Juvenile cataract-associated mutation of solute carrier SLC16A12 impairs trafficking of the protein to the plasma membrane

Investigative Ophthalmology and Visual Science

Volumn 52, Issue 9, 2011, Pages 6774-6784

  Castorino, John J ^a   Gallagher Colombo, Shannon M ^a   Levin, Alex V ^b   Fitz, Paul G Gerald ^c   Polishook, Jessica ^a   Kloeckener Gruissem, Barbara ^d,e   Ostertag, Eric ^f,g,h   Philp, Nancy J ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b WILLS EYE HOSPITAL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF ZURICH   (Switzerland)

^e ETH ZURICH   (Switzerland)

^f Transposagen Biopharmaceuticals Inc   (United States)

^g UNIVERSITY OF KENTUCKY   (United States)

^h UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD147 ANTIGEN; MONOCARBOXYLATE TRANSPORTER; MONOCARBOXYLATE TRANSPORTER 1; MONOCARBOXYLATE TRANSPORTER 12; MONOCARBOXYLATE TRANSPORTER 4; UNCLASSIFIED DRUG; DNA; SLC16A12 PROTEIN, HUMAN;

ANIMAL TISSUE; ANIMLA EXPERIMENT; ARTICLE; BIOTINYLATION; CATARACT; CELL MEMBRANE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GENE; GENE LOSS; GENE MUTATION; GENOTYPE; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOPRECIPITATION; LENS EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; SLC16A12 GENE; SLIT LAMP; WESTERN BLOTTING; ACOUSTIC MICROSCOPY; AGING; ANIMAL; C57BL MOUSE; CELL CULTURE; COMPARATIVE STUDY; DISEASE MODEL; EPITHELIUM; FISCHER 344 RAT; GENE EXPRESSION; GENETICS; IMMUNOBLOTTING; LENS; METABOLISM; MUTATION; NEWBORN; PATHOLOGY; PROTEIN TRANSPORT; ULTRASTRUCTURE;

AGING; ANIMALS; ANIMALS, NEWBORN; CATARACT; CELL MEMBRANE; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DNA; EPITHELIUM; GENE EXPRESSION; GENOTYPE; IMMUNOBLOTTING; IMMUNOPRECIPITATION; LENS, CRYSTALLINE; MICE; MICE, INBRED C57BL; MICROSCOPY, ACOUSTIC; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; MONOCARBOXYLIC ACID TRANSPORTERS; MUTATION; PROTEIN TRANSPORT; RATS; RATS, INBRED F344; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 80055070320     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.10-6579     Document Type: Article

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