메뉴 건너뛰기




Volumn 321, Issue 3-4, 2011, Pages 207-215

Effect of emamectin benzoate on transcriptional expression of cytochromes P450 and the multidrug transporters (Pgp and MRP1) in rainbow trout (Oncorhynchus mykiss) and the sea lice Caligus rogercresseyi

Author keywords

Caligus rogercresseyi; Cytochrome P450; Emamectin benzoate; Multidrug resistance proteins

Indexed keywords

ANTIBODY; CHEMICAL ANALYSIS; CHEMICAL CONTROL; CYTOCHROME; DRUG RESISTANCE; GENE EXPRESSION; LOUSE; METABOLISM; MITOCHONDRIAL DNA; POLYMERASE CHAIN REACTION; PROTEIN; REAL TIME; SALMONID FISHERY; SOUTHERN HEMISPHERE; XENOBIOTICS;

EID: 80055000779     PISSN: 00448486     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquaculture.2011.09.012     Document Type: Article
Times cited : (30)

References (56)
  • 1
    • 0343035568 scopus 로고    scopus 로고
    • Xenobiotic and steroid biotransformation enzymes in Atlantic salmon (Salmo salar) liver treated with an estrogenic compound, 4-nonylphenol
    • Arukwe A., Förlin L., Goksøyr A. Xenobiotic and steroid biotransformation enzymes in Atlantic salmon (Salmo salar) liver treated with an estrogenic compound, 4-nonylphenol. Environ. Toxicol. Chem. 1997, 16:2576-2583.
    • (1997) Environ. Toxicol. Chem. , vol.16 , pp. 2576-2583
    • Arukwe, A.1    Förlin, L.2    Goksøyr, A.3
  • 2
    • 0034821939 scopus 로고    scopus 로고
    • Role of transport proteins in drug absorption, distribution and excretion
    • Ayrton A., Morgan P. Role of transport proteins in drug absorption, distribution and excretion. Xenobiotica 2001, 31:469-497.
    • (2001) Xenobiotica , vol.31 , pp. 469-497
    • Ayrton, A.1    Morgan, P.2
  • 3
    • 2442719906 scopus 로고    scopus 로고
    • Unmasking the dynamic interplay between efflux transporters and metabolic enzymes
    • Benet L.Z., Cummins C.L., Wu C.Y. Unmasking the dynamic interplay between efflux transporters and metabolic enzymes. Int. J. Pharm. 2004, 277:3-9.
    • (2004) Int. J. Pharm. , vol.277 , pp. 3-9
    • Benet, L.Z.1    Cummins, C.L.2    Wu, C.Y.3
  • 4
    • 0034354576 scopus 로고    scopus 로고
    • On the identity of the common Caligus (Copepoda: Siphonostomatoida: Caligidae) from salmonid netpen systems in southern Chile
    • Boxshall G.A., Bravo S. On the identity of the common Caligus (Copepoda: Siphonostomatoida: Caligidae) from salmonid netpen systems in southern Chile. Contributions to Zoology 2000, 69.
    • (2000) Contributions to Zoology , vol.69
    • Boxshall, G.A.1    Bravo, S.2
  • 5
    • 50649097433 scopus 로고    scopus 로고
    • Sensitivity assessment of Caligus rogercresseyi to emamectin benzoate in Chile
    • Bravo S., Sevatdal S., Horsberg T. Sensitivity assessment of Caligus rogercresseyi to emamectin benzoate in Chile. Aquaculture 2008, 282:7-12.
    • (2008) Aquaculture , vol.282 , pp. 7-12
    • Bravo, S.1    Sevatdal, S.2    Horsberg, T.3
  • 6
    • 37349020802 scopus 로고    scopus 로고
    • Avermectin transepithelial transport in MDR1- and MRP-transfected canine kidney monolayers
    • Brayden D.J., Griffin J. Avermectin transepithelial transport in MDR1- and MRP-transfected canine kidney monolayers. Vet. Res. Commun. 2008, 32:93-106.
    • (2008) Vet. Res. Commun. , vol.32 , pp. 93-106
    • Brayden, D.J.1    Griffin, J.2
  • 7
    • 77956176464 scopus 로고    scopus 로고
    • In situ biomonitoring of juvenile Chinook salmon (Onchorhynchus tshawytscha) using biomarkers of chemical exposures and effects in a partially remediated urbanized waterway of the Puget Sound, WA
    • Browne E., Kelley M., Zhou G.D., He L.Y., McDonald T., Wang S., Duncan B., Meador J., Donnelly K., Gallagher E. In situ biomonitoring of juvenile Chinook salmon (Onchorhynchus tshawytscha) using biomarkers of chemical exposures and effects in a partially remediated urbanized waterway of the Puget Sound, WA. Environ. Res. 2010, 110:675-683.
    • (2010) Environ. Res. , vol.110 , pp. 675-683
    • Browne, E.1    Kelley, M.2    Zhou, G.D.3    He, L.Y.4    McDonald, T.5    Wang, S.6    Duncan, B.7    Meador, J.8    Donnelly, K.9    Gallagher, E.10
  • 8
    • 0034666844 scopus 로고    scopus 로고
    • Effects of 17beta-estradiol and testosterone on hepatic mRNA/protein levels and catalytic activities of CYP2M1, CYP2K1, and CYP3A27 in rainbow trout (Oncorhynchus mykiss)
    • Buhler D.R., Miranda C.L., Henderson M.C., Yang Y.H., Lee S.J., Wang-Buhler J.L. Effects of 17beta-estradiol and testosterone on hepatic mRNA/protein levels and catalytic activities of CYP2M1, CYP2K1, and CYP3A27 in rainbow trout (Oncorhynchus mykiss). Toxicol. Appl. Pharmacol. 2000, 168:91-101.
    • (2000) Toxicol. Appl. Pharmacol. , vol.168 , pp. 91-101
    • Buhler, D.R.1    Miranda, C.L.2    Henderson, M.C.3    Yang, Y.H.4    Lee, S.J.5    Wang-Buhler, J.L.6
  • 9
    • 0031770433 scopus 로고    scopus 로고
    • Rainbow trout cytochrome P450s: purification, molecular aspects, metabolic activity, induction and role in environmental monitoring
    • Buhler D.R., Wang-Buhler J.L. Rainbow trout cytochrome P450s: purification, molecular aspects, metabolic activity, induction and role in environmental monitoring. Comp. Biochem. Physiol. C Pharmacol. Toxicol. Endocrinol. 1998, 121:107-137.
    • (1998) Comp. Biochem. Physiol. C Pharmacol. Toxicol. Endocrinol. , vol.121 , pp. 107-137
    • Buhler, D.R.1    Wang-Buhler, J.L.2
  • 10
    • 33749267293 scopus 로고    scopus 로고
    • Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs
    • Cascorbi I. Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs. Pharmacol. Ther. 2006, 112:457-473.
    • (2006) Pharmacol. Ther. , vol.112 , pp. 457-473
    • Cascorbi, I.1
  • 11
    • 34248663955 scopus 로고    scopus 로고
    • The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: twenty-something years on
    • Chomczynski P., Sacchi N. The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: twenty-something years on. Nat. Protoc. 2006, 1:581-585.
    • (2006) Nat. Protoc. , vol.1 , pp. 581-585
    • Chomczynski, P.1    Sacchi, N.2
  • 12
    • 0036890399 scopus 로고    scopus 로고
    • The cytochrome P450 superfamily: biochemistry, evolution and drug metabolism in humans
    • Danielson P.B. The cytochrome P450 superfamily: biochemistry, evolution and drug metabolism in humans. Curr. Drug Metab. 2002, 3:561-597.
    • (2002) Curr. Drug Metab. , vol.3 , pp. 561-597
    • Danielson, P.B.1
  • 13
    • 0033739238 scopus 로고    scopus 로고
    • A review of the use of ivermectin as a treatment for sea lice [Lepeophtheirus salmonis (Krøyer) and Caligus elongatus Nordmann] infestation in farmed Atlantic salmon (Salmo salar L.)
    • Davies I.M.R.G.K. A review of the use of ivermectin as a treatment for sea lice [Lepeophtheirus salmonis (Krøyer) and Caligus elongatus Nordmann] infestation in farmed Atlantic salmon (Salmo salar L.). Aquaculture Research 2000, 31:869-883.
    • (2000) Aquaculture Research , vol.31 , pp. 869-883
    • Davies, I.M.R.G.K.1
  • 14
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman M.M., Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu. Rev. Biochem. 1993, 62:385-427.
    • (1993) Annu. Rev. Biochem. , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 15
    • 0036272839 scopus 로고    scopus 로고
    • Medicines for sea lice
    • Grant A.N. Medicines for sea lice. Pest Manag. Sci. 2002, 58:521-527.
    • (2002) Pest Manag. Sci. , vol.58 , pp. 521-527
    • Grant, A.N.1
  • 16
    • 0032924934 scopus 로고    scopus 로고
    • Cytochrome P-450 3A4: regulation and role in drug metabolism
    • Guengerich F.P. Cytochrome P-450 3A4: regulation and role in drug metabolism. Annu. Rev. Pharmacol. Toxicol. 1999, 39:1-17.
    • (1999) Annu. Rev. Pharmacol. Toxicol. , vol.39 , pp. 1-17
    • Guengerich, F.P.1
  • 17
    • 1842735382 scopus 로고    scopus 로고
    • Effects of alkylphenols on CYP1A and CYP3A expression in first spawning Atlantic cod (Gadus morhua)
    • Hasselberg L., Meier S., Svardal A., Hegelund T., Celander M.C. Effects of alkylphenols on CYP1A and CYP3A expression in first spawning Atlantic cod (Gadus morhua). Aquat. Toxicol. 2004, 67:303-313.
    • (2004) Aquat. Toxicol. , vol.67 , pp. 303-313
    • Hasselberg, L.1    Meier, S.2    Svardal, A.3    Hegelund, T.4    Celander, M.C.5
  • 18
    • 0033849976 scopus 로고    scopus 로고
    • Cellular and molecular aspects of drug transport in the kidney
    • Inui K.I., Masuda S., Saito H. Cellular and molecular aspects of drug transport in the kidney. Kidney Int. 2000, 58:944-958.
    • (2000) Kidney Int. , vol.58 , pp. 944-958
    • Inui, K.I.1    Masuda, S.2    Saito, H.3
  • 19
    • 0030063480 scopus 로고    scopus 로고
    • Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump
    • Jedlitschky G., Leier I., Buchholz U., Barnouin K., Kurz G., Keppler D. Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump. Cancer Res. 1996, 56:988-994.
    • (1996) Cancer Res. , vol.56 , pp. 988-994
    • Jedlitschky, G.1    Leier, I.2    Buchholz, U.3    Barnouin, K.4    Kurz, G.5    Keppler, D.6
  • 20
    • 33645830172 scopus 로고
    • A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
    • Juliano R.L., Ling V. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim. Biophys. Acta 1976, 455:152-162.
    • (1976) Biochim. Biophys. Acta , vol.455 , pp. 152-162
    • Juliano, R.L.1    Ling, V.2
  • 22
    • 17144465167 scopus 로고    scopus 로고
    • ATP-dependent transport of glutathione S-conjugates by the multidrug resistance protein MRP1 and its apical isoform MRP2
    • Keppler D., Leier I., Jedlitschky G., Konig J. ATP-dependent transport of glutathione S-conjugates by the multidrug resistance protein MRP1 and its apical isoform MRP2. Chem. Biol. Interact. 1998, 111-112:153-161.
    • (1998) Chem. Biol. Interact. , pp. 153-161
    • Keppler, D.1    Leier, I.2    Jedlitschky, G.3    Konig, J.4
  • 23
    • 0041331790 scopus 로고    scopus 로고
    • P-glycoprotein in helminths: function and perspectives for anthelmintic treatment and reversal of resistance
    • Kerboeuf D., Blackhall W., Kaminsky R., von Samson-Himmelstjerna G. P-glycoprotein in helminths: function and perspectives for anthelmintic treatment and reversal of resistance. Int. J. Antimicrob. Agents 2003, 22:332-346.
    • (2003) Int. J. Antimicrob. Agents , vol.22 , pp. 332-346
    • Kerboeuf, D.1    Blackhall, W.2    Kaminsky, R.3    von Samson-Himmelstjerna, G.4
  • 25
    • 0032518290 scopus 로고    scopus 로고
    • The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors
    • Kim R.B., Fromm M.F., Wandel C., Leake B., Wood A.J., Roden D.M., Wilkinson G.R. The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors. J. Clin. Invest. 1998, 101:289-294.
    • (1998) J. Clin. Invest. , vol.101 , pp. 289-294
    • Kim, R.B.1    Fromm, M.F.2    Wandel, C.3    Leake, B.4    Wood, A.J.5    Roden, D.M.6    Wilkinson, G.R.7
  • 26
    • 0023160924 scopus 로고
    • Biotransformation and induction: implications for toxicity, bioaccumulation and monitoring of environmental xenobiotics in fish
    • Kleinow K.M., Melancon M.J., Lech J.J. Biotransformation and induction: implications for toxicity, bioaccumulation and monitoring of environmental xenobiotics in fish. Environ. Health Perspect. 1987, 71:105-119.
    • (1987) Environ. Health Perspect. , vol.71 , pp. 105-119
    • Kleinow, K.M.1    Melancon, M.J.2    Lech, J.J.3
  • 27
    • 0036892767 scopus 로고    scopus 로고
    • Functional properties of a rainbow trout CYP3A27 expressed by recombinant baculovirus in insect cells
    • Lee S.J., Buhler D.R. Functional properties of a rainbow trout CYP3A27 expressed by recombinant baculovirus in insect cells. Drug Metab. Dispos. 2002, 30:1406-1412.
    • (2002) Drug Metab. Dispos. , vol.30 , pp. 1406-1412
    • Lee, S.J.1    Buhler, D.R.2
  • 28
    • 45449101104 scopus 로고    scopus 로고
    • ABC transporter modulation: a strategy to enhance the activity of macrocyclic lactone anthelmintics
    • Lespine A., Alvinerie M., Vercruysse J., Prichard R.K., Geldhof P. ABC transporter modulation: a strategy to enhance the activity of macrocyclic lactone anthelmintics. Trends Parasitol. 2008, 24:293-298.
    • (2008) Trends Parasitol. , vol.24 , pp. 293-298
    • Lespine, A.1    Alvinerie, M.2    Vercruysse, J.3    Prichard, R.K.4    Geldhof, P.5
  • 30
    • 0031851557 scopus 로고    scopus 로고
    • The fate of organic xenobiotics in aquatic ecosystems: quantitative and qualitative differences in biotransformation by invertebrates and fish. Comparative biochemistry and physiology. Part A
    • Livingstone D.R. The fate of organic xenobiotics in aquatic ecosystems: quantitative and qualitative differences in biotransformation by invertebrates and fish. Comparative biochemistry and physiology. Part A. Molecular & integrative physiology 1998, 120:43-49.
    • (1998) Molecular & integrative physiology , vol.120 , pp. 43-49
    • Livingstone, D.R.1
  • 31
    • 72049101172 scopus 로고    scopus 로고
    • Gene expression analysis of the ABC efflux transporters in rainbow trout (Oncorhynchus mykiss), comparative biochemistry and physiology
    • Loncar J., Popovic M., Zaja R., Smital T. Gene expression analysis of the ABC efflux transporters in rainbow trout (Oncorhynchus mykiss), comparative biochemistry and physiology. Toxicology & pharmacology: CBP 2010, 151:209-215.
    • (2010) Toxicology & pharmacology: CBP , vol.151 , pp. 209-215
    • Loncar, J.1    Popovic, M.2    Zaja, R.3    Smital, T.4
  • 32
    • 36749019114 scopus 로고    scopus 로고
    • Characterization of Phase I biotransformation enzymes in coho salmon (Oncorhynchus kisutch), comparative biochemistry and physiology
    • Matsuo A.Y., Gallagher E.P., Trute M., Stapleton P.L., Levado R., Schlenk D. Characterization of Phase I biotransformation enzymes in coho salmon (Oncorhynchus kisutch), comparative biochemistry and physiology. Toxicology & pharmacology: CBP 2008, 147:78-84.
    • (2008) Toxicology & pharmacology: CBP , vol.147 , pp. 78-84
    • Matsuo, A.Y.1    Gallagher, E.P.2    Trute, M.3    Stapleton, P.L.4    Levado, R.5    Schlenk, D.6
  • 33
    • 31344474852 scopus 로고    scopus 로고
    • The xenoestrogen 4-nonylphenol modulates hepatic gene expression of pregnane X receptor, aryl hydrocarbon receptor, CYP3A and CYP1A1 in juvenile Atlantic salmon (Salmo salar), comparative biochemistry and physiology
    • Meucci V., Arukwe A. The xenoestrogen 4-nonylphenol modulates hepatic gene expression of pregnane X receptor, aryl hydrocarbon receptor, CYP3A and CYP1A1 in juvenile Atlantic salmon (Salmo salar), comparative biochemistry and physiology. Toxicology & pharmacology: CBP 2006, 142:142-150.
    • (2006) Toxicology & pharmacology: CBP , vol.142 , pp. 142-150
    • Meucci, V.1    Arukwe, A.2
  • 34
    • 0024497781 scopus 로고
    • Purification and characterization of hepatic steroid hydroxylases from untreated rainbow trout
    • Miranda C.L., Wang J.L., Henderson M.C., Buhler D.R. Purification and characterization of hepatic steroid hydroxylases from untreated rainbow trout. Arch. Biochem. Biophys. 1989, 268:227-238.
    • (1989) Arch. Biochem. Biophys. , vol.268 , pp. 227-238
    • Miranda, C.L.1    Wang, J.L.2    Henderson, M.C.3    Buhler, D.R.4
  • 35
    • 33644777840 scopus 로고    scopus 로고
    • Multidrug resistance protein 1 (MRP1, ABCC1) mediates resistance to mitoxantrone via glutathione-dependent drug efflux
    • Morrow C.S., Peklak-Scott C., Bishwokarma B., Kute T.E., Smitherman P.K., Townsend A.J. Multidrug resistance protein 1 (MRP1, ABCC1) mediates resistance to mitoxantrone via glutathione-dependent drug efflux. Mol. Pharmacol. 2006, 69:1499-1505.
    • (2006) Mol. Pharmacol. , vol.69 , pp. 1499-1505
    • Morrow, C.S.1    Peklak-Scott, C.2    Bishwokarma, B.3    Kute, T.E.4    Smitherman, P.K.5    Townsend, A.J.6
  • 38
    • 0036223831 scopus 로고    scopus 로고
    • Summary of information on human CYP enzymes: human P450 metabolism data
    • Rendic S. Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metab. Rev. 2002, 34:83-448.
    • (2002) Drug Metab. Rev. , vol.34 , pp. 83-448
    • Rendic, S.1
  • 40
    • 2942541571 scopus 로고    scopus 로고
    • Identification of the multidrug resistance-associated protein (mrp) related gene in red mullet (Mullus barbatus)
    • Sauerborn R., Polancec D.S., Zaja R., Smital T. Identification of the multidrug resistance-associated protein (mrp) related gene in red mullet (Mullus barbatus). Mar. Environ. Res. 2004, 58:199-204.
    • (2004) Mar. Environ. Res. , vol.58 , pp. 199-204
    • Sauerborn, R.1    Polancec, D.S.2    Zaja, R.3    Smital, T.4
  • 41
    • 0037457802 scopus 로고    scopus 로고
    • Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview
    • Schinkel A.H., Jonker J.W. Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview. Adv. Drug Deliv. Rev. 2003, 55:3-29.
    • (2003) Adv. Drug Deliv. Rev. , vol.55 , pp. 3-29
    • Schinkel, A.H.1    Jonker, J.W.2
  • 43
    • 40949121607 scopus 로고    scopus 로고
    • ABC multidrug transporters: structure, function and role in chemoresistance
    • Sharom F.J. ABC multidrug transporters: structure, function and role in chemoresistance. Pharmacogenomics 2008, 9:105-127.
    • (2008) Pharmacogenomics , vol.9 , pp. 105-127
    • Sharom, F.J.1
  • 45
    • 0036139443 scopus 로고    scopus 로고
    • Regio-specific hydroxylation of nonylphenol and the involvement of CYP2K- and CYP2M-like iso-enzymes in Atlantic salmon (Salmo salar)
    • Thibaut R., Debrauwer L., Perdu E., Goksoyr A., Cravedi J.P., Arukwe A. Regio-specific hydroxylation of nonylphenol and the involvement of CYP2K- and CYP2M-like iso-enzymes in Atlantic salmon (Salmo salar). Aquat. Toxicol. 2002, 56:177-190.
    • (2002) Aquat. Toxicol. , vol.56 , pp. 177-190
    • Thibaut, R.1    Debrauwer, L.2    Perdu, E.3    Goksoyr, A.4    Cravedi, J.P.5    Arukwe, A.6
  • 46
    • 38549084107 scopus 로고    scopus 로고
    • Identification and localization of a putative ATP-binding cassette transporter in sea lice (Lepeophtheirus salmonis) and host Atlantic salmon (Salmo salar)
    • Tribble N.D., Burka J.F., Kibenge F.S., Wright G.M. Identification and localization of a putative ATP-binding cassette transporter in sea lice (Lepeophtheirus salmonis) and host Atlantic salmon (Salmo salar). Parasitology 2008, 135:243-255.
    • (2008) Parasitology , vol.135 , pp. 243-255
    • Tribble, N.D.1    Burka, J.F.2    Kibenge, F.S.3    Wright, G.M.4
  • 47
    • 0008632564 scopus 로고
    • Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine
    • Ueda K., Cardarelli C., Gottesman M.M., Pastan I. Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine. Proc. Natl. Acad. Sci. U.S.A. 1987, 84:3004-3008.
    • (1987) Proc. Natl. Acad. Sci. U.S.A. , vol.84 , pp. 3004-3008
    • Ueda, K.1    Cardarelli, C.2    Gottesman, M.M.3    Pastan, I.4
  • 48
    • 0023929834 scopus 로고
    • Human liver microsomal steroid metabolism: identification of the major microsomal steroid hormone 6 beta-hydroxylase cytochrome P-450 enzyme
    • Waxman D.J., Attisano C., Guengerich F.P., Lapenson D.P. Human liver microsomal steroid metabolism: identification of the major microsomal steroid hormone 6 beta-hydroxylase cytochrome P-450 enzyme. Arch. Biochem. Biophys. 1988, 263:424-436.
    • (1988) Arch. Biochem. Biophys. , vol.263 , pp. 424-436
    • Waxman, D.J.1    Attisano, C.2    Guengerich, F.P.3    Lapenson, D.P.4
  • 49
    • 0021947032 scopus 로고
    • Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes
    • Waxman D.J., Dannan G.A., Guengerich F.P. Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes. Biochemistry 1985, 24:4409-4417.
    • (1985) Biochemistry , vol.24 , pp. 4409-4417
    • Waxman, D.J.1    Dannan, G.A.2    Guengerich, F.P.3
  • 50
    • 0020565783 scopus 로고
    • Purified form of cytochrome P-450 from rainbow trout with high activity toward conversion of aflatoxin B1 to aflatoxin B1-2,3-epoxide
    • Williams D.E., Buhler D.R. Purified form of cytochrome P-450 from rainbow trout with high activity toward conversion of aflatoxin B1 to aflatoxin B1-2,3-epoxide. Cancer Res. 1983, 43:4752-4756.
    • (1983) Cancer Res. , vol.43 , pp. 4752-4756
    • Williams, D.E.1    Buhler, D.R.2
  • 51
    • 23344450788 scopus 로고    scopus 로고
    • Induction of phase I, II and III drug metabolism/transport by xenobiotics
    • Xu C., Li C.Y., Kong A.N. Induction of phase I, II and III drug metabolism/transport by xenobiotics. Arch. Pharm. Res. 2005, 28:249-268.
    • (2005) Arch. Pharm. Res. , vol.28 , pp. 249-268
    • Xu, C.1    Li, C.Y.2    Kong, A.N.3
  • 52
    • 39149128746 scopus 로고    scopus 로고
    • Development and characterization of P-glycoprotein 1 (Pgp1, ABCB1)-mediated doxorubicin-resistant PLHC-1 hepatoma fish cell line
    • Zaja R., Caminada D., Loncar J., Fent K., Smital T. Development and characterization of P-glycoprotein 1 (Pgp1, ABCB1)-mediated doxorubicin-resistant PLHC-1 hepatoma fish cell line. Toxicol. Appl. Pharmacol. 2008, 227:207-218.
    • (2008) Toxicol. Appl. Pharmacol. , vol.227 , pp. 207-218
    • Zaja, R.1    Caminada, D.2    Loncar, J.3    Fent, K.4    Smital, T.5
  • 53
    • 79952358750 scopus 로고    scopus 로고
    • First characterization of fish P-glycoprotein (abcb1) substrate specificity using determinations of its ATPase activity and calcein-AM assay with PLHC-1/dox cell line
    • Zaja R., Loncar J., Popovic M., Smital T. First characterization of fish P-glycoprotein (abcb1) substrate specificity using determinations of its ATPase activity and calcein-AM assay with PLHC-1/dox cell line. Aquat. Toxicol. 2011, 103:53-62.
    • (2011) Aquat. Toxicol. , vol.103 , pp. 53-62
    • Zaja, R.1    Loncar, J.2    Popovic, M.3    Smital, T.4
  • 55
    • 0030808483 scopus 로고    scopus 로고
    • Identification of cytochrome P4503A as the major enzyme sub-family responsible for the metabolism of 22,23-dihydro-13-O-[(2-methoxyethoxy)methyl]-avermectin B1 aglycone by rat liver microsomes
    • Zeng Z., Andrew N.W., Halley B.A. Identification of cytochrome P4503A as the major enzyme sub-family responsible for the metabolism of 22,23-dihydro-13-O-[(2-methoxyethoxy)methyl]-avermectin B1 aglycone by rat liver microsomes. Xenobiotica 1997, 27:985-994.
    • (1997) Xenobiotica , vol.27 , pp. 985-994
    • Zeng, Z.1    Andrew, N.W.2    Halley, B.A.3
  • 56
    • 40149086197 scopus 로고    scopus 로고
    • Biomarker induction in tropical fish species on the Northwest Shelf of Australia by produced formation water
    • Zhu S., King S.C., Haasch M.L. Biomarker induction in tropical fish species on the Northwest Shelf of Australia by produced formation water. Mar. Environ. Res. 2008, 65:315-324.
    • (2008) Mar. Environ. Res. , vol.65 , pp. 315-324
    • Zhu, S.1    King, S.C.2    Haasch, M.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.