Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription

FASEB Journal

Volumn 25, Issue 11, 2011, Pages 3884-3895

  Alejandro, Emilyn U ^a   Lim, Gareth E ^a   Mehran, Arya E ^a   Hu, Xiaoke ^a   Taghizadeh, Farnaz ^a   Pelipeychenko, Dmytro ^a   Baccarini, Manuela ^b   Johnson, James D ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

Diabetes; Growth factor signaling; Knockout mouse models

Indexed keywords

ACTIN; B RAF KINASE; BETA ACTIN; BETA TUBULIN; CRE RECOMBINASE; GLUCOSE; INSULIN; INSULIN RECEPTOR; LAMIN A; LAMIN C; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BAD; RAF PROTEIN; SOMATOMEDIN C RECEPTOR; SYNAPTOBREVIN 2; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; SYNTAXIN 1; SYNTAXIN 4; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR PDX 1;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CELL PROTECTION; CELL SURVIVAL; CELL TYPE; CONTROLLED STUDY; DIET RESTRICTION; EXOCYTOSIS; FEMALE; GENE; GENETIC TRANSCRIPTION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; HORMONAL REGULATION; HUMAN; HUMAN CELL; IMPAIRED GLUCOSE TOLERANCE; IN VITRO STUDY; IN VIVO STUDY; INSULIN 2 GENE; INSULIN RELEASE; INSULIN TOLERANCE TEST; KNOCKOUT MOUSE; LOXP SITE; MOUSE; NONHUMAN; PANCREAS FUNCTION; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BLOOD GLUCOSE; CELL PROLIFERATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HOMEOSTASIS; INSULIN; INSULIN-SECRETING CELLS; MALE; MICE; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS C-RAF;

MUS;

EID: 80355131357     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-180349     Document Type: Article

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