-
1
-
-
0030465237
-
HMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6
-
DOI 10.1073/pnas.93.24.13629
-
S. Acharya, T. Wilson, S. Gradia, M.F. Kane, S. Guerrette, and G.T. Marsischky hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6 Proc Natl Acad Sci USA 93 1996 13629 13634 (Pubitemid 26424170)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.24
, pp. 13629-13634
-
-
Acharya, S.1
Wilson, T.2
Gradia, S.3
Kane, M.F.4
Guerrette, S.5
Marsischky, G.T.6
Kolodner, R.7
Fishel, R.8
-
2
-
-
0032508504
-
Enhanced phosphorylation of p53 by ATM in response to DNA damage
-
S. Banin, L. Moyal, S. Shieh, Y. Taya, C.W. Anderson, and L. Chessa Enhanced phosphorylation of p53 by ATM in response to DNA damage Science 281 1998 1674 1677
-
(1998)
Science
, vol.281
, pp. 1674-1677
-
-
Banin, S.1
Moyal, L.2
Shieh, S.3
Taya, Y.4
Anderson, C.W.5
Chessa, L.6
-
3
-
-
33847737716
-
DNA damage checkpoints: from initiation to recovery or adaptation
-
DOI 10.1016/j.ceb.2007.02.009, PII S0955067407000233
-
J. Bartek, and J. Lukas DNA damage checkpoints: from initiation to recovery or adaptation Curr Opin Cell Biol 19 2007 238 245 (Pubitemid 46386406)
-
(2007)
Current Opinion in Cell Biology
, vol.19
, Issue.2
, pp. 238-245
-
-
Bartek, J.1
Lukas, J.2
-
5
-
-
0033083377
-
The human MLH1 cDNA complements dna mismatch repair defects in Mlh1- deficient mouse embryonic fibroblasts
-
A.B. Buermeyer, C. Wilson-Van Patten, S.M. Baker, and R.M. Liskay The human MLH1 cDNA complements DNA mismatch repair defects in Mlh1-deficient mouse embryonic fibroblasts Cancer Res 59 1999 538 541 (Pubitemid 29076046)
-
(1999)
Cancer Research
, vol.59
, Issue.3
, pp. 538-541
-
-
Buermeyer, A.B.1
Wilson-Van Patten, C.2
Baker, S.M.3
Liskay, R.M.4
-
6
-
-
0032508608
-
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
-
DOI 10.1126/science.281.5383.1677
-
C.E. Canman, D.S. Lim, K.A. Cimprich, Y. Taya, K. Tamai, and K. Sakaguchi Activation of the ATM kinase by ionizing radiation and phosphorylation of p53 Science 281 1998 1677 1679 (Pubitemid 28435584)
-
(1998)
Science
, vol.281
, Issue.5383
, pp. 1677-1679
-
-
Canman, C.E.1
Lim, D.-S.2
Cimprich, K.A.3
Taya, Y.4
Tamai, K.5
Sakaguchi, K.6
Appella, E.7
Kastan, M.B.8
Siliciano, J.D.9
-
7
-
-
0034666155
-
Steady-state regulation of the human DNA mismatch repair system
-
D.K. Chang, L. Ricciardiello, A. Goel, C.L. Chang, and C.R. Boland Steady-state regulation of the human DNA mismatch repair system J Biol Chem 275 2000 29178
-
(2000)
J Biol Chem
, vol.275
, pp. 29178
-
-
Chang, D.K.1
Ricciardiello, L.2
Goel, A.3
Chang, C.L.4
Boland, C.R.5
-
8
-
-
47749141560
-
ATR: An essential regulator of genome integrity
-
DOI 10.1038/nrm2450, PII NRM2450
-
K.A. Cimprich, and D. Cortez ATR: an essential regulator of genome integrity Nat Rev Mol Cell Biol 9 2008 616 627 (Pubitemid 352032926)
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, Issue.8
, pp. 616-627
-
-
Cimprich, K.A.1
Cortez, D.2
-
9
-
-
25444517122
-
Good timing in the cell cycle for precise DNA repair by BRCA1
-
S.T Durant, and J.A. Nickoloff Good timing in the cell cycle for precise DNA repair by BRCA1 Cell Cycle 4 2005 1216 1222 (Pubitemid 41365391)
-
(2005)
Cell Cycle
, vol.4
, Issue.9
, pp. 1216-1222
-
-
Durant, S.T.1
Nickoloff, J.A.2
-
10
-
-
0038182453
-
A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein
-
DOI 10.1093/emboj/cdg274
-
N. Foray, D. Marot, A. Gabriel, V. Randrianarison, A.M. Carr, and M. Perricaudet A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein EMBO J 22 2003 2860 2871 (Pubitemid 36712381)
-
(2003)
EMBO Journal
, vol.22
, Issue.11
, pp. 2860-2871
-
-
Foray, N.1
Marot, D.2
Gabriel, A.3
Randrianarison, V.4
Carr, A.M.5
Perricaudet, M.6
Ashworth, A.7
Jeggo, P.8
-
11
-
-
0035907395
-
Ataxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. in vivo assessment using phospho-specific antibodies
-
M. Gatei, B.B. Zhou, K. Hobson, S. Scott, D. Young, and K.K. Khanna Ataxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment using phospho-specific antibodies J Biol Chem 276 2001 17276 17280
-
(2001)
J Biol Chem
, vol.276
, pp. 17276-17280
-
-
Gatei, M.1
Zhou, B.B.2
Hobson, K.3
Scott, S.4
Young, D.5
Khanna, K.K.6
-
12
-
-
0032701335
-
Assessment of pathogenicity criteria for constitutional missense mutations of the hereditary nonpolyposis colorectal cancer genes MLH1 and MSH2
-
DOI 10.1038/sj.ejhg.5200363
-
M. Genuardi, S. Carrara, M. Anti, M. Ponz de Leon, and A. Viel Assessment of pathogenicity criteria for constitutional missense mutations of the hereditary nonpolyposis colorectal cancer genes MLH1 and MSH2 Eur J Hum Genet 7 1999 778 782 (Pubitemid 29516236)
-
(1999)
European Journal of Human Genetics
, vol.7
, Issue.7
, pp. 778-782
-
-
Genuardi, M.1
Carrara, S.2
Anti, M.3
Ponz De Leon, M.4
Viel, A.5
-
13
-
-
0031456973
-
The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch
-
DOI 10.1016/S0092-8674(00)80490-0
-
S. Gradia, S. Acharya, and R. Fishel The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch Cell 91 1997 995 1005 (Pubitemid 28027832)
-
(1997)
Cell
, vol.91
, Issue.7
, pp. 995-1005
-
-
Gradia, S.1
Acharya, S.2
Fishel, R.3
-
14
-
-
77952876927
-
New advances in molecular mechanisms and the prevention of adriamycin toxicity by antioxidant nutrients
-
S. Granados-Principal, J.L. Quiles, C.L. Ramirez-Tortosa, P. Sanchez-Rovira, and M.C. Ramirez-Tortosa New advances in molecular mechanisms and the prevention of adriamycin toxicity by antioxidant nutrients Food Chem Toxicol 48 2010 1425 1438
-
(2010)
Food Chem Toxicol
, vol.48
, pp. 1425-1438
-
-
Granados-Principal, S.1
Quiles, J.L.2
Ramirez-Tortosa, C.L.3
Sanchez-Rovira, P.4
Ramirez-Tortosa, M.C.5
-
15
-
-
0034500024
-
DNA mismatch repair and genetic instability
-
DOI 10.1146/annurev.genet.34.1.359
-
B.D. Harfe, and S. Jinks-Robertson DNA mismatch repair and genetic instability Annu Rev Genet 34 2000 359 399 (Pubitemid 32065926)
-
(2000)
Annual Review of Genetics
, vol.34
, pp. 359-399
-
-
Harfe, B.D.1
Jinks-Robertson, S.2
-
16
-
-
0033612303
-
Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1
-
DOI 10.1016/S0092-8674(00)80769-2
-
D.P. Harkin, J.M. Bean, D. Miklos, Y.H. Song, V.B. Truong, and C. Englert Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1 Cell 97 1999 575 586 (Pubitemid 29256961)
-
(1999)
Cell
, vol.97
, Issue.5
, pp. 575-586
-
-
Harkin, D.P.1
Bean, J.M.2
Miklos, D.3
Song, Y.-H.4
Truong, V.B.5
Englert, C.6
Christians, F.C.7
Ellisen, L.W.8
Maheswaran, S.9
Oliner, J.D.10
Haber, D.A.11
-
17
-
-
38049150586
-
The DNA damage response pathways: At the crossroad of protein modifications
-
M.S. Huen, and J. Chen The DNA damage response pathways: at the crossroad of protein modifications Cell Res 18 2008 8 16
-
(2008)
Cell Res
, vol.18
, pp. 8-16
-
-
Huen, M.S.1
Chen, J.2
-
18
-
-
33646187811
-
The multifaceted mismatch-repair system
-
J. Jiricny The multifaceted mismatch-repair system Nat Rev Mol Cell Biol 7 2006 335 346
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 335-346
-
-
Jiricny, J.1
-
19
-
-
33746189409
-
Endonucleolytic Function of MutLα in Human Mismatch Repair
-
DOI 10.1016/j.cell.2006.05.039, PII S0092867406008129
-
F.A. Kadyrov, L. Dzantiev, N. Constantin, and P. Modrich Endonucleolytic function of MutLalpha in human mismatch repair Cell 126 2006 297 308 (Pubitemid 44092957)
-
(2006)
Cell
, vol.126
, Issue.2
, pp. 297-308
-
-
Kadyrov, F.A.1
Dzantiev, L.2
Constantin, N.3
Modrich, P.4
-
20
-
-
0141509882
-
Ataxia telangiectasia-mutated protein can regulate p53 and neuronal death independent of Chk2 in response to DNA damage
-
DOI 10.1074/jbc.M304049200
-
E. Keramaris, A. Hirao, R.S. Slack, T.W. Mak, and D.S. Park Ataxia telangiectasia-mutated protein can regulate p53 and neuronal death independent of Chk2 in response to DNA damage J Biol Chem 278 2003 37782 37789 (Pubitemid 37175305)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.39
, pp. 37782-37789
-
-
Keramaris, E.1
Hirao, A.2
Slack, R.S.3
Mak, T.W.4
Park, D.S.5
-
21
-
-
36148954290
-
MLH1- and ATM-dependent MAPK signaling is activated through c-Abl in response to the alkylator N-methyl-N′-nitro-N′-nitrosoguanidine
-
DOI 10.1074/jbc.M701451200
-
W.J. Kim, B. Rajasekaran, and K.D. Brown MLH1- and ATM-dependent MAPK signaling is activated through c-Abl in response to the alkylator N-methyl-N′-nitro-N′-nitrosoguanidine J Biol Chem 282 2007 32021 32031 (Pubitemid 350106463)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.44
, pp. 32021-32031
-
-
Kim, W.-J.1
Rajasekaran, B.2
Brown, K.D.3
-
24
-
-
21644469743
-
BRCA1 and transcription
-
T.F. Lane BRCA1 and transcription Cancer Biol Ther 3 2004 528 533 (Pubitemid 41351122)
-
(2004)
Cancer Biology and Therapy
, vol.3
, Issue.6
, pp. 528-533
-
-
Lane, T.F.1
-
25
-
-
0034717283
-
Identification of a second MutL DNA mismatch repair complex (hPMS1 and hMLH1) in human epithelial cells
-
DOI 10.1074/jbc.M908768199
-
W.K. Leung, J.J. Kim, L. Wu, J.L. Sepulveda, and A.R. Sepulveda Identification of a second MutL DNA mismatch repair complex (hPMS1 and hMLH1) in human epithelial cells J Biol Chem 275 2000 15728 15732 (Pubitemid 30366870)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.21
, pp. 15728-15732
-
-
Leung, W.K.1
Kim, J.J.2
Wu, L.3
Sepulveda, J.L.4
Sepulveda, A.R.5
-
26
-
-
0035878122
-
Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation
-
W.C. Lin, F.T. Lin, and J.R. Nevins Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation Genes Dev 15 2001 1833 1844 (Pubitemid 32905640)
-
(2001)
Genes and Development
, vol.15
, Issue.14
, pp. 1833-1844
-
-
Lin, W.-C.1
Lin, F.-T.2
Nevins, J.R.3
-
27
-
-
3042791562
-
ATM-mediated stabilization of hMutL DNA mismatch repair proteins augments p53 activation during DNA damage
-
DOI 10.1128/MCB.24.14.6430-6444.2004
-
Y. Luo, F.T. Lin, and W.C. Lin ATM-mediated stabilization of hMutL DNA mismatch repair proteins augments p53 activation during DNA damage Mol Cell Biol 24 2004 6430 6444 (Pubitemid 38891142)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.14
, pp. 6430-6444
-
-
Luo, Y.1
Lin, F.-T.2
Lin, W.-C.3
-
28
-
-
0034723347
-
BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression
-
DOI 10.1074/jbc.275.4.2777
-
T.K. MacLachlan, K. Somasundaram, M. Sgagias, Y. Shifman, R.J. Muschel, and K.H. Cowan BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression J Biol Chem 275 2000 2777 2785 (Pubitemid 30082049)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.4
, pp. 2777-2785
-
-
MacLachlan, T.K.1
Somasundaram, K.2
Sgagias, M.3
Shifman, Y.4
Muschel, R.J.5
Cowan, K.H.6
El-Deiry, W.S.7
-
29
-
-
0034306456
-
BRCA1: Exploring the links to transcription
-
A.N. Monteiro BRCA1: exploring the links to transcription Trends Biochem Sci 25 2000 469 474
-
(2000)
Trends Biochem Sci
, vol.25
, pp. 469-474
-
-
Monteiro, A.N.1
-
30
-
-
0029008683
-
GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells
-
F. Palombo, P. Gallinari, I. Iaccarino, T. Lettieri, M. Hughes, and A. D'Arrigo GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells Science 268 1995 1912 1914
-
(1995)
Science
, vol.268
, pp. 1912-1914
-
-
Palombo, F.1
Gallinari, P.2
Iaccarino, I.3
Lettieri, T.4
Hughes, M.5
D'Arrigo, A.6
-
31
-
-
0029659046
-
HMutSβ, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA
-
DOI 10.1016/S0960-9822(02)70685-4
-
F. Palombo, I. Iaccarino, E. Nakajima, M. Ikejima, T. Shimada, and J. Jiricny hMutSβ, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA Curr Biol 6 1996 1181 1184 (Pubitemid 26368752)
-
(1996)
Current Biology
, vol.6
, Issue.9
, pp. 1181-1184
-
-
Palombo, F.1
Iaccarino, I.2
Nakajima, E.3
Ikejima, M.4
Shimada, T.5
Jiricny, J.6
-
32
-
-
0242317842
-
Human mismatch-repair protein MutL homologue 1 (MLH1) interacts with Escherichia coli MutL and MutS in vivo and in vitro: A simple genetic system to assay MLH1 function
-
DOI 10.1042/BJ20021205
-
B. Quaresima, P. Alifano, P. Tassone, E.V. Avvedimento, F.S. Costanzo, and S. Venuta Human mismatch-repair protein MutL homologue 1 (MLH1) interacts with Escherichia coli MutL and MutS in vivo and in vitro: a simple genetic system to assay MLH1 function Biochem J 371 2003 183 189 (Pubitemid 36458092)
-
(2003)
Biochemical Journal
, vol.371
, Issue.1
, pp. 183-189
-
-
Quaresima, B.1
Alifano, P.2
Tassone, P.3
Avvedimento, E.V.4
Costanzo, F.S.5
Venuta, S.6
-
33
-
-
33746773788
-
In vitro analysis of genomic instability triggered by BRCA1 missense mutations
-
B. Quaresima, M.C. Faniello, F. Baudi, T. Crugliano, G. Cuda, and F. Costanzo In vitro analysis of genomic instability triggered by BRCA1 missense mutations Hum Mutat 27 2006 715
-
(2006)
Hum Mutat
, vol.27
, pp. 715
-
-
Quaresima, B.1
Faniello, M.C.2
Baudi, F.3
Crugliano, T.4
Cuda, G.5
Costanzo, F.6
-
34
-
-
58149265466
-
BRCA1 5083del19 mutant allele selectively up-regulates periostin expression in vitro and in vivo
-
B. Quaresima, F. Romeo, M.C. Faniello, M. Di Sanzo, C.G. Liu, and A. Lavecchia BRCA1 5083del19 mutant allele selectively up-regulates periostin expression in vitro and in vivo Clin Cancer Res 14 2008 6797 6803
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6797-6803
-
-
Quaresima, B.1
Romeo, F.2
Faniello, M.C.3
Di Sanzo, M.4
Liu, C.G.5
Lavecchia, A.6
-
35
-
-
0033527450
-
Identification of hMutL, a heterodimer of hMLH1 and hPMS1
-
M. Raschle, G. Marra, M. Nystrom-Lahti, P. Schar, and J. Jiricny Identification of hMutL, a heterodimer of hMLH1 and hPMS1 J Biol Chem 274 1999 32368 32375
-
(1999)
J Biol Chem
, vol.274
, pp. 32368-32375
-
-
Raschle, M.1
Marra, G.2
Nystrom-Lahti, M.3
Schar, P.4
Jiricny, J.5
-
36
-
-
0242442569
-
Dna Mismatch Repair: Molecular Mechanisms and Biological Function
-
DOI 10.1146/annurev.micro.57.030502.090847
-
M.J. Schofield, and P. Hsieh DNA mismatch repair: molecular mechanisms and biological function Annu Rev Microbiol 57 2003 579 608 (Pubitemid 37406637)
-
(2003)
Annual Review of Microbiology
, vol.57
, pp. 579-608
-
-
Schofield, M.J.1
Hsieh, P.2
-
37
-
-
0037365789
-
ATM and related protein kinases: Safeguarding genome integrity
-
DOI 10.1038/nrc1011
-
Y. Shiloh ATM and related protein kinases: safeguarding genome integrity Nat Rev Cancer 3 2003 155 168 (Pubitemid 37328868)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.3
, pp. 155-168
-
-
Shiloh, Y.1
-
38
-
-
0030759895
-
Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21(WAF1/CIP1)
-
DOI 10.1038/38291
-
K. Somasundaram, H. Zhang, Y.X. Zeng, Y. Houvras, Y. Peng, and H. Zhang Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK inhibitor p21WAF1/CiP1 Nature 389 1997 187 190 (Pubitemid 27400601)
-
(1997)
Nature
, vol.389
, Issue.6647
, pp. 187-190
-
-
Somasundaram, K.1
Zhang, H.2
Zeng, Y.-X.3
Mouvras, Y.4
Peng, Y.5
Zhang, H.6
Wu, G.S.7
Licht, J.D.8
Weber, B.L.9
El-Deiry, W.S.10
-
39
-
-
3242877915
-
The DNA double-strand break response pathway: Becoming more BRCAish than ever
-
DOI 10.1016/j.dnarep.2004.03.026, PII S1568786404000850
-
N.S. Ting, and W.H. Lee The DNA double-strand break response pathway: becoming more BRCAish than ever DNA Repair (Amst) 3 2004 935 944 (Pubitemid 38997935)
-
(2004)
DNA Repair
, vol.3
, Issue.8-9
, pp. 935-944
-
-
Ting, N.S.Y.1
Lee, W.-H.2
-
40
-
-
0036143918
-
Functional analysis of hMLH1 variants and HNPCC-related mutations using a human expression system
-
J. Trojan, S. Zeuzem, A. Randolph, C. Hemmerle, A. Brieger, and J. Raedle Functional analysis of hMLH1 variants and HNPCC-related mutations using a human expression system Gastroenterology 122 2002 211 219 (Pubitemid 34049209)
-
(2002)
Gastroenterology
, vol.122
, Issue.1
, pp. 211-219
-
-
Trojan, J.1
Zeuzem, S.2
Randolph, A.3
Hemmerle, C.4
Brieger, A.5
Raedle, J.6
Plotz, G.7
Jiricny, J.8
Marra, G.9
-
41
-
-
0034655991
-
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
-
Y. Wang, D. Cortez, P. Yazdi, N. Neff, S.J. Elledge, and J. Qin BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures Genes Dev 14 2000 927 939 (Pubitemid 30253002)
-
(2000)
Genes and Development
, vol.14
, Issue.8
, pp. 927-939
-
-
Wang, Y.1
Cortez, D.2
Yazdi, P.3
Neff, N.4
Elledge, S.J.5
Qin, J.6
-
42
-
-
17944370512
-
Adenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1
-
DOI 10.1038/sj.onc.1204625
-
Q. Wang, H. Zhang, S. Guerrette, J. Chen, A. Mazurek, and T. Wilson Adenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1 Oncogene 20 2001 4640 4649 (Pubitemid 32762436)
-
(2001)
Oncogene
, vol.20
, Issue.34
, pp. 4640-4649
-
-
Wang, Q.1
Zhang, H.2
Guerrette, S.3
Chen, J.4
Mazurek, A.5
Wilson, T.6
Slupianek, A.7
Skorski, T.8
Fishel, R.9
Greene, M.I.10
-
43
-
-
0034707047
-
The DNA damage response: Putting checkpoints in perspective
-
B.B. Zhou, and S.J. Elledge The DNA damage response: putting checkpoints in perspective Nature 408 2000 433 439
-
(2000)
Nature
, vol.408
, pp. 433-439
-
-
Zhou, B.B.1
Elledge, S.J.2
|