Sustained platelet-derived growth factor receptor α signaling in osteoblasts results in craniosynostosis by overactivating the phospholipase C-γ pathway

Molecular and Cellular Biology

Volumn 29, Issue 3, 2009, Pages 881-891

  Moenning, Anne ^a   Jager, Richard ^a   Egert, Angela ^a   Kress, Wolfram ^b   Wardelmann, Eva ^a   Schorle, Hubert ^a  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHOLIPASE C GAMMA; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; CRE RECOMBINASE; INTEGRASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE MATRIX; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; CRANIOFACIAL SYNOSTOSIS; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; MOUSE; NEURAL CREST CELL; NONHUMAN; OSSIFICATION; OSTEOBLAST; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SKULL SUTURE; STEM CELL; TRANSGENIC MOUSE; ANIMAL; CONGENITAL MALFORMATION; CYTOLOGY; DNA SEQUENCE; ENZYME ACTIVATION; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION; NEURAL CREST; PATHOLOGY; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SKULL; TRANSGENE; WESTERN BLOTTING;

MUS; MUS MUSCULUS;

ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL PROLIFERATION; CRANIOSYNOSTOSES; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HUMANS; INTEGRASES; MICE; MICE, TRANSGENIC; MUTATION; NEURAL CREST; OSTEOBLASTS; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; SIGNAL TRANSDUCTION; SKULL; STEM CELLS; TRANSGENES;

EID: 59249087617     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00885-08     Document Type: Article

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