Optimization, in-house validation, and application of a liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based method for the quantification of selected polyphenolic compounds in leaves of grapevine (Vitis vinifera L.)

Journal of Agricultural and Food Chemistry

Volumn 59, Issue 20, 2011, Pages 10787-10794

  Schoedl, Katharina ^a   Forneck, Astrid ^a   Sulyok, Michael ^b   Schuhmacher, Rainer ^b  

^a UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^b UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

Author keywords

Grapevine; LC MS MS; leaves; polyphenols

Indexed keywords

CINNAMIC ACIDS; CONCENTRATION LEVELS; ENVIRONMENTAL INFLUENCES; ENVIRONMENTAL STRESS; FAST TOOL; GRAPEVINE; LC-MS/MS; LEAVES; LIMITS OF QUANTIFICATION; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; PERFORMANCE CHARACTERISTICS; PINOT NOIR; PLANT ORGANS; POLYPHENOLIC COMPOUND; POLYPHENOLS; SAMPLE CLEAN-UP; SIMULTANEOUS SEPARATION; TRANS-RESVERATROL; VITIS VINIFERA;

FRUITS; LIQUIDS; MASS SPECTROMETRY; OPTIMIZATION; PHENOLS; WINE;

LIQUID CHROMATOGRAPHY;

CINNAMIC ACID DERIVATIVE; FLAVONOID; POLYPHENOL; STILBENE DERIVATIVE;

ARTICLE; CHEMISTRY; COMPARATIVE STUDY; LIQUID CHROMATOGRAPHY; METHODOLOGY; PLANT LEAF; SPECIES DIFFERENCE; TANDEM MASS SPECTROMETRY; VALIDATION STUDY; VITIS;

CHROMATOGRAPHY, LIQUID; CINNAMATES; FLAVONOIDS; PLANT LEAVES; POLYPHENOLS; SPECIES SPECIFICITY; STILBENES; TANDEM MASS SPECTROMETRY; VITIS;

VITIS; VITIS VINIFERA;

EID: 80055001424     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf202753g     Document Type: Article

References (44)

1. Vermerris, W.; Nicholson, R. L. Phenolic Compound Biochemistry; Springer: Dordrecht, The Netherlands, 2006.
2. Langcake, P.; Pryce, R. J. The production of resveratrol by Vitis vinifera and other members of the Vitaceae as a response to infection or injury Physiol. Plant Pathol. 1976, 9 (1) 77-86
3. Kolb, C. A.; Käser, M. A.; Kopecký, J.; Zotz, G.; Riederer, M.; Pfündel, E. E. Effects of natural intensities of visible and ultraviolet radioation on epidermal ultraviolet screening and photosynthesis in grape leaves Plant Physiol. 2001, 127, 863-875 (Pubitemid 33112148)
4. Kolb, C. A.; Kopecký, J.; Riederer, M.; Pfündel, E. E. UV screening by phenolics in berries of grapevine (Vitis vinifera) Funct. Plant Biol. 2003, 30 (12) 1177-1186 (Pubitemid 38184753)
5. Frémont, L. Biological effects of resveratrol Life Sci. 2000, 66 (8) 663-673
6. Gao, L.; Mazza, G. Quantitation and distribution of simple and acylated anthocyanins and other phenolics in blueberries J. Food Sci. 1994, 59 (5) 1057-1059
7. Stockley, C. S.; Høj, P. B. Better wine for better health: Fact or fiction? Aust. J. Grape Wine Res. 2005, 11 (2) 127-138 (Pubitemid 41080326)
8. Hagen, S. F.; Borge, G. I. A.; Solhaug, K. A.; Bengtsson, G. B. Effect of cold storage and harvest date on bioactive compounds in curly kale (Brassica oleracea L. var. acephala) Postharvest Biol. Technol. 2009, 51 (1) 36-42
9. Koponen, J. M.; Happonen, A. M.; Mattila, P. H.; Torronen, A. R. Contents of anthocyanins and ellagitannins in selected foods consumed in Finland J. Agric. Food Chem. 2007, 55 (4) 1612-1619
10. Mattila, P.; Hellstrom, J.; Torronen, R. Phenolic acids in berries, fruits, and beverages J. Agric. Food Chem. 2006, 54 (19) 7193-7199 (Pubitemid 44554940)
11. García-Beneytez, E.; Revilla, E.; Cabello, F. Anthocyanin pattern of several red grape cultivars and wines made from them Eur. Food Res. Technol. 2002, 215 (1) 32-37
12. Cortell, J. M.; Halbleib, M.; Gallagher, A. V.; Righetti, T. L.; Kennedy, J. A. Influence of vine vigor on grape (Vitis vinifera L. cv. Pinot noir) anthocyanins. 1. Anthocyanin concentration and composition in fruit J. Agric. Food Chem. 2007, 55 (16) 6575-6584 (Pubitemid 47280033)
13. Delgado, R.; Martín, P.; Del Álamo, M.; González, M.-R. Changes in the phenolic composition of grape berries during ripening in relation to vineyard nitrogen and potassium fertilisation rates J. Sci. Food Agric. 2004, 84 (7) 623-630 (Pubitemid 38600632)
14. Makris, D.; Boskou, G.; Andrikopoulos, N.; Kefalas, P. Characterisation of certain major polyphenolic antioxidants in grape (Vitis vinifera cv. Roditis) stems by liquid chromatography-mass spectrometry Eur. Food Res. Technol. 2008, 226 (5) 1075-1079 (Pubitemid 351214713)
15. Doshi, P.; Adsule, P.; Banerjee, K. Phenolic composition and antioxidant activity in grapevine parts and berries (Vitis vinifera L.) cv. Kishmish Chornyi (Sharad Seedless) during maturation Int. J. Food Sci. Technol. 2006, 41 (S1) 1-9 (Pubitemid 44181395)
16. Püssa, T.; Floren, J.; Kuldkepp, P.; Raal, A. Survey of grapevine Vitis vinifera stem polyphenols by liquid chromatography-diode array detection-tandem mass spectrometry J. Agric. Food Chem. 2006, 54 (20) 7488-7494 (Pubitemid 44645762)
17. Liakopoulos, G.; Nikolopoulos, D.; Klouvatou, A.; Vekkos, K.-A.; Manetas, Y.; Karabourniotis, G. The photoprotective role of epidermal anthocyanins and surface pubescence in young leaves of grapevine (Vitis vinifera) Ann. Bot. 2006, 98 (1) 257-265 (Pubitemid 43999615)
18. Andreotti, C.; Costa, G.; Treutter, D. Composition of phenolic compounds in pear leaves as affected by genetics, ontogenesis and the environment Sci. Hortic. 2006, 109 (2) 130-137 (Pubitemid 43737048)
19. Barreto, J. C.; Trevisan, M. T. S.; Hull, W. E.; Erben, G.; de Brito, E. S.; Pfundstein, B.; Würtele, G.; Spiegelhalder, B.; Owen, R. W. Characterization and quantitation of polyphenolic compounds in bark, kernel, leaves, and peel of mango (Mangifera indica L.) J. Agric. Food Chem. 2008, 56 (14) 5599-5610
20. Park, H.-J.; Cha, H.-C. Flavonoids from leaves and exocarps of the Grape Kyoho Korean J. Biol. Sci. 2003, 7, 327-330
21. Kammerer, D.; Claus, A.; Carle, R.; Schieber, A. Polyphenol screening of pomace from red and white grape varieties (Vitis vinifera L.) by HPLC-DAD-MS/MS J. Agric. Food Chem. 2004, 52 (14) 4360-4367
22. García-Beneytez, E.; Cabello, F.; Revilla, E. Analysis of grape and wine anthocyanins by HPLC-MS J. Agric. Food Chem. 2003, 51 (19) 5622-5629
23. Heier, A.; Blaas, W.; Dross, A.; Wittkowski, R. Anthocyanin analysis by HPLC/ESI-MS Am. J. Enol. Vitic. 2002, 53 (1) 78-86 (Pubitemid 34553914)
24. Sulyok, M.; Berthiller, F.; Krska, R.; Schuhmacher, R. Development and validation of a liquid chromatography/tandem mass spectrometric method for the determination of 39 mycotoxins in wheat and maize Rapid Commun. Mass Spectrom. 2006, 20 (18) 2649-2659 (Pubitemid 44497392)
25. Wegscheider, W.; Rohrer, C.; Neuböck, R. ValiData (Excel Macro for Method Validation), version 3.02.48, 1999.
26. Stobiecki, M.; Skirycz, A.; Kerhoas, L.; Kachlicki, P.; Muth, D.; Einhorn, J.; Mueller-Roeber, B. Profiling of phenolic glycosidic conjugates in leaves of Arabidopsis thaliana using LC/MS Metabolomics 2006, 2 (4) 197-219 (Pubitemid 46099799)
27. Oh, Y. S.; Lee, J. H.; Yoon, S. H.; Oh, C. H.; Choi, D. S.; Choe, E.; Jung, M. Y. Characterization and quantification of anthocyanins in grape juices obtained from the grapes cultivated in Korea by HPLC/DAD, HPLC/MS, and HPLC/MS/MS J. Food Sci. 2008, 73 (5) C378-C389
28. Wang, H.; Zhao, M.; Yang, B.; Jiang, Y.; Rao, G. Identification of polyphenols in tobacco leaf and their antioxidant and antimicrobial activities Food Chem. 2008, 107 (4) 1399-1406 (Pubitemid 350166757)
29. Bystrom, L. M.; Lewis, B. A.; Brown, D. L.; Rodriguez, E.; Obendorf, R. L. Characterisation of phenolics by LC-UV/vis, LC-MS/MS and sugars by GC in Melicoccus bijugatus Jacq. 'Montgomery' fruits Food Chem. 2008, 111 (4) 1017-1024
30. Djoukeng, J. D.; Arbona, V.; Argamasilla, R.; Gomez-Cadenas, A. Flavonoid profiling in leaves of citrus genotypes under different environmental situations J. Agric. Food Chem. 2008, 56 (23) 11087-11097
31. n and HPLC/DAD-UV Food Chem. 2011, 127 (2) 727-734
32. Ali, A.; Strommer, J. A simple extraction and chromatographic system for the simultaneous analysis of anthocyanins and stilbenes of Vitis species J. Agric. Food Chem. 2003, 51 (25) 7246-7251
33. Vitrac, X.; Bornet, A.; Vanderlinde, R.; Valls, J.; Richard, T.; Delaunay, J.-C.; Merillon, J.-M.; Teissedre, P.-L. Determination of stilbenes (δ-viniferin, trans -astringin, trans -piceid, cis-and trans -resveratrol, ε-viniferin) in Brazilian wines J. Agric. Food Chem. 2005, 53 (14) 5664-5669 (Pubitemid 41022461)
34. Pezet, R.; Perret, C.; Jean-Denis, J. B.; Tabacchi, R.; Gindro, K.; Viret, O. δ-Viniferin, a resveratrol dehydrodimer: One of the major stilbenes synthesized by stressed grapevine leaves J. Agric. Food Chem. 2003, 51 (18) 5488-5492
35. Jean-Denis, J. B.; Pezet, R.; Tabacchi, R. Rapid analysis of stilbenes and derivatives from downy mildew-infected grapevine leaves by liquid chromatography-atmospheric pressure photoionisation mass spectrometry J. Chromatogr., A 2006, 1112 (1-2) 263-268
36. Poutaraud, A.; Latouche, G.; Martins, S.; Meyer, S.; Merdinoglu, D.; Cerovic, Z. G. Fast and local assessment of stilbene content in grapevine leaf by in vivo fluorometry J. Agric. Food Chem. 2007, 55 (13) 4913-4920 (Pubitemid 47056035)
37. Flamini, R. Mass spectrometry in grape and wine chemistry. Part I: Polyphenols Mass Spectrom. Rev. 2003, 22 (4) 218-250
38. Fux, E.; Rode, D.; Bire, R.; Hess, P. Approaches to the evaluation of matrix effects in the liquid chromatography-mass spectrometry (LC-MS) analysis of three regulated lipophilic toxin groups in mussel matrix (Mytilus edulis) Food Addit. Contam., Part A 2008, 25 (8) 1024-1032 (Pubitemid 352044637)
39. Matuszewski, B. K.; Constanzer, M. L.; Chavez-Eng, C. M. Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS Anal. Chem. 2003, 75 (13) 3019-3030 (Pubitemid 36830428)
40. Kilcoyne, J.; Fux, E. Strategies for the elimination of matrix effects in the liquid chromatography tandem mass spectrometry analysis of the lipophilic toxins okadaic acid and azaspiracid-1 in molluscan shellfish J. Chromatogr., A 2010, 1217, 7123-7130
41. Cantos, E.; Garcia-Viguera, C.; de Pascual-Teresa, S.; Tomas-Barberan, F. A. Effect of postharvest ultraviolet irradiation on resveratrol and other phenolics of cv. Napoleon table grapes J. Agric. Food Chem. 2000, 48 (10) 4606-4612
42. Berli, F.; D'Angelo, J.; Cavagnaro, B.; Bottini, R.; Wuilloud, R.; Silva, M. F. Phenolic composition in grape (Vitis vinifera L. cv. Malbec) ripened with different solar UV-B radiation levels by capillary zone electrophoresis J. Agric. Food Chem. 2008, 56 (9) 2892-2898 (Pubitemid 351746005)
43. Dixon, R. A.; Paiva, N. L. Stress-induced phenylpropanoid metabolism Plant Cell 1995, 7 (7) 1085-1097
44. Jordan, B. R.; James, P. E.; Mackerness, S. A. H. Factors affecting UV-B-induced changes in Arabidopsis thaliana L. gene expression: The role of development, protective pigments and the chloroplast signal Plant Cell Physiol. 1998, 39 (7) 769-778 (Pubitemid 28348844)