (1996) Phase and morphology changes in lipid monolayers induced by SP-B protein and its amino-terminal peptide. Science 273: 1196-1199.
49. Lipp MM, Lee KYC, Takamoto DY, Zasadzinski JAN, Waring AJ, (1998) Coexistence of buckled and flat monolayers. Physical Rev Lett 81: 1650-1653.
50. Elmore DE, Guayasamin RC, Kieffer ME, (2010) A series of molecular dynamics and homology modeling computer labs for an undergraduate molecular modeling course. Biochem Mol Biol Educ 38: 216-223.
51. Gautier R, Camproux AC, Tuffery P, (2004) SCit: web tools for protein side chain conformation analysis. Nucleic Acids Res 32: W508-511.
52. Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, et al. (2004) UCSF Chimera-a visualization system for exploratory research and analysis. J Comput Chem 25: 1605-1612.