Approaches to the evaluation of matrix effects in the liquid chromatography-mass spectrometry (LC-MS) analysis of three regulated lipophilic toxin groups in mussel matrix (Mytilus edulis)

Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment

Volumn 25, Issue 8, 2008, Pages 1024-1032

  Fux, E ^a,b   Rode, D ^c   Bire, R ^a   Hess, P ^a  

^a MARINE INSTITUTE   (Ireland)

^b DUBLIN INSTITUTE OF TECHNOLOGY   (Ireland)

^c UNIVERSITY OF APPLIED SCIENCES   (Germany)

Author keywords

Azaspiracid 1 (AZA1); Liquid chromatography mass spectrometry (LC MS); Matrix effects; Okadaic acid (OA); Pectenotoxin 2 (PTX2); Ultra performance liquid chromatography (UPLC) mass spectrometry (MS)

Indexed keywords

AZASPIRACID; MARINE TOXIN; OKADAIC ACID; PECTENOTOXIN 2; TOXIN; AZASPIRACID 1; UNCLASSIFIED DRUG;

ARTICLE; CHROMATOGRAPHY; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; COOKED FOOD; DILUTION; ELUTION; FOOD ANALYSIS; FOOD CONTAMINATION; LIPOPHILICITY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MUSSEL; NONHUMAN; PRIORITY JOURNAL; TOXIN ANALYSIS; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANALYTIC METHOD; CHEMICAL ANALYSIS; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; FOOD CONTAMINATION; FURANS; HOT TEMPERATURE; MARINE TOXINS; MASS SPECTROMETRY; MYTILUS EDULIS; OKADAIC ACID; PYRANS; SPIRO COMPOUNDS;

ANIMALIA; MYTILUS EDULIS;

EID: 47949112524     PISSN: 19440049     EISSN: 19440057     Source Type: Journal    
DOI: 10.1080/02652030802008601     Document Type: Article

References (19)

1. Aasen, J, Samdal, IA, Miles, CO, Dahl, E, Briggs, LR, and Aune, T. 2005. Yessotoxins in Norwegian blue mussels (Mytilus edulis):uptake from Protoceratium reticulatum, metabolism and depuration. Toxicon, 45:265–272.
2. Anon. 2001. FDA guidance for industry bioanalytical method validation [Internet] USA [cited 2008 Feb 13]. Available from:http://www.fda.gov/CDER/GUIDANCE/4252fnl.htm/
3. Anon. 2004. Regulation (EC) No. 853/2004. Off J Eur Union,:22–82. L226
4. Anon. 2005. Commission regulation (EC) No. 2074/2005. Off J Eur Union,:27–59. L338
5. Careri, M, and Mangia, A. 2006. Validation and qualification:the fitness for purpose of mass spectrometry-based analytical methods and analytical systems. Anal Bioanal Chem, 386:38–45.
6. Ciminiello, P, Dell’Aversano, C, Fattorusso, E, Forino, M, Magno, S, Guerrini, F, Pistocchi, R, and Boni, L. 2003. Complex yessotoxins profile in Protoceratium reticulatum from north-western Adriatic sea revealed by LC-MS analysis. Toxicon, 42:7–14.
7. Draisci, R, Palleschi, L, Giannetti, L, Lucentini, L, James, KJ, Bishop, AG, Satake, M, and Yasumoto, T. 1999. New approach to the direct detection of known and new diarrhoeic shellfish toxins in mussels and phytoplankton by liquid chromatography-mass spectrometry. J Chromatogr A, 847:213–221.
8. Fernandez Amandi, M, Furey, A, Lehane, M, Ramstad, H, and James, KJ. 2002. Liquid chromatography with electrospray ion-trap mass spectrometry for the determination of yessotoxins in shellfish. J Chromatogr A, 976:329–334.
9. Fux, E, McMillan, D, Bire, R, and Hess, P. 2007. Development of an ultra-performance liquid chromatography-mass spectrometry method for the detection of lipophilic marine toxins. J Chromatogr A, 1157:273–280.
10. Goto, H, Igarashi, T, Yamamoto, M, Yasuda, M, Sekiguchi, R, Watai, M, Tanno, K, and Yasumoto, T. 2001. Quantitative determination of marine toxins associated with diarrhetic shellfish poisoning by liquid chromatography coupled with mass spectrometry. J Chromatogr A, 907:181–189.
11. Ito, S, and Tsukada, K. 2002. Matrix effect and correction by standard addition in quantitative liquid chromatographic-mass spectrometric analysis of diarrhetic shellfish poisoning toxins. J Chromatogr A, 943:39–46.
12. James, KJ, Bishop, AG, Draisci, R, Palleschi, L, Marchiafava, C, Ferretti, E, Satake, M, and Yasumoto, T. 1999. Liquid chromatographic methods for the isolation and identification of new pectenotoxin-2 analogues from marine phytoplankton and shellfish. J Chromatogr A, 844:53–65.
13. King, R, Bonfiglio, R, Fernandez-Metzler, C, Miller-Stein, C, and Olah, T. 2000. Mechanistic investigation of ionization suppression in electrospray ionization. J Am Soc Mass Spectrom, 11:942–950.
14. MacKenzie, L, Holland, P, McNabb, P, Beuzenberg, V, Selwood, A, and Suzuki, T. 2002. Complex toxin profiles in phytoplankton and Greenshell mussels (Perna canaliculus), revealed by LC-MS/MS analysis. Toxicon, 40:1321–1330.
15. McNabb, P, Selwood, AI, Holland, PT, Aasen, J, Aune, T, Eaglesham, G, Hess, P, Igarishi, M, Quilliam, M, Slattery, D. 2005. Multiresidue method for determination of algal toxins in shellfish:single-laboratory validation and interlaboratory study. J AOAC Int, 88:761–772.
16. Miles, CO, Samdal, IA, Aasen, JAG, Jensen, DJ, Quilliam, MA, Petersen, D, Briggs, LM, Wilkins, AL, Rise, F, Cooney, JM. 2005. Evidence for numerous analogs of yessotoxin in Protoceratium reticulatum. Harmful Algae, 4:1075–1091.
17. Stobo, LA, Lacaze, JPCL, Scott, AC, Gallagher, S, Smith, EA, and Quilliam, MA. 2005. Liquid chromatography with mass spectrometry-detection of lipophilic shellfish toxins. J AOAC Int, 88:1371–1382.
18. Tang, L, and Kebarle, P. 1993. Dependence of ion intensity in electrospray mass spectrometry on the concentration of analytes in the electrosprayed solution. Anal Chem, 65:3654–3668.
19. Vale, P, and Sampayo, MAdM. 2002. Pectenotoxin-2 seco acid, 7-epi-pectenotoxin-2 seco acid and pectenotoxin-2 in shellfish and plankton from Portugal. Toxicon, 40:979–987.