From "carpet" mechanism to de-novo designed diastereomeric cell-selective antimicrobial peptides

Peptides

Volumn 22, Issue 10, 2001, Pages 1629-1641

  Shai, Yechiel ^a   Oren, Ziv ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Antibacterial peptides; Diastereomers; Innate immunity; Lysis; Lytic peptide

Indexed keywords

AMINO ACID; BACTERIUM LIPOPOLYSACCHARIDE; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CECROPIN; CYCLIC LYSYLLYSYLLYSYLLYSYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLLEUCYLTRYPTOPHAN; DERMASEPTIN; DEXTRO AMINO ACID; MELITTIN; PARDAXIN; POLYPEPTIDE ANTIBIOTIC AGENT; TETRACYCLINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL MEMBRANE; CELL SPECIFICITY; CHANNEL GATING; CYCLIZATION; CYTOTOXICITY; DIASTEREOISOMER; DRUG BINDING; DRUG MECHANISM; DRUG SELECTIVITY; IMMUNITY; MEMBRANE DAMAGE; MEMBRANE TRANSPORT; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OLIGOMERIZATION; PHOSPHOLIPID MEMBRANE; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; SPECIES DIFFERENCE; STRUCTURE ACTIVITY RELATION;

BACTERIA (MICROORGANISMS);

EID: 0034824597     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(01)00498-3     Document Type: Review

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