Development of a cultivation process for the enhancement of human interferon alpha 2b production in the oleaginous yeast, Yarrowia lipolytica

Microbial Cell Factories

Volumn 10, Issue , 2011, Pages

  Gasmi, Najla ^a,b   Ayed, Atef ^a   Ammar, Billel B H ^a   Zrigui, Rim ^a   Nicaud, Jean Marc ^b,c   Kallel, Héla ^a  

^a PASTEUR INSTITUTE OF TUNIS   (Tunisia)

^b UMR1319 MICALIS   (France)

^c CNRS   (France)

Author keywords

High cell density culture; Induction strategy; Pox2 promoter; Recombinant human interferon 2b; Yarrowia lipolytica

Indexed keywords

ALPHA2B INTERFERON; ASPARTIC PROTEINASE; OLEIC ACID; ALPHA INTERFERON; GLUCOSE; RECOMBINANT PROTEIN;

ARTICLE; BIOMASS; BIOREACTOR; CATABOLISM; CELL CULTURE; CELL DENSITY; CELL VIABILITY; DEGRADATION KINETICS; GLUCOSE INTAKE; PROTEIN EXPRESSION; YARROWIA LIPOLYTICA; BIOSYNTHESIS; EVALUATION; GENETIC ENGINEERING; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; METABOLISM; METHODOLOGY; MICROBIOLOGY; PROMOTER REGION; YARROWIA;

YARROWIA LIPOLYTICA;

BIOMASS; BIOREACTORS; GENETIC ENGINEERING; GLUCOSE; HUMANS; INDUSTRIAL MICROBIOLOGY; INTERFERON-ALPHA; OLEIC ACID; PROMOTER REGIONS, GENETIC; RECOMBINANT PROTEINS; YARROWIA;

EID: 80055116156     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/1475-2859-10-90     Document Type: Article

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