3,4,5-Tricaffeoylquinic acid inhibits tumor necrosis factor-α- stimulated production of inflammatory mediators in keratinocytes via suppression of Akt- and NF-κB-pathways

International Immunopharmacology

Volumn 11, Issue 11, 2011, Pages 1715-1723

  Lee, Chung Soo ^a   Lee, Seon Ae ^a   Kim, Yun Jeong ^a   Seo, Seong Jun ^b   Lee, Min Won ^a  

^a Chung Ang University   (South Korea)

^b Chung Ang University College of Medicine   (South Korea)

Author keywords

3,4,5 Tricaffeoylquinic acid; Akt pathway; Inflammatory mediator production; Keratinocytes; Tumor necrosis factor

Indexed keywords

3 (4 TERT BUTYLPHENYLSULFONYL) 2 PROPENENITRILE; 3,4,5 TRICAFFEOYLQUINIC ACID; ACETYLCYSTEINE; CUTANEOUS T CELL ATTRACTING CHEMOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 8; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; QUINIC ACID; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; ATOPIC DERMATITIS; CELL VIABILITY; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFLAMMATION; KERATINOCYTE; PRIORITY JOURNAL; SKIN INFLAMMATION; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

ANTI-INFLAMMATORY AGENTS; BLOTTING, WESTERN; CELL LINE; CELL NUCLEUS; CELL SURVIVAL; CHLOROGENIC ACID; CYTOSOL; DERMATITIS, ATOPIC; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; ILEX; IMMUNOLOGIC FACTORS; KERATINOCYTES; NF-KAPPA B; PLANT BARK; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SKIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80054986736     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2011.06.003     Document Type: Article

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